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Gene: Klf5 (Kruppel-like factor 5) Rattus norvegicus
Symbol: Klf5
Name: Kruppel-like factor 5
RGD ID: 621446
Description: Exhibits sequence-specific DNA binding activity and transcription factor binding activity. Involved in several processes, including cellular response to peptide; negative regulation of cardiac vascular smooth muscle cell differentiation; and positive regulation of cell population proliferation. Predicted to localize to Golgi apparatus; nuclear lumen; and transcription regulator complex. Orthologous to human KLF5 (Kruppel like factor 5); INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: basic transcription element binding protein 2; basic transcription element binding protein BTEB2; Bteb2; IKLF; Krueppel-like factor 5; Kruppel-like factor 5 (intestinal)
Homo sapiens (human) : KLF5 (Kruppel like factor 5)  HGNC  Alliance
Mus musculus (house mouse) : Klf5 (Kruppel-like factor 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf5 (Kruppel like factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF5 (Kruppel like factor 5)
Canis lupus familiaris (dog) : KLF5 (Kruppel like factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf5 (Kruppel like factor 5)
Sus scrofa (pig) : KLF5 (Kruppel like factor 5)
Chlorocebus sabaeus (African green monkey) : KLF5 (Kruppel like factor 5)
Heterocephalus glaber (naked mole-rat) : Klf5 (Kruppel like factor 5)
more info ...
Related Pseudogenes: Klf5-ps1   Klf5-ps2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01583,703,796 - 83,722,921 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1583,703,791 - 83,722,921 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01587,212,719 - 87,231,850 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41583,103,177 - 83,118,363 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11583,121,895 - 83,132,620 (+)NCBI
Celera1575,305,416 - 75,320,302 (+)NCBICelera
Cytogenetic Map15q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Klf5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621446
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.