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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621446
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Klf5
Name: Kruppel-like factor 5
Acc ID: CHEBI:34578
Term: Bisphenol A diglycidyl ether
Definition: A diarylmethane that has formula C21H24O4.
Chemical ID: MESH:C019273
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Klf5multiple interactionsEXP 6480464CTD2, 2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxyprostaglandin J2 inhibits the reaction [AGT protein results in increased expression of KLF5 mRNA]], 2, 2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxyprostaglandin J2 inhibits the reaction [AGT protein results in increased expression of KLF5 protein]], 2, 2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 mRNA]], 2, 2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 protein]]

PMID:25874449
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.