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RGD ID: 621446
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Klf5
Name: Kruppel-like factor 5
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Klf5increases expressionISORGD:13459276480464CTDtrichostatin A results in increased expression of KLF5 mRNA

PMID:20678512, PMID:24935251, PMID:26272509
Klf5multiple interactionsISORGD:13459276480464CTD[Decitabine co-treated with trichostatin A] results in increased expression of KLF5 mRNA, [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KLF5 mRNA

PMID:20678512, PMID:27188386
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.