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GENE - TERM ANNOTATION REPORT

RGD ID: 621446
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Klf5
Name: Kruppel-like factor 5
Acc ID: GO:0014901
Term: satellite cell activation involved in skeletal muscle regeneration
Definition: The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.
Definition Source(s): GOC:mtg_muscle
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Klf5 ISORGD:15510831624291RGDMGI:MGI:4353154, MGI:MGI:4421792 (MGI:MGI:5823533, PMID:27743478)

MGI:MGI:5823533, PMID:27743478
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.