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Gene: Col4a1 (collagen type IV alpha 1 chain) Rattus norvegicus
Symbol: Col4a1
Name: collagen type IV alpha 1 chain
Description: Predicted to have extracellular matrix structural constituent conferring tensile strength and platelet-derived growth factor binding activity. Involved in epithelial cell differentiation. Predicted to localize to collagen type IV trimer and extracellular space. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in COL4A1-related familial vascular leukoencephalopathy; myocardial infarction; and retinal arterial tortuosity. Orthologous to human COL4A1 (collagen type IV alpha 1 chain); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine.
Type: protein-coding
Also known as: alpha 1 type IV collagen; collagen alpha-1(IV) chain; collagen, type IV, alpha 1; LOC290905; procollagen, type IV, alpha 1
Homo sapiens (human) : COL4A1 (collagen type IV alpha 1 chain)  HGNC  Alliance
Mus musculus (house mouse) : Col4a1 (collagen, type IV, alpha 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col4a1 (collagen type IV alpha 1 chain)
Pan paniscus (bonobo/pygmy chimpanzee) : COL4A1 (collagen type IV alpha 1 chain)
Canis lupus familiaris (dog) : COL4A1 (collagen type IV alpha 1 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col4a1 (collagen type IV alpha 1 chain)
Sus scrofa (pig) : COL4A1 (collagen type IV alpha 1 chain)
Chlorocebus sabaeus (African green monkey) : COL4A1 (collagen type IV alpha 1 chain)
Heterocephalus glaber (naked mole-rat) : Col4a1 (collagen type IV alpha 1 chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01683,522,162 - 83,632,153 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1683,522,162 - 83,632,153 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01682,987,857 - 83,097,435 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41683,045,183 - 83,157,835 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11683,031,106 - 83,143,679 (+)NCBI
Celera1675,981,231 - 76,092,476 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Col4a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307148
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.