Gene: Plk4 (polo-like kinase 4) Rattus norvegicus
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Symbol: Plk4
Name: polo-like kinase 4
Description: Predicted to have identical protein binding activity and protein serine/threonine kinase activity; predicted to be involved in several processes, including microtubule organizing center organization, positive regulation of centriole replication, and protein phosphorylation; predicted to localize to the cytoplasm and intracellular organelle; orthologous to human PLK4 (polo like kinase 4); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC310344; PLK-4; polo-like kinase 4 (Drosophila); serine/threonine-protein kinase PLK4; serine/threonine-protein kinase Sak
Orthologs:
Homo sapiens (human) : PLK4 (polo like kinase 4)  HGNC  Alliance
Mus musculus (house mouse) : Plk4 (polo like kinase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plk4 (polo like kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PLK4 (polo like kinase 4)
Canis lupus familiaris (dog) : PLK4 (polo like kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plk4 (polo like kinase 4)
Sus scrofa (pig) : PLK4 (polo like kinase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02127,686,911 - 127,705,518 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02147,289,950 - 147,308,585 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42127,760,508 - 127,779,640 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12127,710,374 - 127,729,098 (+)NCBI
Celera2118,710,474 - 118,728,860 (+)NCBICelera
Cytogenetic Map2q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Plk4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305390
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.