Arl6ip5 (ADP-ribosylation factor like GTPase 6 interacting protein 5) - Rat Genome Database

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Gene: Arl6ip5 (ADP-ribosylation factor like GTPase 6 interacting protein 5) Rattus norvegicus
Analyze
Symbol: Arl6ip5
Name: ADP-ribosylation factor like GTPase 6 interacting protein 5
RGD ID: 708572
Description: Enables transmembrane transporter binding activity. Involved in negative regulation of transport and regulation of neurotransmitter uptake. Predicted to be located in cytoskeleton and endoplasmic reticulum membrane. Predicted to be active in plasma membrane and presynaptic cytosol. Orthologous to human ARL6IP5 (ADP ribosylation factor like GTPase 6 interacting protein 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ADP-ribosylation factor-like 6 interacting protein 5; ADP-ribosylation factor-like protein 6-interacting protein 5; ADP-ribosylation-like factor 6 interacting protein 5; aip-5; ARL-6-interacting protein 5; glutamate transporter EAAC1 interacting protein; glutamate transporter EAAC1-interacting protein; Gtrap3-18; PRA1 family protein 3; prenylated Rab acceptor protein 2; protein JWa
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24129,810,650 - 129,838,628 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4129,810,645 - 129,838,608 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4135,240,121 - 135,262,313 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04131,021,163 - 131,043,358 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04129,639,108 - 129,661,304 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04129,574,363 - 129,598,240 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4129,574,264 - 129,598,915 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04194,077,777 - 194,099,732 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44131,929,503 - 131,953,033 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14132,174,335 - 132,198,662 (+)NCBI
Celera4118,691,862 - 118,713,984 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
5-formyltetrahydrofolic acid  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetylsalicylic acid  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (ISO)
bexarotene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
carbon nanotube  (ISO)
chloropicrin  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
etoposide  (ISO)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
hemin  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
kojic acid  (ISO)
Mesaconitine  (EXP)
methylmercury chloride  (ISO)
morphine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
nickel subsulfide  (EXP)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phoxim  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
trovafloxacin  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18. Lin CI, etal., Nature 2001 Mar 1;410(6824):84-8.
3. Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1. Liu Y, etal., J Biol Chem. 2008 Mar 7;283(10):6561-71. doi: 10.1074/jbc.M708096200. Epub 2007 Dec 20.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11096102   PMID:12119102   PMID:14751295   PMID:15489334   PMID:18363836   PMID:18387645   PMID:18504258   PMID:18684713   PMID:19946888   PMID:21600884   PMID:22871113   PMID:23376485  


Genomics

Comparative Map Data
Arl6ip5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24129,810,650 - 129,838,628 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4129,810,645 - 129,838,608 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4135,240,121 - 135,262,313 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04131,021,163 - 131,043,358 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04129,639,108 - 129,661,304 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04129,574,363 - 129,598,240 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4129,574,264 - 129,598,915 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04194,077,777 - 194,099,732 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44131,929,503 - 131,953,033 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14132,174,335 - 132,198,662 (+)NCBI
Celera4118,691,862 - 118,713,984 (+)NCBICelera
Cytogenetic Map4q34NCBI
ARL6IP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38369,084,937 - 69,106,092 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl369,084,937 - 69,106,092 (+)EnsemblGRCh38hg38GRCh38
GRCh37369,134,088 - 69,155,243 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36369,216,780 - 69,237,929 (+)NCBINCBI36Build 36hg18NCBI36
Build 34369,216,779 - 69,237,927NCBI
Celera369,062,198 - 69,083,349 (+)NCBICelera
Cytogenetic Map3p14.1NCBI
HuRef369,135,165 - 69,156,317 (+)NCBIHuRef
CHM1_1369,085,302 - 69,106,451 (+)NCBICHM1_1
T2T-CHM13v2.0369,121,729 - 69,142,904 (+)NCBIT2T-CHM13v2.0
Arl6ip5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39697,187,753 - 97,210,276 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl697,187,650 - 97,210,276 (+)EnsemblGRCm39 Ensembl
GRCm38697,210,792 - 97,233,315 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl697,210,689 - 97,233,315 (+)EnsemblGRCm38mm10GRCm38
MGSCv37697,160,786 - 97,183,309 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36697,176,255 - 97,198,778 (+)NCBIMGSCv36mm8
Celera699,069,909 - 99,092,703 (+)NCBICelera
Cytogenetic Map6D3NCBI
cM Map644.91NCBI
Arl6ip5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542118,747,729 - 18,766,408 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542118,747,729 - 18,766,559 (-)NCBIChiLan1.0ChiLan1.0
ARL6IP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1369,044,998 - 69,065,627 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0369,020,908 - 69,042,065 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1370,387,605 - 70,408,909 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl370,387,581 - 70,408,909 (+)Ensemblpanpan1.1panPan2
ARL6IP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12022,632,613 - 22,653,894 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2022,633,808 - 22,653,870 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2022,607,070 - 22,628,807 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02022,658,421 - 22,679,823 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2022,657,809 - 22,679,724 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12022,352,356 - 22,373,877 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02022,695,566 - 22,717,292 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02022,765,439 - 22,787,039 (-)NCBIUU_Cfam_GSD_1.0
Arl6ip5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049421,525,497 - 1,549,923 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366031,524,625 - 1,549,923 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366031,524,959 - 1,549,923 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL6IP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1350,509,519 - 50,538,966 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11350,509,777 - 50,538,004 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21355,664,791 - 55,668,851 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARL6IP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12230,110,881 - 30,132,186 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2230,111,017 - 30,135,240 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041136,659,968 - 136,681,967 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arl6ip5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247733,666,072 - 3,688,094 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247733,666,255 - 3,685,446 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arl6ip5
163 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:342
Count of miRNA genes:207
Interacting mature miRNAs:252
Transcripts:ENSRNOT00000010185
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4103194656148194656Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4105789505150789505Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106649412151649412Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)4106805662151805662Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4109827074154827074Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4109827074154827074Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4116179486151161268Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4119428175157578333Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4119463257147278687Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4120260281147278687Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4120926564148090731Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000010185   ⟹   ENSRNOP00000010185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4129,810,645 - 129,838,608 (+)Ensembl
Rnor_6.0 Ensembl4129,574,264 - 129,598,915 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098178   ⟹   ENSRNOP00000096809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4129,810,645 - 129,837,994 (+)Ensembl
RefSeq Acc Id: NM_023972   ⟹   NP_076462
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24129,815,449 - 129,838,628 (+)NCBI
Rnor_6.04129,574,363 - 129,598,240 (+)NCBI
Rnor_5.04194,077,777 - 194,099,732 (+)NCBI
RGSC_v3.44131,929,503 - 131,953,033 (+)RGD
Celera4118,691,862 - 118,713,984 (+)RGD
Sequence:
RefSeq Acc Id: XM_039108327   ⟹   XP_038964255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24129,810,657 - 129,838,628 (+)NCBI
RefSeq Acc Id: XM_039108328   ⟹   XP_038964256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24129,810,650 - 129,838,628 (+)NCBI
RefSeq Acc Id: NP_076462   ⟸   NM_023972
- UniProtKB: Q9JKD1 (UniProtKB/Swiss-Prot),   Q9ES40 (UniProtKB/Swiss-Prot),   A6IBF8 (UniProtKB/TrEMBL),   A0A0H2UHF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000010185   ⟸   ENSRNOT00000010185
RefSeq Acc Id: XP_038964256   ⟸   XM_039108328
- Peptide Label: isoform X1
- UniProtKB: Q9ES40 (UniProtKB/Swiss-Prot),   Q9JKD1 (UniProtKB/Swiss-Prot),   A6IBF8 (UniProtKB/TrEMBL),   A0A0H2UHF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964255   ⟸   XM_039108327
- Peptide Label: isoform X1
- UniProtKB: Q9ES40 (UniProtKB/Swiss-Prot),   Q9JKD1 (UniProtKB/Swiss-Prot),   A6IBF8 (UniProtKB/TrEMBL),   A0A0H2UHF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000096809   ⟸   ENSRNOT00000098178

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ES40-F1-model_v2 AlphaFold Q9ES40 1-188 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693268
Promoter ID:EPDNEW_R3793
Type:multiple initiation site
Name:Arl6ip5_1
Description:ADP-ribosylation factor like GTPase 6 interacting protein 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04129,574,337 - 129,574,397EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708572 AgrOrtholog
BioCyc Gene G2FUF-43603 BioCyc
Ensembl Genes ENSRNOG00000006818 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055003864 UniProtKB/Swiss-Prot
  ENSRNOG00060004182 UniProtKB/Swiss-Prot
  ENSRNOG00065023811 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000010185 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000010185.7 UniProtKB/Swiss-Prot
  ENSRNOT00000098178.1 UniProtKB/TrEMBL
  ENSRNOT00055006118 UniProtKB/Swiss-Prot
  ENSRNOT00060006981 UniProtKB/Swiss-Prot
  ENSRNOT00065040828 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6922366 IMAGE-MGC_LOAD
InterPro Prenylated_rab_accept_PRA1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:66028 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72809 IMAGE-MGC_LOAD
NCBI Gene 66028 ENTREZGENE
PANTHER PRA1 FAMILY PROTEIN 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12859 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PRA1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arl6ip5 PhenoGen
RatGTEx ENSRNOG00000006818 RatGTEx
  ENSRNOG00055003864 RatGTEx
  ENSRNOG00060004182 RatGTEx
  ENSRNOG00065023811 RatGTEx
UniProt A0A0H2UHF6 ENTREZGENE, UniProtKB/TrEMBL
  A6IBF7_RAT UniProtKB/TrEMBL
  A6IBF8 ENTREZGENE, UniProtKB/TrEMBL
  PRAF3_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JKD1 ENTREZGENE
UniProt Secondary Q9JKD1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Arl6ip5  ADP-ribosylation factor like GTPase 6 interacting protein 5  Arl6ip5  ADP-ribosylation factor-like 6 interacting protein 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-05-21 Arl6ip5  ADP-ribosylation factor-like 6 interacting protein 5  Arl6ip5  ADP-ribosylation-like factor 6 interacting protein 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Arl6ip5  ADP-ribosylation-like factor 6 interacting protein 5  Arl6ip5  ADP-ribosylation factor-like 6 interacting protein 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Arl6ip5  ADP-ribosylation factor-like 6 interacting protein 5  Gtrap3-18  glutamate transporter EAAC1 interacting protein  Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds the carboxy-terminal intracellular domain of glutamate transporter protein EAAC1 1299537