Arl6ip5 (ADP-ribosylation factor-like 6 interacting protein 5) - Rat Genome Database
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Gene: Arl6ip5 (ADP-ribosylation factor-like 6 interacting protein 5) Mus musculus
Analyze
Symbol: Arl6ip5
Name: ADP-ribosylation factor-like 6 interacting protein 5
RGD ID: 1331961
MGI Page MGI
Description: Is expressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human ARL6IP5 (ADP ribosylation factor like GTPase 6 interacting protein 5); INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5930404D22Rik; add; addicsin; addiscin; ADP-ribosylation factor-like protein 6-interacting protein 5; ADP-ribosylation-like factor 6 interacting protein 5; Ai; Aip-5; ARL-6-interacting protein 5; AV001879; glutamate transporter EAAC1-interacting protein; Gtrap3; Gtrap3-18; JWa; PRA1 family protein 3; prenylated Rab acceptor protein 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39697,187,753 - 97,210,276 (+)NCBIGRCm39mm39
GRCm39 Ensembl697,187,650 - 97,210,276 (+)Ensembl
GRCm38697,210,792 - 97,233,315 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl697,210,689 - 97,233,315 (+)EnsemblGRCm38mm10GRCm38
MGSCv37697,160,786 - 97,183,309 (+)NCBIGRCm37mm9NCBIm37
MGSCv36697,176,255 - 97,198,778 (+)NCBImm8
Celera699,069,909 - 99,092,703 (+)NCBICelera
Cytogenetic Map6D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3-methylcholanthrene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
5-formyltetrahydrofolic acid  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP)
acetylsalicylic acid  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (EXP)
bexarotene  (ISO)
bisphenol A  (ISO)
Brodifacoum  (ISO)
carbon nanotube  (EXP)
chloropicrin  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
etoposide  (ISO)
fipronil  (ISO)
flutamide  (ISO)
folic acid  (EXP)
gentamycin  (ISO)
hemin  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
kojic acid  (ISO)
methylmercury chloride  (ISO)
morphine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nickel subsulfide  (ISO)
oxaliplatin  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phoxim  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10508919   PMID:11042159   PMID:11076861   PMID:11591653   PMID:12119102   PMID:12438930   PMID:12477932   PMID:12562531   PMID:12904583   PMID:14610273  
PMID:15489334   PMID:16005150   PMID:16141072   PMID:16141073   PMID:17462538   PMID:17967808   PMID:18167356   PMID:18684713   PMID:18799673   PMID:18799693   PMID:19208635   PMID:19521500  
PMID:21267068   PMID:21677750   PMID:21873635   PMID:22210510   PMID:22461904   PMID:24628733   PMID:24680664   PMID:25321471   PMID:25432888   PMID:26220341   PMID:28428137   PMID:28904020  
PMID:32325033  


Genomics

Comparative Map Data
Arl6ip5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39697,187,753 - 97,210,276 (+)NCBIGRCm39mm39
GRCm39 Ensembl697,187,650 - 97,210,276 (+)Ensembl
GRCm38697,210,792 - 97,233,315 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl697,210,689 - 97,233,315 (+)EnsemblGRCm38mm10GRCm38
MGSCv37697,160,786 - 97,183,309 (+)NCBIGRCm37mm9NCBIm37
MGSCv36697,176,255 - 97,198,778 (+)NCBImm8
Celera699,069,909 - 99,092,703 (+)NCBICelera
Cytogenetic Map6D3NCBI
ARL6IP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl369,084,937 - 69,106,092 (+)EnsemblGRCh38hg38GRCh38
GRCh38369,084,937 - 69,106,092 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37369,134,088 - 69,155,243 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36369,216,780 - 69,237,929 (+)NCBINCBI36hg18NCBI36
Build 34369,216,779 - 69,237,927NCBI
Celera369,062,198 - 69,083,349 (+)NCBI
Cytogenetic Map3p14.1NCBI
HuRef369,135,165 - 69,156,317 (+)NCBIHuRef
CHM1_1369,085,302 - 69,106,451 (+)NCBICHM1_1
Arl6ip5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24129,810,650 - 129,838,628 (+)NCBI
Rnor_6.0 Ensembl4129,574,264 - 129,598,915 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04129,574,363 - 129,598,240 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04194,077,777 - 194,099,732 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44131,929,503 - 131,953,033 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14132,174,335 - 132,198,662 (+)NCBI
Celera4118,691,862 - 118,713,984 (+)NCBICelera
Cytogenetic Map4q34NCBI
Arl6ip5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542118,747,729 - 18,766,408 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542118,747,729 - 18,766,559 (-)NCBIChiLan1.0ChiLan1.0
ARL6IP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1370,387,605 - 70,408,909 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl370,387,581 - 70,408,909 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0369,020,908 - 69,042,065 (+)NCBIMhudiblu_PPA_v0panPan3
ARL6IP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2022,633,808 - 22,653,870 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12022,632,613 - 22,653,894 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Arl6ip5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366031,524,959 - 1,549,923 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL6IP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1350,509,519 - 50,538,967 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11350,509,777 - 50,538,004 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21355,664,791 - 55,668,851 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARL6IP5
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12230,110,881 - 30,132,186 (+)NCBI
ChlSab1.1 Ensembl2230,111,017 - 30,135,240 (+)Ensembl
Arl6ip5
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247733,666,255 - 3,685,446 (+)NCBI

Position Markers
AV001879  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38697,232,921 - 97,233,055UniSTSGRCm38
MGSCv37697,182,915 - 97,183,049UniSTSGRCm37
Celera699,092,309 - 99,092,443UniSTS
Cytogenetic Map6D3UniSTS
Whitehead/MRC_RH6987.45UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined689005405123005603Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690795610124795846Mouse
11532719Sluc45_msusceptibility to lung cancer 45 (mouse)69260730698258933Mouse
4141578Obrq1_mobesity resistance QTL 1 (mouse)Not determined92607306112004738Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692607306146429238Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined695004651129004738Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696347325130347522Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696347325130347522Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96655951146633626Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96655951146633626Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696655951146633626Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:272
Count of miRNA genes:219
Interacting mature miRNAs:247
Transcripts:ENSMUST00000044681
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000044681   ⟹   ENSMUSP00000041503
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl697,210,689 - 97,233,315 (+)Ensembl
RefSeq Acc Id: NM_022992   ⟹   NP_075368
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39697,187,753 - 97,210,276 (+)NCBI
GRCm38697,210,792 - 97,233,315 (+)ENTREZGENE
MGSCv37697,160,786 - 97,183,309 (+)RGD
Celera699,069,909 - 99,092,703 (+)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_075368   ⟸   NM_022992
- UniProtKB: Q8R5J9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000041503   ⟸   ENSMUST00000044681

Promoters
RGD ID:6838949
Promoter ID:MM_KWN:47005
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000056870
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36697,160,594 - 97,161,094 (+)MPROMDB
RGD ID:6890518
Promoter ID:EPDNEW_M8710
Type:initiation region
Name:Arl6ip5_1
Description:Mus musculus ADP-ribosylation factor-like 6 interacting protein5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38697,210,795 - 97,210,855EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1929501 AgrOrtholog
Ensembl Genes ENSMUSG00000035199 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000041503 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000044681 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Prenylated_rab_accept_PRA1 UniProtKB/Swiss-Prot
KEGG Report mmu:65106 UniProtKB/Swiss-Prot
MGD MGI:1929501 ENTREZGENE
NCBI Gene 65106 ENTREZGENE
Pfam PRA1 UniProtKB/Swiss-Prot
PhenoGen Arl6ip5 PhenoGen
UniProt PRAF3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q8C2Q1 UniProtKB/Swiss-Prot
  Q9D838 UniProtKB/Swiss-Prot
  Q9DB37 UniProtKB/Swiss-Prot
  Q9WUG9 UniProtKB/Swiss-Prot