GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Arl6ip5 | affects expression | ISO | ARL6IP5 (Homo sapiens) | 6480464 | CTD | Tretinoin affects the expression of ARL6IP5 | PMID:16720286 | Arl6ip5 | increases expression | ISO | ARL6IP5 (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased expression of ARL6IP5 mRNA; Tretinoin results in increased expression of ARL6IP5 protein | PMID:16430862 PMID:16468075 PMID:16922813 PMID:33167477 | Arl6ip5 | increases response to substance | ISO | ARL6IP5 (Homo sapiens) | 6480464 | CTD | ARL6IP5 protein results in increased susceptibility to Tretinoin | PMID:16922813 | Arl6ip5 | multiple interactions | ISO | ARL6IP5 (Homo sapiens) | 6480464 | CTD | [Tretinoin co-treated with arsenic trioxide] results in increased expression of ARL6IP5 mRNA; ARL6IP5 protein affects the reaction [Tretinoin results in increased phosphorylation of MAPK1 protein]; ARL6IP5 protein affects the reaction [Tretinoin results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Tretinoin results in increased expression of ARL6IP5 mRNA] | PMID:16468075 PMID:16922813 | |
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