Dbn1 (drebrin 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Dbn1 (drebrin 1) Rattus norvegicus
Analyze
Symbol: Dbn1
Name: drebrin 1
RGD ID: 70885
Description: Enables actin filament binding activity; cytoskeletal motor inhibitor activity; and profilin binding activity. Involved in several processes, including positive regulation of cell development; regulation of nervous system process; and regulation of organelle organization. Located in several cellular components, including axon; dendrite; and postsynaptic actin cytoskeleton. Is active in glutamatergic synapse and postsynaptic membrane. Colocalizes with actin filament. Biomarker of Parkinson's disease; cognitive disorder; sciatic neuropathy; temporal lobe epilepsy; and transient cerebral ischemia. Orthologous to human DBN1 (drebrin 1); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: developmentally-regulated brain protein; drebrin; drebrin E
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2179,150,608 - 9,164,982 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl179,150,659 - 9,164,984 (+)Ensembl
Rnor_6.0179,679,511 - 9,693,878 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,679,628 - 9,693,820 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01711,788,527 - 11,802,863 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41715,194,687 - 15,208,660 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11715,194,686 - 15,208,660 (+)NCBI
Celera179,229,222 - 9,243,194 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
amiodarone  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
curcumin  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
D-glucose  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dioxygen  (ISO)
diuron  (EXP)
endosulfan  (EXP)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
etoposide  (ISO)
flavonoids  (EXP)
furan  (EXP)
gallic acid  (ISO)
glucose  (EXP)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
oxaliplatin  (EXP)
paracetamol  (ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenethyl caffeate  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
progesterone  (EXP,ISO)
quercetin  (ISO)
resveratrol  (ISO)
sarin  (ISO)
SB 415286  (EXP)
sevoflurane  (EXP)
sodium fluoride  (ISO)
streptozocin  (EXP)
temozolomide  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin filament organization  (IEA,ISO,ISS)
aging  (IEP)
brain development  (IEP)
cell communication by chemical coupling  (IEA,ISO)
cell communication by electrical coupling  (IEA,ISO)
cellular response to transforming growth factor beta stimulus  (IDA)
cellular response to tumor necrosis factor  (IDA)
cellular response to X-ray  (IEP)
cytoplasmic sequestering of protein  (IEA,ISO,ISS)
generation of neurons  (ISO)
in utero embryonic development  (IEA,ISO)
lung alveolus development  (IEP)
maintenance of protein location in cell  (IEA,ISO)
modulation of inhibitory postsynaptic potential  (IMP)
negative regulation of actin filament bundle assembly  (IDA)
negative regulation of locomotion involved in locomotory behavior  (IMP)
negative regulation of muscle filament sliding  (IDA)
nervous system development  (IEP)
neural precursor cell proliferation  (IEA,ISO)
neuron projection morphogenesis  (IBA)
positive regulation of axon extension  (IBA,IMP)
positive regulation of cell-substrate adhesion  (IDA)
positive regulation of dendritic spine morphogenesis  (IBA,IEA,IMP,ISO,ISS)
positive regulation of excitatory postsynaptic potential  (IMP)
positive regulation of neuron projection development  (IDA,IMP)
positive regulation of receptor localization to synapse  (IEA,ISO,ISS)
positive regulation of substrate adhesion-dependent cell spreading  (IDA)
positive regulation of synaptic plasticity  (IEA,ISO,ISS)
postsynaptic actin cytoskeleton organization  (IBA,IDA,IMP)
prepulse inhibition  (IMP)
regulation of actin filament polymerization  (IBA,IMP)
regulation of filopodium assembly  (IMP)
regulation of postsynaptic density protein 95 clustering  (IMP)
response to activity  (IEP)
response to xenobiotic stimulus  (IEP)
spermatogenesis  (IEP)

Cellular Component

Molecular Function

References

References - curated
1. Ambrosi C, etal., PLoS One. 2016 Jun 9;11(6):e0157073. doi: 10.1371/journal.pone.0157073. eCollection 2016.
2. Aoki C, etal., J Comp Neurol. 2005 Mar 21;483(4):383-402.
3. Aoki C, etal., J Comp Neurol. 2007 Dec 1;505(4):352-62.
4. Counts SE, etal., J Neuropathol Exp Neurol. 2006 Jun;65(6):592-601.
5. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. GOA data from the GO Consortium
7. Goel M, etal., Pflugers Arch. 2005 Oct;451(1):87-98. Epub 2005 Jul 16.
8. Gonzalez-Burgos I, etal., Neurosci Lett. 2011 Mar 24;491(3):216-20. doi: 10.1016/j.neulet.2011.01.043. Epub 2011 Jan 22.
9. Harigaya Y, etal., J Neurosci Res. 1996 Jan 1;43(1):87-92.
10. Hayashi K and Shirao T, J Neurosci. 1999 May 15;19(10):3918-25.
11. Hayashi K, etal., J Neurosci. 1996 Nov 15;16(22):7161-70.
12. Ikeda K, etal., Neurosci Lett. 1995 Jul 21;194(3):197-200.
13. Ishikawa R, etal., Biochem Biophys Res Commun. 2007 Jul 27;359(2):398-401. Epub 2007 May 25.
14. Ivanov A, etal., J Cell Sci. 2009 Feb 15;122(Pt 4):524-34. doi: 10.1242/jcs.033464. Epub 2009 Jan 27.
15. Julien C, etal., J Neurosci Res. 2008 Aug 1;86(10):2292-302. doi: 10.1002/jnr.21667.
16. Kobayashi R, etal., Neurosci Res. 2004 Jun;49(2):205-17.
17. Kobayashi S, etal., Neurosci Lett. 2001 Oct 5;311(3):165-8.
18. Kojima N, etal., Neuroscience. 2010 Jan 13;165(1):138-50. doi: 10.1016/j.neuroscience.2009.10.016. Epub 2009 Oct 24.
19. Kreis P, etal., PLoS One. 2013 Aug 5;8(8):e71957. doi: 10.1371/journal.pone.0071957. Print 2013.
20. Li MW, etal., Spermatogenesis. 2011 Apr;1(2):123-136.
21. Mammoto A, etal., Biochem Biophys Res Commun. 1998 Feb 4;243(1):86-9.
22. MGD Curation, June 12, 2002
23. MGD data from the GO Consortium
24. Mizui T, etal., J Neurochem. 2009 Apr;109(2):611-22. doi: 10.1111/j.1471-4159.2009.05993.x. Epub 2009 Feb 13.
25. NCBI rat LocusLink and RefSeq merged data July 26, 2002
26. Nishijima H, etal., Neuropathology. 2013 Aug;33(4):391-6. doi: 10.1111/neup.12009. Epub 2012 Dec 13.
27. Park H, etal., Neurosci Lett. 2009 Sep 18;461(2):95-9. doi: 10.1016/j.neulet.2009.06.027. Epub 2009 Jun 17.
28. Perez-Martinez M, etal., J Cell Sci. 2010 Apr 1;123(Pt 7):1160-70. doi: 10.1242/jcs.064238. Epub 2010 Mar 9.
29. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
30. RGD automated import pipeline for gene-chemical interactions
31. Saruki N, Masui. 1995 Dec;44(12):1639-47.
32. Sasaki Y, etal., J Neurochem. 1996 Mar;66(3):980-8.
33. Sbai O, etal., Hippocampus. 2012 Mar;22(3):477-93. doi: 10.1002/hipo.20914. Epub 2011 Jan 14.
34. Shim KS and Lubec G, Neurosci Lett. 2002 May 24;324(3):209-12.
35. Shimohama S, etal., Biochem Biophys Res Commun. 1998 Oct 9;251(1):394-8.
36. Shirai K, etal., Radiat Res. 2013 Jun;179(6):630-6. doi: 10.1667/RR3098.1. Epub 2013 Apr 11.
37. Shirao T, etal., Neuroreport 1992 Jan;3(1):109-12.
38. Song M, etal., Neuroscience. 2008 Mar 27;152(3):670-82. doi: 10.1016/j.neuroscience.2007.10.068. Epub 2008 Jan 19.
39. Takahashi H, etal., J Neurosci. 2003 Jul 23;23(16):6586-95.
40. Toda M, etal., Brain Res Dev Brain Res. 1999 May 14;114(2):193-200.
41. VanGuilder HD, etal., Neurobiol Dis. 2011 Jul;43(1):201-12. doi: 10.1016/j.nbd.2011.03.012. Epub 2011 Apr 1.
42. Yamada M, etal., J Histochem Cytochem. 2005 Jun;53(6):735-44.
43. Yamazaki H, etal., J Neurochem. 2014 Feb;128(4):507-22. doi: 10.1111/jnc.12486. Epub 2013 Nov 13.
44. Yang HJ, etal., Neurosci Lett. 2003 Nov 20;351(3):206-8.
Additional References at PubMed
PMID:11991718   PMID:12477932   PMID:15084279   PMID:16054392   PMID:16368245   PMID:16456930   PMID:17559090   PMID:18588530   PMID:18806788   PMID:20131911   PMID:20882566   PMID:23979715  
PMID:24327345   PMID:24465547   PMID:24625528   PMID:24720729   PMID:24814707   PMID:25002582   PMID:25468996   PMID:25865831   PMID:27996060   PMID:28553222   PMID:28865017   PMID:28865027  
PMID:28966017   PMID:29476059   PMID:30053369  


Genomics

Comparative Map Data
Dbn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2179,150,608 - 9,164,982 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl179,150,659 - 9,164,984 (+)Ensembl
Rnor_6.0179,679,511 - 9,693,878 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,679,628 - 9,693,820 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01711,788,527 - 11,802,863 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41715,194,687 - 15,208,660 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11715,194,686 - 15,208,660 (+)NCBI
Celera179,229,222 - 9,243,194 (+)NCBICelera
Cytogenetic Map17p14NCBI
DBN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5177,456,608 - 177,474,401 (-)EnsemblGRCh38hg38GRCh38
GRCh385177,456,610 - 177,480,368 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375176,883,611 - 176,900,635 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365176,816,220 - 176,833,271 (-)NCBINCBI36hg18NCBI36
Build 345176,816,219 - 176,832,805NCBI
Celera5171,601,010 - 171,618,030 (+)NCBI
Cytogenetic Map5q35.3NCBI
HuRef5171,803,862 - 171,820,946 (-)NCBIHuRef
CHM1_15176,316,642 - 176,333,751 (-)NCBICHM1_1
Dbn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391355,621,241 - 55,635,959 (-)NCBIGRCm39mm39
GRCm39 Ensembl1355,621,242 - 55,635,924 (-)Ensembl
GRCm381355,473,428 - 55,488,126 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1355,473,429 - 55,488,111 (-)EnsemblGRCm38mm10GRCm38
MGSCv371355,574,789 - 55,589,437 (-)NCBIGRCm37mm9NCBIm37
MGSCv361355,483,409 - 55,497,790 (-)NCBImm8
Celera1356,527,471 - 56,542,117 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.06NCBI
Dbn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540829,696,266 - 29,705,416 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540829,695,442 - 29,705,417 (-)NCBIChiLan1.0ChiLan1.0
DBN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15179,820,791 - 179,833,546 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5179,820,791 - 179,836,872 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05172,758,316 - 172,774,974 (-)NCBIMhudiblu_PPA_v0panPan3
DBN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1435,899,969 - 35,913,015 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl435,889,392 - 35,912,507 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha435,866,175 - 35,880,615 (+)NCBI
ROS_Cfam_1.0436,265,157 - 36,279,633 (+)NCBI
UMICH_Zoey_3.1436,090,417 - 36,104,899 (+)NCBI
UNSW_CanFamBas_1.0436,276,383 - 36,290,861 (+)NCBI
UU_Cfam_GSD_1.0436,785,850 - 36,800,327 (+)NCBI
Dbn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213122,710,677 - 122,722,558 (-)NCBI
SpeTri2.0NW_0049365971,735,589 - 1,751,628 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DBN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl280,479,460 - 80,496,873 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1280,480,603 - 80,495,797 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DBN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12379,468,010 - 79,484,603 (-)NCBI
ChlSab1.1 Ensembl2379,467,647 - 79,484,592 (-)Ensembl
Vero_WHO_p1.0NW_02366607510,659,367 - 10,676,337 (-)NCBI
Dbn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473312,616,537 - 12,631,967 (+)NCBI

Position Markers
RH128442  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2179,164,466 - 9,164,678 (+)MAPPERmRatBN7.2
Rnor_6.0179,693,366 - 9,693,577NCBIRnor6.0
Rnor_5.01711,802,350 - 11,802,561UniSTSRnor5.0
RGSC_v3.41715,208,441 - 15,208,652UniSTSRGSC3.4
Celera179,242,975 - 9,243,186UniSTS
RH 3.4 Map1776.4UniSTS
Cytogenetic Map17p14UniSTS
UniSTS:237020  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2179,164,659 - 9,164,756 (+)MAPPERmRatBN7.2
Rnor_6.0179,693,559 - 9,693,655NCBIRnor6.0
Rnor_5.01711,802,543 - 11,802,639UniSTSRnor5.0
RGSC_v3.41715,208,634 - 15,208,730UniSTSRGSC3.4
Celera179,243,168 - 9,243,264UniSTS
Cytogenetic Map17p14UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17211514921881669Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)17429913021293263Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17429913021293263Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1581553Pur14Proteinuria QTL 145.30.0001total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)17797996816317111Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:349
Count of miRNA genes:184
Interacting mature miRNAs:203
Transcripts:ENSRNOT00000019393, ENSRNOT00000019569
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 34 6 6 3 6 1 1 74 25 38 3 1
Low 3 9 50 34 16 34 7 10 10 3 8 7
Below cutoff 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000019393   ⟹   ENSRNOP00000019393
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl179,150,659 - 9,164,984 (+)Ensembl
Rnor_6.0 Ensembl179,679,665 - 9,693,083 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000019569   ⟹   ENSRNOP00000019569
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl179,150,659 - 9,164,984 (+)Ensembl
Rnor_6.0 Ensembl179,679,628 - 9,693,820 (+)Ensembl
RefSeq Acc Id: NM_031024   ⟹   NP_112286
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2179,150,713 - 9,164,686 (+)NCBI
Rnor_6.0179,679,612 - 9,693,585 (+)NCBI
Rnor_5.01711,788,527 - 11,802,863 (+)NCBI
RGSC_v3.41715,194,687 - 15,208,660 (+)RGD
Celera179,229,222 - 9,243,194 (+)RGD
Sequence:
RefSeq Acc Id: XM_006253655   ⟹   XP_006253717
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2179,150,608 - 9,164,979 (+)NCBI
Rnor_6.0179,679,511 - 9,693,878 (+)NCBI
Rnor_5.01711,788,527 - 11,802,863 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006253656   ⟹   XP_006253718
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2179,150,608 - 9,164,979 (+)NCBI
Rnor_6.0179,679,512 - 9,693,878 (+)NCBI
Rnor_5.01711,788,527 - 11,802,863 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006253657   ⟹   XP_006253719
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2179,150,609 - 9,164,982 (+)NCBI
Rnor_6.0179,679,512 - 9,693,878 (+)NCBI
Rnor_5.01711,788,527 - 11,802,863 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008771507   ⟹   XP_008769729
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2179,152,055 - 9,164,979 (+)NCBI
Rnor_6.0179,680,227 - 9,693,878 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_112286   ⟸   NM_031024
- UniProtKB: Q07266 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006253717   ⟸   XM_006253655
- Peptide Label: isoform X1
- UniProtKB: A0A0H2UHL9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253718   ⟸   XM_006253656
- Peptide Label: isoform X2
- UniProtKB: C6L8E0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253719   ⟸   XM_006253657
- Peptide Label: isoform X3
- UniProtKB: Q07266 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008769729   ⟸   XM_008771507
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000019569   ⟸   ENSRNOT00000019569
RefSeq Acc Id: ENSRNOP00000019393   ⟸   ENSRNOT00000019393
Protein Domains
ADF-H

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700305
Promoter ID:EPDNEW_R10827
Type:initiation region
Name:Dbn1_1
Description:drebrin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0179,679,552 - 9,679,612EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70885 AgrOrtholog
Ensembl Genes ENSRNOG00000014170 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000019393 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000019569 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019393 UniProtKB/Swiss-Prot
  ENSRNOT00000019569 UniProtKB/TrEMBL
Gene3D-CATH 3.40.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8368018 IMAGE-MGC_LOAD
InterPro ADF-H UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADF-H/Gelsolin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Drebrin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81653 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156631 IMAGE-MGC_LOAD
NCBI Gene 81653 ENTREZGENE
PANTHER PTHR10829:SF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cofilin_ADF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dbn1 PhenoGen
PROSITE ADF_H UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ADF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0H2UHL9 ENTREZGENE, UniProtKB/TrEMBL
  C6L8E0 ENTREZGENE, UniProtKB/TrEMBL
  DREB_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A5D6R1 UniProtKB/Swiss-Prot
  O70205 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Dbn1  drebrin 1      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization present at submembraneous regions 70708
gene_expression expressed in dendrites of the adult brain 70708