Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Acat2 (acetyl-CoA acetyltransferase 2) Rattus norvegicus
Analyze
Symbol: Acat2
Name: acetyl-CoA acetyltransferase 2
Description: Exhibits acetyl-CoA C-acetyltransferase activity. Involved in several processes, including animal organ development; bile acid signaling pathway; and ketone body catabolic process. Localizes to cytosol. Biomarker of premature menopause. Human ortholog(s) of this gene implicated in coronary artery disease. Orthologous to human ACAT2 (acetyl-CoA acetyltransferase 2); PARTICIPATES IN bile acid signaling pathway; alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ab2-076; Acat3; acetyl-CoA acetyltransferase, cytosolic; acetyl-Coenzyme A acetyltransferase 2; acetyl-Coenzyme A acetyltransferase 3; cytosolic acetoacetyl-CoA thiolase; MGC95138; similar to acetyl CoA transferase-like
Orthologs:
Homo sapiens (human) : ACAT2 (acetyl-CoA acetyltransferase 2)  HGNC  Alliance
Mus musculus (house mouse) : Acat2 (acetyl-Coenzyme A acetyltransferase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acat2 (acetyl-CoA acetyltransferase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ACAT2 (acetyl-CoA acetyltransferase 2)
Canis lupus familiaris (dog) : ACAT2 (acetyl-CoA acetyltransferase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acat2 (acetyl-CoA acetyltransferase 2)
Sus scrofa (pig) : ACAT2 (acetyl-CoA acetyltransferase 2)
Chlorocebus sabaeus (African green monkey) : ACAT2 (acetyl-CoA acetyltransferase 2)
Heterocephalus glaber (naked mole-rat) : Acat2 (acetyl-CoA acetyltransferase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0147,972,399 - 47,992,654 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,972,399 - 47,992,653 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,757,961 - 51,776,935 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,922,020 - 41,940,074 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1141,924,964 - 41,943,018 (+)NCBI
Celera143,380,977 - 43,399,019 (+)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Acat2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359366
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2020-07-07
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.