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Gene: Acat2 (acetyl-Coenzyme A acetyltransferase 2) Mus musculus
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Symbol: Acat2
Name: acetyl-Coenzyme A acetyltransferase 2
Description: Predicted to have acetyl-CoA C-acetyltransferase activity. Involved in positive regulation of intestinal cholesterol absorption. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in coronary artery disease. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human ACAT2 (acetyl-CoA acetyltransferase 2); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: acetyl-CoA acetyltransferase, cytosolic; AW742799; cytosolic acetoacetyl-CoA thiolase; t-complex protein 1, related sequence 1; Tcp-1x; Tcp1-rs1
Orthologs:
Homo sapiens (human) : ACAT2 (acetyl-CoA acetyltransferase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Acat2 (acetyl-CoA acetyltransferase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acat2 (acetyl-CoA acetyltransferase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ACAT2 (acetyl-CoA acetyltransferase 2)
Canis lupus familiaris (dog) : ACAT2 (acetyl-CoA acetyltransferase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acat2 (acetyl-CoA acetyltransferase 2)
Sus scrofa (pig) : ACAT2 (acetyl-CoA acetyltransferase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381712,943,042 - 12,960,725 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371713,135,908 - 13,153,591 (-)NCBIGRCm37mm9NCBIm37
MGSCv361712,785,822 - 12,803,643 (-)NCBImm8
Celera1712,974,572 - 12,992,259 (-)NCBICelera
Cytogenetic Map17 A1NCBI
cM Map178.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Acat2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552173
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.