Gene: Adipor2 (adiponectin receptor 2) Rattus norvegicus
Analyze
Symbol:
Adipor2
Name:
adiponectin receptor 2
Description:
Predicted to have adipokinetic hormone receptor activity; adiponectin binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of hepatic stellate cell migration; positive regulation of glucose import; and response to fructose. Predicted to localize to intrinsic component of plasma membrane. Biomarker of end stage renal disease; fatty liver disease (multiple); glucose metabolism disease (multiple); and obesity. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease and type 2 diabetes mellitus. Orthologous to human ADIPOR2 (adiponectin receptor 2); PARTICIPATES IN adiponectin signaling pathway; INTERACTS WITH (S)-nicotine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
adiponectin receptor protein 2; LOC312670
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ADIPOR2 (adiponectin receptor 2) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Adipor2 (adiponectin receptor 2) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Adipor2 (adiponectin receptor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ADIPOR2 (adiponectin receptor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ADIPOR2 (adiponectin receptor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Adipor2 (adiponectin receptor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ADIPOR2 (adiponectin receptor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
ADIPOR2 (adiponectin receptor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Adipor2 (adiponectin receptor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
ADIPOR2 (adiponectin receptor 2)
Alliance
DIOPT (PANTHER|HGNC|Ensembl Compara|OMA|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam)
Mus musculus (house mouse):
Adipor2 (adiponectin receptor 2)
Alliance
DIOPT (PANTHER|Ensembl Compara|OMA|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam)
Danio rerio (zebrafish):
adipor2 (adiponectin receptor 2)
Alliance
DIOPT (PANTHER|Ensembl Compara|OMA|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam)
Drosophila melanogaster (fruit fly):
AdipoR
Alliance
DIOPT (PANTHER|OMA|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam)
Saccharomyces cerevisiae (baker's yeast):
IZH1
Alliance
DIOPT (PANTHER|OMA|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam)
Saccharomyces cerevisiae (baker's yeast):
IZH2
Alliance
DIOPT (PANTHER|OMA|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid|TreeFam)
Caenorhabditis elegans (roundworm):
paqr-1
Alliance
DIOPT (PANTHER|OMA|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid)
Caenorhabditis elegans (roundworm):
paqr-2
Alliance
DIOPT (PANTHER|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid)
Saccharomyces cerevisiae (baker's yeast):
IZH4
Alliance
DIOPT (PANTHER|PhylomeDB|OrthoFinder)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 4 151,412,135 - 151,480,108 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 4 151,414,684 - 151,428,894 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 4 217,327,044 - 217,392,865 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 4 155,664,035 - 155,677,627 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 4 155,907,605 - 155,942,117 (-) NCBI Celera 4 141,389,717 - 141,403,635 (-) NCBI Celera Cytogenetic Map 4 q42 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
RGD Manual Annotations
Alcoholic Fatty Liver treatment ISO RGD:1317350 25824939 ; 25440493 ; 25824943 RGD Alcoholic Fatty Liver treatment IEP 25330099 RGD Alcoholic Liver Diseases treatment IEP 25824940 RGD breast cancer no_association ISO RGD:1317349 8694417 RGD Chemical and Drug Induced Liver Injury severity IEP 8695926 associated with obesity, LPS, mRNA:decreased expression:liver (rat) RGD Diabetes Mellitus, Experimental no_association IDA 2312495 RGD Diabetes Mellitus, Experimental IDA 2312478 RGD Diabetes Mellitus, Experimental ISO RGD:1317350 2312488 RGD end stage renal disease IEP 8695941 RGD Endotoxemia severity IEP 8695926 associated with obesity, mRNA:decreased expression:liver (rat) RGD Experimental Liver Cirrhosis severity ISO RGD:1317350 24922203 RGD fatty liver disease treatment IEP 2307264 associated with Diabetes Mellitus, Experimental RGD fatty liver disease treatment IEP 21406435 RGD Fetal Growth Retardation treatment IEP 8695947 RGD glucose intolerance treatment IEP 25330096 RGD hyperinsulinism IEP 1625765 mRNA:increased expression:skeletal muscle cell RGD Insulin Resistance treatment IEP 25824940 ; 21406435 RGD liver cirrhosis ISO RGD:1317350 1599139 mRNA:decreased expression:liver (mouse) RGD myocardial infarction ISO RGD:1317350 1625764 mRNA, protein:decreased expression:heart left ventricle RGD non-alcoholic fatty liver disease treatment IEP 25824941 ; 25330097 RGD non-alcoholic fatty liver disease severity ISO RGD:1317349 25440492 mRNA:increased expression:liver (human) RGD non-alcoholic fatty liver disease IEP 1599139 mRNA:increased expression:liver (rat) RGD non-alcoholic fatty liver disease susceptibility ISO RGD:1317350 24922201 mRNA, protein:decreased expression:serum, liver (mouse) RGD non-alcoholic fatty liver disease susceptibility ISO RGD:1317349 24922200 DNA:missense mutation:cds: (human) RGD non-alcoholic steatohepatitis treatment IEP 25824942 associated with obesity RGD non-alcoholic steatohepatitis treatment ISO RGD:1317350 25330095 RGD non-alcoholic steatohepatitis ISO RGD:1317350 25330094 associated with obesity, protein:decreased expression:liver (mouse) RGD non-alcoholic steatohepatitis susceptibility IEP 21076282 mRNA:decreased expression:liver (rat) RGD non-alcoholic steatohepatitis treatment IEP 25440494 RGD obesity IEP 1625763 mRNA:increased expression:liver RGD obesity treatment IEP 21406435 RGD obesity severity IEP 8695926 mRNA:decreased expression:liver (rat) RGD obesity treatment IEP 25824942 associated with non-alcoholic fatty liver disease RGD type 2 diabetes mellitus ISO RGD:1317349 2312490 ; 2312480 ; 2312486 RGD type 2 diabetes mellitus no_association ISO RGD:1317349 2312476 RGD
Imported Annotations - ClinVar
Hyperphosphatemic Familial Tumoral Calcinosis 1 ISO RGD:1317349 8554872 ClinVar Annotator: match by term: Hyperphosphatemic familial tumoral calcinosis 1 ClinVar PMID:25378588 , PMID:29389098
Imported Annotations - CTD
Female Infertility ISO RGD:1317349 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:22265003
(+)-catechin multiple interactions ISO RGD:1317349 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of ADIPOR2 mRNA CTD PMID:24763279 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of ADIPOR2 mRNA CTD PMID:22265867 1,2-dichloroethane decreases expression ISO RGD:1317350 6480464 ethylene dichloride results in decreased expression of ADIPOR2 mRNA CTD PMID:28189721 , PMID:28960355 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of ADIPOR2 mRNA CTD PMID:30723492 17alpha-ethynylestradiol multiple interactions ISO RGD:1317350 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ADIPOR2 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO RGD:1317349 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ADIPOR2 mRNA, [Progesterone co-treated with Estradiol] results in increased expression of ADIPOR2 mRNA CTD PMID:17404688 , PMID:19619570 17beta-estradiol decreases expression ISO RGD:1317349 6480464 Estradiol results in decreased expression of ADIPOR2 mRNA CTD PMID:19619570 , PMID:21185374 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1317349 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ADIPOR2 mRNA CTD PMID:19619570 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ADIPOR2 mRNA CTD PMID:26232522 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1317350 6480464 Tetrachlorodibenzodioxin affects the expression of ADIPOR2 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1317350 6480464 Tetrachlorodibenzodioxin results in increased expression of ADIPOR2 mRNA CTD PMID:20159946 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1317350 6480464 Tetrachlorodibenzodioxin results in decreased expression of ADIPOR2 mRNA CTD PMID:16214954 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1317349 6480464 Tetrachlorodibenzodioxin results in decreased expression of ADIPOR2 mRNA CTD PMID:19619570 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1317350 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ADIPOR2 mRNA CTD PMID:17942748 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of ADIPOR2 mRNA CTD PMID:21346803 2-methoxyethanol increases expression EXP 6480464 methyl cellosolve results in increased expression of ADIPOR2 mRNA CTD PMID:21061450 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:20959002 3-aminobenzamide increases expression EXP 6480464 3-aminobenzamide results in increased expression of ADIPOR2 mRNA CTD PMID:18815186 3-aminobenzamide increases expression ISO RGD:1317350 6480464 3-aminobenzamide results in increased expression of ADIPOR2 mRNA CTD PMID:18815186 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1317350 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ADIPOR2 mRNA CTD PMID:23428407 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of ADIPOR2 mRNA CTD PMID:30723492 9-cis,11-trans-octadecadienoic acid multiple interactions EXP 6480464 [trans-10, cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in increased expression of ADIPOR2 mRNA CTD PMID:17408517 acetaldehyde multiple interactions ISO RGD:1317350 6480464 Acetaldehyde inhibits the reaction [LEP protein results in increased expression of ADIPOR2 protein] CTD PMID:17949463 acetaldehyde increases expression ISO RGD:1317350 6480464 Acetaldehyde results in increased expression of ADIPOR2 protein CTD PMID:17949463 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of ADIPOR2 mRNA CTD PMID:31881176 aflatoxin B1 increases methylation ISO RGD:1317349 6480464 Aflatoxin B1 results in increased methylation of ADIPOR2 gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO RGD:1317349 6480464 Aflatoxin B1 results in decreased expression of ADIPOR2 mRNA CTD PMID:27153756 aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of ADIPOR2 protein CTD PMID:21912612 aldehydo-D-glucose multiple interactions EXP 6480464 ADIPOQ protein inhibits the reaction [Glucose results in decreased expression of ADIPOR2 protein] CTD PMID:21912612 allopurinol multiple interactions EXP 6480464 Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]] CTD PMID:21912612 arsane affects methylation ISO RGD:1317349 6480464 Arsenic affects the methylation of ADIPOR2 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:1317349 6480464 Arsenic affects the methylation of ADIPOR2 gene CTD PMID:25304211 Aurothioglucose multiple interactions ISO RGD:1317350 6480464 [Dietary Fats co-treated with Aurothioglucose] results in decreased expression of ADIPOR2 protein CTD PMID:21382165 benzo[a]pyrene increases expression ISO RGD:1317350 6480464 Benzo(a)pyrene results in increased expression of ADIPOR2 mRNA CTD PMID:21964900 benzo[a]pyrene decreases expression ISO RGD:1317350 6480464 Benzo(a)pyrene results in decreased expression of ADIPOR2 mRNA CTD PMID:23735875 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1317349 6480464 7 more ... CTD PMID:19150397 bezafibrate increases expression ISO RGD:1317350 6480464 Bezafibrate results in increased expression of ADIPOR2 mRNA CTD PMID:16574099 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ADIPOR2 mRNA, bisphenol A results in decreased expression of ADIPOR2 protein CTD PMID:24472609 , PMID:28657538 bisphenol A decreases expression ISO RGD:1317350 6480464 bisphenol A results in decreased expression of ADIPOR2 mRNA CTD PMID:29161229 bisphenol A decreases methylation ISO RGD:1317350 6480464 bisphenol A results in decreased methylation of ADIPOR2 promoter CTD PMID:27312807 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ADIPOR2 mRNA CTD PMID:25181051 , PMID:30816183 buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of ADIPOR2 mRNA CTD PMID:24136188 caffeine increases expression EXP 6480464 Caffeine results in increased expression of ADIPOR2 mRNA CTD PMID:22583948 choline multiple interactions ISO RGD:1317350 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ADIPOR2 mRNA CTD PMID:20938992 conjugated linoleic acid decreases expression ISO RGD:1317350 6480464 Linoleic Acids, Conjugated results in decreased expression of ADIPOR2 mRNA CTD PMID:17322064 conjugated linoleic acid multiple interactions ISO RGD:1317350 6480464 rosiglitazone inhibits the reaction [Linoleic Acids, Conjugated results in decreased expression of ADIPOR2 mRNA] CTD PMID:17322064 copper atom increases expression EXP 6480464 Copper results in increased expression of ADIPOR2 mRNA CTD PMID:30556269 copper(0) increases expression EXP 6480464 Copper results in increased expression of ADIPOR2 mRNA CTD PMID:30556269 copper(II) sulfate increases expression ISO RGD:1317349 6480464 Copper Sulfate results in increased expression of ADIPOR2 mRNA CTD PMID:19549813 cysteamine increases expression EXP 21079417 dietary cysteamine increases expression of adipor2 mRNA in soleus muscle and retroperitoneal adipose tissue RGD D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of ADIPOR2 protein CTD PMID:21912612 D-glucose multiple interactions EXP 6480464 ADIPOQ protein inhibits the reaction [Glucose results in decreased expression of ADIPOR2 protein] CTD PMID:21912612 dexamethasone multiple interactions ISO RGD:1317349 6480464 Dexamethasone promotes the reaction [rosiglitazone results in increased activity of ADIPOR2 promoter] CTD PMID:16609881 dexamethasone multiple interactions ISO RGD:1317350 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ADIPOR2 mRNA CTD PMID:23428407 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of ADIPOR2 mRNA CTD PMID:21266533 diuron decreases expression EXP 6480464 Diuron results in decreased expression of ADIPOR2 mRNA CTD PMID:25152437 ethanol decreases expression ISO RGD:1317350 25824943 ethanol decreases expression of Adipor2 mRNA in liver RGD ethanol affects expression ISO RGD:1317350 6480464 Ethanol affects the expression of ADIPOR2 mRNA CTD PMID:30319688 ethanol decreases expression ISO RGD:1317350 25440493 ethanol feeding decreases expression of adipor2 mRNA in mouse liver RGD ethanol multiple interactions EXP 6480464 Scopoletin inhibits the reaction [Ethanol results in decreased expression of ADIPOR2 mRNA] more ... CTD PMID:26115886 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of ADIPOR2 mRNA, Ethanol results in decreased expression of ADIPOR2 protein CTD PMID:26115886 ethanol decreases expression ISO RGD:1317350 25824939 ethanol feeding decreases expression of Adipor2 in liver RGD ethanol decreases expression ISO RGD:1317350 6480464 Ethanol results in decreased expression of ADIPOR2 mRNA CTD PMID:18755807 , PMID:20007851 ethanol multiple interactions ISO RGD:1317350 6480464 [rosiglitazone co-treated with Ethanol] results in increased expression of ADIPOR2 mRNA CTD PMID:20007851 ethanol decreases expression EXP 25824940 ethanol decreases expression of Adipor2 mRNA in liver RGD fenofibrate increases expression ISO RGD:1317350 6480464 Fenofibrate results in increased expression of ADIPOR2 mRNA CTD PMID:16306350 finasteride increases expression EXP 6480464 Finasteride results in increased expression of ADIPOR2 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:1317350 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ADIPOR2 mRNA CTD PMID:20938992 fosinopril increases expression EXP 2307264 fosinopril increases expression of adipor2 mRNA in rat liver RGD fructose decreases expression ISO RGD:1317350 6480464 Fructose results in decreased expression of ADIPOR2 protein CTD PMID:28257781 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of ADIPOR2 mRNA CTD PMID:24136188 glucose decreases expression EXP 6480464 Glucose results in decreased expression of ADIPOR2 protein CTD PMID:21912612 glucose multiple interactions EXP 6480464 ADIPOQ protein inhibits the reaction [Glucose results in decreased expression of ADIPOR2 protein] CTD PMID:21912612 gold atom multiple interactions ISO RGD:1317350 6480464 [Gold co-treated with Polyethylene Glycols] results in decreased expression of ADIPOR2 mRNA CTD PMID:19695318 gold(0) multiple interactions ISO RGD:1317350 6480464 [Gold co-treated with Polyethylene Glycols] results in decreased expression of ADIPOR2 mRNA CTD PMID:19695318 hexadecanoic acid increases expression EXP 24922202 palmitic acid cotreated with ethanol increases expression of adipor2 mRNA in rat primary hepatocytes RGD hexadecanoic acid decreases expression ISO RGD:1317349 24922201 palmitic acid decreases expression of ADIPOR2 mRNA and protein in hepatocellular carcinoma cells RGD isoflavones decreases expression EXP 6480464 Isoflavones results in decreased expression of ADIPOR2 protein CTD PMID:22155228 L-methionine multiple interactions ISO RGD:1317350 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ADIPOR2 mRNA CTD PMID:20938992 lead diacetate increases expression ISO RGD:1317350 6480464 lead acetate results in increased expression of ADIPOR2 mRNA CTD PMID:21829687 leflunomide decreases expression ISO RGD:1317349 6480464 leflunomide results in decreased expression of ADIPOR2 mRNA CTD PMID:28988120 lipopolysaccharide multiple interactions ISO RGD:1317350 6480464 ADIPOR2 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]], ADIPOR2 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]] CTD PMID:20861358 lipopolysaccharide decreases expression EXP 8695926 lipopolysaccharide decreases expression of adipor2 mRNA in obese rat liver RGD metformin increases expression EXP 25824940 metformin increases expression of Adipor2 mRNA in liver RGD methotrexate increases expression ISO RGD:1317349 6480464 Methotrexate results in increased expression of ADIPOR2 mRNA CTD PMID:17400583 mifepristone multiple interactions ISO RGD:1317349 6480464 Mifepristone inhibits the reaction [rosiglitazone results in increased activity of ADIPOR2 promoter] CTD PMID:16609881 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein], Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]] CTD PMID:21912612 nicotine increases expression EXP 6480464 Nicotine results in increased expression of ADIPOR2 mRNA CTD PMID:22265867 nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of ADIPOR2 mRNA CTD PMID:24136188 oleic acid decreases expression EXP 24922202 oleic acid cotreated with ethanol decreases expression of adipor2 mRNA in rat primary hepatocytes RGD paraquat multiple interactions ISO RGD:1317349 6480464 ADIPOR1 protein inhibits the reaction [Paraquat results in increased expression of ADIPOR2 mRNA], ADIPOR1 protein inhibits the reaction [Paraquat results in increased expression of ADIPOR2 protein] CTD PMID:25945502 paraquat increases expression ISO RGD:1317349 6480464 Paraquat results in increased expression of ADIPOR2 mRNA, Paraquat results in increased expression of ADIPOR2 protein CTD PMID:25945502 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of ADIPOR2 mRNA CTD PMID:19162173 perfluorooctanoic acid increases expression ISO RGD:1317350 6480464 perfluorooctanoic acid results in increased expression of ADIPOR2 mRNA CTD PMID:17681415 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of ADIPOR2 mRNA CTD PMID:19162173 pirinixic acid multiple interactions ISO RGD:1317350 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ADIPOR2 mRNA CTD PMID:19710929 pirinixic acid increases expression ISO RGD:1317350 6480464 pirinixic acid results in increased expression of ADIPOR2 mRNA CTD PMID:16306350 , PMID:18301758 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of ADIPOR2 mRNA CTD PMID:19162173 piroxicam decreases expression ISO RGD:1317349 6480464 Piroxicam results in decreased expression of ADIPOR2 mRNA CTD PMID:21858171 progesterone multiple interactions ISO RGD:1317349 6480464 [Progesterone co-treated with Estradiol] results in increased expression of ADIPOR2 mRNA CTD PMID:17404688 progesterone increases expression ISO RGD:1317349 6480464 Progesterone results in increased expression of ADIPOR2 mRNA CTD PMID:17404688 , PMID:29603059 propiconazole decreases expression ISO RGD:1317350 6480464 propiconazole results in decreased expression of ADIPOR2 mRNA CTD PMID:21278054 resveratrol increases expression ISO RGD:1317350 25824943 resveratrol increases expression of Adipor2 mRNA in liver RGD resveratrol increases expression ISO RGD:1317350 6480464 resveratrol results in increased expression of ADIPOR2 mRNA CTD PMID:18755807 rosiglitazone affects expression EXP 25440494 rosiglitazone affects expression of adipor2 mRNA and protein in NASH (rat) liver, visceral fat, and skeletal muscle RGD rosiglitazone increases expression EXP 21406435 rosiglitazone increases expression of adipor2 protein in liver of OLETF rats RGD rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of ADIPOR2 mRNA CTD PMID:28374803 scopoletin multiple interactions EXP 6480464 Scopoletin inhibits the reaction [Ethanol results in decreased expression of ADIPOR2 mRNA], Scopoletin inhibits the reaction [Ethanol results in decreased expression of ADIPOR2 protein] CTD PMID:26115886 scopoletin increases expression EXP 25330099 scopoletin increases expression of adipor2 mRNA and protein in epididymal white adipose tissue of alcohol fed rats RGD silibinin increases expression EXP 25330099 silymarin (silibinin) increases expression of adipor2 mRNA and protein in epididymal white adipose tissue of alcohol fed rats RGD silicon dioxide decreases expression ISO RGD:1317350 6480464 Silicon Dioxide results in decreased expression of ADIPOR2 mRNA CTD PMID:23221170 streptozocin multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein], Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]] CTD PMID:21912612 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of ADIPOR2 protein CTD PMID:21912612 sulindac multiple interactions EXP 6480464 [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ADIPOR2 mRNA CTD PMID:20371263 tert-butyl hydroperoxide decreases expression ISO RGD:1317349 6480464 tert-Butylhydroperoxide results in decreased expression of ADIPOR2 mRNA CTD PMID:15336504 Tesaglitazar increases expression EXP 6480464 tesaglitazar results in increased expression of ADIPOR2 mRNA CTD PMID:21515302 tetracycline increases expression ISO RGD:1317350 6480464 Tetracycline results in increased expression of ADIPOR2 mRNA CTD PMID:16917069 titanium dioxide increases expression ISO RGD:1317350 6480464 titanium dioxide results in increased expression of ADIPOR2 mRNA CTD PMID:23409001 , PMID:29264374 titanium dioxide decreases expression ISO RGD:1317350 6480464 titanium dioxide results in decreased expression of ADIPOR2 mRNA CTD PMID:23557971 tributylstannane increases expression ISO RGD:1317350 6480464 tributyltin results in increased expression of ADIPOR2 mRNA CTD PMID:23428407 trichostatin A affects expression ISO RGD:1317349 6480464 trichostatin A affects the expression of ADIPOR2 mRNA CTD PMID:28542535 trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of ADIPOR2 mRNA CTD PMID:24136188 urethane increases expression ISO RGD:1317349 6480464 Urethane results in increased expression of ADIPOR2 mRNA CTD PMID:28818685 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of ADIPOR2 mRNA CTD PMID:24136188 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of ADIPOR2 mRNA CTD PMID:23869203 zinc atom multiple interactions ISO RGD:1317349 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of ADIPOR2 mRNA CTD PMID:18593933 zinc(0) multiple interactions ISO RGD:1317349 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of ADIPOR2 mRNA CTD PMID:18593933
Gene-Chemical Interaction Annotations
