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Gene: Cd36 (CD36 molecule) Rattus norvegicus
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Symbol: Cd36
Name: CD36 molecule
Description: Exhibits several functions, including oleic acid binding activity; scavenger receptor activity; and thrombospondin receptor activity. Involved in several processes, including fatty acid metabolic process; positive regulation of transport; and response to peptide hormone. Localizes to several cellular components, including the brush border membrane; caveola; and sarcolemma. Used to study interstitial lung disease (multiple); macular degeneration; myocardial infarction; obesity; and polycystic ovary syndrome. Biomarker of artery disease (multiple); hypertrophic cardiomyopathy; nephrosis; obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including hemolytic-uremic syndrome; osteoarthritis; pemphigus; platelet-type bleeding disorder 10; and type 2 diabetes mellitus. Orthologous to human CD36 (CD36 molecule); PARTICIPATES IN retinol metabolic pathway; cell-extracellular matrix signaling pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; INTERACTS WITH (+)-alpha-tocopherol; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adipocyte membrane protein; CD36 antigen; CD36 antigen (collagen type I receptor, thrombospondin receptor); Cd36 antigen-like; CD36 molecule (thrombospondin receptor); collagen type I receptor thrombospondin receptor; Fat; fatty acid translocase; fatty acid transport protein; glycoprotein IIIb; GPIIIB; GPIV; LOC499984; MGC108510; MGC91634; PAS IV; PAS-4; platelet glycoprotein 4; platelet glycoprotein IV; RGD1562323; similar to fatty acid translocase/CD36
Orthologs:
Homo sapiens (human) : CD36 (CD36 molecule)  HGNC  Alliance
Mus musculus (house mouse) : Cd36 (CD36 molecule)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd36 (CD36 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD36 (CD36 molecule)
Canis lupus familiaris (dog) : CD36 (CD36 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd36 (CD36 molecule)
Sus scrofa (pig) : CD36 (CD36 molecule)
more info ...
Is Marker For: Strains:   BN   SHR   WKY   BN.SHR-(Il6-Cd36)/Cub   SHR-Tg(Ef1a-Cd36)10Ipcv   SHR-Tg(Ef1a-Cd36)19Ipcv   SHR-Tg(Ef1a-Cd36)93Ipcv   SHR-Tg(Ef1a-Cd36)106Ipcv   SHR/4Dmcr   SHRSP/3Dmcr   SHR/2Dmcr   SHR/3Dmcr   SHRSP/4Dmcr   SHRSP/5Dmcr   SHRSP/2Dmcr  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0414,150,309 - 14,191,498 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl414,001,761 - 14,249,749 (+)Ensembl
Rnor_5.0414,125,297 - 14,166,434 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4413,534,582 - 13,554,416 (+)NCBIRGSC3.4rn4RGSC3.4
Celera412,880,238 - 12,941,086 (+)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cd36
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 2301
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.