Cd36 (CD36 molecule) - Rat Genome Database

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Gene: Cd36 (CD36 molecule) Ictidomys tridecemlineatus
Analyze
Symbol: Cd36
Name: CD36 molecule
RGD ID: 12548073
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); high-density lipoprotein particle binding (ortholog); lipid binding (ortholog); INVOLVED IN amyloid fibril formation (ortholog); amyloid-beta clearance by cellular catabolic process (ortholog); apoptotic cell clearance (ortholog); PARTICIPATES IN retinol metabolic pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); Alcoholic Fatty Liver (ortholog); allergic contact dermatitis (ortholog); FOUND IN apical part of cell (ortholog); brush border membrane (ortholog); caveola (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: platelet glycoprotein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511862,188,852 - 62,269,004 (+)NCBI
SpeTri2.0NW_004936810791,823 - 838,303 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Lung Injury  (ISO)
Alcoholic Fatty Liver  (ISO)
allergic contact dermatitis  (ISO)
Alzheimer's disease  (ISO)
arteriosclerosis  (ISO)
atherosclerosis  (ISO)
atrial fibrillation  (ISO)
blood platelet disease  (ISO)
brain ischemia  (ISO)
Cardiac Arrhythmias  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
celiac disease  (ISO)
Cerebral Hemorrhage  (ISO)
cerebral infarction  (ISO)
cerebral malaria  (ISO)
chronic myeloid leukemia  (ISO)
colitis  (ISO)
corneal neovascularization  (ISO)
Coronary Disease  (ISO)
dermatomyositis  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (ISO)
dilated cardiomyopathy  (ISO)
endometriosis  (ISO)
epilepsy  (ISO)
essential thrombocythemia  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
fatty liver disease  (ISO)
glucose intolerance  (ISO)
granulomatosis with polyangiitis  (ISO)
Hematoma  (ISO)
hemolytic-uremic syndrome  (ISO)
Hypercholesterolemia  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
inclusion body myositis  (ISO)
Inflammation  (ISO)
Insulin Resistance  (ISO)
Knee Osteoarthritis  (ISO)
liver cirrhosis  (ISO)
macular degeneration  (ISO)
malaria  (ISO)
Metabolic Syndrome  (ISO)
middle cerebral artery infarction  (ISO)
Mycobacterium Infections  (ISO)
myeloid neoplasm  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
nephrosis  (ISO)
non-alcoholic fatty liver disease  (ISO)
obesity  (ISO)
osteoarthritis  (ISO)
pemphigus  (ISO)
platelet-type bleeding disorder 10  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
polycystic ovary syndrome  (ISO)
polycythemia vera  (ISO)
primary immunodeficiency disease  (ISO)
pulmonary fibrosis  (ISO)
pulmonary tuberculosis  (ISO)
relapsing-remitting multiple sclerosis  (ISO)
Reperfusion Injury  (ISO)
Retroperitoneal Fibrosis  (ISO)
rheumatic heart disease  (ISO)
Sepsis  (ISO)
sickle cell anemia  (ISO)
silicosis  (ISO)
Staphylococcal Infections  (ISO)
Tachycardia  (ISO)
thrombotic thrombocytopenic purpura  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
visual epilepsy  (ISO)
Weight Gain  (ISO)
Wounds, Penetrating  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
amyloid fibril formation  (ISO)
amyloid-beta clearance by cellular catabolic process  (ISO)
apoptotic cell clearance  (ISO)
cell surface receptor signaling pathway  (ISO)
cell-cell adhesion via plasma-membrane adhesion molecules  (ISO)
cellular response to amyloid-beta  (ISO)
cellular response to bacterial lipopeptide  (ISO)
cellular response to diacyl bacterial lipopeptide  (ISO)
cellular response to hydroperoxide  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to lipoteichoic acid  (ISO)
cellular response to low-density lipoprotein particle stimulus  (ISO)
cellular response to oxidised low-density lipoprotein particle stimulus  (ISO)
cGMP-mediated signaling  (ISO)
cholesterol import  (ISO)
cholesterol transport  (ISO)
defense response to Gram-positive bacterium  (ISO)
digestive tract development  (ISO)
eating behavior  (ISO)
energy homeostasis  (ISO)
fatty acid metabolic process  (ISO)
fatty acid oxidation  (ISO)
fatty acid transport  (ISO)
glucose homeostasis  (ISO)
intestinal absorption  (ISO)
intestinal cholesterol absorption  (ISO)
lipid storage  (ISO)
lipid transport across blood-brain barrier  (ISO)
lipoprotein transport  (ISO)
long-chain fatty acid import across plasma membrane  (ISO)
long-chain fatty acid import into cell  (ISO)
long-chain fatty acid metabolic process  (ISO)
long-chain fatty acid transport  (ISO)
low-density lipoprotein particle clearance  (ISO)
low-density lipoprotein particle mediated signaling  (ISO)
maternal placenta development  (ISO)
negative regulation of angiogenesis  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of protein import into nucleus  (ISO)
negative regulation of systemic arterial blood pressure  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
nitric oxide mediated signal transduction  (ISO)
oxidised low-density lipoprotein particle clearance  (ISO)
phagocytosis, recognition  (ISO)
plasma lipoprotein particle clearance  (ISO)
positive regulation of blood coagulation  (ISO)
positive regulation of blood microparticle formation  (ISO)
positive regulation of cell death  (ISO)
positive regulation of cell-matrix adhesion  (ISO)
positive regulation of cholesterol storage  (ISO)
positive regulation of cold-induced thermogenesis  (ISO)
positive regulation of cytokine production  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of glycogen biosynthetic process  (ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
positive regulation of interleukin-1 beta production  (ISO)
positive regulation of interleukin-12 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of macrophage cytokine production  (ISO)
positive regulation of macrophage derived foam cell differentiation  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of nitric oxide biosynthetic process  (ISO)
positive regulation of NLRP3 inflammasome complex assembly  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of phagocytosis  (ISO)
positive regulation of phagocytosis, engulfment  (ISO)
positive regulation of reactive oxygen species biosynthetic process  (ISO)
positive regulation of reactive oxygen species metabolic process  (ISO)
positive regulation of triglyceride metabolic process  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
receptor internalization  (ISO)
receptor-mediated endocytosis  (ISO)
regulation of action potential  (ISO)
regulation of protein-containing complex assembly  (ISO)
regulation of removal of superoxide radicals  (ISO)
regulation of toll-like receptor signaling pathway  (ISO)
response to activity  (ISO)
response to bacterium  (ISO)
response to drug  (ISO)
response to estradiol  (ISO)
response to fatty acid  (ISO)
response to growth hormone  (ISO)
response to linoleic acid  (ISO)
response to lipid  (ISO)
response to mechanical stimulus  (ISO)
response to nutrient  (ISO)
response to stilbenoid  (ISO)
sensory perception of taste  (ISO)
short-chain fatty acid transport  (ISO)
triglyceride metabolic process  (ISO)
triglyceride transport  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Cd36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511862,188,852 - 62,269,004 (+)NCBI
SpeTri2.0NW_004936810791,823 - 838,303 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl780,369,575 - 80,679,277 (+)EnsemblGRCh38hg38GRCh38
GRCh38780,602,207 - 80,679,277 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37780,231,523 - 80,308,593 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36780,069,459 - 80,144,262 (+)NCBINCBI36hg18NCBI36
Build 34779,912,607 - 79,950,974NCBI
Celera774,932,098 - 75,009,206 (+)NCBI
Cytogenetic Map7q21.11NCBI
HuRef774,834,319 - 74,911,371 (+)NCBIHuRef
CHM1_1780,162,020 - 80,239,042 (+)NCBICHM1_1
CRA_TCAGchr7v2779,562,929 - 79,640,010 (+)NCBI
Cd36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39517,986,688 - 18,093,957 (-)NCBIGRCm39mm39
GRCm39 Ensembl517,986,688 - 18,093,799 (-)Ensembl
GRCm38517,781,690 - 17,888,959 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl517,781,690 - 17,888,801 (-)EnsemblGRCm38mm10GRCm38
MGSCv37517,287,508 - 17,394,777 (-)NCBIGRCm37mm9NCBIm37
MGSCv36517,293,840 - 17,347,520 (-)NCBImm8
Celera514,757,802 - 14,864,361 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map58.11NCBI
Cd36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2417,317,343 - 17,410,084 (+)NCBI
Rnor_6.0 Ensembl414,001,761 - 14,249,749 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0414,150,309 - 14,191,498 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0414,125,297 - 14,166,434 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4413,534,582 - 13,554,416 (+)NCBIRGSC3.4rn4RGSC3.4
Celera412,880,238 - 12,941,086 (+)NCBICelera
Cytogenetic Map4q11NCBI
Cd36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554105,003,668 - 5,075,313 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554105,003,720 - 5,120,903 (-)NCBIChiLan1.0ChiLan1.0
CD36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1786,228,856 - 86,305,865 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl786,265,114 - 86,305,865 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0772,566,478 - 72,643,517 (+)NCBIMhudiblu_PPA_v0panPan3
CD36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11820,299,808 - 20,375,856 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1820,339,050 - 20,372,639 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1820,015,595 - 20,045,069 (+)NCBI
ROS_Cfam_1.01820,745,564 - 20,821,666 (+)NCBI
UMICH_Zoey_3.11820,418,233 - 20,447,673 (+)NCBI
UNSW_CanFamBas_1.01819,970,682 - 20,000,166 (+)NCBI
UU_Cfam_GSD_1.01820,626,442 - 20,655,919 (+)NCBI
CD36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl999,605,181 - 99,782,105 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1999,685,748 - 99,782,296 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29110,037,583 - 110,106,975 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD36
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12168,214,875 - 68,309,336 (-)NCBI
ChlSab1.1 Ensembl2168,216,201 - 68,268,669 (-)Ensembl
Cd36
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473929,341,620 - 29,441,232 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005340670   ⟹   XP_005340727
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511862,236,264 - 62,269,004 (+)NCBI
SpeTri2.0NW_004936810805,556 - 838,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013365366   ⟹   XP_013220820
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511862,236,247 - 62,269,004 (+)NCBI
SpeTri2.0NW_004936810805,551 - 838,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013365367   ⟹   XP_013220821
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511862,222,603 - 62,269,004 (+)NCBI
SpeTri2.0NW_004936810791,823 - 838,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013365368   ⟹   XP_013220822
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511862,222,618 - 62,269,004 (+)NCBI
SpeTri2.0NW_004936810791,835 - 838,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013365369   ⟹   XP_013220823
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511862,236,271 - 62,269,004 (+)NCBI
SpeTri2.0NW_004936810805,556 - 838,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040291695   ⟹   XP_040147629
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511862,222,643 - 62,269,004 (+)NCBI
RefSeq Acc Id: XM_040291696   ⟹   XP_040147630
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511862,188,852 - 62,269,004 (+)NCBI
RefSeq Acc Id: XM_040291697   ⟹   XP_040147631
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511862,188,853 - 62,269,004 (+)NCBI
RefSeq Acc Id: XM_040291698   ⟹   XP_040147632
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511862,188,869 - 62,269,004 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_013220821   ⟸   XM_013365367
- UniProtKB: I3MBR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013220822   ⟸   XM_013365368
- UniProtKB: I3MBR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013220820   ⟸   XM_013365366
- UniProtKB: I3MBR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005340727   ⟸   XM_005340670
- UniProtKB: I3MBR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013220823   ⟸   XM_013365369
- UniProtKB: I3MBR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040147630   ⟸   XM_040291696
RefSeq Acc Id: XP_040147631   ⟸   XM_040291697
RefSeq Acc Id: XP_040147632   ⟸   XM_040291698
RefSeq Acc Id: XP_040147629   ⟸   XM_040291695


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008485 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000007617 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000025792 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008498 UniProtKB/TrEMBL
  ENSSTOT00000036004 UniProtKB/TrEMBL
InterPro CD36/SCARB1/SNMP1 UniProtKB/TrEMBL
  CD36_chordates UniProtKB/TrEMBL
  CD36_fam UniProtKB/TrEMBL
NCBI Gene Cd36 ENTREZGENE
PANTHER PTHR11923 UniProtKB/TrEMBL
  PTHR11923:SF12 UniProtKB/TrEMBL
Pfam CD36 UniProtKB/TrEMBL
PRINTS CD36ANTIGEN UniProtKB/TrEMBL
  CD36FAMILY UniProtKB/TrEMBL
UniProt I3MBR1 ENTREZGENE, UniProtKB/TrEMBL