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Strain: SHR-Tg(EEF1A1-Cd36)19Ipcv

Symbol: SHR-Tg(EEF1A1-Cd36)19Ipcv
Strain: SHR-Tg(EEF1A1-Cd36)19
Substrain: Ipcv
RGD ID: 2302149
Citation ID: RRID:RGD_2302149
Ontology ID: RS:0001688
Alleles: Cd36
Also Known As: SHR/Ola-TgN(Ef1aCd36)19Ipcv;SHR-TG19; SHR-Tg(Ef1a-Cd36)19Ipcv
Type: transgenic
Available Source: Not Available
Origination: Czech Academy of Sciences, Prague, Czech Republic
Description: Generated by microinjecting SHR/OlaIpcv zygotes with wild type Cd36 DNA from WKY cloned into Invitrogen pEF1/V5-HisA vector (with human EEF1A1 promoter)
Last Known Status: Unknown





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Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats. Pravenec M, etal., Nat Genet 2001 Feb;27(2):156-8.
2. Recent progress in the genetics of spontaneously hypertensive rats. Pravenec M, etal., Physiol Res. 2014;63 Suppl 1:S1-8.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other Harbors one copy of the transgene 68930
strain_phys_biochem Cd36 expression detected in brain, muscle, liver, heart, fat and kidney 68930

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-01 SHR-Tg(EEF1A1-Cd36)19Ipcv    SHR-Tg(Ef1a-Cd36)19Ipcv    Symbol and/or name change 68913 APPROVED