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Gene: CD36 (CD36 molecule) Homo sapiens
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Symbol: CD36
Name: CD36 molecule
Description: Exhibits several functions, including amyloid-beta binding activity; cargo receptor activity; and low-density lipoprotein particle binding activity. Involved in several processes, including amyloid-beta clearance by cellular catabolic process; cellular response to amyloid-beta; and second-messenger-mediated signaling. Localizes to several cellular components, including the Golgi apparatus; cell; and membrane raft. Implicated in several diseases, including hemolytic-uremic syndrome; osteoarthritis; pemphigus; platelet-type bleeding disorder 10; and type 2 diabetes mellitus. Biomarker of several diseases, including autoimmune hypersensitivity disease (multiple); hematologic cancer (multiple); myositis (multiple); rheumatic heart disease; and sickle cell anemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BDPLT10; CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule (thrombospondin receptor); CHDS7; cluster determinant 36; FAT; fatty acid translocase; glycoprotein IIIb; GP3B; GP4; GPIIIB; GPIV; leukocyte differentiation antigen CD36; PAS IV; PAS-4 protein; PASIV; platelet glycoprotein 4; platelet glycoprotein IV; SCARB3; scavenger receptor class B, member 3
Orthologs:
Mus musculus (house mouse) : Cd36 (CD36 molecule)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd36 (CD36 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd36 (CD36 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD36 (CD36 molecule)
Canis lupus familiaris (dog) : CD36 (CD36 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd36 (CD36 molecule)
Sus scrofa (pig) : CD36 (CD36 molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38780,602,207 - 80,679,277 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37780,231,504 - 80,308,593 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36780,069,459 - 80,144,262 (+)NCBINCBI36hg18NCBI36
Build 34779,912,607 - 79,950,974NCBI
Celera774,932,098 - 75,009,206 (+)NCBI
Cytogenetic Map7q21.11NCBI
HuRef774,834,319 - 74,911,371 (+)NCBIHuRef
CHM1_1780,162,020 - 80,239,042 (+)NCBICHM1_1
CRA_TCAGchr7v2779,562,929 - 79,640,010 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CD36
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619554
Created: 2002-07-23
Species: Homo sapiens
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.