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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2301
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd36
Name: CD36 molecule
Acc ID: CHEBI:34317
Term: 3,3',4,4',5-pentachlorobiphenyl
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID: MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd36decreases expressionEXP 6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD36 mRNAPMID:20959002 PMID:22824115
Cd36multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD36 mRNA]PMID:22824115
Cd36affects expressionISOCd36 (Mus musculus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl affects the expression of CD36 mRNAPMID:20702594
Cd36increases expressionISOCd36 (Mus musculus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CD36 mRNAPMID:23994337 PMID:28163111 PMID:28973532 PMID:29216392 PMID:30312631
Cd36multiple interactionsISOCd36 (Mus musculus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CD36 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of CD36 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CD36 mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CD36 mRNA]PMID:28163111 PMID:28973532 PMID:30312631
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