CD36 (CD36 molecule) - Rat Genome Database
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Gene: CD36 (CD36 molecule) Pan paniscus
Analyze
Symbol: CD36
Name: CD36 molecule
RGD ID: 11820688
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); high-density lipoprotein particle binding (ortholog); lipid binding (ortholog); INVOLVED IN amyloid fibril formation (ortholog); amyloid-beta clearance by cellular catabolic process (ortholog); apoptotic cell clearance (ortholog); PARTICIPATES IN retinol metabolic pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); Alcoholic Fatty Liver (ortholog); allergic contact dermatitis (ortholog); FOUND IN apical part of cell (ortholog); brush border membrane (ortholog); caveola (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: platelet glycoprotein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1786,228,856 - 86,305,865 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl786,265,114 - 86,305,865 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0772,566,478 - 72,643,517 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Lung Injury  (ISO)
Alcoholic Fatty Liver  (ISO)
allergic contact dermatitis  (ISO)
Alzheimer's disease  (ISO)
arteriosclerosis  (ISO)
atherosclerosis  (ISO)
atrial fibrillation  (ISO)
blood platelet disease  (ISO)
brain ischemia  (ISO)
Cardiac Arrhythmias  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
celiac disease  (ISO)
Cerebral Hemorrhage  (ISO)
cerebral infarction  (ISO)
cerebral malaria  (ISO)
chronic myeloid leukemia  (ISO)
colitis  (ISO)
corneal neovascularization  (ISO)
Coronary Disease  (ISO)
dermatomyositis  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (ISO)
dilated cardiomyopathy  (ISO)
endometriosis  (ISO)
epilepsy  (ISO)
essential thrombocythemia  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
fatty liver disease  (ISO)
glucose intolerance  (ISO)
granulomatosis with polyangiitis  (ISO)
Hematoma  (ISO)
hemolytic-uremic syndrome  (ISO)
Hypercholesterolemia  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
inclusion body myositis  (ISO)
Inflammation  (ISO)
Insulin Resistance  (ISO)
Knee Osteoarthritis  (ISO)
liver cirrhosis  (ISO)
macular degeneration  (ISO)
malaria  (ISO)
Metabolic Syndrome  (ISO)
middle cerebral artery infarction  (ISO)
Mycobacterium Infections  (ISO)
myeloid neoplasm  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
nephrosis  (ISO)
non-alcoholic fatty liver disease  (ISO)
obesity  (ISO)
osteoarthritis  (ISO)
pemphigus  (ISO)
platelet-type bleeding disorder 10  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
polycystic ovary syndrome  (ISO)
polycythemia vera  (ISO)
primary immunodeficiency disease  (ISO)
pulmonary fibrosis  (ISO)
pulmonary tuberculosis  (ISO)
relapsing-remitting multiple sclerosis  (ISO)
Reperfusion Injury  (ISO)
Retroperitoneal Fibrosis  (ISO)
rheumatic heart disease  (ISO)
Sepsis  (ISO)
sickle cell anemia  (ISO)
silicosis  (ISO)
Staphylococcal Infections  (ISO)
Tachycardia  (ISO)
thrombotic thrombocytopenic purpura  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
visual epilepsy  (ISO)
Weight Gain  (ISO)
Wounds, Penetrating  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
amyloid fibril formation  (ISO)
amyloid-beta clearance by cellular catabolic process  (ISO)
apoptotic cell clearance  (ISO)
cell surface receptor signaling pathway  (ISO)
cell-cell adhesion via plasma-membrane adhesion molecules  (ISO)
cellular response to amyloid-beta  (ISO)
cellular response to bacterial lipopeptide  (ISO)
cellular response to diacyl bacterial lipopeptide  (ISO)
cellular response to hydroperoxide  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to lipoteichoic acid  (ISO)
cellular response to low-density lipoprotein particle stimulus  (ISO)
cellular response to oxidised low-density lipoprotein particle stimulus  (ISO)
cGMP-mediated signaling  (ISO)
cholesterol import  (ISO)
cholesterol transport  (ISO)
defense response to Gram-positive bacterium  (ISO)
digestive tract development  (ISO)
eating behavior  (ISO)
energy homeostasis  (ISO)
fatty acid metabolic process  (ISO)
fatty acid oxidation  (ISO)
fatty acid transport  (ISO)
glucose homeostasis  (ISO)
intestinal absorption  (ISO)
intestinal cholesterol absorption  (ISO)
lipid storage  (ISO)
lipid transport across blood-brain barrier  (ISO)
lipoprotein transport  (ISO)
long-chain fatty acid import across plasma membrane  (ISO)
long-chain fatty acid import into cell  (ISO)
long-chain fatty acid metabolic process  (ISO)
long-chain fatty acid transport  (ISO)
low-density lipoprotein particle clearance  (ISO)
low-density lipoprotein particle mediated signaling  (ISO)
maternal placenta development  (ISO)
negative regulation of angiogenesis  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of protein import into nucleus  (ISO)
negative regulation of systemic arterial blood pressure  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
nitric oxide mediated signal transduction  (ISO)
oxidised low-density lipoprotein particle clearance  (ISO)
phagocytosis, recognition  (ISO)
plasma lipoprotein particle clearance  (ISO)
positive regulation of blood coagulation  (ISO)
positive regulation of blood microparticle formation  (ISO)
positive regulation of cell death  (ISO)
positive regulation of cell-matrix adhesion  (ISO)
positive regulation of cholesterol storage  (ISO)
positive regulation of cold-induced thermogenesis  (ISO)
positive regulation of cytokine production  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of glycogen biosynthetic process  (ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
positive regulation of interleukin-12 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of macrophage cytokine production  (ISO)
positive regulation of macrophage derived foam cell differentiation  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of nitric oxide biosynthetic process  (ISO)
positive regulation of NLRP3 inflammasome complex assembly  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of phagocytosis  (ISO)
positive regulation of phagocytosis, engulfment  (ISO)
positive regulation of reactive oxygen species biosynthetic process  (ISO)
positive regulation of reactive oxygen species metabolic process  (ISO)
positive regulation of triglyceride metabolic process  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
receptor internalization  (ISO)
receptor-mediated endocytosis  (ISO)
regulation of action potential  (ISO)
regulation of protein-containing complex assembly  (ISO)
regulation of removal of superoxide radicals  (ISO)
regulation of toll-like receptor signaling pathway  (ISO)
response to activity  (ISO)
response to bacterium  (ISO)
response to drug  (ISO)
response to estradiol  (ISO)
response to fatty acid  (ISO)
response to growth hormone  (ISO)
response to linoleic acid  (ISO)
response to lipid  (ISO)
response to mechanical stimulus  (ISO)
response to nutrient  (ISO)
response to stilbenoid  (ISO)
sensory perception of taste  (ISO)
short-chain fatty acid transport  (ISO)
triglyceride metabolic process  (ISO)
triglyceride transport  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
CD36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1786,228,856 - 86,305,865 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl786,265,114 - 86,305,865 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0772,566,478 - 72,643,517 (+)NCBIMhudiblu_PPA_v0panPan3
CD36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl780,369,575 - 80,679,277 (+)EnsemblGRCh38hg38GRCh38
GRCh38780,602,207 - 80,679,277 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37780,231,523 - 80,308,593 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36780,069,459 - 80,144,262 (+)NCBINCBI36hg18NCBI36
Build 34779,912,607 - 79,950,974NCBI
Celera774,932,098 - 75,009,206 (+)NCBI
Cytogenetic Map7q21.11NCBI
HuRef774,834,319 - 74,911,371 (+)NCBIHuRef
CHM1_1780,162,020 - 80,239,042 (+)NCBICHM1_1
CRA_TCAGchr7v2779,562,929 - 79,640,010 (+)NCBI
Cd36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39517,986,688 - 18,093,957 (-)NCBIGRCm39mm39
GRCm39 Ensembl517,986,688 - 18,093,799 (-)Ensembl
GRCm38517,781,690 - 17,888,959 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl517,781,690 - 17,888,801 (-)EnsemblGRCm38mm10GRCm38
MGSCv37517,287,508 - 17,394,777 (-)NCBIGRCm37mm9NCBIm37
MGSCv36517,293,840 - 17,347,520 (-)NCBImm8
Celera514,757,802 - 14,864,361 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map58.11NCBI
Cd36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2417,317,343 - 17,410,084 (+)NCBI
Rnor_6.0 Ensembl414,001,761 - 14,249,749 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0414,150,309 - 14,191,498 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0414,125,297 - 14,166,434 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4413,534,582 - 13,554,416 (+)NCBIRGSC3.4rn4RGSC3.4
Celera412,880,238 - 12,941,086 (+)NCBICelera
Cytogenetic Map4q11NCBI
Cd36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554105,003,668 - 5,075,313 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554105,003,720 - 5,120,903 (-)NCBIChiLan1.0ChiLan1.0
CD36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1820,339,050 - 20,372,639 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11820,299,808 - 20,375,856 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Cd36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936810791,823 - 838,303 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl999,605,181 - 99,782,105 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1999,685,748 - 99,782,296 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29110,037,583 - 110,106,975 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD36
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12168,214,875 - 68,309,336 (-)NCBI
ChlSab1.1 Ensembl2168,216,201 - 68,268,669 (-)Ensembl
Cd36
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473929,341,620 - 29,441,232 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000005346   ⟹   ENSPPAP00000001139
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl786,265,114 - 86,300,693 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000005404   ⟹   ENSPPAP00000001150
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl786,273,339 - 86,299,938 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000005437   ⟹   ENSPPAP00000001153
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl786,273,339 - 86,289,611 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000005452   ⟹   ENSPPAP00000001157
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl786,283,116 - 86,305,865 (+)Ensembl
RefSeq Acc Id: XM_003822746   ⟹   XP_003822794
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1786,265,114 - 86,305,865 (+)NCBI
Mhudiblu_PPA_v0772,601,893 - 72,643,517 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008976330   ⟹   XP_008974578
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1786,228,856 - 86,305,865 (+)NCBI
Mhudiblu_PPA_v0772,566,478 - 72,643,517 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008976331   ⟹   XP_008974579
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1786,250,690 - 86,305,865 (+)NCBI
Mhudiblu_PPA_v0772,588,324 - 72,643,517 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008976333   ⟹   XP_008974581
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1786,228,909 - 86,305,865 (+)NCBI
Mhudiblu_PPA_v0772,566,478 - 72,641,259 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008976334   ⟹   XP_008974582
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1786,263,527 - 86,305,865 (+)NCBI
Mhudiblu_PPA_v0772,600,418 - 72,641,259 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034964334   ⟹   XP_034820225
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0772,590,459 - 72,641,259 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_008974578   ⟸   XM_008976330
- Sequence:
RefSeq Acc Id: XP_008974581   ⟸   XM_008976333
- Sequence:
RefSeq Acc Id: XP_008974579   ⟸   XM_008976331
- Sequence:
RefSeq Acc Id: XP_008974582   ⟸   XM_008976334
- Sequence:
RefSeq Acc Id: XP_003822794   ⟸   XM_003822746
- Sequence:
RefSeq Acc Id: XP_034820225   ⟸   XM_034964334
RefSeq Acc Id: ENSPPAP00000001139   ⟸   ENSPPAT00000005346
RefSeq Acc Id: ENSPPAP00000001150   ⟸   ENSPPAT00000005404
RefSeq Acc Id: ENSPPAP00000001153   ⟸   ENSPPAT00000005437
RefSeq Acc Id: ENSPPAP00000001157   ⟸   ENSPPAT00000005452


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000004914 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000001139 UniProtKB/TrEMBL
  ENSPPAP00000001150 UniProtKB/TrEMBL
  ENSPPAP00000001153 UniProtKB/TrEMBL
  ENSPPAP00000001157 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000005346 UniProtKB/TrEMBL
  ENSPPAT00000005404 UniProtKB/TrEMBL
  ENSPPAT00000005437 UniProtKB/TrEMBL
  ENSPPAT00000005452 UniProtKB/TrEMBL
InterPro CD36/SCARB1/SNMP1 UniProtKB/TrEMBL
  CD36_chordates UniProtKB/TrEMBL
  CD36_fam UniProtKB/TrEMBL
KEGG Report pps:100984927 UniProtKB/TrEMBL
NCBI Gene CD36 ENTREZGENE
PANTHER PTHR11923 UniProtKB/TrEMBL
  PTHR11923:SF12 UniProtKB/TrEMBL
Pfam CD36 UniProtKB/TrEMBL
PRINTS CD36ANTIGEN UniProtKB/TrEMBL
  CD36FAMILY UniProtKB/TrEMBL
UniProt A0A2R8Z8C2_PANPA UniProtKB/TrEMBL
  A0A2R8Z8C9_PANPA UniProtKB/TrEMBL
  A0A2R8Z8H3_PANPA UniProtKB/TrEMBL
  A0A2R8ZCA0_PANPA UniProtKB/TrEMBL