Dbf4 (DBF4-CDC7 kinase regulatory subunit) - Rat Genome Database

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Gene: Dbf4 (DBF4-CDC7 kinase regulatory subunit) Rattus norvegicus
Analyze
Symbol: Dbf4
Name: DBF4-CDC7 kinase regulatory subunit (Ensembl:DBF4 zinc finger)
RGD ID: 1305854
Description: Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of nuclear cell cycle DNA replication and regulation of cell cycle phase transition. Predicted to be located in nuclear body. Predicted to be part of Dbf4-dependent protein kinase complex. Orthologous to human DBF4 (DBF4-CDC7 kinase regulatory subunit); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DBF4 homolog; DBF4 homolog (S. cerevisiae); DBF4 zinc finger; LOC100912278; LOC103690019; LOC312046; protein DBF4 homolog A; protein DBF4 homolog A-like; RGD1305854; similar to DBF4-related protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8426,631,491 - 26,656,080 (+)NCBIGRCr8
mRatBN7.2425,676,570 - 25,701,152 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl425,676,634 - 25,701,066 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx430,666,368 - 30,690,789 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0426,592,600 - 26,617,020 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0424,966,510 - 24,990,871 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0422,898,527 - 22,914,091 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl422,898,527 - 22,914,177 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0422,594,056 - 22,617,580 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4422,522,387 - 22,547,180 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1422,522,504 - 22,554,536 (-)NCBI
Celera421,162,668 - 21,187,012 (+)NCBICelera
Cytogenetic Map4q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deguelin  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
Enterolactone  (ISO)
equol  (ISO)
etoposide  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
geraniol  (ISO)
GW 4064  (ISO)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lidocaine  (EXP)
melphalan  (ISO)
mitomycin C  (ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
nickel atom  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
poly(propylene imine) macromolecule  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
silver(1+) nitrate  (ISO)
simvastatin  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
toluene 2,4-diisocyanate  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11250080  


Genomics

Comparative Map Data
Dbf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8426,631,491 - 26,656,080 (+)NCBIGRCr8
mRatBN7.2425,676,570 - 25,701,152 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl425,676,634 - 25,701,066 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx430,666,368 - 30,690,789 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0426,592,600 - 26,617,020 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0424,966,510 - 24,990,871 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0422,898,527 - 22,914,091 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl422,898,527 - 22,914,177 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0422,594,056 - 22,617,580 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4422,522,387 - 22,547,180 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1422,522,504 - 22,554,536 (-)NCBI
Celera421,162,668 - 21,187,012 (+)NCBICelera
Cytogenetic Map4q12NCBI
DBF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38787,876,493 - 87,909,553 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl787,876,216 - 87,909,553 (+)EnsemblGRCh38hg38GRCh38
GRCh37787,505,808 - 87,538,868 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36787,343,480 - 87,376,792 (+)NCBINCBI36Build 36hg18NCBI36
Celera782,210,104 - 82,243,416 (+)NCBICelera
Cytogenetic Map7q21.12NCBI
HuRef782,115,419 - 82,148,733 (+)NCBIHuRef
CHM1_1787,435,710 - 87,469,023 (+)NCBICHM1_1
T2T-CHM13v2.0789,126,406 - 89,159,470 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2786,836,862 - 86,870,174 (+)NCBI
Dbf4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3958,446,969 - 8,472,789 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl58,446,973 - 8,472,716 (-)EnsemblGRCm39 Ensembl
GRCm3858,396,969 - 8,422,725 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl58,396,973 - 8,422,716 (-)EnsemblGRCm38mm10GRCm38
MGSCv3758,397,011 - 8,422,606 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3658,403,017 - 8,428,612 (-)NCBIMGSCv36mm8
Celera58,317,304 - 8,342,900 (-)NCBICelera
Cytogenetic Map5A1NCBI
cM Map53.43NCBI
Dbf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554325,245,116 - 5,265,923 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554325,245,039 - 5,266,104 (+)NCBIChiLan1.0ChiLan1.0
DBF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26105,758,069 - 105,789,719 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17154,022,707 - 154,054,300 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0779,872,955 - 79,904,778 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1793,521,636 - 93,553,134 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl793,521,856 - 93,552,920 (+)Ensemblpanpan1.1panPan2
DBF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11413,983,832 - 14,019,917 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1413,803,576 - 14,019,704 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1413,555,264 - 13,591,239 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01413,748,680 - 13,784,872 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1413,748,590 - 13,784,872 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11413,952,327 - 13,988,505 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01413,678,096 - 13,714,258 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01413,963,669 - 13,999,860 (+)NCBIUU_Cfam_GSD_1.0
Dbf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511827,014,211 - 27,038,199 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936763963,195 - 986,926 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936763963,195 - 987,198 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DBF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl992,448,731 - 92,481,379 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1992,449,385 - 92,481,959 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29101,840,273 - 101,871,578 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DBF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12161,029,913 - 61,062,806 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2161,029,498 - 61,062,433 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604243,012,707 - 43,045,596 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dbf4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248095,471,230 - 5,493,974 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248095,471,056 - 5,494,188 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dbf4
152 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:330
Count of miRNA genes:149
Interacting mature miRNAs:170
Transcripts:ENSRNOT00000011351, ENSRNOT00000072455
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42133334339505420Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4130372989Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4127716890Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
8552803Bw144Body weight QTL 14416body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)42271068534430484Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4127716890Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4129494328Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
1358201Gluco12Glucose level QTL121.6adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake (CMO:0000870)4521839229593287Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4132584199Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4131934116Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1354665Stl10Serum triglyceride level QTL 103.57blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42133334344463908Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat

Markers in Region
BF393841  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2425,672,222 - 25,672,364 (+)MAPPERmRatBN7.2
Rnor_6.0422,657,499 - 22,657,640NCBIRnor6.0
Rnor_5.0422,589,484 - 22,589,625UniSTSRnor5.0
RGSC_v3.4422,551,473 - 22,551,614UniSTSRGSC3.4
Celera421,158,234 - 21,158,375UniSTS
RH 3.4 Map4169.0UniSTS
Cytogenetic Map4q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 18 54 54 54 64 42 82
Low 21 75 113 52 69 52 15 5 119 67 63 53 3
Below cutoff 48 60 41 41 18 34 67 6 18

Sequence


Ensembl Acc Id: ENSRNOT00000011351
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl422,662,216 - 22,685,474 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000072455   ⟹   ENSRNOP00000065840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl425,676,634 - 25,698,351 (+)Ensembl
Rnor_6.0 Ensembl422,898,527 - 22,913,973 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076123   ⟹   ENSRNOP00000068111
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl425,676,657 - 25,701,066 (+)Ensembl
Rnor_6.0 Ensembl422,898,527 - 22,914,177 (+)Ensembl
RefSeq Acc Id: NM_001191748   ⟹   NP_001178677
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8426,631,586 - 26,655,994 (+)NCBI
mRatBN7.2425,676,657 - 25,701,066 (+)NCBI
Rnor_6.0422,898,527 - 22,914,091 (+)NCBI
Rnor_5.0422,594,056 - 22,617,580 (+)NCBI
Celera421,162,668 - 21,187,012 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107501   ⟹   XP_038963429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8426,631,491 - 26,656,080 (+)NCBI
mRatBN7.2425,676,570 - 25,701,152 (+)NCBI
RefSeq Acc Id: XM_039107502   ⟹   XP_038963430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8426,632,872 - 26,656,080 (+)NCBI
mRatBN7.2425,677,947 - 25,701,152 (+)NCBI
RefSeq Acc Id: XM_039107503   ⟹   XP_038963431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8426,646,343 - 26,656,080 (+)NCBI
mRatBN7.2425,691,383 - 25,701,152 (+)NCBI
RefSeq Acc Id: NP_001178677   ⟸   NM_001191748
- UniProtKB: A0A096MJF6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000065840   ⟸   ENSRNOT00000072455
Ensembl Acc Id: ENSRNOP00000068111   ⟸   ENSRNOT00000076123
RefSeq Acc Id: XP_038963429   ⟸   XM_039107501
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038963430   ⟸   XM_039107502
- Peptide Label: isoform X2
- UniProtKB: A6K240 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963431   ⟸   XM_039107503
- Peptide Label: isoform X2
- UniProtKB: A6K240 (UniProtKB/TrEMBL)
Protein Domains
BRCT   DBF4-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R8P0-F1-model_v2 AlphaFold M0R8P0 1-594 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305854 AgrOrtholog
BioCyc Gene G2FUF-45822 BioCyc
Ensembl Genes ENSRNOG00000008513 Ensembl
  ENSRNOG00000050482 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072455.3 UniProtKB/TrEMBL
  ENSRNOT00000076123.3 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.40 UniProtKB/TrEMBL
  6.10.250.3410 UniProtKB/TrEMBL
InterPro BRCT_dom UniProtKB/TrEMBL
  BRCT_dom_sf UniProtKB/TrEMBL
  Replication_Regulatory_Kinase UniProtKB/TrEMBL
  RUNDC3A_B UniProtKB/TrEMBL
  Znf_DBF UniProtKB/TrEMBL
  Znf_DBF_sf UniProtKB/TrEMBL
KEGG Report rno:312046 UniProtKB/TrEMBL
NCBI Gene 312046 ENTREZGENE
PANTHER ACTIVATOR OF S-PHASE KINASE-RELATED UniProtKB/TrEMBL
  PROTEIN DBF4 HOMOLOG A UniProtKB/TrEMBL
  RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 UniProtKB/TrEMBL
  RUN DOMAIN-CONTAINING PROTEIN 3B UniProtKB/TrEMBL
Pfam zf-DBF UniProtKB/TrEMBL
PhenoGen Dbf4 PhenoGen
PROSITE BRCT UniProtKB/TrEMBL
  ZF_DBF4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008513 RatGTEx
  ENSRNOG00000050482 RatGTEx
SMART ZnF_DBF UniProtKB/TrEMBL
Superfamily-SCOP SSF52113 UniProtKB/TrEMBL
UniProt A0A096MJF6 ENTREZGENE, UniProtKB/TrEMBL
  A6K240 ENTREZGENE, UniProtKB/TrEMBL
  M0R8P0_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-01-08 Dbf4  DBF4-CDC7 kinase regulatory subunit  Dbf4  DBF4 zinc finger  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2021-03-09 Dbf4  DBF4 zinc finger  LOC103690019  protein DBF4 homolog A-like  Data merged from RGD:9449239 737654 PROVISIONAL
2015-07-29 Dbf4  DBF4 zinc finger  LOC100912278  protein DBF4 homolog A-like  Data merged from RGD:6488169 737654 PROVISIONAL
2014-08-25 LOC103690019  protein DBF4 homolog A-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2014-03-07 Dbf4  DBF4 zinc finger  Dbf4  DBF4 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100912278  protein DBF4 homolog A-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-07 Dbf4  DBF4 homolog (S. cerevisiae)  RGD1305854_predicted  similar to DBF4-related protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1305854_predicted  similar to DBF4-related protein (predicted)  LOC312046_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC312046_predicted  similar to DBF4-related protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL