(-)-gambogic acid decreases expression ISO RGD:732334 6480464 gambogic acid results in decreased expression of TYMS mRNA CTD PMID:19084572 (-)-gambogic acid multiple interactions ISO RGD:732334 6480464 gambogic acid inhibits the reaction [Fluorouracil results in increased expression of TYMS mRNA] CTD PMID:19084572 1,2-dichloroethane increases expression ISO RGD:736838 6480464 ethylene dichloride results in increased expression of TYMS mRNA CTD PMID:28960355 1,2-dimethylhydrazine decreases expression ISO RGD:736838 6480464 1, 2-Dimethylhydrazine results in decreased expression of TYMS mRNA CTD PMID:22206623 1-chloro-2,4-dinitrobenzene increases expression ISO RGD:736838 6480464 Dinitrochlorobenzene results in increased expression of TYMS mRNA CTD PMID:21404309 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of TYMS mRNA CTD PMID:30723492 14-Deoxy-11,12-didehydroandrographolide decreases expression ISO RGD:732334 6480464 14-deoxy-11, 12-didehydroandrographolide results in decreased expression of TYMS mRNA CTD PMID:22101062 17beta-estradiol increases expression ISO RGD:732334 6480464 Estradiol results in increased expression of TYMS mRNA CTD PMID:11179685 more ... 17beta-estradiol multiple interactions ISO RGD:732334 6480464 3 more ... CTD PMID:11179685 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732334 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of TYMS mRNA] CTD PMID:11179685 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:736838 6480464 Tetrachlorodibenzodioxin affects the expression of TYMS mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:736838 6480464 Tetrachlorodibenzodioxin results in increased expression of TYMS mRNA CTD PMID:15667827 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of TYMS mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:732334 6480464 Tetrachlorodibenzodioxin results in decreased expression of TYMS mRNA CTD PMID:21802500 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:732334 6480464 Tetrachlorodibenzodioxin results in increased expression of TYMS mRNA CTD PMID:19684285 2,3-dimethoxynaphthalene-1,4-dione increases expression ISO RGD:732334 6480464 2 more ... CTD PMID:17547211 , PMID:19031421 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of TYMS mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of TYMS mRNA CTD PMID:21346803 2-methylcholine affects expression ISO RGD:732334 6480464 beta-methylcholine affects the expression of TYMS mRNA CTD PMID:21179406 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of TYMS mRNA CTD PMID:14600272 more ... 3,3'-diindolylmethane multiple interactions ISO RGD:732334 6480464 3, 3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of TYMS mRNA] CTD PMID:11179685 3,7-dihydropurine-6-thione affects response to substance ISO RGD:732334 6480464 TYMS gene polymorphism affects the susceptibility to Mercaptopurine CTD PMID:15713801 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of TYMS protein CTD PMID:34915118 3-methylcholanthrene increases expression ISO RGD:732334 6480464 Methylcholanthrene results in increased expression of TYMS mRNA CTD PMID:22100608 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression ISO RGD:736838 6480464 Oxazolone results in increased expression of TYMS mRNA CTD PMID:21404309 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TYMS mRNA CTD PMID:14600272 more ... 4-hydroxyphenyl retinamide increases expression ISO RGD:736838 6480464 Fenretinide results in increased expression of TYMS mRNA CTD PMID:28973697 5,6,7,8-tetrahydrofolic acid increases activity EXP 6480464 5 more ... CTD PMID:187325 5-aza-2'-deoxycytidine affects expression ISO RGD:732334 6480464 Decitabine affects the expression of TYMS mRNA CTD PMID:23300844 5-fluorouracil multiple interactions ISO RGD:732334 6480464 [Arsenic Trioxide co-treated with Fluorouracil co-treated with Leucovorin] results in decreased expression of TYMS mRNA more ... CTD PMID:15213713 more ... 5-fluorouracil multiple interactions ISO RGD:736838 6480464 [Fluorouracil results in decreased activity of TYMS protein] which results in decreased abundance of Thymidine Monophosphate more ... CTD PMID:29258758 , PMID:9050858 5-fluorouracil decreases expression ISO RGD:736838 6480464 Fluorouracil results in decreased expression of TYMS CTD PMID:9050858 5-fluorouracil decreases activity ISO RGD:736838 6480464 Fluorouracil results in decreased activity of TYMS protein CTD PMID:29258758 , PMID:9299594 5-fluorouracil increases expression ISO RGD:732334 6480464 Fluorouracil results in increased expression of TYMS mRNA, Fluorouracil results in increased expression of TYMS protein CTD PMID:15109396 more ... 5-fluorouracil decreases activity EXP 6480464 Fluorouracil results in decreased activity of TYMS protein CTD PMID:9299594 5-fluorouracil increases response to substance ISO RGD:732334 6480464 TYMS gene polymorphism results in increased susceptibility to Fluorouracil more ... CTD PMID:15239142 more ... 5-fluorouracil affects response to substance ISO RGD:732334 6480464 TYMS affects the susceptibility to Fluorouracil more ... CTD PMID:10482907 more ... 5-fluorouracil decreases response to substance ISO RGD:732334 6480464 TYMS 3' UTR mutant form results in decreased susceptibility to Fluorouracil more ... CTD PMID:14970324 more ... 5-fluorouracil increases activity ISO RGD:732334 6480464 Fluorouracil results in increased activity of TYMS protein CTD PMID:16557585 5-fluorouracil decreases activity ISO RGD:732334 6480464 Fluorouracil results in decreased activity of TYMS protein CTD PMID:12739060 , PMID:17339891 5-fluorouracil affects expression ISO RGD:732334 6480464 Fluorouracil affects the expression of TYMS mRNA, Fluorouracil affects the expression of TYMS protein CTD PMID:18794807 5-formyltetrahydrofolic acid multiple interactions ISO RGD:732334 6480464 [arsenic trioxide co-treated with Fluorouracil co-treated with Leucovorin] results in decreased expression of TYMS mRNA more ... CTD PMID:16424979 more ... 5-formyltetrahydrofolic acid multiple interactions ISO RGD:736838 6480464 Leucovorin promotes the reaction [Fluorouracil results in decreased expression of TYMS] CTD PMID:9050858 5-iodo-2'-deoxyuridine affects uptake ISO RGD:736838 6480464 TYMS protein affects the uptake of Idoxuridine CTD PMID:15001691 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO RGD:736838 6480464 NLRP3 gene mutant form inhibits the reaction [Uric Acid results in decreased expression of TYMS mRNA] CTD PMID:23619996 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases expression ISO RGD:736838 6480464 Uric Acid results in decreased expression of TYMS mRNA CTD PMID:23619996 acetamide increases expression EXP 6480464 acetamide results in increased expression of TYMS mRNA CTD PMID:31881176 acetylleucyl-leucyl-norleucinal multiple interactions ISO RGD:732334 6480464 acetylleucyl-leucyl-norleucinal inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMS protein] CTD PMID:21444628 acrylamide decreases expression ISO RGD:732334 6480464 Acrylamide results in decreased expression of TYMS mRNA CTD PMID:32763439 aflatoxin B1 affects expression ISO RGD:732334 6480464 Aflatoxin B1 affects the expression of TYMS protein CTD PMID:20106945 aflatoxin B1 increases expression ISO RGD:732334 6480464 Aflatoxin B1 results in increased expression of TYMS mRNA CTD PMID:22100608 , PMID:27153756 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of TYMS mRNA CTD PMID:14600272 more ... all-trans-retinoic acid decreases expression ISO RGD:732334 6480464 Tretinoin results in decreased expression of TYMS mRNA CTD PMID:16249480 more ... ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of TYMS mRNA CTD PMID:16483693 antimony(0) increases expression ISO RGD:732334 6480464 Antimony results in increased expression of TYMS mRNA CTD PMID:17547211 antimycin A increases expression ISO RGD:732334 6480464 Antimycin A results in increased expression of TYMS mRNA CTD PMID:33512557 antirheumatic drug increases response to substance ISO RGD:732334 6480464 TYMS gene polymorphism results in increased susceptibility to Antirheumatic Agents CTD PMID:18322994 antirheumatic drug affects response to substance ISO RGD:732334 6480464 TYMS protein affects the susceptibility to Antirheumatic Agents CTD PMID:18322994 arsenite(3-) decreases expression ISO RGD:736838 6480464 arsenite results in decreased expression of TYMS mRNA CTD PMID:18929588 arsenous acid affects activity ISO RGD:732334 6480464 Arsenic Trioxide affects the activity of TYMS protein CTD PMID:25335113 arsenous acid decreases expression ISO RGD:732334 6480464 Arsenic Trioxide results in decreased expression of TYMS mRNA, Arsenic Trioxide results in decreased expression of TYMS protein CTD PMID:20530422 more ... arsenous acid decreases response to substance ISO RGD:732334 6480464 TYMS protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:24691991 arsenous acid affects expression ISO RGD:732334 6480464 Arsenic Trioxide affects the expression of TYMS mRNA, Arsenic Trioxide affects the expression of TYMS protein CTD PMID:20501625 , PMID:25335113 arsenous acid multiple interactions ISO RGD:732334 6480464 [Arsenic Trioxide co-treated with Fluorouracil co-treated with Leucovorin] results in decreased expression of TYMS mRNA CTD PMID:20501625 arsenous acid increases expression ISO RGD:732334 6480464 Arsenic Trioxide results in increased expression of TYMS mRNA CTD PMID:17547211 atrazine decreases expression ISO RGD:732334 6480464 Atrazine results in decreased expression of TYMS mRNA CTD PMID:22378314 azathioprine decreases expression ISO RGD:732334 6480464 Azathioprine results in decreased expression of TYMS mRNA CTD PMID:22623647 azoxystrobin affects expression ISO RGD:732334 6480464 azoxystrobin affects the expression of TYMS mRNA CTD PMID:33512557 belinostat decreases expression ISO RGD:732334 6480464 belinostat results in decreased expression of TYMS mRNA CTD PMID:19606018 benzatropine increases expression ISO RGD:732334 6480464 Benztropine results in increased expression of TYMS protein CTD PMID:34122009 benzo[a]pyrene increases expression ISO RGD:732334 6480464 Benzo(a)pyrene results in increased expression of TYMS mRNA CTD PMID:20106945 , PMID:32234424 benzo[a]pyrene increases expression ISO RGD:736838 6480464 Benzo(a)pyrene results in increased expression of TYMS mRNA CTD PMID:22228805 benzo[a]pyrene decreases expression ISO RGD:732334 6480464 Benzo(a)pyrene results in decreased expression of TYMS mRNA CTD PMID:20064835 , PMID:21802500 benzo[a]pyrene diol epoxide I affects expression ISO RGD:732334 6480464 7 more ... CTD PMID:20382639 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TYMS mRNA CTD PMID:18164116 bicalutamide decreases expression ISO RGD:732334 6480464 bicalutamide results in decreased expression of TYMS protein CTD PMID:17599054 Biflorin affects expression ISO RGD:732334 6480464 biflorin affects the expression of TYMS mRNA CTD PMID:27079618 bisphenol A increases expression ISO RGD:732334 6480464 bisphenol A results in increased expression of TYMS mRNA CTD PMID:16474171 bisphenol A decreases expression ISO RGD:732334 6480464 bisphenol A results in decreased expression of TYMS mRNA CTD PMID:29275510 bisphenol A affects expression ISO RGD:732334 6480464 bisphenol A affects the expression of TYMS mRNA CTD PMID:30903817 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TYMS mRNA CTD PMID:29097150 cadmium atom increases expression ISO RGD:732334 6480464 Cadmium results in increased expression of TYMS mRNA, Cadmium results in increased expression of TYMS protein CTD PMID:14499349 , PMID:17547211 cadmium dichloride increases expression ISO RGD:732334 6480464 Cadmium Chloride results in increased expression of TYMS mRNA CTD PMID:17547211 cadmium sulfate multiple interactions ISO RGD:732334 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of TYMS mRNA CTD PMID:18654764 caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of TYMS mRNA CTD PMID:20864626 calcitriol decreases expression ISO RGD:732334 6480464 Calcitriol results in decreased expression of TYMS mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:732334 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of TYMS mRNA CTD PMID:21592394 camptothecin increases expression ISO RGD:732334 6480464 Camptothecin results in increased expression of TYMS mRNA CTD PMID:16568373 capecitabine affects expression ISO RGD:732334 6480464 Capecitabine affects the expression of TYMS mRNA CTD PMID:16438929 capecitabine decreases response to substance ISO RGD:732334 6480464 TYMS protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 capecitabine multiple interactions ISO RGD:732334 6480464 [TYMS enhancer polymorphism co-treated with VEGFA gene SNP] affects the susceptibility to [Capecitabine co-treated with oxaliplatin] CTD PMID:21048041 carboplatin multiple interactions ISO RGD:732334 6480464 PCNA mRNA affects the reaction [TYMS mRNA affects the susceptibility to Carboplatin] CTD PMID:16685392 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of TYMS mRNA CTD PMID:18500788 chromium atom increases expression ISO RGD:732334 6480464 Chromium results in increased expression of TYMS mRNA CTD PMID:17547211 Cinobufagin multiple interactions ISO RGD:732334 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cinobufagin results in decreased expression of TYMS protein], cinobufagin promotes the reaction [Cycloheximide results in decreased expression of TYMS protein] CTD PMID:35427566 Cinobufagin decreases expression ISO RGD:732334 6480464 cinobufagin results in decreased expression of TYMS protein CTD PMID:35427566 cisplatin multiple interactions ISO RGD:732334 6480464 [Cisplatin co-treated with Fluorouracil] results in decreased expression of TYMS mRNA more ... CTD PMID:15737843 more ... cisplatin affects expression ISO RGD:732334 6480464 Cisplatin affects the expression of TYMS mRNA CTD PMID:23300844 cisplatin decreases response to substance ISO RGD:732334 6480464 TYMS protein results in decreased susceptibility to Cisplatin CTD PMID:21444628 cisplatin increases stability ISO RGD:732334 6480464 Cisplatin results in increased stability of TYMS mRNA CTD PMID:21444628 cisplatin increases expression ISO RGD:732334 6480464 Cisplatin results in increased expression of TYMS mRNA CTD PMID:16568373 more ... cisplatin increases activity ISO RGD:732334 6480464 Cisplatin results in increased activity of TYMS protein CTD PMID:16568373 cisplatin decreases degradation ISO RGD:732334 6480464 Cisplatin results in decreased degradation of TYMS protein CTD PMID:21444628 cobalt dichloride multiple interactions ISO RGD:732334 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of TYMS mRNA CTD PMID:18654764 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of TYMS mRNA CTD PMID:24386269 cobalt dichloride decreases expression ISO RGD:732334 6480464 cobaltous chloride results in decreased expression of TYMS mRNA CTD PMID:19320972 copper atom multiple interactions ISO RGD:732334 6480464 [NSC 689534 binds to Copper] which results in decreased expression of TYMS mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:732334 6480464 [NSC 689534 binds to Copper] which results in decreased expression of TYMS mRNA CTD PMID:20971185 copper(II) sulfate decreases expression ISO RGD:732334 6480464 Copper Sulfate results in decreased expression of TYMS mRNA CTD PMID:19549813 coumestrol increases expression ISO RGD:732334 6480464 Coumestrol results in increased expression of TYMS mRNA CTD PMID:19167446 coumestrol multiple interactions ISO RGD:732334 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 cycloheximide multiple interactions ISO RGD:732334 6480464 cinobufagin promotes the reaction [Cycloheximide results in decreased expression of TYMS protein], Cycloheximide inhibits the reaction [trichostatin A results in decreased expression of TYMS mRNA] CTD PMID:17172411 , PMID:35427566 cycloheximide decreases expression ISO RGD:732334 6480464 Cycloheximide results in decreased expression of TYMS protein CTD PMID:35427566 cyclosporin A decreases expression ISO RGD:732334 6480464 Cyclosporine results in decreased expression of TYMS mRNA CTD PMID:20106945 more ... cytarabine affects response to substance ISO RGD:732334 6480464 TYMS gene polymorphism affects the susceptibility to Cytarabine CTD PMID:15713801 cytarabine increases activity ISO RGD:736838 6480464 Cytarabine results in increased activity of TYMS protein CTD PMID:15816533 daunorubicin affects response to substance ISO RGD:732334 6480464 TYMS gene polymorphism affects the susceptibility to Daunorubicin CTD PMID:15713801 DDT decreases expression ISO RGD:732334 6480464 DDT results in decreased expression of TYMS mRNA CTD PMID:25014179 dextran sulfate multiple interactions ISO RGD:736838 6480464 [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TYMS mRNA CTD PMID:17893519 diarsenic trioxide decreases response to substance ISO RGD:732334 6480464 TYMS protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:24691991 diarsenic trioxide decreases expression ISO RGD:732334 6480464 Arsenic Trioxide results in decreased expression of TYMS mRNA, Arsenic Trioxide results in decreased expression of TYMS protein CTD PMID:20530422 more ... diarsenic trioxide affects expression ISO RGD:732334 6480464 Arsenic Trioxide affects the expression of TYMS mRNA, Arsenic Trioxide affects the expression of TYMS protein CTD PMID:20501625 , PMID:25335113 diarsenic trioxide increases expression ISO RGD:732334 6480464 Arsenic Trioxide results in increased expression of TYMS mRNA CTD PMID:17547211 diarsenic trioxide multiple interactions ISO RGD:732334 6480464 [Arsenic Trioxide co-treated with Fluorouracil co-treated with Leucovorin] results in decreased expression of TYMS mRNA CTD PMID:20501625 diarsenic trioxide affects activity ISO RGD:732334 6480464 Arsenic Trioxide affects the activity of TYMS protein CTD PMID:25335113 dibutyl phthalate decreases expression ISO RGD:736838 6480464 Dibutyl Phthalate results in decreased expression of TYMS mRNA CTD PMID:17361019 , PMID:21266533 dichlorine decreases expression EXP 6480464 Chlorine results in decreased expression of TYMS mRNA CTD PMID:18636392 dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] affects the expression of TYMS mRNA CTD PMID:18636392 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of TYMS mRNA CTD PMID:15890375 dioxygen decreases expression ISO RGD:736838 6480464 Oxygen deficiency results in decreased expression of TYMS mRNA CTD PMID:24205000 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases expression ISO RGD:732334 6480464 Antimony Potassium Tartrate results in increased expression of TYMS mRNA CTD PMID:17547211 DISTAMYCIN A decreases expression ISO RGD:732334 6480464 stallimycin results in decreased expression of TYMS mRNA CTD PMID:21814787 DISTAMYCIN A multiple interactions ISO RGD:732334 6480464 stallimycin analog results in decreased expression of and results in decreased activity of TYMS protein CTD PMID:21814787 doxifluridine affects expression ISO RGD:732334 6480464 doxifluridine affects the expression of TYMS mRNA CTD PMID:18630517 doxifluridine multiple interactions ISO RGD:732334 6480464 [Paclitaxel co-treated with doxifluridine] affects the expression of TYMS mRNA CTD PMID:18630517 doxifluridine decreases response to substance ISO RGD:732334 6480464 TYMS protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 doxorubicin multiple interactions ISO RGD:732334 6480464 [Doxorubicin co-treated with Paclitaxel] results in decreased expression of TYMS protein, Fluorouracil inhibits the reaction [[Doxorubicin co-treated with Paclitaxel] results in decreased expression of TYMS protein] CTD PMID:16168113 dTMP multiple interactions ISO RGD:736838 6480464 [Fluorouracil results in decreased activity of TYMS protein] which results in decreased abundance of Thymidine Monophosphate CTD PMID:29258758 dUMP multiple interactions ISO RGD:736838 6480464 [Fluorouracil results in decreased activity of TYMS protein] which results in increased abundance of 2'-deoxyuridylic acid CTD PMID:29258758 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of TYMS mRNA CTD PMID:29391264 Enterolactone multiple interactions ISO RGD:732334 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TYMS mRNA CTD PMID:19167446 Enterolactone increases expression ISO RGD:732334 6480464 2, 3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of TYMS mRNA CTD PMID:19167446 enzyme inhibitor multiple interactions ISO RGD:732334 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of TYMS protein CTD PMID:23301498 erlotinib hydrochloride decreases expression ISO RGD:732334 6480464 Erlotinib Hydrochloride results in decreased expression of TYMS protein CTD PMID:30136359 erlotinib hydrochloride multiple interactions ISO RGD:732334 6480464 Erlotinib Hydrochloride promotes the reaction [ results in decreased expression of TYMS protein], promotes the reaction [Erlotinib Hydrochloride results in decreased expression of TYMS protein] CTD PMID:30136359 ethyl methanesulfonate increases expression ISO RGD:732334 6480464 Ethyl Methanesulfonate results in increased expression of TYMS mRNA CTD PMID:23649840 etoposide affects response to substance ISO RGD:732334 6480464 TYMS gene polymorphism affects the susceptibility to Etoposide CTD PMID:15713801 fipronil increases expression EXP 6480464 fipronil results in increased expression of TYMS mRNA CTD PMID:23962444 floxuridine affects response to substance ISO RGD:732334 6480464 TYMS protein affects the susceptibility to Floxuridine CTD PMID:10482907 floxuridine increases response to substance ISO RGD:732334 6480464 TYMS results in increased susceptibility to Floxuridine CTD PMID:2537495 floxuridine decreases response to substance ISO RGD:732334 6480464 TYMS protein results in decreased susceptibility to Floxuridine CTD PMID:15040806 , PMID:17018589 flurbiprofen increases expression ISO RGD:736838 6480464 Flurbiprofen results in increased expression of TYMS mRNA CTD PMID:16949054 folic acid decreases activity ISO RGD:732334 6480464 Folic Acid analog results in decreased activity of TYMS protein CTD PMID:2909728 folic acid increases expression ISO RGD:732334 6480464 Folic Acid deficiency results in increased expression of TYMS mRNA CTD PMID:18623116 folic acid affects expression ISO RGD:732334 6480464 Folic Acid affects the expression of TYMS mRNA CTD PMID:17311948 , PMID:17320366 folic acid increases expression EXP 6480464 Folic Acid results in increased expression of TYMS protein CTD PMID:187325 furan increases expression EXP 6480464 furan results in increased expression of TYMS mRNA CTD PMID:25539665 , PMID:26194646 gefitinib decreases expression ISO RGD:732334 6480464 Gefitinib results in decreased expression of TYMS mRNA, Gefitinib results in decreased expression of TYMS protein CTD PMID:18347146 , PMID:30136359 gefitinib multiple interactions ISO RGD:732334 6480464 Gefitinib promotes the reaction [ results in decreased expression of TYMS protein] more ... CTD PMID:18347146 , PMID:30136359 genistein increases expression ISO RGD:732334 6480464 Genistein results in increased expression of TYMS mRNA CTD PMID:16474171 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of TYMS mRNA CTD PMID:22061828 , PMID:33387578 geraniol decreases expression ISO RGD:732334 6480464 geraniol results in decreased expression of TYMS mRNA CTD PMID:15374632 geraniol multiple interactions ISO RGD:732334 6480464 Fluorouracil promotes the reaction [geraniol results in decreased expression of TYMS mRNA] CTD PMID:15374632 Heliotrine increases expression EXP 6480464 heliotrine results in increased expression of TYMS mRNA CTD PMID:32419051 ICI D1694 decreases activity ISO RGD:732334 6480464 raltitrexed results in decreased activity of TYMS protein CTD PMID:17339891 ICI D1694 multiple interactions ISO RGD:732334 6480464 TYMS protein inhibits the reaction [raltitrexed results in increased expression of ANXA2 mRNA] more ... CTD PMID:15152939 , PMID:15161716 ICI D1694 affects response to substance ISO RGD:732334 6480464 TYMS protein affects the susceptibility to raltitrexed CTD PMID:10482907 , PMID:17339891 irinotecan multiple interactions ISO RGD:732334 6480464 TYMS mRNA affects the susceptibility to [Irinotecan co-treated with Fluorouracil co-treated with Leucovorin] CTD PMID:17454858 ivermectin decreases expression ISO RGD:732334 6480464 Ivermectin results in decreased expression of TYMS protein CTD PMID:32959892 ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of TYMS mRNA CTD PMID:20080153 lamivudine multiple interactions ISO RGD:732334 6480464 [Zidovudine co-treated with Lamivudine] results in decreased expression of TYMS mRNA CTD PMID:15784690 lead(II) chloride multiple interactions ISO RGD:732334 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of TYMS mRNA CTD PMID:18654764 lidocaine increases expression EXP 6480464 Lidocaine results in increased expression of TYMS mRNA CTD PMID:35283115 lipopolysaccharide multiple interactions ISO RGD:732334 6480464 Plant Extracts affects the reaction [Lipopolysaccharides affects the expression of TYMS mRNA] CTD PMID:28070326 lipopolysaccharide affects expression ISO RGD:732334 6480464 Lipopolysaccharides affects the expression of TYMS mRNA CTD PMID:28070326 malathion decreases expression ISO RGD:732334 6480464 Malathion results in decreased expression of TYMS mRNA CTD PMID:16079077 menadione affects expression ISO RGD:732334 6480464 Vitamin K 3 affects the expression of TYMS mRNA CTD PMID:20044591 mercaptopurine affects response to substance ISO RGD:732334 6480464 TYMS gene polymorphism affects the susceptibility to Mercaptopurine CTD PMID:15713801 mercury atom increases expression ISO RGD:732334 6480464 Mercury results in increased expression of TYMS mRNA CTD PMID:17547211 mercury(0) increases expression ISO RGD:732334 6480464 Mercury results in increased expression of TYMS mRNA CTD PMID:17547211 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of TYMS mRNA CTD PMID:15890375 methcathinone increases expression ISO RGD:732334 6480464 monomethylpropion results in increased expression of TYMS mRNA CTD PMID:22303338 methotrexate affects response to substance ISO RGD:732334 6480464 TYMS 3' UTR polymorphism affects the susceptibility to Methotrexate more ... CTD PMID:15713801 more ... methotrexate decreases expression ISO RGD:732334 6480464 Methotrexate results in decreased expression of TYMS mRNA CTD PMID:23897011 methotrexate increases expression ISO RGD:732334 6480464 Methotrexate results in increased expression of TYMS mRNA, Methotrexate results in increased expression of TYMS protein CTD PMID:22484375 , PMID:23838799 methotrexate increases expression ISO RGD:736838 6480464 Methotrexate results in increased expression of TYMS protein CTD PMID:22484375 methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of TYMS protein CTD PMID:187325 methotrexate increases response to substance ISO RGD:732334 6480464 TYMS protein results in increased susceptibility to Methotrexate, TYMS results in increased susceptibility to Methotrexate CTD PMID:16267625 , PMID:2537495 methotrexate decreases response to substance ISO RGD:732334 6480464 TYMS 5' UTR polymorphism results in decreased susceptibility to Methotrexate CTD PMID:16267625 methoxyacetic acid decreases expression EXP 6480464 methoxyacetic acid results in decreased expression of TYMS mRNA CTD PMID:20864626 methyl methanesulfonate increases expression ISO RGD:732334 6480464 Methyl Methanesulfonate results in increased expression of TYMS mRNA CTD PMID:22100608 , PMID:23649840 methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of TYMS mRNA CTD PMID:20864626 methylseleninic acid decreases expression ISO RGD:732334 6480464 methylselenic acid results in decreased expression of TYMS mRNA CTD PMID:12517777 methylseleninic acid affects expression ISO RGD:732334 6480464 methylselenic acid affects the expression of TYMS mRNA CTD PMID:14617803 mitomycin C increases expression ISO RGD:732334 6480464 Mitomycin results in increased expression of TYMS mRNA CTD PMID:16568373 Monobutylphthalate decreases expression EXP 6480464 monobutyl phthalate results in decreased expression of TYMS mRNA CTD PMID:20864626 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases expression ISO RGD:732334 6480464 N more ... CTD PMID:12888634 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:732334 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMS protein] more ... CTD PMID:17172411 more ... N-methyl-4-phenylpyridinium decreases expression ISO RGD:732334 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of TYMS mRNA CTD PMID:24810058 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TYMS mRNA CTD PMID:18164116 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of TYMS mRNA CTD PMID:14600272 , PMID:15890375 N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of TYMS mRNA CTD PMID:19716841 nickel atom increases expression ISO RGD:732334 6480464 Nickel results in increased expression of TYMS mRNA CTD PMID:25583101 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of TYMS mRNA CTD PMID:22110744 oxaliplatin multiple interactions ISO RGD:732334 6480464 [TYMS enhancer polymorphism co-treated with VEGFA gene SNP] affects the susceptibility to [Capecitabine co-treated with oxaliplatin] more ... CTD PMID:15213713 more ... oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of TYMS mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of TYMS mRNA CTD PMID:25729387 oxaliplatin decreases expression ISO RGD:732334 6480464 Oxaliplatin results in decreased expression of TYMS mRNA, Oxaliplatin results in decreased expression of TYMS protein CTD PMID:15057142 ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] affects the expression of TYMS mRNA CTD PMID:18636392 ozone multiple interactions ISO RGD:736838 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of TYMS mRNA more ... CTD PMID:25658374 , PMID:34911549 paclitaxel multiple interactions ISO RGD:732334 6480464 [Doxorubicin co-treated with Paclitaxel] results in decreased expression of TYMS protein more ... CTD PMID:16168113 more ... paclitaxel increases expression ISO RGD:732334 6480464 Paclitaxel results in increased expression of TYMS mRNA CTD PMID:16568373 paclitaxel affects expression ISO RGD:732334 6480464 Paclitaxel affects the expression of TYMS mRNA CTD PMID:18630517 palbociclib decreases expression ISO RGD:732334 6480464 palbociclib results in decreased expression of TYMS mRNA, palbociclib results in decreased expression of TYMS protein CTD PMID:20948315 , PMID:22869556 paracetamol decreases expression ISO RGD:732334 6480464 Acetaminophen results in decreased expression of TYMS mRNA CTD PMID:21420995 paracetamol affects expression ISO RGD:736838 6480464 Acetaminophen affects the expression of TYMS mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:732334 6480464 Acetaminophen results in increased expression of TYMS mRNA CTD PMID:22230336 pemetrexed decreases activity ISO RGD:732334 6480464 Pemetrexed results in decreased activity of TYMS protein CTD PMID:17339891 pemetrexed multiple interactions ISO RGD:732334 6480464 TYMS protein inhibits the reaction [Pemetrexed results in increased expression of FAS protein] CTD PMID:15161716 pemetrexed affects response to substance ISO RGD:732334 6480464 TYMS affects the susceptibility to Pemetrexed, TYMS protein affects the susceptibility to Pemetrexed CTD PMID:17339891 , PMID:21742432 phenobarbital affects expression ISO RGD:732334 6480464 Phenobarbital affects the expression of TYMS mRNA CTD PMID:19159669 phenobarbital affects expression ISO RGD:736838 6480464 Phenobarbital affects the expression of TYMS mRNA CTD PMID:23091169 phenolphthalein decreases activity ISO RGD:732334 6480464 Phenolphthalein results in decreased activity of TYMS protein CTD PMID:21696158 phorbol 13-acetate 12-myristate increases expression ISO RGD:732334 6480464 Tetradecanoylphorbol Acetate results in increased expression of TYMS mRNA CTD PMID:19031421 phytoestrogen increases expression ISO RGD:732334 6480464 Phytoestrogens results in increased expression of TYMS mRNA CTD PMID:18310284 piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of TYMS mRNA CTD PMID:15890375 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of TYMS mRNA CTD PMID:15890375 , PMID:19162173 pirinixic acid increases expression ISO RGD:736838 6480464 pirinixic acid results in increased expression of TYMS mRNA CTD PMID:23811191 potassium dichromate increases expression ISO RGD:732334 6480464 Potassium Dichromate results in increased expression of TYMS mRNA CTD PMID:17547211 prednisone affects response to substance ISO RGD:732334 6480464 TYMS gene polymorphism affects the susceptibility to Prednisone CTD PMID:15713801 progesterone increases expression ISO RGD:732334 6480464 Progesterone results in increased expression of TYMS mRNA CTD PMID:18070364 progesterone decreases expression ISO RGD:732334 6480464 Progesterone results in decreased expression of TYMS mRNA CTD PMID:21795739 purine-6-thiol affects response to substance ISO RGD:732334 6480464 TYMS gene polymorphism affects the susceptibility to Mercaptopurine CTD PMID:15713801 quercetin decreases expression ISO RGD:732334 6480464 Quercetin results in decreased expression of TYMS protein CTD PMID:16573383 quercetin increases expression ISO RGD:732334 6480464 Quercetin results in increased expression of TYMS mRNA CTD PMID:21632981 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of TYMS mRNA CTD PMID:17103110 quinazolines decreases activity ISO RGD:732334 6480464 Quinazolines analog results in decreased activity of TYMS protein CTD PMID:2909728 quizartinib decreases expression ISO RGD:732334 6480464 quizartinib results in decreased expression of TYMS protein CTD PMID:34665271 resveratrol multiple interactions ISO RGD:732334 6480464 [Coumestrol co-treated with Resveratrol] results in increased expression of TYMS mRNA, [Plant Extracts co-treated with Resveratrol] results in decreased expression of TYMS mRNA CTD PMID:19167446 , PMID:23557933 resveratrol increases expression ISO RGD:732334 6480464 resveratrol results in increased expression of TYMS mRNA CTD PMID:19167446 rotenone decreases expression ISO RGD:732334 6480464 Rotenone results in decreased expression of TYMS mRNA CTD PMID:24810058 more ... senecionine increases expression EXP 6480464 senecionine results in increased expression of TYMS mRNA CTD PMID:32419051 Senkirkine increases expression EXP 6480464 senkirkine results in increased expression of TYMS mRNA CTD PMID:32419051 silicon dioxide decreases expression ISO RGD:736838 6480464 Silicon Dioxide results in decreased expression of TYMS mRNA CTD PMID:19073995 silicon dioxide increases expression ISO RGD:736838 6480464 Silicon Dioxide results in increased expression of TYMS mRNA CTD PMID:29341224 simvastatin decreases expression ISO RGD:732334 6480464 Simvastatin results in decreased expression of TYMS mRNA, Simvastatin results in decreased expression of TYMS protein CTD PMID:17428261 sirolimus decreases expression ISO RGD:732334 6480464 Sirolimus results in decreased expression of TYMS, Sirolimus results in decreased expression of TYMS mRNA CTD PMID:19764996 , PMID:20682991 sodium arsenite increases expression ISO RGD:732334 6480464 sodium arsenite results in increased expression of TYMS mRNA CTD PMID:29301061 , PMID:34032870 sodium arsenite multiple interactions ISO RGD:732334 6480464 sodium arsenite promotes the reaction [TYMS protein binds to CAPRIN1 protein] CTD PMID:33939924 sodium dichromate affects expression EXP 6480464 sodium bichromate affects the expression of TYMS mRNA CTD PMID:22110744 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of TYMS mRNA CTD PMID:25993096 sunitinib decreases expression ISO RGD:732334 6480464 Sunitinib results in decreased expression of TYMS mRNA CTD PMID:31533062 tanespimycin decreases expression ISO RGD:732334 6480464 tanespimycin results in decreased expression of TYMS protein CTD PMID:18830594 Tegafur affects response to substance ISO RGD:732334 6480464 TYMS promoter polymorphism affects the susceptibility to Tegafur CTD PMID:16617381 temozolomide increases expression ISO RGD:732334 6480464 Temozolomide results in increased expression of TYMS mRNA CTD PMID:31758290 Temsirolimus decreases expression ISO RGD:732334 6480464 temsirolimus results in decreased expression of TYMS mRNA CTD PMID:19764996 testosterone decreases expression ISO RGD:732334 6480464 Testosterone results in decreased expression of TYMS mRNA CTD PMID:21592394 testosterone multiple interactions ISO RGD:732334 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of TYMS mRNA CTD PMID:21592394 tetrachloromethane affects expression ISO RGD:736838 6480464 Carbon Tetrachloride affects the expression of TYMS mRNA CTD PMID:17484886 thapsigargin decreases expression ISO RGD:732334 6480464 Thapsigargin results in decreased expression of TYMS mRNA CTD PMID:22378314 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of TYMS mRNA CTD PMID:23411599 , PMID:34492290 thymidine multiple interactions ISO RGD:736838 6480464 Thymidine inhibits the reaction [Fluorouracil results in decreased expression of TYMS] CTD PMID:9050858 titanium dioxide increases expression ISO RGD:736838 6480464 titanium dioxide results in increased expression of TYMS mRNA CTD PMID:23557971 , PMID:27760801 titanium dioxide multiple interactions ISO RGD:732334 6480464 [Vitallium analog binds to titanium dioxide] which results in decreased expression of TYMS mRNA CTD PMID:23825117 toluene 2,4-diisocyanate increases expression ISO RGD:736838 6480464 Toluene 2, 4-Diisocyanate results in increased expression of TYMS mRNA CTD PMID:21404309 TOMUDEX affects binding EXP 1545055 Tomudex binds to Tyms protein RGD topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of TYMS mRNA CTD PMID:25729387 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of TYMS mRNA CTD PMID:25729387 trichostatin A multiple interactions ISO RGD:732334 6480464 [trichostatin A results in decreased expression of TYMS protein] which results in increased susceptibility to Fluorouracil more ... CTD PMID:17172411 trichostatin A increases degradation ISO RGD:732334 6480464 trichostatin A results in increased degradation of TYMS protein CTD PMID:17172411 trichostatin A decreases expression ISO RGD:732334 6480464 trichostatin A results in decreased expression of TYMS mRNA, trichostatin A results in decreased expression of TYMS protein CTD PMID:17172411 , PMID:19606018 triclosan decreases expression ISO RGD:732334 6480464 Triclosan results in decreased expression of TYMS mRNA CTD PMID:30510588 trimellitic anhydride increases expression ISO RGD:736838 6480464 trimellitic anhydride results in increased expression of TYMS mRNA CTD PMID:19042947 triptonide decreases expression ISO RGD:736838 6480464 triptonide results in decreased expression of TYMS mRNA CTD PMID:33045310 troglitazone decreases expression ISO RGD:732334 6480464 troglitazone results in decreased expression of TYMS mRNA CTD PMID:19140230 tungsten increases expression ISO RGD:736838 6480464 Tungsten results in increased expression of TYMS mRNA CTD PMID:30912803 urethane decreases expression ISO RGD:732334 6480464 Urethane results in decreased expression of TYMS mRNA CTD PMID:28818685 valproic acid decreases expression ISO RGD:732334 6480464 Valproic Acid results in decreased expression of TYMS mRNA CTD PMID:28001369 vincristine affects response to substance ISO RGD:732334 6480464 TYMS gene polymorphism affects the susceptibility to Vincristine CTD PMID:15713801 vorinostat decreases expression ISO RGD:732334 6480464 vorinostat results in decreased expression of TYMS mRNA, vorinostat results in decreased expression of TYMS protein CTD PMID:17172411 , PMID:20072153 wogonin multiple interactions ISO RGD:732334 6480464 [wogonin co-treated with Fluorouracil] results in increased expression of TYMS mRNA CTD PMID:20570612 wogonin increases expression ISO RGD:732334 6480464 wogonin results in increased expression of TYMS mRNA CTD PMID:20570612 zidovudine multiple interactions ISO RGD:732334 6480464 [Zidovudine co-treated with Lamivudine] results in decreased expression of TYMS mRNA CTD PMID:15784690 zinc atom increases expression ISO RGD:732334 6480464 Zinc deficiency results in increased expression of TYMS mRNA CTD PMID:22171008 zinc(0) increases expression ISO RGD:732334 6480464 Zinc deficiency results in increased expression of TYMS mRNA CTD PMID:22171008