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Gene: Xrcc3 (X-ray repair cross complementing 3) Rattus norvegicus
Symbol: Xrcc3
Name: X-ray repair cross complementing 3
RGD ID: 1306849
Description: Predicted to contribute to crossover junction endodeoxyribonuclease activity and four-way junction DNA binding activity. Involved in response to organic substance. Predicted to localize to several cellular components, including nucleus; perinuclear region of cytoplasm; and replication fork. Human ortholog(s) of this gene implicated in breast cancer; familial melanoma; and pancreatic cancer. Orthologous to human XRCC3 (X-ray repair cross complementing 3); PARTICIPATES IN homologous recombination pathway of double-strand break repair; INTERACTS WITH (+)-pilocarpine; amphetamine; chloroethene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA repair protein XRCC3; DNA repair protein XRCC3-like; LOC100359601; LOC102551085; LOC314463; rCG27697-like; X-ray repair complementing defective repair in Chinese hamster cells 3
Homo sapiens (human) : XRCC3 (X-ray repair cross complementing 3)  HGNC  Alliance
Mus musculus (house mouse) : Xrcc3 (X-ray repair complementing defective repair in Chinese hamster cells 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xrcc3 (X-ray repair cross complementing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : XRCC3 (X-ray repair cross complementing 3)
Canis lupus familiaris (dog) : XRCC3 (X-ray repair cross complementing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xrcc3 (X-ray repair cross complementing 3)
Sus scrofa (pig) : XRCC3 (X-ray repair cross complementing 3)
Chlorocebus sabaeus (African green monkey) : XRCC3 (X-ray repair cross complementing 3)
Heterocephalus glaber (naked mole-rat) : Xrcc3 (X-ray repair cross complementing 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06136,366,917 - 136,380,751 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6136,371,555 - 136,379,348 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06145,372,463 - 145,388,673 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46136,594,276 - 136,602,069 (-)NCBIRGSC3.4rn4RGSC3.4
Celera6128,413,783 - 128,427,617 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Xrcc3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306849
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.