Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Kynu (kynureninase) Rattus norvegicus
Analyze
Symbol: Kynu
Name: kynureninase
Description: Exhibits kynureninase activity and pyridoxal phosphate binding activity. Involved in aging and tryptophan catabolic process to acetyl-CoA. Localizes to the cytosol. Used to study hypertension. Orthologous to human KYNU (kynureninase); PARTICIPATES IN tryptophan metabolic pathway; kynurenine metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1-benzylpiperazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: kynureninase (L-kynurenine hydrolase); L-kynurenine hydrolase
Orthologs:
Homo sapiens (human) : KYNU (kynureninase)  HGNC  Alliance
Mus musculus (house mouse) : Kynu (kynureninase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kynu (kynureninase)
Pan paniscus (bonobo/pygmy chimpanzee) : KYNU (kynureninase)
Canis lupus familiaris (dog) : KYNU (kynureninase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kynu (kynureninase)
Sus scrofa (pig) : KYNU (kynureninase)
more info ...
Is Marker For: QTLs:   Bp140  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0328,416,926 - 28,566,939 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl328,416,954 - 28,566,928 (+)Ensembl
Rnor_5.0333,622,141 - 33,770,793 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4324,046,242 - 24,195,898 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1323,942,613 - 24,092,267 (+)NCBI
Celera326,096,675 - 26,244,576 (+)NCBICelera
Cytogenetic Map3q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kynu
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 71061
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.