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Gene: Kynu (kynureninase) Mus musculus
Symbol: Kynu
Name: kynureninase
Description: Predicted to have hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; protein homodimerization activity; and pyridoxal phosphate binding activity. Predicted to be involved in several processes, including aromatic amino acid family metabolic process; pyridine-containing compound biosynthetic process; and response to interferon-gamma. Localizes to the mitochondrion. Orthologous to human KYNU (kynureninase); PARTICIPATES IN kynurenine metabolic pathway; tryptophan metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; buta-1,3-diene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4432411A05Rik; kynureninase (L-kynurenine hydrolase); L-kynurenine hydrolase
Homo sapiens (human) : KYNU (kynureninase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kynu (kynureninase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kynu (kynureninase)
Pan paniscus (bonobo/pygmy chimpanzee) : KYNU (kynureninase)
Canis lupus familiaris (dog) : KYNU (kynureninase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kynu (kynureninase)
Sus scrofa (pig) : KYNU (kynureninase)
Chlorocebus sabaeus (African green monkey) : KYNU (kynureninase)
Heterocephalus glaber (naked mole-rat) : Kynu (kynureninase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl243,555,329 - 43,682,715 (+)EnsemblGRCm38mm10GRCm38
GRCm38243,555,258 - 43,683,048 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37243,410,849 - 43,538,235 (+)NCBIGRCm37mm9NCBIm37
MGSCv36243,377,338 - 43,504,724 (+)NCBImm8
Celera245,275,609 - 45,403,071 (+)NCBICelera
Cytogenetic Map2BNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Kynu
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737184
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.