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Gene: KYNU (kynureninase) Homo sapiens
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Symbol: KYNU
Name: kynureninase
Description: Exhibits 3-hydroxykynureninase activity; kynureninase activity; and protein homodimerization activity. Involved in several processes, including aromatic amino acid family metabolic process; pyridine-containing compound biosynthetic process; and response to interferon-gamma. Localizes to the cytosol; mitochondrion; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: kynureninase (L-kynurenine hydrolase); KYNUU; l-kynurenine hydrolase; VCRL2
Orthologs:
Mus musculus (house mouse) : Kynu (kynureninase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kynu (kynureninase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kynu (kynureninase)
Pan paniscus (bonobo/pygmy chimpanzee) : KYNU (kynureninase)
Canis lupus familiaris (dog) : KYNU (kynureninase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kynu (kynureninase)
Sus scrofa (pig) : KYNU (kynureninase)
Chlorocebus sabaeus (African green monkey) : KYNU (kynureninase)
Heterocephalus glaber (naked mole-rat) : Kynu (kynureninase)
more info ...
Related Pseudogenes: KYNUP1   KYNUP2   KYNUP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2142,877,657 - 143,055,833 (+)EnsemblGRCh38hg38GRCh38
GRCh382142,877,664 - 143,055,833 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372143,506,497 - 143,799,885 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362143,351,665 - 143,516,355 (+)NCBINCBI36hg18NCBI36
Build 342143,468,950 - 143,633,606NCBI
Celera2137,347,656 - 137,512,293 (+)NCBI
Cytogenetic Map2q22.2NCBI
HuRef2135,626,307 - 135,791,074 (+)NCBIHuRef
CHM1_12143,640,202 - 143,804,900 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KYNU
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734173
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.