(-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 [Carbon Tetrachloride co-treated with epigallocatechin gallate] results in decreased expression of IGF1R mRNA CTD PMID:19646978 (-)-epigallocatechin 3-gallate increases expression ISO RGD:68997 6480464 epigallocatechin gallate results in increased expression of IGF1R mRNA CTD PMID:22079256 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:68997 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IGF1R mRNA CTD PMID:22079256 (-)-epigallocatechin 3-gallate decreases expression ISO RGD:68997 6480464 epigallocatechin gallate results in decreased expression of IGF1R protein modified form CTD PMID:20346928 (S)-naringenin multiple interactions ISO RGD:68997 6480464 [naringenin co-treated with bisphenol A] results in increased expression of IGF1R mRNA, [naringenin metabolite co-treated with bisphenol A] results in increased expression of IGF1R mRNA CTD PMID:36235125 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of IGF1R mRNA, Nicotine results in decreased expression of IGF1R protein CTD PMID:20960268 , PMID:22265867 (S)-nicotine affects expression EXP 6480464 Nicotine affects the expression of IGF1R mRNA CTD PMID:31972234 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of IGF1R mRNA CTD PMID:20426880 (Z)-ligustilide decreases phosphorylation ISO RGD:68997 6480464 ligustilide results in decreased phosphorylation of IGF1R protein CTD PMID:23973442 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO RGD:10766 6480464 2 more ... CTD PMID:10965916 1,2-dimethylhydrazine decreases expression EXP 6480464 1, 2-Dimethylhydrazine results in decreased expression of IGF1R mRNA CTD PMID:32387197 1,2-dimethylhydrazine multiple interactions ISO RGD:10766 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of IGF1R mRNA] CTD PMID:22206623 1,2-dimethylhydrazine decreases expression ISO RGD:10766 6480464 1, 2-Dimethylhydrazine results in decreased expression of IGF1R mRNA CTD PMID:22206623 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Triclosan co-treated with Ethinyl Estradiol] results in increased expression of IGF1R mRNA more ... CTD PMID:23261820 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of IGF1R mRNA CTD PMID:23261820 17beta-estradiol multiple interactions ISO RGD:10766 6480464 ESR1 protein promotes the reaction [Estradiol results in decreased expression of IGF1R mRNA], Estradiol affects the reaction [CYP19A1 affects the expression of IGF1R mRNA] CTD PMID:11985600 , PMID:25210133 17beta-estradiol increases phosphorylation ISO RGD:68997 6480464 Estradiol results in increased phosphorylation of IGF1R protein CTD PMID:16024245 , PMID:23094148 17beta-estradiol increases expression ISO RGD:68997 6480464 Estradiol results in increased expression of IGF1R mRNA CTD PMID:11813992 more ... 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of IGF1R mRNA more ... CTD PMID:22465879 , PMID:26496021 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of IGF1R mRNA CTD PMID:20068009 more ... 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of IGF1R mRNA CTD PMID:16522720 17beta-estradiol increases expression ISO RGD:10766 6480464 Estradiol results in increased expression of IGF1R mRNA CTD PMID:17640349 17beta-estradiol multiple interactions ISO RGD:68997 6480464 [Estradiol co-treated with bisphenol A] results in increased expression of IGF1R mRNA more ... CTD PMID:16024245 more ... 17beta-estradiol decreases expression ISO RGD:10766 6480464 Estradiol results in decreased expression of IGF1R mRNA CTD PMID:14664709 , PMID:25210133 17beta-estradiol 17-glucosiduronic acid multiple interactions EXP 6480464 4-(6-bromo-1 more ... CTD PMID:29090346 17beta-estradiol 17-glucosiduronic acid increases phosphorylation EXP 6480464 estradiol-17 beta-glucuronide results in increased phosphorylation of IGF1R protein CTD PMID:29090346 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:68997 6480464 Metribolone results in increased expression of IGF1R mRNA CTD PMID:18586690 , PMID:21440447 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:68997 6480464 Dapsone analog inhibits the reaction [Metribolone results in increased expression of IGF1R mRNA], resveratrol inhibits the reaction [Metribolone results in increased expression of IGF1R mRNA] CTD PMID:18586690 , PMID:21440447 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO RGD:68997 6480464 Masoprocol inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1R mRNA], Masoprocol inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1R protein] CTD PMID:18491370 17beta-hydroxy-5alpha-androstan-3-one multiple interactions EXP 6480464 nilutamide inhibits the reaction [Dihydrotestosterone results in decreased expression of IGF1R protein] CTD PMID:10650946 17beta-hydroxy-5alpha-androstan-3-one decreases expression EXP 6480464 Dihydrotestosterone results in decreased expression of IGF1R protein CTD PMID:10650946 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:68997 6480464 Dihydrotestosterone results in increased expression of IGF1R mRNA, Dihydrotestosterone results in increased expression of IGF1R protein CTD PMID:18491370 , PMID:29581250 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:68997 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2 more ... CTD PMID:33571556 2,2',5,5'-tetrachlorobiphenyl affects expression ISO RGD:68997 6480464 2 more ... CTD PMID:21703328 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:10766 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10766 6480464 [Tetrachlorodibenzodioxin co-treated with EGF protein] results in increased expression of IGF1R mRNA CTD PMID:16054899 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:68997 6480464 Tetrachlorodibenzodioxin results in decreased expression of IGF1R mRNA CTD PMID:23152189 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:68997 6480464 Tetrachlorodibenzodioxin results in increased expression of IGF1R mRNA CTD PMID:17555868 , PMID:22903824 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10766 6480464 Tetrachlorodibenzodioxin results in increased expression of IGF1R mRNA CTD PMID:15034205 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO RGD:68997 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of IGF1R protein CTD PMID:9683191 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10766 6480464 Tetrachlorodibenzodioxin results in decreased expression of IGF1R mRNA CTD PMID:16054899 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2,4-dinitrobenzenesulfonic acid decreases expression ISO RGD:10766 6480464 2, 4-dinitrobenzenesulfonic acid results in decreased expression of IGF1R mRNA CTD PMID:30116771 2-deoxy-D-glucose multiple interactions ISO RGD:68997 6480464 Deoxyglucose results in increased phosphorylation of and results in increased activity of IGF1R protein CTD PMID:23041229 2-hydroxypropanoic acid increases expression ISO RGD:68997 6480464 Lactic Acid results in increased expression of IGF1R mRNA CTD PMID:30851411 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 3-chloropropane-1,2-diol decreases expression ISO RGD:68997 6480464 alpha-Chlorohydrin results in decreased expression of IGF1R mRNA CTD PMID:28070108 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:10766 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of IGF1R mRNA CTD PMID:16054899 4,4'-diaminodiphenylmethane decreases expression ISO RGD:10766 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of IGF1R mRNA CTD PMID:18648102 4-hydroxy-17beta-estradiol increases expression ISO RGD:68997 6480464 4-hydroxyestradiol results in increased expression of IGF1R protein CTD PMID:23685341 4-hydroxynon-2-enal decreases expression ISO RGD:68997 6480464 4-hydroxy-2-nonenal results in decreased expression of IGF1R mRNA CTD PMID:12419474 4-hydroxyphenyl retinamide increases expression ISO RGD:10766 6480464 Fenretinide results in increased expression of IGF1R mRNA CTD PMID:28973697 4-vinylcyclohexene dioxide affects expression ISO RGD:10766 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of IGF1R mRNA CTD PMID:20829426 5,6,7,8-tetrahydrofolic acid decreases expression ISO RGD:68997 6480464 5 more ... CTD PMID:16728583 5-fluorouracil multiple interactions ISO RGD:68997 6480464 Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of IGF1R protein], Fluorouracil results in decreased phosphorylation of and results in decreased activity of IGF1R protein CTD PMID:17918158 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of IGF1R mRNA CTD PMID:30047161 7,9-dihydro-1H-purine-2,6,8(3H)-trione affects abundance ISO RGD:68997 6480464 IGF1R gene SNP affects the abundance of Uric Acid CTD PMID:23263486 acetamide increases expression EXP 6480464 acetamide results in increased expression of IGF1R mRNA CTD PMID:31881176 acetazolamide increases expression ISO RGD:10766 6480464 Acetazolamide results in increased expression of IGF1R mRNA CTD PMID:19274763 afimoxifene multiple interactions ISO RGD:68997 6480464 afimoxifene inhibits the reaction [Estrogens results in increased expression of IGF1R mRNA] CTD PMID:21233418 afimoxifene multiple interactions ISO RGD:10766 6480464 afimoxifene results in increased phosphorylation of and results in increased activity of IGF1R protein, ESR1 protein promotes the reaction [afimoxifene results in increased phosphorylation of and results in increased activity of IGF1R protein] CTD PMID:10965916 afimoxifene decreases response to substance ISO RGD:68997 6480464 IGF1R results in decreased susceptibility to afimoxifene CTD PMID:21233418 afimoxifene increases expression ISO RGD:10766 6480464 afimoxifene results in increased expression of IGF1R mRNA CTD PMID:17640349 aflatoxin B1 increases expression ISO RGD:68997 6480464 Aflatoxin B1 results in increased expression of IGF1R mRNA, Aflatoxin B1 results in increased expression of IGF1R protein CTD PMID:20036727 aflatoxin B1 increases methylation ISO RGD:68997 6480464 Aflatoxin B1 results in increased methylation of IGF1R intron CTD PMID:30157460 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of IGF1R protein modified form CTD PMID:24373827 aflatoxin B1 multiple interactions ISO RGD:68997 6480464 Aflatoxin B1 results in increased expression of and results in increased phosphorylation of IGF1R protein CTD PMID:20036727 aldehydo-D-glucose multiple interactions ISO RGD:68997 6480464 Berberine inhibits the reaction [Glucose results in decreased expression of IGF1R protein] CTD PMID:23954465 aldehydo-D-glucose decreases expression ISO RGD:68997 6480464 Glucose results in decreased expression of IGF1R protein CTD PMID:23954465 aldehydo-D-glucose increases expression ISO RGD:68997 6480464 Glucose results in increased expression of IGF1R mRNA CTD PMID:7826318 all-trans-retinoic acid multiple interactions EXP 6480464 Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF1R mRNA], Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF1R protein] CTD PMID:21433279 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of IGF1R protein CTD PMID:21433279 amino acid multiple interactions ISO RGD:10766 6480464 Amino Acids inhibits the reaction [KL gene mutant form results in decreased expression of IGF1R mRNA], H 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in decreased expression of IGF1R mRNA]] CTD PMID:25309793 amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of IGF1R mRNA CTD PMID:30047161 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of IGF1R mRNA CTD PMID:16483693 androgen antagonist multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA CTD PMID:25607892 AP20187 multiple interactions ISO RGD:68997 6480464 [AP20187 results in increased activity of IGF1R protein mutant form] which results in increased expression of EGR3 mRNA CTD PMID:29330302 aristolochic acid A decreases expression ISO RGD:68997 6480464 aristolochic acid I results in decreased expression of IGF1R mRNA CTD PMID:33212167 Aroclor 1254 decreases expression ISO RGD:10766 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of IGF1R mRNA CTD PMID:23650126 arsane affects methylation ISO RGD:68997 6480464 Arsenic affects the methylation of IGF1R gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:68997 6480464 Arsenic affects the methylation of IGF1R gene CTD PMID:25304211 arsenous acid decreases expression ISO RGD:68997 6480464 Arsenic Trioxide results in decreased expression of IGF1R mRNA CTD PMID:19769630 arsenous acid increases expression ISO RGD:68997 6480464 Arsenic Trioxide results in increased expression of IGF1R mRNA CTD PMID:23911876 arsenous acid affects response to substance ISO RGD:68997 6480464 IGF1R mRNA affects the susceptibility to Arsenic Trioxide CTD PMID:23911876 arsenous acid decreases expression ISO RGD:10766 6480464 Arsenic Trioxide results in decreased expression of IGF1R mRNA CTD PMID:24831965 azathioprine multiple interactions ISO RGD:68997 6480464 Azathioprine inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:23958494 azathioprine decreases expression ISO RGD:68997 6480464 Azathioprine results in decreased expression of IGF1R protein CTD PMID:23958494 benzo[a]pyrene increases phosphorylation ISO RGD:68997 6480464 Benzo(a)pyrene results in increased phosphorylation of IGF1R protein CTD PMID:9683191 benzo[a]pyrene decreases methylation ISO RGD:10766 6480464 Benzo(a)pyrene results in decreased methylation of IGF1R intron CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:68997 6480464 Benzo(a)pyrene results in decreased expression of IGF1R mRNA CTD PMID:20106945 more ... benzo[a]pyrene decreases expression ISO RGD:10766 6480464 Benzo(a)pyrene results in decreased expression of IGF1R mRNA CTD PMID:15034205 , PMID:21803694 benzo[a]pyrene multiple interactions ISO RGD:10766 6480464 AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of IGF1R mRNA] CTD PMID:15034205 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:68997 6480464 7 more ... CTD PMID:19150397 more ... berberine multiple interactions ISO RGD:68997 6480464 Berberine inhibits the reaction [Glucose results in decreased expression of IGF1R protein] CTD PMID:23954465 berberine increases expression ISO RGD:68997 6480464 Berberine results in increased expression of IGF1R protein CTD PMID:23954465 beta-hexachlorocyclohexane increases expression ISO RGD:10766 6480464 beta-hexachlorocyclohexane results in increased expression of IGF1R mRNA CTD PMID:17640349 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:10766 6480464 Diethylhexyl Phthalate results in decreased expression of IGF1R mRNA CTD PMID:29753845 bis(2-ethylhexyl) phthalate affects expression ISO RGD:10766 6480464 Diethylhexyl Phthalate affects the expression of IGF1R mRNA CTD PMID:37059381 bisphenol A multiple interactions ISO RGD:10766 6480464 bisphenol A affects the reaction [CYP19A1 affects the expression of IGF1R mRNA] more ... CTD PMID:10965916 , PMID:11985600 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of IGF1R mRNA CTD PMID:25181051 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA, [bisphenol A co-treated with Estradiol] results in decreased expression of IGF1R mRNA CTD PMID:25607892 , PMID:26496021 bisphenol A increases expression ISO RGD:68997 6480464 bisphenol A analog results in increased expression of IGF1R mRNA, bisphenol A results in increased expression of IGF1R mRNA CTD PMID:23810794 more ... bisphenol A multiple interactions ISO RGD:68997 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of IGF1R gene more ... CTD PMID:23810794 more ... bisphenol A increases methylation ISO RGD:68997 6480464 bisphenol A results in increased methylation of IGF1R gene, bisphenol A results in increased methylation of IGF1R promoter CTD PMID:22576693 , PMID:27271280 bisphenol A decreases expression ISO RGD:68997 6480464 bisphenol A results in decreased expression of IGF1R mRNA CTD PMID:22576693 bisphenol A increases phosphorylation ISO RGD:10766 6480464 bisphenol A results in increased phosphorylation of IGF1R protein CTD PMID:21988766 Bisphenol B increases expression ISO RGD:68997 6480464 bisphenol B results in increased expression of IGF1R mRNA CTD PMID:32387340 BMS-754807 decreases phosphorylation ISO RGD:68997 6480464 BMS 754807 results in decreased phosphorylation of IGF1R protein CTD PMID:24986516 BMS-754807 multiple interactions ISO RGD:68997 6480464 [BMS 754807 co-treated with palbociclib] results in decreased phosphorylation of IGF1R protein CTD PMID:24986516 bortezomib increases response to substance ISO RGD:68997 6480464 IGF1R gene SNP results in increased susceptibility to Bortezomib CTD PMID:20864405 butan-1-ol multiple interactions ISO RGD:68997 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of IGF1R mRNA CTD PMID:29432896 Butylparaben multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA CTD PMID:25607892 cadmium atom multiple interactions ISO RGD:68997 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1R mRNA more ... CTD PMID:35301059 , PMID:9648927 cadmium atom multiple interactions ISO RGD:10766 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1R mRNA, [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IGF1R mRNA CTD PMID:29373603 , PMID:33259630 cadmium atom increases expression ISO RGD:68997 6480464 Cadmium results in increased expression of IGF1R mRNA CTD PMID:24376830 cadmium dichloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of IGF1R protein] CTD PMID:21195169 cadmium dichloride multiple interactions ISO RGD:10766 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1R mRNA, [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IGF1R mRNA CTD PMID:29373603 , PMID:33259630 cadmium dichloride multiple interactions ISO RGD:68997 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1R mRNA more ... CTD PMID:23673518 , PMID:35301059 cadmium dichloride decreases expression ISO RGD:10766 6480464 Cadmium Chloride results in decreased expression of IGF1R mRNA CTD PMID:15501611 cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of IGF1R protein CTD PMID:21195169 caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of IGF1R mRNA, Caffeine results in decreased expression of IGF1R protein CTD PMID:22583948 more ... caffeine affects expression EXP 6480464 Caffeine affects the expression of IGF1R mRNA CTD PMID:29343424 calcitriol affects expression ISO RGD:68997 6480464 Calcitriol affects the expression of IGF1R mRNA CTD PMID:19918113 calcitriol increases expression ISO RGD:68997 6480464 Calcitriol results in increased expression of IGF1R mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:68997 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of IGF1R mRNA CTD PMID:21592394 capsaicin increases expression ISO RGD:68997 6480464 Capsaicin results in increased expression of IGF1R mRNA CTD PMID:21310942 capsaicin multiple interactions ISO RGD:68997 6480464 TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1R mRNA] CTD PMID:21310942 captan decreases expression ISO RGD:10766 6480464 Captan results in decreased expression of IGF1R mRNA CTD PMID:31558096 carbamazepine affects expression ISO RGD:68997 6480464 Carbamazepine affects the expression of IGF1R mRNA CTD PMID:24752500 carbon nanotube decreases expression ISO RGD:10766 6480464 Nanotubes more ... CTD PMID:25554681 Chimaphylin decreases expression ISO RGD:68997 6480464 chimaphilin results in decreased expression of IGF1R protein, chimaphilin results in decreased expression of IGF1R protein modified form CTD PMID:25980584 chitin multiple interactions ISO RGD:68997 6480464 [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of IGF1R mRNA CTD PMID:30041514 chloropicrin increases expression ISO RGD:68997 6480464 chloropicrin results in increased expression of IGF1R mRNA CTD PMID:26352163 chromium(6+) increases expression ISO RGD:68997 6480464 chromium hexavalent ion results in increased expression of IGF1R protein CTD PMID:23748240 chromium(6+) multiple interactions ISO RGD:68997 6480464 MIR143 inhibits the reaction [chromium hexavalent ion results in increased expression of IGF1R protein] CTD PMID:23748240 chrysin multiple interactions EXP 6480464 chrysin inhibits the reaction [Testosterone results in increased expression of IGF1R mRNA] CTD PMID:29247772 cisplatin decreases response to substance ISO RGD:68997 6480464 IGF1R protein results in decreased susceptibility to Cisplatin CTD PMID:21442237 cisplatin decreases expression ISO RGD:68997 6480464 Cisplatin results in decreased expression of IGF1R mRNA CTD PMID:27594783 clodronic acid increases expression ISO RGD:68997 6480464 Clodronic Acid results in increased expression of IGF1R mRNA CTD PMID:25596134 cocaine affects expression EXP 6480464 Cocaine affects the expression of IGF1R mRNA CTD PMID:20187946 copper atom multiple interactions ISO RGD:68997 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of IGF1R protein, [Thiosemicarbazones binds to Copper] which results in decreased phosphorylation of IGF1R protein CTD PMID:20931265 copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of IGF1R protein CTD PMID:15734878 copper(0) multiple interactions ISO RGD:68997 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of IGF1R protein, [Thiosemicarbazones binds to Copper] which results in decreased phosphorylation of IGF1R protein CTD PMID:20931265 copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of IGF1R protein CTD PMID:15734878 corosolic acid multiple interactions ISO RGD:10766 6480464 corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein] CTD PMID:26513295 corticosterone decreases expression EXP 6480464 Corticosterone results in decreased expression of IGF1R mRNA, Corticosterone results in decreased expression of IGF1R protein CTD PMID:12807724 , PMID:29966748 corticosterone multiple interactions EXP 6480464 [IGF2R protein co-treated with IGF1R protein] affects the reaction [IGF2 protein inhibits the reaction [Corticosterone results in decreased expression of SOD2 protein]] CTD PMID:24667322 cortisol affects expression ISO RGD:68997 6480464 Hydrocortisone affects the expression of IGF1R mRNA CTD PMID:30528684 cortisol multiple interactions ISO RGD:68997 6480464 Mifepristone affects the reaction [Hydrocortisone affects the expression of IGF1R mRNA] CTD PMID:30528684 crocidolite asbestos decreases expression ISO RGD:68997 6480464 Asbestos, Crocidolite results in decreased expression of IGF1R mRNA CTD PMID:23634900 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of IGF1R mRNA CTD PMID:26577399 curcumin multiple interactions ISO RGD:68997 6480464 Curcumin inhibits the reaction [IGF1 protein results in increased activity of IGF1R protein] more ... CTD PMID:17499312 , PMID:17918158 curcumin decreases expression ISO RGD:68997 6480464 Curcumin analog results in decreased expression of IGF1R mRNA, Curcumin results in decreased expression of IGF1R mRNA CTD PMID:17499312 , PMID:26409325 cyclosporin A decreases expression ISO RGD:68997 6480464 Cyclosporine results in decreased expression of IGF1R mRNA CTD PMID:25562108 cypermethrin increases expression ISO RGD:68997 6480464 cypermethrin results in increased expression of IGF1R mRNA CTD PMID:27704156 D-glucose increases expression ISO RGD:68997 6480464 Glucose results in increased expression of IGF1R mRNA CTD PMID:7826318 D-glucose multiple interactions ISO RGD:68997 6480464 Berberine inhibits the reaction [Glucose results in decreased expression of IGF1R protein] CTD PMID:23954465 D-glucose decreases expression ISO RGD:68997 6480464 Glucose results in decreased expression of IGF1R protein CTD PMID:23954465 daidzein decreases expression ISO RGD:68997 6480464 daidzein results in decreased expression of IGF1R mRNA CTD PMID:16865672 dapsone multiple interactions ISO RGD:68997 6480464 Dapsone analog inhibits the reaction [Metribolone results in increased expression of IGF1R mRNA] CTD PMID:21440447 DDE multiple interactions ISO RGD:68997 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2 more ... CTD PMID:33571556 deguelin decreases expression ISO RGD:68997 6480464 deguelin metabolite results in decreased expression of IGF1R protein more ... CTD PMID:19139008 , PMID:33512557 dexamethasone multiple interactions ISO RGD:10766 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of IGF1R mRNA CTD PMID:16054899 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of IGF1R mRNA, Dexamethasone results in decreased expression of IGF1R protein CTD PMID:19853640 , PMID:35148621 dexamethasone decreases expression ISO RGD:68997 6480464 Dexamethasone results in decreased expression of IGF1R mRNA CTD PMID:25047013 diarsenic trioxide decreases expression ISO RGD:10766 6480464 Arsenic Trioxide results in decreased expression of IGF1R mRNA CTD PMID:24831965 diarsenic trioxide affects response to substance ISO RGD:68997 6480464 IGF1R mRNA affects the susceptibility to Arsenic Trioxide CTD PMID:23911876 diarsenic trioxide decreases expression ISO RGD:68997 6480464 Arsenic Trioxide results in decreased expression of IGF1R mRNA CTD PMID:19769630 diarsenic trioxide increases expression ISO RGD:68997 6480464 Arsenic Trioxide results in increased expression of IGF1R mRNA CTD PMID:23911876 dibenz[a,h]anthracene decreases expression ISO RGD:10766 6480464 1 more ... CTD PMID:26377693 dibutyl phthalate increases expression ISO RGD:10766 6480464 Dibutyl Phthalate results in increased expression of IGF1R mRNA CTD PMID:21266533 dibutyl phthalate decreases expression ISO RGD:10766 6480464 Dibutyl Phthalate results in decreased expression of IGF1R mRNA CTD PMID:37439711 dibutyl phthalate multiple interactions ISO RGD:10766 6480464 Dibutyl Phthalate results in decreased expression of and results in decreased phosphorylation of IGF1R protein CTD PMID:37439711 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of IGF1R mRNA, Dibutyl Phthalate results in increased expression of IGF1R protein CTD PMID:15829613 diclofenac affects expression ISO RGD:68997 6480464 Diclofenac affects the expression of IGF1R mRNA CTD PMID:24752500 dicrotophos increases expression ISO RGD:68997 6480464 dicrotophos results in increased expression of IGF1R mRNA CTD PMID:28302478 diethylstilbestrol decreases expression ISO RGD:10766 6480464 Diethylstilbestrol results in decreased expression of IGF1R mRNA CTD PMID:15171707 diethylstilbestrol increases phosphorylation ISO RGD:10766 6480464 Diethylstilbestrol results in increased phosphorylation of IGF1R protein CTD PMID:15171707 diethylstilbestrol multiple interactions ISO RGD:10766 6480464 Diethylstilbestrol results in increased phosphorylation of and results in increased activity of IGF1R protein, ESR1 protein promotes the reaction [Diethylstilbestrol results in increased phosphorylation of and results in increased activity of IGF1R protein] CTD PMID:10965916 dihydrofolic acid decreases expression ISO RGD:68997 6480464 dihydrofolate results in decreased expression of IGF1R mRNA CTD PMID:16728583 dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of IGF1R mRNA CTD PMID:17481689 dioxygen multiple interactions EXP 6480464 Tea inhibits the reaction [Oxygen deficiency results in decreased expression of IGF1R protein modified form] CTD PMID:29139225 dioxygen decreases expression EXP 6480464 Oxygen deficiency results in decreased expression of IGF1R protein modified form CTD PMID:29139225 diquat increases response to substance ISO RGD:10766 6480464 IGF1R protein results in increased susceptibility to Diquat CTD PMID:22132081 Doramectin decreases expression EXP 6480464 doramectin results in decreased expression of IGF1R mRNA CTD PMID:35137919 dorsomorphin multiple interactions ISO RGD:68997 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression ISO RGD:10766 6480464 Doxorubicin results in increased expression of IGF1R mRNA CTD PMID:25896364 doxorubicin decreases expression ISO RGD:68997 6480464 Doxorubicin results in decreased expression of IGF1R mRNA CTD PMID:29803840 doxorubicin decreases response to substance ISO RGD:68997 6480464 IGF1R protein results in decreased susceptibility to Doxorubicin CTD PMID:25980584 enzacamene multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA CTD PMID:25607892 enzalutamide decreases expression ISO RGD:68997 6480464 enzalutamide results in decreased expression of IGF1R mRNA CTD PMID:29581250 equol decreases expression ISO RGD:68997 6480464 Equol results in decreased expression of IGF1R mRNA CTD PMID:16865672 ethanol multiple interactions EXP 6480464 [Dietary Fats co-treated with Ethanol] results in increased expression of IGF1R mRNA more ... CTD PMID:19735724 more ... ethanol increases expression ISO RGD:10766 6480464 Ethanol results in increased expression of IGF1R mRNA CTD PMID:30319688 ethanol affects expression ISO RGD:10766 6480464 Ethanol affects the expression of IGF1R mRNA CTD PMID:30319688 ethanol decreases expression ISO RGD:10766 6480464 Ethanol results in decreased expression of IGF1R mRNA CTD PMID:29524503 ethanol decreases expression ISO RGD:68997 6480464 Ethanol results in decreased expression of IGF1R mRNA, Ethanol results in decreased expression of IGF1R protein modified form CTD PMID:29524503 , PMID:31226463 ethanol affects expression EXP 6480464 Ethanol affects the expression of IGF1R mRNA, Ethanol affects the expression of IGF1R protein CTD PMID:31039417 , PMID:32535229 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of IGF1R mRNA, Ethanol results in decreased expression of IGF1R protein modified form CTD PMID:31226463 ethanol increases activity EXP 6480464 Ethanol results in increased activity of IGF1R protein CTD PMID:19735724 ethyl methanesulfonate increases expression ISO RGD:68997 6480464 Ethyl Methanesulfonate results in increased expression of IGF1R mRNA CTD PMID:23649840 etoposide affects response to substance ISO RGD:68997 6480464 IGF1R protein affects the susceptibility to Etoposide CTD PMID:15499378 everolimus multiple interactions ISO RGD:68997 6480464 platycodin D inhibits the reaction [Everolimus results in increased expression of IGF1R protein] CTD PMID:28711525 everolimus increases expression ISO RGD:68997 6480464 Everolimus results in increased expression of IGF1R mRNA, Everolimus results in increased expression of IGF1R protein CTD PMID:28711525 fenpyroximate decreases expression ISO RGD:68997 6480464 fenpyroximate results in decreased expression of IGF1R mRNA CTD PMID:33512557 fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of IGF1R mRNA CTD PMID:30307764 folic acid multiple interactions ISO RGD:68997 6480464 Folic Acid inhibits the reaction [IGF1R protein results in increased phosphorylation of MAPK1 protein] more ... CTD PMID:16728583 folic acid multiple interactions ISO RGD:10766 6480464 Folic Acid inhibits the reaction [1 more ... CTD PMID:22206623 , PMID:29068127 folic acid decreases expression ISO RGD:68997 6480464 Folic Acid results in decreased expression of IGF1R mRNA, Folic Acid results in decreased expression of IGF1R protein CTD PMID:16728583 folpet decreases expression ISO RGD:10766 6480464 folpet results in decreased expression of IGF1R mRNA CTD PMID:31558096 formaldehyde increases expression ISO RGD:68997 6480464 Formaldehyde results in increased expression of IGF1R mRNA CTD PMID:23649840 fructose increases expression EXP 6480464 Fructose results in increased expression of IGF1R protein CTD PMID:30480462 fulvestrant multiple interactions ISO RGD:68997 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of IGF1R gene more ... CTD PMID:19815064 more ... fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [[Triclosan co-treated with Ethinyl Estradiol] results in increased expression of IGF1R mRNA], fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of IGF1R mRNA] CTD PMID:23261820 fulvestrant increases phosphorylation ISO RGD:68997 6480464 fulvestrant results in increased phosphorylation of IGF1R protein CTD PMID:19815064 gallic acid increases expression ISO RGD:68997 6480464 Gallic Acid results in increased expression of IGF1R mRNA CTD PMID:34408198 gefitinib multiple interactions ISO RGD:68997 6480464 gefitinib promotes the reaction [IGF1R protein binds to EGFR protein], tyrphostin AG 1024 inhibits the reaction [gefitinib results in increased phosphorylation of IGF1R protein] CTD PMID:17473213 gefitinib increases phosphorylation ISO RGD:68997 6480464 gefitinib results in increased phosphorylation of IGF1R protein CTD PMID:17473213 gemcitabine decreases expression ISO RGD:68997 6480464 Gemcitabine results in decreased expression of IGF1R mRNA CTD PMID:20103597 genistein decreases expression ISO RGD:68997 6480464 Genistein results in decreased expression of IGF1R mRNA CTD PMID:16865672 genistein increases expression ISO RGD:10766 6480464 Genistein results in increased expression of IGF1R mRNA CTD PMID:32186404 genistein multiple interactions ISO RGD:68997 6480464 Genistein inhibits the reaction [bisphenol A results in increased expression of IGF1R mRNA], Genistein inhibits the reaction [Estradiol results in increased expression of IGF1R mRNA] CTD PMID:23933164 genistein increases expression EXP 6480464 Genistein results in increased expression of IGF1R mRNA, Genistein results in increased expression of IGF1R protein CTD PMID:16443925 , PMID:17049845 genistein multiple interactions EXP 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of IGF1R mRNA more ... CTD PMID:11896288 , PMID:16443925 genistein multiple interactions ISO RGD:10766 6480464 ESR1 protein promotes the reaction [Genistein results in increased phosphorylation of and results in increased activity of IGF1R protein], Genistein results in increased phosphorylation of and results in increased activity of IGF1R protein CTD PMID:10965916 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of IGF1R mRNA CTD PMID:22061828 Ginkgoic acid decreases expression ISO RGD:68997 6480464 ginkgolic acid results in decreased expression of IGF1R protein CTD PMID:33508304 Ginkgoic acid multiple interactions ISO RGD:68997 6480464 ginkgolic acid affects the localization of and results in decreased sumoylation of IGF1R protein CTD PMID:33508304 glucose increases expression ISO RGD:68997 6480464 Glucose results in increased expression of IGF1R mRNA CTD PMID:7826318 glucose multiple interactions ISO RGD:68997 6480464 Berberine inhibits the reaction [Glucose results in decreased expression of IGF1R protein] CTD PMID:23954465 glucose decreases expression ISO RGD:68997 6480464 Glucose results in decreased expression of IGF1R protein CTD PMID:23954465 gold atom multiple interactions ISO RGD:68997 6480464 Gold inhibits the reaction [IGF1 protein binds to IGF1R protein], Gold inhibits the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927 gold(0) multiple interactions ISO RGD:68997 6480464 Gold inhibits the reaction [IGF1 protein binds to IGF1R protein], Gold inhibits the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927 herbicide decreases expression EXP 6480464 Herbicides results in decreased expression of IGF1R mRNA CTD PMID:32360609 hexachlorobenzene increases expression EXP 6480464 Hexachlorobenzene results in increased expression of IGF1R protein CTD PMID:16237195 hexachlorobenzene multiple interactions ISO RGD:68997 6480464 [Hexachlorobenzene co-treated with Estradiol] results in increased expression of IGF1R protein more ... CTD PMID:19879930 , PMID:33571556 hexachlorobenzene increases expression ISO RGD:68997 6480464 Hexachlorobenzene results in increased expression of IGF1R protein CTD PMID:19879930 hexachlorobenzene multiple interactions EXP 6480464 Hexachlorobenzene inhibits the reaction [Methylnitrosourea results in increased expression of IGF1R protein] CTD PMID:16237195 hydrogen peroxide decreases response to substance ISO RGD:10766 6480464 IGF1R gene mutant form results in decreased susceptibility to Hydrogen Peroxide CTD PMID:15761239 Indeno[1,2,3-cd]pyrene increases expression ISO RGD:68997 6480464 indeno(1 more ... CTD PMID:32251684 indometacin increases expression EXP 6480464 Indomethacin results in increased expression of IGF1R mRNA CTD PMID:18299717 isoflurane decreases phosphorylation EXP 6480464 Isoflurane results in decreased phosphorylation of IGF1R protein CTD PMID:25597859 isoprenaline increases expression ISO RGD:10766 6480464 Isoproterenol results in increased expression of IGF1R mRNA CTD PMID:20003209 L-ascorbic acid increases expression ISO RGD:10766 6480464 Ascorbic Acid results in increased expression of IGF1R protein CTD PMID:20530736 leuprolide multiple interactions ISO RGD:68997 6480464 Leuprolide results in decreased expression of and results in decreased phosphorylation of IGF1R protein CTD PMID:17143537 linuron decreases expression EXP 6480464 Linuron results in decreased expression of IGF1R mRNA CTD PMID:12730624 lipopolysaccharide multiple interactions EXP 6480464 Honghua extract more ... CTD PMID:31486215 , PMID:31714667 lovastatin multiple interactions EXP 6480464 Lovastatin promotes the reaction [INS protein results in increased phosphorylation of IGF1R protein] CTD PMID:19741129 lycopene decreases expression ISO RGD:68997 6480464 lycopene results in decreased expression of IGF1R protein CTD PMID:17337101 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of IGF1R protein CTD PMID:21402727 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of IGF1R mRNA CTD PMID:19276553 maslinic acid multiple interactions ISO RGD:10766 6480464 maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein] CTD PMID:26513295 masoprocol multiple interactions ISO RGD:68997 6480464 Masoprocol inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1R mRNA] more ... CTD PMID:18491370 , PMID:18645000 masoprocol decreases activity ISO RGD:68997 6480464 Masoprocol results in decreased activity of IGF1R protein CTD PMID:18491370 melatonin decreases expression EXP 156430315 melatonin decreases expression of Igf1r RNA in pulmonary artery smooth muscle cells RGD menadione affects expression ISO RGD:68997 6480464 Vitamin K 3 affects the expression of IGF1R mRNA CTD PMID:20044591 metformin multiple interactions ISO RGD:68997 6480464 [Metformin co-treated with IGF1 protein] results in decreased expression of IGF1R mRNA more ... CTD PMID:21664031 metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [Testosterone results in increased expression of IGF1R mRNA] more ... CTD PMID:26492952 , PMID:36547818 methcathinone increases expression ISO RGD:68997 6480464 monomethylpropion results in increased expression of IGF1R mRNA CTD PMID:22303338 methimazole increases expression ISO RGD:10766 6480464 Methimazole results in increased expression of IGF1R mRNA CTD PMID:29990518 methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of IGF1R mRNA CTD PMID:30047161 methimazole decreases expression ISO RGD:68997 6480464 Methimazole results in decreased expression of IGF1R mRNA CTD PMID:29990518 methoxychlor multiple interactions EXP 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of IGF1R mRNA more ... CTD PMID:11896288 , PMID:16443925 methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of IGF1R gene CTD PMID:35440735 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of IGF1R gene CTD PMID:23303685 methoxychlor decreases expression EXP 6480464 Methoxychlor results in decreased expression of IGF1R mRNA CTD PMID:23303685 methoxychlor increases expression EXP 6480464 Methoxychlor results in increased expression of IGF1R mRNA, Methoxychlor results in increased expression of IGF1R protein CTD PMID:16443925 methyl methanesulfonate increases expression ISO RGD:68997 6480464 Methyl Methanesulfonate results in increased expression of IGF1R mRNA CTD PMID:23649840 methylarsonic acid increases expression EXP 6480464 monomethylarsonic acid results in increased expression of IGF1R mRNA CTD PMID:17481689 methylmercury chloride affects expression EXP 6480464 methylmercuric chloride affects the expression of IGF1R mRNA CTD PMID:20864626 methylmercury chloride multiple interactions ISO RGD:68997 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGF1R mRNA CTD PMID:27188386 methylmercury chloride increases expression ISO RGD:68997 6480464 methylmercuric chloride results in increased expression of IGF1R mRNA CTD PMID:23179753 , PMID:26272509 mifepristone multiple interactions ISO RGD:68997 6480464 Mifepristone affects the reaction [Hydrocortisone affects the expression of IGF1R mRNA] CTD PMID:30528684 mitoxantrone affects response to substance ISO RGD:68997 6480464 IGF1R protein affects the susceptibility to Mitoxantrone CTD PMID:15499378 monocrotaline increases expression EXP 156430315 monocrotaline increases expression of Igf1r RNA in pulmonary artery smooth muscle cells RGD monocrotaline multiple interactions EXP 156430315 melatonin inhibits the reaction [monocrotaline increases expression of Igf1r RNA in pulmonary artery smooth muscle cells] RGD monosodium L-glutamate increases expression EXP 6480464 Sodium Glutamate results in increased expression of IGF1R mRNA CTD PMID:7711889 monosodium L-glutamate multiple interactions ISO RGD:10766 6480464 [Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of IGF1R mRNA, Sodium Glutamate affects the reaction [Azoxymethane affects the expression of IGF1R mRNA] CTD PMID:19001666 , PMID:22223845 monosodium L-glutamate multiple interactions EXP 6480464 GH1 protein inhibits the reaction [Sodium Glutamate results in increased expression of IGF1R mRNA] CTD PMID:7711889 Myrtucommulone A decreases expression ISO RGD:10766 6480464 myrtucommulone A results in decreased expression of IGF1R mRNA CTD PMID:26032814 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions EXP 6480464 N more ... CTD PMID:14644152 N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in decreased methylation of IGF1R gene CTD PMID:33148267 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of IGF1R protein] CTD PMID:21195169 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:68997 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of IGF1R protein] CTD PMID:28711525 N-ethyl-N-nitrosourea increases mutagenesis ISO RGD:10766 6480464 Ethylnitrosourea results in increased mutagenesis of IGF1R gene CTD PMID:16461637 N-ethyl-N-nitrosourea increases phosphorylation ISO RGD:10766 6480464 Ethylnitrosourea results in increased phosphorylation of IGF1R protein CTD PMID:32902906 N-methyl-4-phenylpyridinium decreases expression ISO RGD:68997 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of IGF1R protein CTD PMID:26364587 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:68997 6480464 INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of IGF1R protein] CTD PMID:26364587 N-methyl-N-nitrosourea multiple interactions EXP 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of IGF1R mRNA more ... CTD PMID:16237195 , PMID:22465879 N-methyl-N-nitrosourea increases expression EXP 6480464 Methylnitrosourea results in increased expression of IGF1R protein CTD PMID:16237195 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of IGF1R mRNA CTD PMID:19542621 N-nitrosodiethylamine multiple interactions EXP 6480464 [Mastic Resin co-treated with Diethylnitrosamine] results in decreased expression of IGF1R mRNA CTD PMID:18977376 N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of IGF1R protein CTD PMID:21411721 nickel atom decreases expression ISO RGD:68997 6480464 Nickel results in decreased expression of IGF1R mRNA CTD PMID:25583101 nickel subsulfide affects expression EXP 6480464 nickel subsulfide affects the expression of IGF1R mRNA CTD PMID:24952340 niclosamide affects response to substance ISO RGD:68997 6480464 IGF1R protein affects the susceptibility to Niclosamide CTD PMID:27497986 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of IGF1R mRNA, Nicotine results in decreased expression of IGF1R protein CTD PMID:20960268 , PMID:22265867 nicotine affects expression EXP 6480464 Nicotine affects the expression of IGF1R mRNA CTD PMID:31972234 nicotine increases expression EXP 6480464 Nicotine results in increased expression of IGF1R mRNA CTD PMID:20426880 nilutamide multiple interactions EXP 6480464 nilutamide inhibits the reaction [Dihydrotestosterone results in decreased expression of IGF1R protein] CTD PMID:10650946 nitrofen multiple interactions EXP 6480464 Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF1R mRNA], Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF1R protein] CTD PMID:21433279 nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of IGF1R mRNA, nitrofen results in decreased expression of IGF1R protein CTD PMID:20620343 , PMID:21433279 nitrogen mustard affects response to substance ISO RGD:68997 6480464 IGF1R protein affects the susceptibility to Nitrogen Mustard Compounds CTD PMID:15499378 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of IGF1R protein CTD PMID:17651772 Octicizer decreases phosphorylation ISO RGD:68997 6480464 2-ethylhexyldiphenylphosphate results in decreased phosphorylation of IGF1R protein CTD PMID:35503735 Octicizer decreases phosphorylation ISO RGD:10766 6480464 2-ethylhexyldiphenylphosphate results in decreased phosphorylation of IGF1R protein CTD PMID:35503735 Octicizer multiple interactions ISO RGD:68997 6480464 2-ethylhexyldiphenylphosphate results in decreased activity of and results in decreased phosphorylation of IGF1R protein CTD PMID:35503735 Octicizer affects binding ISO RGD:68997 6480464 2-ethylhexyldiphenylphosphate binds to IGF1R protein CTD PMID:35503735 ozone increases expression EXP 6480464 Ozone results in increased expression of IGF1R mRNA CTD PMID:16330353 p-menthan-3-ol decreases expression ISO RGD:68997 6480464 Menthol results in decreased expression of IGF1R mRNA CTD PMID:26760959 palbociclib multiple interactions ISO RGD:68997 6480464 [BMS 754807 co-treated with palbociclib] results in decreased phosphorylation of IGF1R protein CTD PMID:24986516 paracetamol affects expression ISO RGD:10766 6480464 Acetaminophen affects the expression of IGF1R mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of IGF1R mRNA CTD PMID:33387578 paracetamol multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA CTD PMID:25607892 paraquat affects response to substance ISO RGD:10766 6480464 IGF1R protein affects the susceptibility to Paraquat CTD PMID:23898955 paraquat multiple interactions ISO RGD:10766 6480464 Paraquat results in increased expression of and results in increased phosphorylation of IGF1R protein CTD PMID:23898955 perfluorododecanoic acid decreases expression EXP 6480464 perfluorododecanoic acid results in decreased expression of IGF1R mRNA CTD PMID:19397962 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:68997 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2 more ... CTD PMID:33571556 perfluorooctanoic acid multiple interactions ISO RGD:68997 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2 more ... CTD PMID:33571556 permethrin multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in decreased methylation of IGF1R gene CTD PMID:33148267 phenobarbital affects expression ISO RGD:10766 6480464 Phenobarbital affects the expression of IGF1R mRNA CTD PMID:23091169 phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:10766 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein CTD PMID:26513295 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:10766 6480464 corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein], maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein] CTD PMID:26513295 picolinic acid multiple interactions EXP 6480464 picolinic acid promotes the reaction [INS1 protein results in increased expression of IGF1R mRNA] CTD PMID:20013160 picoxystrobin decreases expression ISO RGD:68997 6480464 picoxystrobin results in decreased expression of IGF1R mRNA CTD PMID:33512557 picropodophyllotoxin multiple interactions ISO RGD:10766 6480464 picropodophyllin binds to and results in decreased activity of IGF1R protein CTD PMID:21371294 picropodophyllotoxin multiple interactions ISO RGD:68997 6480464 [picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein], [picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein] CTD PMID:23673518 picropodophyllotoxin decreases activity ISO RGD:68997 6480464 picropodophyllin results in decreased activity of IGF1R protein CTD PMID:16166596 piperine affects binding ISO RGD:68997 6480464 piperine binds to IGF1R protein CTD PMID:28341137 platycodin D multiple interactions ISO RGD:68997 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of IGF1R protein], platycodin D inhibits the reaction [Everolimus results in increased expression of IGF1R protein] CTD PMID:28711525 platycodin D decreases expression ISO RGD:68997 6480464 platycodin D results in decreased expression of IGF1R protein CTD PMID:28711525 potassium chromate multiple interactions ISO RGD:68997 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IGF1R mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:68997 6480464 potassium chromate(VI) results in decreased expression of IGF1R mRNA CTD PMID:22079256 progesterone decreases expression ISO RGD:68997 6480464 Progesterone results in decreased expression of IGF1R mRNA CTD PMID:18070364 progesterone increases expression EXP 6480464 Progesterone results in increased expression of IGF1R mRNA CTD PMID:19853640 progesterone multiple interactions EXP 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of IGF1R mRNA, [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of IGF1R protein CTD PMID:22465879 propiconazole decreases expression EXP 6480464 propiconazole results in decreased expression of IGF1R mRNA CTD PMID:30047161 pyrimidifen decreases expression ISO RGD:68997 6480464 pyrimidifen results in decreased expression of IGF1R mRNA CTD PMID:33512557 quercetin decreases expression ISO RGD:68997 6480464 Quercetin results in decreased expression of IGF1R mRNA, Quercetin results in decreased expression of IGF1R protein CTD PMID:12653748 more ... quercetin multiple interactions ISO RGD:10766 6480464 Quercetin inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:24353828 quercetin multiple interactions ISO RGD:68997 6480464 Quercetin affects the reaction [[Fatty Acids co-treated with INS protein] affects the phosphorylation of IGF1R protein] CTD PMID:24648896 quercitrin affects expression ISO RGD:68997 6480464 quercitrin affects the expression of IGF1R mRNA CTD PMID:25193878 rac-lactic acid increases expression ISO RGD:68997 6480464 Lactic Acid results in increased expression of IGF1R mRNA CTD PMID:30851411 resveratrol multiple interactions ISO RGD:68997 6480464 resveratrol inhibits the reaction [bisphenol A results in increased expression of IGF1R mRNA] more ... CTD PMID:18586690 more ... resveratrol multiple interactions ISO RGD:10766 6480464 resveratrol inhibits the reaction [IGF1 protein binds to and results in increased phosphorylation of and results in increased activity of IGF1R protein] CTD PMID:24782617 resveratrol increases expression ISO RGD:10766 6480464 resveratrol results in increased expression of IGF1R mRNA, resveratrol results in increased expression of IGF1R protein CTD PMID:17675339 more ... resveratrol decreases phosphorylation ISO RGD:68997 6480464 resveratrol results in decreased phosphorylation of IGF1R protein CTD PMID:26394120 resveratrol increases expression EXP 6480464 resveratrol results in increased expression of IGF1R mRNA CTD PMID:23848300 resveratrol decreases expression ISO RGD:68997 6480464 resveratrol results in decreased expression of IGF1R mRNA, resveratrol results in decreased expression of IGF1R protein CTD PMID:18586690 more ... RU 58668 affects expression ISO RGD:68997 6480464 RU 58668 affects the expression of IGF1R protein CTD PMID:15868441 rutin multiple interactions ISO RGD:68997 6480464 Rutin results in increased susceptibility to [Vitamin E results in decreased expression of IGF1R protein] CTD PMID:20015448 SB 431542 multiple interactions ISO RGD:68997 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Se-methyl-L-selenocysteine increases expression ISO RGD:68997 6480464 selenomethylselenocysteine results in increased expression of IGF1R mRNA CTD PMID:18514395 Se-methylselenocysteine increases expression ISO RGD:68997 6480464 selenomethylselenocysteine results in increased expression of IGF1R mRNA CTD PMID:18514395 simvastatin decreases expression ISO RGD:68997 6480464 Simvastatin results in decreased expression of IGF1R more ... CTD PMID:17158816 , PMID:18489904 simvastatin multiple interactions ISO RGD:10766 6480464 [Simvastatin co-treated with NVP-AEW541] inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein], Simvastatin inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:27734117 simvastatin increases expression ISO RGD:10766 6480464 Simvastatin results in increased expression of IGF1R protein alternative form CTD PMID:17327694 sirolimus affects activity ISO RGD:68997 6480464 Sirolimus affects the activity of IGF1R protein CTD PMID:16227402 sirolimus multiple interactions ISO RGD:68997 6480464 Sirolimus promotes the reaction [IGF1R protein binds to and results in increased phosphorylation of IRS1 protein] CTD PMID:16227402 sirtinol decreases expression ISO RGD:68997 6480464 sirtinol results in decreased expression of IGF1R mRNA CTD PMID:22495798 sodium arsenate increases expression ISO RGD:10766 6480464 sodium arsenate results in increased expression of IGF1R mRNA CTD PMID:21795629 sodium arsenite decreases expression ISO RGD:68997 6480464 sodium arsenite results in decreased expression of IGF1R mRNA CTD PMID:25879800 sodium arsenite increases expression ISO RGD:10766 6480464 sodium arsenite results in increased expression of IGF1R mRNA CTD PMID:17077188 sodium dichromate decreases expression ISO RGD:10766 6480464 sodium bichromate results in decreased expression of IGF1R mRNA CTD PMID:31558096 sophoraflavanone B increases expression EXP 6480464 8-prenylnaringenin results in increased expression of IGF1R mRNA CTD PMID:16522720 sorafenib decreases expression ISO RGD:68997 6480464 sorafenib results in decreased expression of IGF1R mRNA CTD PMID:26409325 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of IGF1R protein CTD PMID:23562514 streptozocin multiple interactions ISO RGD:10766 6480464 [Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein CTD PMID:30721768 streptozocin multiple interactions EXP 6480464 [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA more ... CTD PMID:23562514 , PMID:36547818 succimer multiple interactions ISO RGD:68997 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of IGF1R mRNA CTD PMID:26378955 sucrose multiple interactions EXP 6480464 [Dietary Fats co-treated with Sucrose] results in decreased expression of IGF1R protein, gamma-sitosterol inhibits the reaction [[Dietary Fats co-treated with Sucrose] results in decreased expression of IGF1R protein] CTD PMID:30461321 sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of IGF1R mRNA CTD PMID:30047161 sunitinib increases expression ISO RGD:68997 6480464 Sunitinib results in increased expression of IGF1R mRNA CTD PMID:31533062 tamoxifen increases expression ISO RGD:10766 6480464 Tamoxifen results in increased expression of IGF1R mRNA CTD PMID:21138602 tanespimycin affects expression ISO RGD:68997 6480464 tanespimycin affects the expression of IGF1R protein CTD PMID:22810956 tanespimycin decreases expression EXP 6480464 tanespimycin results in decreased expression of IGF1R protein CTD PMID:22810956 tebufenpyrad decreases expression ISO RGD:68997 6480464 4-chloro-N-((4-(1, 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of IGF1R mRNA CTD PMID:33512557 tert-butyl hydroperoxide decreases expression ISO RGD:68997 6480464 tert-Butylhydroperoxide results in decreased expression of IGF1R mRNA CTD PMID:12419474 testosterone multiple interactions ISO RGD:68997 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of IGF1R mRNA CTD PMID:21592394 testosterone multiple interactions EXP 6480464 chrysin inhibits the reaction [Testosterone results in increased expression of IGF1R mRNA], Metformin inhibits the reaction [Testosterone results in increased expression of IGF1R mRNA] CTD PMID:26492952 , PMID:29247772 testosterone increases expression EXP 6480464 Testosterone results in increased expression of IGF1R mRNA CTD PMID:26492952 , PMID:29247772 testosterone increases expression ISO RGD:68997 6480464 Testosterone results in increased expression of IGF1R mRNA CTD PMID:21592394 testosterone increases expression ISO RGD:10766 6480464 Testosterone results in increased expression of IGF1R mRNA CTD PMID:21045173 testosterone enanthate increases expression EXP 6480464 testosterone enanthate results in increased expression of IGF1R mRNA CTD PMID:23085480 tetrachloromethane multiple interactions EXP 6480464 [Carbon Tetrachloride co-treated with epigallocatechin gallate] results in decreased expression of IGF1R mRNA, IL10 protein affects the reaction [Carbon Tetrachloride results in increased expression of IGF1R protein] CTD PMID:12800242 , PMID:19646978 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of IGF1R mRNA, Carbon Tetrachloride results in increased expression of IGF1R protein CTD PMID:12800242 , PMID:27350269 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of IGF1R mRNA CTD PMID:17805973 tetrathiomolybdate(2-) multiple interactions ISO RGD:68997 6480464 tetrathiomolybdate inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:18480265 thyroxine multiple interactions EXP 6480464 Vitamin E inhibits the reaction [Thyroxine results in increased expression of IGF1R protein] CTD PMID:17447016 thyroxine increases expression EXP 6480464 Thyroxine results in increased expression of IGF1R protein CTD PMID:17447016 trichostatin A decreases expression ISO RGD:68997 6480464 trichostatin A results in decreased expression of IGF1R mRNA CTD PMID:28542535 triclosan multiple interactions EXP 6480464 [Triclosan co-treated with Ethinyl Estradiol] results in increased expression of IGF1R mRNA, fulvestrant inhibits the reaction [[Triclosan co-treated with Ethinyl Estradiol] results in increased expression of IGF1R mRNA] CTD PMID:23261820 triphenyl phosphate increases expression ISO RGD:10766 6480464 triphenyl phosphate results in increased expression of IGF1R mRNA CTD PMID:29316351 tunicamycin decreases expression ISO RGD:10766 6480464 Tunicamycin results in decreased expression of IGF1R mRNA CTD PMID:17127020 valproic acid affects expression ISO RGD:10766 6480464 Valproic Acid affects the expression of IGF1R mRNA CTD PMID:17292431 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of IGF1R mRNA CTD PMID:29427782 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of IGF1R mRNA CTD PMID:29427782 valproic acid multiple interactions ISO RGD:68997 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGF1R mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:68997 6480464 Valproic Acid results in increased expression of IGF1R mRNA CTD PMID:23179753 more ... valproic acid increases methylation ISO RGD:68997 6480464 Valproic Acid results in increased methylation of IGF1R gene CTD PMID:29154799 valproic acid affects expression ISO RGD:68997 6480464 Valproic Acid affects the expression of IGF1R mRNA CTD PMID:25979313 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of IGF1R mRNA CTD PMID:23555832 vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of IGF1R gene CTD PMID:31682807 vitamin E multiple interactions ISO RGD:68997 6480464 Rutin results in increased susceptibility to [Vitamin E results in decreased expression of IGF1R protein] CTD PMID:20015448 vitamin E multiple interactions EXP 6480464 Vitamin E inhibits the reaction [Thyroxine results in increased expression of IGF1R protein] CTD PMID:17447016 vitamin E decreases expression ISO RGD:68997 6480464 Vitamin E results in decreased expression of IGF1R mRNA, Vitamin E results in decreased expression of IGF1R protein CTD PMID:19244175 , PMID:20015448 zinc atom affects expression EXP 6480464 Zinc affects the expression of IGF1R mRNA CTD PMID:16413754 zinc atom multiple interactions ISO RGD:68997 6480464 Zinc promotes the reaction [IGF1 protein binds to IGF1R protein], Zinc promotes the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927 zinc atom decreases expression ISO RGD:68997 6480464 Zinc results in decreased expression of IGF1R protein CTD PMID:19913001 zinc atom increases phosphorylation EXP 6480464 Zinc results in increased phosphorylation of IGF1R protein CTD PMID:14644152 zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of IGF1R mRNA, Zinc deficiency results in decreased expression of IGF1R protein CTD PMID:21893222 zinc sulfate multiple interactions ISO RGD:68997 6480464 IGF1R mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein] more ... CTD PMID:19946718 zinc(0) affects expression EXP 6480464 Zinc affects the expression of IGF1R mRNA CTD PMID:16413754 zinc(0) increases phosphorylation EXP 6480464 Zinc results in increased phosphorylation of IGF1R protein CTD PMID:14644152 zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of IGF1R mRNA, Zinc deficiency results in decreased expression of IGF1R protein CTD PMID:21893222 zinc(0) decreases expression ISO RGD:68997 6480464 Zinc results in decreased expression of IGF1R protein CTD PMID:19913001 zinc(0) multiple interactions ISO RGD:68997 6480464 Zinc promotes the reaction [IGF1 protein binds to IGF1R protein], Zinc promotes the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927
