Gene: Cdkn2b (cyclin-dependent kinase inhibitor 2B) Rattus norvegicus
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Symbol: Cdkn2b
Name: cyclin-dependent kinase inhibitor 2B
Description: ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase inhibitor activity (ortholog); protein kinase binding (ortholog); INVOLVED IN aging; cellular response to transforming growth factor beta stimulus; liver development; PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; small cell lung carcinoma pathway; ASSOCIATED WITH endometrial cancer; Mesothelioma; renal cell carcinoma; FOUND IN nucleus; cytoplasm (ortholog); INTERACTS WITH 2-acetamidofluorene; 7,12-dimethyltetraphene; aflatoxin B1
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cyclin dependent kinase inhibitor 2B; Cyclin dependent kinase inhibitor 2B (p15 inhibits CDK4); Cyclin dependent kinase inhibitor 2B (p15, inhibits CDK4); cyclin-dependent kinase 4 inhibitor B; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); p14-INK4b; p15; p15-INK4b
Orthologs:
Homo sapiens (human) : CDKN2B (cyclin dependent kinase inhibitor 2B)  HGNC  Alliance
Mus musculus (house mouse) : Cdkn2b (cyclin dependent kinase inhibitor 2B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdkn2b (cyclin dependent kinase inhibitor 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : CDKN2B (cyclin dependent kinase inhibitor 2B)
Canis lupus familiaris (dog) : CDKN2B (cyclin dependent kinase inhibitor 2B)
Sus scrofa (pig) : CDKN2B (cyclin dependent kinase inhibitor 2B)
more info ...
Is Marker For: QTLs:   Tcas11  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05107,834,353 - 107,857,428 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05111,817,188 - 111,826,334 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45108,939,669 - 108,945,293 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15108,946,492 - 108,950,551 (-)NCBI
Celera5102,728,741 - 102,734,427 (-)NCBICelera
Cytogenetic Map5q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cdkn2b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2324
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE