Gene: Cdkn2b (cyclin-dependent kinase inhibitor 2B) Rattus norvegicus
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Symbol: Cdkn2b
Name: cyclin-dependent kinase inhibitor 2B
Description: ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase inhibitor activity (ortholog); protein kinase binding (ortholog); INVOLVED IN aging; cellular response to transforming growth factor beta stimulus; liver development; PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; small cell lung carcinoma pathway; ASSOCIATED WITH endometrial cancer; Mesothelioma; renal cell carcinoma; FOUND IN nucleus; cytoplasm (ortholog); INTERACTS WITH 2-acetamidofluorene; 7,12-dimethyltetraphene; aflatoxin B1
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cyclin dependent kinase inhibitor 2B; Cyclin dependent kinase inhibitor 2B (p15 inhibits CDK4); Cyclin dependent kinase inhibitor 2B (p15, inhibits CDK4); cyclin-dependent kinase 4 inhibitor B; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); p14-INK4b; p15; p15-INK4b
Orthologs:
Homo sapiens (human) : CDKN2B (cyclin dependent kinase inhibitor 2B)  HGNC  Alliance
Mus musculus (house mouse) : Cdkn2b (cyclin dependent kinase inhibitor 2B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdkn2b (cyclin dependent kinase inhibitor 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : CDKN2B (cyclin dependent kinase inhibitor 2B)
Canis lupus familiaris (dog) : CDKN2B (cyclin dependent kinase inhibitor 2B)
Sus scrofa (pig) : CDKN2B (cyclin dependent kinase inhibitor 2B)
more info ...
Is Marker For: QTLs:   Tcas11  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05107,834,353 - 107,857,428 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05111,817,188 - 111,826,334 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45108,939,669 - 108,945,293 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15108,946,492 - 108,950,551 (-)NCBI
Celera5102,728,741 - 102,734,427 (-)NCBICelera
Cytogenetic Map5q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

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RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Cdkn2b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2324
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE



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