Gene: Psip1 (PC4 and SFRS1 interacting protein 1) Rattus norvegicus
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Symbol: Psip1
Name: PC4 and SFRS1 interacting protein 1
Description: ENCODES a protein that exhibits supercoiled DNA binding; activating transcription factor binding (ortholog); chromatin binding (ortholog); INVOLVED IN mRNA 5'-splice site recognition (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); response to heat (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); FOUND IN nuclear heterochromatin; transcriptionally active chromatin; nuclear periphery (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 17alpha-ethynylestradiol
AGR Description: Exhibits supercoiled DNA binding activity; predicted to be involved in several processes, including mRNA 5'-splice site recognition, positive regulation of transcription by RNA polymerase II, and response to heat; localizes to the nuclear heterochromatin and transcriptionally active chromatin; orthologous to human PSIP1 (PC4 and SFRS1 interacting protein 1).
Merged Description: Exhibits supercoiled DNA binding activity; predicted to be involved in several processes, including mRNA 5'-splice site recognition, positive regulation of transcription by RNA polymerase II, and response to heat; localizes to the nuclear heterochromatin and transcriptionally active chromatin; orthologous to human PSIP1 (PC4 and SFRS1 interacting protein 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ledgf; lens epithelium-derived growth factor; PC4 and SFRS1 interacting protein 2; PC4 and SFRS1-interacting protein; Psip2; SBP75; supercoiled DNA binding protein 75
Orthologs:
Homo sapiens (human) : PSIP1 (PC4 and SFRS1 interacting protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Psip1 (PC4 and SFRS1 interacting protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psip1 (PC4 and SFRS1 interacting protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100979736 (PC4 and SFRS1-interacting protein)
Canis lupus familiaris (dog) : PSIP1 (PC4 and SFRS1 interacting protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psip1 (PC4 and SFRS1 interacting protein 1)
Sus scrofa (pig) : PSIP1 (PC4 and SFRS1 interacting protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05101,555,691 - 101,588,659 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05105,568,304 - 105,601,260 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45102,304,948 - 102,336,608 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15102,310,173 - 102,341,834 (-)NCBI
Celera596,399,960 - 96,431,195 (-)NCBICelera
Cytogenetic Map5q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Psip1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631439
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.