Gene: Cebpa (CCAAT/enhancer binding protein alpha) Rattus norvegicus
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Symbol: Cebpa
Name: CCAAT/enhancer binding protein alpha
Description: ENCODES a protein that exhibits DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; histone deacetylase binding; INVOLVED IN acute-phase response; animal organ regeneration; cell differentiation; PARTICIPATES IN forkhead class A signaling pathway; acute myeloid leukemia pathway; ASSOCIATED WITH abnormal lipid level; ASSOCIATED WITH Acute-Phase Reaction; transient cerebral ischemia; acute myeloid leukemia (ortholog); FOUND IN CHOP-C/EBP complex; nuclear matrix; nucleolus; INTERACTS WITH (-)-cotinine; (S)-nicotine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane
AGR Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific, HMG box domain binding activity, and protein dimerization activity; involved in several processes, including acute-phase response, animal organ development, and regulation of cellular biosynthetic process; localizes to several cellular components, including the intracellular organelle; biomarker of transient cerebral ischemia; orthologous to human CEBPA (CCAAT enhancer binding protein alpha).
Merged Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific, HMG box domain binding activity, and protein dimerization activity; involved in several processes, including acute-phase response, animal organ development, and regulation of cellular biosynthetic process; localizes to several cellular components, including the intracellular organelle; biomarker of transient cerebral ischemia; orthologous to human CEBPA (CCAAT enhancer binding protein alpha); PARTICIPATES IN forkhead class A signaling pathway; acute myeloid leukemia pathway; INTERACTS WITH (-)-cotinine; (S)-nicotine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C/EBP alpha; CAAT/enhancer-binding protein DNA-binding protein; CAAT/enhancer-binding protein, DNA-binding protein; CCAAT/enhancer binding protein (C/EBP) alpha; CCAAT/enhancer binding protein (C/EBP), alpha; CCAAT/enhancer binding protein, alpha; CCAAT/enhancer-binding protein alpha; DBPCEP
Orthologs:
Homo sapiens (human) : CEBPA (CCAAT enhancer binding protein alpha)  HGNC  Alliance
Mus musculus (house mouse) : Cebpa (CCAAT/enhancer binding protein (C/EBP), alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cebpa (CCAAT enhancer binding protein alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : CEBPA (CCAAT enhancer binding protein alpha)
Canis lupus familiaris (dog) : CEBPA (CCAAT enhancer binding protein alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cebpa (CCAAT enhancer binding protein alpha)
Sus scrofa (pig) : CEBPA (CCAAT enhancer binding protein alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0191,363,492 - 91,366,164 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0192,493,857 - 92,495,245 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4187,626,111 - 87,627,499 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1187,704,351 - 87,705,428 (+)NCBI
Celera182,110,797 - 82,113,472 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Gene-Chemical Interaction Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Cebpa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2326
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.