Cebpa (CCAAT/enhancer binding protein alpha) - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Cebpa (CCAAT/enhancer binding protein alpha) Rattus norvegicus
Symbol: Cebpa
Name: CCAAT/enhancer binding protein alpha
RGD ID: 2326
Description: Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and protein dimerization activity. Contributes to sequence-specific DNA binding activity. Involved in several processes, including osteoblast development; regulation of transcription by RNA polymerase II; and response to vitamin B2. Located in nuclear matrix and nucleolus. Part of CHOP-C/EBP complex and Rb-E2F complex. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human CEBPA (CCAAT enhancer binding protein alpha); PARTICIPATES IN forkhead class A signaling pathway; acute myeloid leukemia pathway; INTERACTS WITH (+)-pilocarpine; (-)-cotinine; (S)-nicotine.
Type: protein-coding (Ensembl: lncRNA)
RefSeq Status: REVIEWED
Previously known as: C/EBP alpha; CAAT/enhancer-binding protein DNA-binding protein; CAAT/enhancer-binding protein, DNA-binding protein; CCAAT/enhancer binding protein (C/EBP) alpha; CCAAT/enhancer binding protein (C/EBP), alpha; CCAAT/enhancer binding protein, alpha; CCAAT/enhancer-binding protein alpha; DBPCEP
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2187,759,631 - 87,762,303 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl187,759,433 - 87,762,412 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx193,165,821 - 93,168,493 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01101,631,805 - 101,634,477 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0194,924,121 - 94,926,793 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0191,363,492 - 91,366,164 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl191,363,492 - 91,366,164 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0192,493,857 - 92,495,245 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4187,626,111 - 87,627,499 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1187,704,351 - 87,705,428 (+)NCBI
Celera182,110,797 - 82,113,472 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-artemisinic acid  (ISO)
(+)-pilocarpine  (EXP)
(-)-cotinine  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (EXP,ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,2-dimethylhydrazine  (ISO)
1-nitropyrene  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-acetamidofluorene  (EXP)
2-amino-2-deoxy-D-galactopyranose  (ISO)
2-amino-2-deoxy-D-glucopyranose 6-phosphate  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,5,6-trichloro-2-pyridinol  (ISO)
3,5,6-trichloropyridine-2-one  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyladenine  (ISO)
3-methylcholanthrene  (ISO)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-tert-Octylphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
9,10-epoxy-12-octadecenoic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
AICA ribonucleotide  (ISO)
alcohol  (ISO)
aldehydo-D-glucosamine 6-phosphate  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
andrographolide  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antimonite  (ISO)
antimycin A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
avobenzone  (ISO)
baicalein  (ISO)
benzamides  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzofurans  (ISO)
Benzyl parahydroxybenzoate  (ISO)
berberine  (ISO)
beta-carotene  (ISO)
beta-D-glucosamine 6-sulfate  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bismuth atom  (ISO)
bismuthane  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
boric acid  (ISO)
bortezomib  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
C60 fullerene  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
calcitriol  (ISO)
calcium dichloride  (ISO)
cannabidiolic acid  (ISO)
capsaicin  (EXP,ISO)
carbaryl  (ISO)
carbon nanotube  (ISO)
celastrol  (ISO)
celecoxib  (EXP)
cerulenin  (ISO)
ceruletide  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cholesterol  (ISO)
choline  (ISO)
cisplatin  (ISO)
clofazimine  (EXP)
Clofop  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (EXP,ISO)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
cortisol  (ISO)
cucurbitacin B  (ISO)
cucurbitacin I  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP)
deguelin  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dibutylstannane  (ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (EXP,ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diquat  (ISO)
doxorubicin  (ISO)
duvoglustat  (ISO)
efavirenz  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
endrin  (ISO)
enzalutamide  (ISO)
epoxiconazole  (ISO)
epoxomicin  (ISO)
ethanol  (EXP,ISO)
ethylparaben  (ISO)
etoposide  (ISO)
fenthion  (ISO)
fipronil  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (EXP,ISO)
gentamycin  (EXP)
Geraniin  (ISO)
gingerol  (ISO)
glucose  (ISO)
glycerol 2-phosphate  (ISO)
glycyrrhizinic acid  (ISO)
GW 501516  (ISO)
hemin  (ISO)
herbimycin  (EXP)
hesperetin  (ISO)
hexadecanoic acid  (EXP,ISO)
hispidulin  (ISO)
hydrazines  (ISO)
hydrogen peroxide  (ISO)
hydroxytyrosol  (ISO)
indirubin  (ISO)
indometacin  (ISO)
isoliquiritigenin  (ISO)
isoniazide  (ISO)
ivermectin  (ISO)
ketoconazole  (EXP)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (EXP)
LY294002  (ISO)
menadione  (ISO)
mercury dichloride  (ISO)
metformin  (EXP)
methimazole  (EXP)
methoxychlor  (EXP)
methylparaben  (ISO)
mifepristone  (ISO)
MK-2206  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nevirapine  (ISO)
nicotine  (EXP,ISO)
nicotinic acid  (ISO)
nimesulide  (EXP,ISO)
ochratoxin A  (ISO)
orlistat  (ISO)
osthole  (ISO)
p-tert-Amylphenol  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorobutanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
Phenylamil  (ISO)
phenylephrine  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
platycodin D  (ISO)
pomalidomide  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
propylparaben  (ISO)
prostaglandin E2  (ISO)
quercetin  (EXP,ISO)
raloxifene  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rimonabant  (ISO)
risperidone  (ISO)
ritonavir  (ISO)
rotenone  (EXP)
rottlerin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 203580  (ISO)
selenium atom  (ISO)
sildenafil citrate  (ISO)
silibinin  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sincalide  (EXP)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (ISO)
stavudine  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
Tanshinone I  (ISO)
taurine  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tolylfluanid  (ISO)
topiramate  (EXP)
tributylstannane  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (EXP,ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
valsartan  (ISO)
vinclozolin  (EXP)
vitamin D  (ISO)
vitamin E  (ISO)
zearalenone  (ISO)
zidovudine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute-phase response  (IEP)
animal organ regeneration  (IEP)
brown fat cell differentiation  (ISO)
cell differentiation  (IEP)
cell population proliferation  (ISO)
cellular response to lithium ion  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to tumor necrosis factor  (ISO)
cellular response to xenobiotic stimulus  (IEP)
cholesterol metabolic process  (ISO)
DNA-templated transcription  (IEA)
embryonic placenta development  (ISO)
epithelial cell maturation  (ISO)
fat cell differentiation  (IDA,ISO,ISS)
glucose homeostasis  (ISO,ISS)
granulocyte differentiation  (ISO,ISS)
hematopoietic stem cell proliferation  (ISO)
inner ear development  (ISO)
interleukin-6-mediated signaling pathway  (ISO)
lipid homeostasis  (ISO,ISS)
liver development  (IEP,ISO,ISS)
lung development  (ISO,ISS)
macrophage differentiation  (ISO)
memory  (IEP)
mitochondrion organization  (ISO)
myeloid cell differentiation  (IBA,ISO)
negative regulation of cell cycle  (ISO)
negative regulation of cell population proliferation  (IDA,ISO)
negative regulation of DNA-templated transcription  (IDA,ISO)
negative regulation of hematopoietic stem cell proliferation  (ISO)
negative regulation of transcription by RNA polymerase II  (IDA,ISO)
Notch signaling pathway  (ISO)
osteoblast development  (IEP)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of DNA-templated transcription initiation  (ISO)
positive regulation of fat cell differentiation  (IMP,ISO)
positive regulation of gene expression  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of macrophage activation  (ISO)
positive regulation of osteoblast differentiation  (ISO)
positive regulation of transcription by RNA polymerase II  (IDA,ISO)
regulation of cell population proliferation  (ISO)
regulation of DNA-templated transcription  (IDA,ISO,TAS)
regulation of transcription by RNA polymerase II  (IBA,ISO)
response to dexamethasone  (IEP)
response to nutrient  (IEP)
response to phenylpropanoid  (IEP)
response to vitamin B2  (IEP)
transcription by RNA polymerase I  (ISO,ISS)
urea cycle  (ISO)
white fat cell differentiation  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References - curated
# Reference Title Reference Citation
1. Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Blalock EM, etal., Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):2173-8. Epub 2004 Feb 9.
2. Transthyretin: A key gene involved in the maintenance of memory capacities during aging. Brouillette J and Quirion R, Neurobiol Aging. 2007 May 16.
3. Hepatic CCAAT/enhancer binding protein (C/EBP-alpha and C/EBP-beta) expression changes with riboflavin deficiency, diet restriction and starvation in rats. Chapin RB, etal., J Nutr. 1994 Dec;124(12):2365-75.
4. C/EBPalpha regulates osteoclast lineage commitment. Chen W, etal., Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7294-9. doi: 10.1073/pnas.1211383110. Epub 2013 Apr 11.
5. The dysfunction of hepatic transcriptional factors in mice with Huntington's Disease. Chiang MC, etal., Biochim Biophys Acta. 2011 Sep;1812(9):1111-20. Epub 2011 May 30.
6. Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease. Chiang MC, etal., Hum Mol Genet. 2007 Mar 1;16(5):483-98. Epub 2007 Jan 9.
7. C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism. Courselaud B, etal., J Biol Chem 2002 Oct 25;277(43):41163-70.
8. C/EBP alpha and C/EBP beta regulate haptoglobin gene expression during rat liver development and the acute-phase response. Dinic S, etal., Mol Biol Rep. 2005 Sep;32(3):141-7.
9. A PIT-1 homeodomain mutant blocks the intranuclear recruitment of the CCAAT/enhancer binding protein alpha required for prolactin gene transcription. Enwright JF 3rd, etal., Mol Endocrinol 2003 Feb;17(2):209-22.
10. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
11. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
12. Regulation of microglial proliferation during chronic neurodegeneration. Gomez-Nicola D, etal., J Neurosci. 2013 Feb 6;33(6):2481-93. doi: 10.1523/JNEUROSCI.4440-12.2013.
13. Functional interaction of bZIP proteins and the large subunit of replication factor C in liver and adipose cells. Hong S, etal., J Biol Chem. 2001 Jul 27;276(30):28098-105. Epub 2001 May 16.
14. Role of C/EBP proteins in hepatic and vascular smooth muscle transcription of human NHE1 gene. Kolyada AY, etal., Am J Physiol. 1995 Dec;269(6 Pt 1):C1408-16.
15. Isolation of a recombinant copy of the gene encoding C/EBP. Landschulz WH, etal., Genes Dev 1988 Jul;2(7):786-800.
16. A revised sequence of the rat c/ebp gene. Lincoln AJ, etal., Genes Dev 1994 May 1;8(9):1131-2.
17. Keratinocyte growth factor and the transcription factors C/EBP alpha, C/EBP delta, and SREBP-1c regulate fatty acid synthesis in alveolar type II cells. Mason RJ, etal., J Clin Invest 2003 Jul;112(2):244-55.
18. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
19. Structural basis for DNA recognition by the basic region leucine zipper transcription factor CCAAT/enhancer-binding protein alpha. Miller M, etal., J Biol Chem 2003 Apr 25;278(17):15178-84. Epub 2003 Feb 10.
20. Nucleolar retention of a translational C/EBPalpha isoform stimulates rDNA transcription and cell size. Muller C, etal., EMBO J. 2010 Mar 3;29(5):897-909. doi: 10.1038/emboj.2009.404. Epub 2010 Jan 14.
21. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
22. Portal blood flow regulates volume recovery of the rat liver after partial hepatectomy: molecular evaluation. Nobuoka T, etal., Eur Surg Res. 2006;38(6):522-32. Epub 2006 Oct 16.
23. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
24. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
25. CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials. Ossipow V, etal., Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):8219-23.
26. Cooperation between C/EBPalpha TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation. Pedersen TA, etal., Genes Dev. 2001 Dec 1;15(23):3208-16.
27. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
28. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
29. IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP. Poli V, etal., Cell 1990 Nov 2;63(3):643-53.
30. E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo. Porse BT, etal., Cell. 2001 Oct 19;107(2):247-58.
31. The CCAAT/enhancer binding protein (C/EBP) delta is differently regulated by fibrillar and oligomeric forms of the Alzheimer amyloid-beta peptide. Ramberg V, etal., J Neuroinflammation. 2011 Apr 14;8:34. doi: 10.1186/1742-2094-8-34.
32. HDAC3 interacts with sumoylated C/EBPalpha to negatively regulate the LXRalpha expression in rat hepatocytes. Ren J, etal., Mol Cell Endocrinol. 2013 Jul 15;374(1-2):35-45. doi: 10.1016/j.mce.2013.04.013. Epub 2013 Apr 29.
33. GOA pipeline RGD automated data pipeline
34. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
35. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
36. Members of the C/EBP transcription factor family stimulate expression of the human and rat surfactant protein A (SP-A) genes. Rosenberg E, etal., Biochim Biophys Acta 2002 May 3;1575(1-3):82-90.
37. Age-dependent response of CCAAT/enhancer binding proteins following traumatic brain injury in mice. Sandhir R and Berman NE, Neurochem Int. 2010 Jan;56(1):188-93. doi: 10.1016/j.neuint.2009.10.002. Epub 2009 Oct 13.
38. Sumoylation of CCAAT/enhancer-binding protein alpha and its functional roles in hepatocyte differentiation. Sato Y, etal., J Biol Chem. 2006 Aug 4;281(31):21629-39. Epub 2006 May 30.
39. Dexamethasone reverses TGF-beta-mediated inhibition of primary rat preadipocyte differentiation. Shin SM, etal., FEBS Lett. 2003 May 22;543(1-3):25-30.
40. Localization of 54 rat genes, and definition of new synteny groups conserved in the human and the rat. Szpirer C, etal., Mamm Genome 2000 Sep;11(9):729-35
41. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
42. Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gamma. Thomassin H, etal., Nucleic Acids Res 1992 Jun 25;20(12):3091-8.
43. Downregulation of cytochromes P450 in growth-stimulated rat hepatocytes: role of c-Myc induction and impaired C/EBP binding to DNA. Tinel M, etal., J Hepatol. 2003 Aug;39(2):171-8.
44. Lamin A/C deficiency is associated with fat infiltration of muscle and bone. Tong J, etal., Mech Ageing Dev. 2011 Nov-Dec;132(11-12):552-9. doi: 10.1016/j.mad.2011.09.004. Epub 2011 Oct 1.
45. Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element. Ubeda M, etal., Mol Cell Biol. 1996 Apr;16(4):1479-89.
46. CCAAT-enhancer binding protein alpha is expressed in activated microglial cells after brain injury. Walton M, etal., Brain Res Mol Brain Res. 1998 Oct 30;61(1-2):11-22.
47. The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. Wissmuller S, etal., Nucleic Acids Res. 2006 Mar 31;34(6):1735-44. Print 2006.
48. Epimedium-derived flavonoids modulate the balance between osteogenic differentiation and adipogenic differentiation in bone marrow stromal cells of ovariectomized rats via Wnt/beta-catenin signal pathway activation. Xu YX, etal., Chin J Integr Med. 2012 Dec;18(12):909-17. doi: 10.1007/s11655-012-1294-2. Epub 2012 Dec 13.
49. Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes. Zaragoza K, etal., Mol Cell Biol. 2010 May;30(9):2293-304. doi: 10.1128/MCB.01619-09. Epub 2010 Feb 22.
Additional References at PubMed
PMID:1618860   PMID:1935900   PMID:7959007   PMID:8798745   PMID:9372966   PMID:9545285   PMID:10075730   PMID:10233885   PMID:10510303   PMID:10859308   PMID:10921906   PMID:10937998  
PMID:11242107   PMID:11940593   PMID:12006103   PMID:12037571   PMID:12055200   PMID:12502791   PMID:12695546   PMID:12821655   PMID:12861022   PMID:12896875   PMID:14660596   PMID:15073037  
PMID:15107404   PMID:15130516   PMID:15175325   PMID:15504357   PMID:15509779   PMID:15519652   PMID:15589173   PMID:15632071   PMID:15664994   PMID:15673614   PMID:16407263   PMID:16445384  
PMID:16467360   PMID:16600022   PMID:16774685   PMID:16893891   PMID:16912278   PMID:16946298   PMID:17021047   PMID:17090532   PMID:17097562   PMID:17290224   PMID:17966466   PMID:18026136  
PMID:18328085   PMID:18492766   PMID:18632661   PMID:18824566   PMID:18949049   PMID:18974039   PMID:19168033   PMID:19932685   PMID:20219337   PMID:20972335   PMID:21131957   PMID:21227534  
PMID:21249617   PMID:21454593   PMID:21539866   PMID:21669876   PMID:21795542   PMID:21996045   PMID:22780989   PMID:22985399   PMID:23392382   PMID:23508841   PMID:23881867   PMID:23937658  
PMID:23993269   PMID:24429361   PMID:24913911   PMID:25446530   PMID:27746211   PMID:28186500   PMID:28902364   PMID:32363643   PMID:32814091   PMID:34217716   PMID:35883192   PMID:36132983  


Comparative Map Data
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2187,759,631 - 87,762,303 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl187,759,433 - 87,762,412 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx193,165,821 - 93,168,493 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01101,631,805 - 101,634,477 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0194,924,121 - 94,926,793 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0191,363,492 - 91,366,164 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl191,363,492 - 91,366,164 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0192,493,857 - 92,495,245 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4187,626,111 - 87,627,499 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1187,704,351 - 87,705,428 (+)NCBI
Celera182,110,797 - 82,113,472 (+)NCBICelera
Cytogenetic Map1q21NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381933,299,934 - 33,302,534 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1933,299,934 - 33,302,534 (-)EnsemblGRCh38hg38GRCh38
GRCh371933,790,840 - 33,793,440 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361938,482,776 - 38,485,160 (-)NCBINCBI36Build 36hg18NCBI36
Build 341938,482,775 - 38,485,160NCBI
Celera1930,484,405 - 30,486,995 (-)NCBICelera
Cytogenetic Map19q13.11NCBI
HuRef1930,291,676 - 30,294,205 (-)NCBIHuRef
CHM1_11933,791,795 - 33,794,385 (-)NCBICHM1_1
T2T-CHM13v2.01935,819,706 - 35,822,306 (-)NCBIT2T-CHM13v2.0
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39734,818,718 - 34,821,353 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl734,818,718 - 34,821,353 (+)EnsemblGRCm39 Ensembl
GRCm38735,119,293 - 35,121,928 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl735,119,293 - 35,121,928 (+)EnsemblGRCm38mm10GRCm38
MGSCv37735,904,312 - 35,906,947 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36734,828,063 - 34,830,688 (+)NCBIMGSCv36mm8
Celera730,255,122 - 30,257,756 (+)NCBICelera
Cytogenetic Map7B2NCBI
cM Map721.02NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_0049554683,047,931 - 3,049,080 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554683,046,544 - 3,049,217 (-)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
NHGRI_mPanPan11941,273,099 - 41,275,733 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01930,223,567 - 30,226,204 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11938,969,065 - 38,971,031 (-)NCBIpanpan1.1PanPan1.1panPan2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.11118,846,252 - 118,851,045 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1118,249,214 - 118,251,848 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01119,446,691 - 119,449,313 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11119,007,283 - 119,009,910 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01118,633,880 - 118,636,501 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01119,692,609 - 119,695,231 (+)NCBIUU_Cfam_GSD_1.0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_0244093499,129,664 - 9,132,348 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365702,513,561 - 2,516,213 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl643,083,207 - 43,085,836 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1643,083,200 - 43,085,884 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2638,632,195 - 38,634,910 (-)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1628,342,506 - 28,345,759 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl628,343,907 - 28,344,977 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660736,065,215 - 6,067,832 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla 1.0NW_0046247949,809,007 - 9,813,418 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Variants in Cebpa
11 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:51
Count of miRNA genes:44
Interacting mature miRNAs:50
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat

Markers in Region
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,758,629 - 87,758,781 (+)MAPPERmRatBN7.2
Rnor_6.0191,362,491 - 91,362,642NCBIRnor6.0
Rnor_5.0192,492,865 - 92,493,016UniSTSRnor5.0
RGSC_v3.4187,625,118 - 87,625,270RGDRGSC3.4
RGSC_v3.4187,625,119 - 87,625,270UniSTSRGSC3.4
RGSC_v3.1187,703,229 - 87,703,381RGD
Celera182,109,796 - 82,109,947UniSTS
RH 3.4 Map1842.1UniSTS
RH 3.4 Map1842.1RGD
SHRSP x BN Map143.4499UniSTS
SHRSP x BN Map143.4499RGD
Cytogenetic Map1q22UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,758,555 - 87,758,780 (+)MAPPERmRatBN7.2
Rnor_6.0191,362,417 - 91,362,641NCBIRnor6.0
Rnor_5.0192,492,791 - 92,493,015UniSTSRnor5.0
RGSC_v3.4187,625,045 - 87,625,269UniSTSRGSC3.4
Celera182,109,722 - 82,109,946UniSTS
Cytogenetic Map1q22UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,759,761 - 87,760,401 (+)MAPPERmRatBN7.2
Rnor_6.0191,363,623 - 91,364,262NCBIRnor6.0
Rnor_5.0192,493,997 - 92,494,636UniSTSRnor5.0
RGSC_v3.4187,626,251 - 87,626,890UniSTSRGSC3.4
Celera182,110,928 - 82,111,567UniSTS
Cytogenetic Map1q22UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,760,686 - 87,760,768 (+)MAPPERmRatBN7.2
Rnor_6.0191,364,548 - 91,364,629NCBIRnor6.0
Rnor_5.0192,494,922 - 92,495,003UniSTSRnor5.0
RGSC_v3.4187,627,176 - 87,627,257UniSTSRGSC3.4
Celera182,111,853 - 82,111,934UniSTS
Cytogenetic Map1q22UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,760,573 - 87,760,672 (+)MAPPERmRatBN7.2
Rnor_6.0191,364,435 - 91,364,533NCBIRnor6.0
Rnor_5.0192,494,809 - 92,494,907UniSTSRnor5.0
RGSC_v3.4187,627,063 - 87,627,161UniSTSRGSC3.4
Celera182,111,740 - 82,111,838UniSTS
Cytogenetic Map1q22UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,760,567 - 87,760,756 (+)MAPPERmRatBN7.2
Rnor_6.0191,364,429 - 91,364,617NCBIRnor6.0
Rnor_5.0192,494,803 - 92,494,991UniSTSRnor5.0
RGSC_v3.4187,627,057 - 87,627,245UniSTSRGSC3.4
Celera182,111,734 - 82,111,922UniSTS
Cytogenetic Map1q22UniSTS


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
Medium 3 53 41 11 41 21 13 11
Low 37 4 8 8 11 74 14 27 8
Below cutoff 6 1


RefSeq Acc Id: ENSRNOT00000014517   ⟹   ENSRNOP00000063123
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl187,759,433 - 87,762,412 (-)Ensembl
Rnor_6.0 Ensembl191,363,492 - 91,366,164 (+)Ensembl
RefSeq Acc Id: NM_001287577   ⟹   NP_001274506
RefSeq Status: REVIEWED
Rat AssemblyChrPosition (strand)Source
mRatBN7.2187,759,631 - 87,762,303 (+)NCBI
Rnor_6.0191,363,492 - 91,366,164 (+)NCBI
Celera182,110,797 - 82,113,472 (+)NCBI
RefSeq Acc Id: NM_001287578   ⟹   NP_001274507
RefSeq Status: REVIEWED
Rat AssemblyChrPosition (strand)Source
mRatBN7.2187,759,631 - 87,762,303 (+)NCBI
Rnor_6.0191,363,492 - 91,366,164 (+)NCBI
Celera182,110,797 - 82,113,472 (+)NCBI
RefSeq Acc Id: NM_001287579   ⟹   NP_001274508
RefSeq Status: REVIEWED
Rat AssemblyChrPosition (strand)Source
mRatBN7.2187,759,631 - 87,762,303 (+)NCBI
Rnor_6.0191,363,492 - 91,366,164 (+)NCBI
Celera182,110,797 - 82,113,472 (+)NCBI
RefSeq Acc Id: NM_012524   ⟹   NP_036656
RefSeq Status: REVIEWED
Rat AssemblyChrPosition (strand)Source
mRatBN7.2187,759,631 - 87,762,303 (+)NCBI
Rnor_6.0191,363,492 - 91,366,164 (+)NCBI
Rnor_5.0192,493,857 - 92,495,245 (+)NCBI
RGSC_v3.4187,626,111 - 87,627,499 (+)RGD
Celera182,110,797 - 82,113,472 (+)NCBI
RefSeq Acc Id: NP_036656   ⟸   NM_012524
- Peptide Label: isoform a
- UniProtKB: P05554 (UniProtKB/Swiss-Prot),   A6JAA1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001274506   ⟸   NM_001287577
- Peptide Label: isoform c
- UniProtKB: P05554 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001274507   ⟸   NM_001287578
- Peptide Label: isoform d
- UniProtKB: P05554 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001274508   ⟸   NM_001287579
- Peptide Label: isoform b
- UniProtKB: P05554 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063123   ⟸   ENSRNOT00000014517
Protein Domains

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05554-F1-model_v2 AlphaFold P05554 1-358 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2326 AgrOrtholog
BioCyc Gene G2FUF-59987 BioCyc
Ensembl Genes ENSRNOG00000010918 Ensembl
Gene3D-CATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C/EBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C/EBP_chordates UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24252 UniProtKB/Swiss-Prot
Pfam bZIP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cebpa PhenoGen
PIRSF CCAAT/enhancer-binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BRLZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Leucine zipper domain UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
TIGR TC206743

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Cebpa  CCAAT/enhancer binding protein alpha  Cebpa  CCAAT/enhancer binding protein (C/EBP), alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Cebpa  CCAAT/enhancer binding protein (C/EBP), alpha    CCAAT/enhancer binding protein, alpha  Name updated 1299863 APPROVED
2002-11-06 Cebpa  CCAAT/enhancer binding protein, alpha    CCAAT/enhancer binding protein (C/EBP), alpha  Name updated 625702 APPROVED
2002-02-20 Cebpa  CCAAT/enhancer binding protein (C/EBP), alpha      Name updated to reflect Human and Mouse nomenclature 70282 APPROVED