(+)-artemisinin decreases activity ISO RGD:737416 6480464 artemisinin results in decreased activity of CYP2C19 protein CTD PMID:11124226 (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2C6V1 mRNA] CTD PMID:31150632 (3-phenoxyphenyl)methanol increases abundance ISO RGD:737416 6480464 CYP2C19 protein results in increased abundance of 3-phenoxybenzylalcohol CTD PMID:24548679 (E)-thiamethoxam decreases expression ISO RGD:737416 6480464 Thiamethoxam results in decreased expression of CYP2C19 protein CTD PMID:32194361 (E,E)-germacrone decreases activity ISO RGD:737416 6480464 germacrone results in decreased activity of CYP2C19 protein CTD PMID:23850985 (R)-lipoic acid multiple interactions ISO RGD:737416 6480464 Thioctic Acid inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 (S)-naringenin decreases activity ISO RGD:737416 6480464 naringenin results in decreased activity of CYP2C19 protein CTD PMID:29753067 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane increases chemical synthesis ISO RGD:737416 6480464 CYP2C19 protein results in increased chemical synthesis of 1 more ... CTD PMID:9714305 , PMID:9733665 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of 1 more ... CTD PMID:9714305 1,2-dichloroethane increases expression ISO RGD:1624096 6480464 ethylene dichloride results in increased expression of CYP2C38 mRNA CTD PMID:28189721 , PMID:28960355 1,2-dichloroethene decreases activity EXP 6480464 1, 2-dichloroethylene results in decreased activity of CYP2C6V1 protein CTD PMID:9671540 1,4-naphthoquinone increases abundance ISO RGD:737416 6480464 CYP2C19 protein results in increased abundance of 1, 4-naphthoquinone CTD PMID:16243959 1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol decreases activity ISO RGD:737416 6480464 stiripentol results in decreased activity of CYP2C19 protein CTD PMID:16022579 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile decreases methylation ISO RGD:737416 6480464 CYP2C19 protein polymorphism results in decreased methylation of Citalopram, CYP2C19 protein results in decreased methylation of Citalopram analog CTD PMID:12975335 , PMID:9110356 1-naphthol increases abundance ISO RGD:737416 6480464 CYP2C19 protein results in increased abundance of 1-naphthol CTD PMID:16243959 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of CYP2C6V1 mRNA CTD PMID:15953391 more ... 17alpha-ethynylestradiol increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Ethinyl Estradiol CTD PMID:15304426 17alpha-ethynylestradiol multiple interactions ISO RGD:737416 6480464 [Ethinyl Estradiol co-treated with norgestimate] results in decreased activity of CYP2C19 protein CTD PMID:16291717 17beta-estradiol increases chemical synthesis ISO RGD:737416 6480464 CYP2C19 protein results in increased chemical synthesis of Estradiol CTD PMID:9714305 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of CYP2C6V1 mRNA CTD PMID:32145629 1H-pyrazole decreases expression ISO RGD:1624096 6480464 pyrazole results in decreased expression of CYP2C38 mRNA CTD PMID:17945193 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1624096 6480464 [2 more ... CTD PMID:25510870 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:31826744 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:1624096 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2C6V1 mRNA CTD PMID:21724226 , PMID:32387183 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1624096 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2C38 mRNA CTD PMID:19770486 , PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:737416 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2C19 mRNA CTD PMID:16985168 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:737416 6480464 Tetrachlorodibenzodioxin affects the expression of CYP2C19 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:737416 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP2C19 mRNA CTD PMID:20106945 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases oxidation EXP 6480464 CYP2C6V1 protein results in increased oxidation of 2 more ... CTD PMID:21673328 2,4-dibromophenyl 2,4,5-tribromophenyl ether multiple interactions EXP 6480464 [CYP2C6V1 protein results in increased oxidation of 2 more ... CTD PMID:21673328 2,6-di-tert-butyl-4-methylphenol increases expression EXP 6480464 Butylated Hydroxytoluene results in increased expression of CYP2C6V1 mRNA CTD PMID:18539377 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Praziquantel CTD PMID:12920490 2-nitroanisole increases oxidation EXP 6480464 CYP2C6V1 protein results in increased oxidation of 2-nitroanisole CTD PMID:21218109 2-nitroanisole increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of 2-nitroanisole CTD PMID:21218109 2-tert-butylhydroquinone increases expression ISO RGD:737416 6480464 2-tert-butylhydroquinone results in increased expression of CYP2C19 mRNA, 2-tert-butylhydroquinone results in increased expression of CYP2C19 protein CTD PMID:24830941 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:737416 6480464 3 more ... CTD PMID:19692669 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 AHR gene mutant form inhibits the reaction [3 more ... CTD PMID:34256052 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:34256052 3,5,6-trichloro-2-pyridinol increases chemical synthesis ISO RGD:737416 6480464 CYP2C19 protein results in increased chemical synthesis of 3 more ... CTD PMID:22281205 3,5,6-trichloropyridine-2-one increases chemical synthesis ISO RGD:737416 6480464 CYP2C19 protein results in increased chemical synthesis of 3 more ... CTD PMID:22281205 3,5-xylenol multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased oxidation of 3, 5-xylenol analog] which results in increased abundance of 4-(methylsulfinyl)phenol analog CTD PMID:27665777 3,5-xylenol increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of 3, 5-xylenol analog CTD PMID:27665777 4-(methylsulfinyl)phenol multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased oxidation of 3, 5-xylenol analog] which results in increased abundance of 4-(methylsulfinyl)phenol analog CTD PMID:27665777 4-(methylsulfinyl)phenol increases abundance ISO RGD:737416 6480464 CYP2C19 protein results in increased abundance of 4-(methylsulfinyl)phenol analog CTD PMID:27665777 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:11774366 4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of 1-(4-hydroxyphenyl)-1, 2-diphenyl-1-butene CTD PMID:29285606 4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of 1-(4-hydroxyphenyl)-1 more ... CTD PMID:29285606 4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol increases abundance ISO RGD:737416 6480464 CYP2C19 protein results in increased abundance of 1-(4-hydroxyphenyl)-1, 2-diphenyl-1-butene CTD PMID:29285606 4-bromo-2-chlorophenol multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of profenofos] which results in increased abundance of 4-bromo-2-chlorophenol CTD PMID:23415833 4-hydroxychalcone affects chemical synthesis EXP 6480464 CYP2C6V1 protein affects the chemical synthesis of 4-hydroxychalcone CTD PMID:15863696 4-hydroxycyclophosphamide multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide CTD PMID:30500380 4-hydroxytolbutamide multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased hydroxylation of Tolbutamide] which results in increased chemical synthesis of 4'-hydroxytolbutamide CTD PMID:30500380 4-Ipomeanol increases activity ISO RGD:737416 6480464 CYP2C19 protein results in increased activity of 4-ipomeanol CTD PMID:15892579 4-nitrophenol increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of 4-nitrophenol CTD PMID:15135088 4-tert-Octylphenol increases response to substance ISO RGD:737416 6480464 CYP2C19 gene SNP results in increased susceptibility to 4-tert-octylphenol CTD PMID:23555028 5-hydroxydiclofenac multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac CTD PMID:24246759 5-Hydroxythalidomide increases abundance ISO RGD:737416 6480464 CYP2C19 protein results in increased abundance of 5'-hydroxythalidomide, CYP2C19 protein results in increased abundance of 5-hydroxythalidomide CTD PMID:24350712 5-Hydroxythalidomide multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5'-hydroxythalidomide more ... CTD PMID:20443640 , PMID:24350712 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions ISO RGD:737416 6480464 [5-bromotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole more ... CTD PMID:11752104 more ... 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole decreases metabolic processing ISO RGD:737416 6480464 CYP2C19 gene alternative form results in decreased metabolism of Omeprazole CTD PMID:20573087 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Omeprazole CTD PMID:14586384 more ... 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Omeprazole CTD PMID:12637241 more ... 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Omeprazole CTD PMID:11752104 more ... 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole decreases activity ISO RGD:737416 6480464 Omeprazole results in decreased activity of CYP2C19 protein CTD PMID:15306208 more ... 5-methoxy-N,N-diisopropyltryptamine multiple interactions ISO RGD:737416 6480464 [5-methoxy-N, N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole CTD PMID:26599973 5-methoxy-N,N-diisopropyltryptamine decreases activity ISO RGD:737416 6480464 5-methoxy-N, N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein CTD PMID:26599973 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of CYP2C6V1 mRNA CTD PMID:30047161 7,12-dimethyltetraphene multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of and results in increased activity of 9 more ... CTD PMID:32159784 7-hydroxyflavone decreases activity ISO RGD:737416 6480464 7-hydroxyflavone results in decreased activity of CYP2C19 protein CTD PMID:29753067 acenocoumarol affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Acenocoumarol CTD PMID:11918509 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of CYP2C6V1 mRNA CTD PMID:31881176 aconitine multiple interactions ISO RGD:737416 6480464 [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of Aconitine metabolite CTD PMID:21277363 acrolein multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of Acrolein CTD PMID:30500380 adinazolam decreases methylation ISO RGD:737416 6480464 CYP2C19 protein results in decreased methylation of adinazolam CTD PMID:9600717 adinazolam multiple interactions ISO RGD:737416 6480464 Omeprazole inhibits the reaction [CYP2C19 protein results in decreased methylation of adinazolam] CTD PMID:9600717 ADP multiple interactions ISO RGD:737416 6480464 CYP2C19 gene affects the susceptibility to [Adenosine Diphosphate co-treated with clopidogrel] more ... CTD PMID:16772608 more ... afimoxifene increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of afimoxifene CTD PMID:29285606 aflatoxin B1 affects expression ISO RGD:737416 6480464 Aflatoxin B1 affects the expression of CYP2C19 protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO RGD:737416 6480464 Aflatoxin B1 results in decreased methylation of CYP2C19 gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO RGD:737416 6480464 Aflatoxin B1 results in decreased expression of CYP2C19 mRNA CTD PMID:22100608 , PMID:27153756 aflatoxin B1 multiple interactions ISO RGD:737416 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Aflatoxin B1 CTD PMID:23397584 all-trans-retinoic acid multiple interactions EXP 6480464 AHR protein promotes the reaction [CYP2C6V1 protein results in increased hydroxylation of Tretinoin] CTD PMID:14623888 all-trans-retinoic acid decreases expression ISO RGD:737416 6480464 Tretinoin results in decreased expression of CYP2C19 mRNA CTD PMID:16985168 all-trans-retinoic acid increases hydroxylation EXP 6480464 CYP2C6V1 protein results in increased hydroxylation of Tretinoin CTD PMID:14623888 almotriptan decreases methylation ISO RGD:737416 6480464 CYP2C19 protein results in decreased methylation of almotriptan CTD PMID:12642466 Aloe emodin decreases activity ISO RGD:737416 6480464 aloe emodin results in decreased activity of CYP2C19 protein CTD PMID:33438235 alpha-hexachlorocyclohexane increases expression EXP 6480464 alpha-hexachlorocyclohexane results in increased expression of CYP2C6V1 mRNA CTD PMID:16940010 alpha-hexachlorocyclohexane multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C6V1 protein CTD PMID:16246485 alpha-linolenic acid multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of [alpha-Linolenic Acid co-treated with NADP] CTD PMID:16978661 alpha-linolenic acid decreases activity ISO RGD:737416 6480464 alpha-Linolenic Acid results in decreased activity of CYP2C19 protein CTD PMID:16978661 alpha-methyltryptamine decreases activity ISO RGD:737416 6480464 indopan results in decreased activity of CYP2C19 protein CTD PMID:26599973 alpha-methyltryptamine multiple interactions ISO RGD:737416 6480464 [indopan results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole CTD PMID:26599973 amiodarone decreases response to substance ISO RGD:737416 6480464 CYP2C19 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 amitriptyline increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Amitriptyline CTD PMID:27320963 amitriptyline multiple interactions ISO RGD:737416 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Amitriptyline CTD PMID:23397584 amitriptylinoxide increases abundance ISO RGD:737416 6480464 CYP2C19 protein results in increased abundance of amitriptyline N-oxide CTD PMID:27320963 amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of CYP2C6V1 mRNA CTD PMID:30047161 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CYP2C6V1 mRNA CTD PMID:16483693 amodiaquine decreases activity ISO RGD:737416 6480464 Amodiaquine results in decreased activity of CYP2C19 protein CTD PMID:11124226 amodiaquine increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Amodiaquine CTD PMID:31629065 amodiaquine multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine CTD PMID:31629065 amphetamine decreases methylation ISO RGD:737416 6480464 CYP2C19 protein results in decreased methylation of Amphetamine analog CTD PMID:29277574 amphetamine increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of Amphetamine analog CTD PMID:29277574 amphetamine increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Amphetamine analog CTD PMID:29277574 amphotericin B increases expression ISO RGD:737416 6480464 Amphotericin B analog results in increased expression of CYP2C19 mRNA CTD PMID:28534445 arachidonic acid decreases activity ISO RGD:737416 6480464 Arachidonic Acid results in decreased activity of CYP2C19 protein CTD PMID:16978661 arachidonic acid increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Arachidonic Acid CTD PMID:12675279 arachidonic acid multiple interactions ISO RGD:737416 6480464 CYP2C19 gene SNP affects the susceptibility to [Adenosine Diphosphate co-treated with Arachidonic Acid], CYP2C19 protein results in increased metabolism of [Arachidonic Acid co-treated with NADP] CTD PMID:16978661 , PMID:18004210 aristolochic acid A multiple interactions EXP 6480464 [CYP2C6V1 protein co-treated with CYB5A protein] results in increased abundance of aristolochic acid I metabolite, [CYP2C6V1 protein co-treated with CYB5A protein] results in increased metabolism of aristolochic acid I CTD PMID:21362632 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of CYP2C6V1 protein CTD PMID:8471063 Aroclor 1254 decreases expression ISO RGD:1624096 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2C38 mRNA CTD PMID:25270620 Aroclor 1254 increases expression ISO RGD:737416 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of CYP2C19 mRNA CTD PMID:17851650 Asiaticoside decreases activity ISO RGD:737416 6480464 asiaticoside results in decreased activity of CYP2C19 protein CTD PMID:21349323 atazanavir sulfate multiple interactions ISO RGD:737416 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP2C19 mRNA CTD PMID:33819548 atrazine multiple interactions ISO RGD:737416 6480464 [CYP1A1 protein co-treated with CYP2B6 protein co-treated with CYP2C19 protein] results in decreased susceptibility to [norflurazone co-treated with metolachlor co-treated with Atrazine], [CYP1A1 protein co-treated with CYP2B6 protein co-treated with CYP2C19 protein] results in decreased susceptibility to Atrazine CTD PMID:16608219 Auriculasin multiple interactions ISO RGD:737416 6480464 Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of auriculasin] CTD PMID:31515991 Auriculasin increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of auriculasin CTD PMID:31515991 Avasimibe decreases activity ISO RGD:737416 6480464 avasimibe results in decreased activity of CYP2C19 protein CTD PMID:15333513 azoxystrobin decreases expression ISO RGD:737416 6480464 azoxystrobin results in decreased expression of CYP2C19 protein CTD PMID:32194361 baicalein decreases activity ISO RGD:737416 6480464 baicalein results in decreased activity of CYP2C19 protein CTD PMID:29753067 barnidipine decreases activity ISO RGD:737416 6480464 mepirodipine results in decreased activity of CYP2C19 protein CTD PMID:10805063 benfuracarb increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of benfuracarb CTD PMID:24016712 benidipine decreases activity ISO RGD:737416 6480464 benidipine results in decreased activity of CYP2C19 protein CTD PMID:10805063 benzbromarone multiple interactions ISO RGD:737416 6480464 Benzbromarone analog binds to and results in decreased activity of CYP2C19 protein, Benzbromarone binds to and results in decreased activity of CYP2C19 protein CTD PMID:15615526 benzo[a]pyrene multiple interactions ISO RGD:737416 6480464 [Benzo(a)pyrene co-treated with dibenzo(a, l)pyrene] results in increased expression of CYP2C19 mRNA CTD PMID:17690111 benzo[a]pyrene decreases expression ISO RGD:737416 6480464 Benzo(a)pyrene results in decreased expression of CYP2C19 mRNA CTD PMID:32234424 benzo[a]pyrene increases expression ISO RGD:1624096 6480464 Benzo(a)pyrene results in increased expression of CYP2C38 mRNA CTD PMID:21964900 , PMID:23735875 benzylideneacetone increases oxidation EXP 6480464 CYP2C6V1 protein results in increased oxidation of benzylideneacetone CTD PMID:15863696 beta-hexachlorocyclohexane decreases expression ISO RGD:1624096 6480464 beta-hexachlorocyclohexane results in decreased expression of CYP2C38 mRNA CTD PMID:25270620 beta-naphthoflavone decreases expression ISO RGD:737416 6480464 beta-Naphthoflavone results in decreased expression of CYP2C19 mRNA CTD PMID:16985168 , PMID:33263786 beta-naphthoflavone multiple interactions EXP 6480464 [Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of CYP2C6V1 protein CTD PMID:30842367 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:1624096 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of CYP2C38 mRNA] CTD PMID:19850644 bis(2-ethylhexyl) phthalate increases expression ISO RGD:1624096 6480464 Diethylhexyl Phthalate results in increased expression of CYP2C38 mRNA CTD PMID:19850644 bisphenol A increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of bisphenol A, CYP2C19 protein results in increased hydroxylation of bisphenol A metabolite CTD PMID:23470418 bisphenol A decreases methylation ISO RGD:737416 6480464 bisphenol A results in decreased methylation of CYP2C19 gene CTD PMID:31601247 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CYP2C6V1 mRNA CTD PMID:30903817 , PMID:32145629 bisphenol A decreases activity ISO RGD:737416 6480464 bisphenol A results in decreased activity of CYP2C19 protein CTD PMID:10784435 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CYP2C19 mRNA CTD PMID:25181051 bisphenol A increases glutathionylation ISO RGD:737416 6480464 CYP2C19 protein results in increased glutathionylation of bisphenol A, CYP2C19 protein results in increased glutathionylation of bisphenol A metabolite CTD PMID:23470418 bisphenol F increases glutathionylation ISO RGD:737416 6480464 CYP2C19 protein results in increased glutathionylation of 4 more ... CTD PMID:23470418 bisphenol F increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of 4, 4'-bisphenol F CTD PMID:23470418 bortezomib affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Bortezomib CTD PMID:15764713 bromfenac increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of bromfenac CTD PMID:31815452 Bufuralol increases hydroxylation EXP 6480464 CYP2C6V1 protein results in increased hydroxylation of bufuralol CTD PMID:11911841 Bufuralol increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of bufuralol CTD PMID:9429232 bupropion multiple interactions ISO RGD:737416 6480464 CYP2C19 gene polymorphism affects the metabolism of and affects the abundance of Bupropion CTD PMID:25187485 cadmium dichloride multiple interactions ISO RGD:1624096 6480464 MT3 affects the reaction [Cadmium Chloride affects the expression of CYP2C38 mRNA] CTD PMID:20371981 calcitriol increases expression ISO RGD:737416 6480464 Calcitriol results in increased expression of CYP2C19 mRNA CTD PMID:27107558 cannabidiol decreases activity ISO RGD:737416 6480464 Cannabidiol results in decreased activity of CYP2C19 protein CTD PMID:24667653 capsaicin decreases activity ISO RGD:737416 6480464 Capsaicin results in decreased activity of CYP2C19 protein CTD PMID:22375877 captan increases expression ISO RGD:1624096 6480464 Captan results in increased expression of CYP2C38 mRNA CTD PMID:31558096 captan decreases expression ISO RGD:737416 6480464 Captan results in decreased expression of CYP2C19 protein CTD PMID:32194361 carbamazepine increases expression ISO RGD:737416 6480464 Carbamazepine results in increased expression of CYP2C19 mRNA CTD PMID:17112801 carbamazepine multiple interactions ISO RGD:737416 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Carbamazepine CTD PMID:23397584 carbendazim decreases expression ISO RGD:737416 6480464 carbendazim results in decreased expression of CYP2C19 protein CTD PMID:32194361 carbofuran increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Carbofuran CTD PMID:15560889 carisoprodol multiple interactions ISO RGD:737416 6480464 [CYP2C19 gene polymorphism affects the metabolism of Carisoprodol] which affects the chemical synthesis of Meprobamate, [CYP2C19 protein results in increased metabolism of Carisoprodol] which results in increased chemical synthesis of Meprobamate CTD PMID:12835613 , PMID:22527345 Carnosol decreases activity ISO RGD:737416 6480464 carnosol results in decreased activity of CYP2C19 protein CTD PMID:34592323 CGP 52608 multiple interactions ISO RGD:737416 6480464 CGP 52608 promotes the reaction [RORA protein binds to CYP2C19 gene] CTD PMID:28238834 chalcone increases hydroxylation EXP 6480464 CYP2C6V1 protein results in increased hydroxylation of Chalcone CTD PMID:15863696 chelidonine increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of chelidonine CTD PMID:31102647 chelidonine multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of chelidonine] which results in increased abundance of Glutathione analog CTD PMID:31102647 chenodeoxycholic acid multiple interactions ISO RGD:737416 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C19 mRNA more ... CTD PMID:33819548 chloramphenicol decreases activity ISO RGD:737416 6480464 Chloramphenicol results in decreased activity of CYP2C19 protein CTD PMID:26599973 chloramphenicol multiple interactions ISO RGD:737416 6480464 [Chloramphenicol results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole CTD PMID:26599973 chlorohydrocarbon multiple interactions EXP 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of CYP2C6V1 mRNA CTD PMID:30744511 chlorpromazine affects methylation ISO RGD:737416 6480464 CYP2C19 protein affects the methylation of Chlorpromazine CTD PMID:20615392 chlorpromazine decreases response to substance ISO RGD:737416 6480464 CYP2C19 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 chlorpromazine multiple interactions ISO RGD:737416 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine CTD PMID:23397584 chlorpromazine decreases activity ISO RGD:737416 6480464 Chlorpromazine results in decreased activity of CYP2C19 protein CTD PMID:15135088 chlorpyrifos increases expression ISO RGD:737416 6480464 Chlorpyrifos results in increased expression of CYP2C19 mRNA CTD PMID:16757081 , PMID:33011216 chlorpyrifos decreases expression ISO RGD:737416 6480464 Chlorpyrifos results in decreased expression of CYP2C19 protein CTD PMID:32194361 chlorpyrifos increases metabolic processing ISO RGD:737416 6480464 CYP2C19 results in increased metabolism of Chlorpyrifos CTD PMID:20709133 chlorpyrifos decreases activity ISO RGD:737416 6480464 CYP2C19 protein results in decreased activity of Chlorpyrifos CTD PMID:22281205 chlorpyrifos affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Chlorpyrifos CTD PMID:15764407 more ... chlorzoxazone affects metabolic processing EXP 6480464 CYP2C6V1 protein affects the metabolism of Chlorzoxazone CTD PMID:15879494 choline multiple interactions ISO RGD:1624096 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP2C38 mRNA CTD PMID:20938992 chrysosplenetin decreases activity ISO RGD:737416 6480464 chrysosplenetin results in decreased activity of CYP2C19 protein CTD PMID:29753067 citalopram decreases methylation ISO RGD:737416 6480464 CYP2C19 protein polymorphism results in decreased methylation of Citalopram, CYP2C19 protein results in decreased methylation of Citalopram analog CTD PMID:12975335 , PMID:9110356 Citreorosein increases chemical synthesis ISO RGD:737416 6480464 CYP2C19 protein results in increased chemical synthesis of 1 more ... CTD PMID:27989148 clopidogrel decreases metabolic processing ISO RGD:737416 6480464 CYP2C19 gene polymorphism results in decreased metabolism of clopidogrel, CYP2C19 gene SNP results in decreased metabolism of clopidogrel CTD PMID:17900275 , PMID:19106084 clopidogrel increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of clopidogrel CTD PMID:19812348 clopidogrel increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of clopidogrel CTD PMID:18532997 clopidogrel decreases response to substance ISO RGD:737416 6480464 CYP2C19 gene polymorphism results in decreased susceptibility to clopidogrel, CYP2C19 gene SNP results in decreased susceptibility to clopidogrel CTD PMID:17697139 more ... clopidogrel increases response to substance ISO RGD:737416 6480464 CYP2C19 gene polymorphism results in increased susceptibility to clopidogrel, CYP2C19 gene SNP results in increased susceptibility to clopidogrel CTD PMID:19496924 , PMID:20083681 clopidogrel affects abundance ISO RGD:737416 6480464 CYP2C19 gene polymorphism affects the abundance of clopidogrel metabolite CTD PMID:20217574 clopidogrel affects response to substance ISO RGD:737416 6480464 CYP2C19 gene affects the susceptibility to clopidogrel more ... CTD PMID:17900275 more ... clopidogrel multiple interactions ISO RGD:737416 6480464 ABCB1 gene affects the reaction [CYP2C19 gene affects the susceptibility to clopidogrel] more ... CTD PMID:16772608 more ... clotrimazole multiple interactions EXP 6480464 Clotrimazole inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 clozapine increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Clozapine CTD PMID:18809730 , PMID:27320963 clozapine multiple interactions ISO RGD:737416 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine CTD PMID:23397584 Clozapine N-oxide increases chemical synthesis ISO RGD:737416 6480464 CYP2C19 protein results in increased chemical synthesis of clozapine N-oxide CTD PMID:18809730 Clozapine N-oxide increases abundance ISO RGD:737416 6480464 CYP2C19 protein results in increased abundance of clozapine N-oxide CTD PMID:27320963 copper(II) chloride increases expression ISO RGD:1624096 6480464 cupric chloride results in increased expression of CYP2C38 mRNA CTD PMID:17211630 cumene hydroperoxide affects oxidation ISO RGD:737416 6480464 CYP2C19 protein affects the oxidation of cumene hydroperoxide CTD PMID:17478480 cyclophosphamide increases metabolic processing EXP 6480464 CYP2C6V1 results in increased metabolism of Cyclophosphamide CTD PMID:20566340 cyclophosphamide increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Cyclophosphamide CTD PMID:30500380 cyclophosphamide increases response to substance ISO RGD:737416 6480464 CYP2C19 protein results in increased susceptibility to Cyclophosphamide CTD PMID:30500380 cyclophosphamide increases activity ISO RGD:737416 6480464 CYP2C19 results in increased activity of Cyclophosphamide CTD PMID:9241661 cyclophosphamide increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Cyclophosphamide CTD PMID:16116487 cyclophosphamide multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide more ... CTD PMID:15248218 , PMID:30500380 cyclophosphamide decreases metabolic processing ISO RGD:737416 6480464 CYP2C19 gene polymorphism results in decreased metabolism of Cyclophosphamide CTD PMID:16116487 cyclosporin A decreases expression ISO RGD:737416 6480464 Cyclosporine results in decreased expression of CYP2C19 mRNA CTD PMID:20106945 cyclosporin A multiple interactions ISO RGD:737416 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Cyclosporine] results in decreased expression of CYP2C19 mRNA CTD PMID:33819548 cypermethrin increases expression ISO RGD:737416 6480464 cypermethrin results in increased expression of CYP2C19 mRNA CTD PMID:22310298 cyproconazole increases expression EXP 6480464 cyproconazole results in increased expression of CYP2C6V1 mRNA CTD PMID:25182419 cyproconazole increases expression ISO RGD:737416 6480464 cyproconazole results in increased expression of CYP2C19 protein CTD PMID:32194361 cyproconazole increases expression ISO RGD:1624096 6480464 cyproconazole results in increased expression of CYP2C38 protein CTD PMID:33150952 cyprodinil decreases expression ISO RGD:737416 6480464 cyprodinil results in decreased expression of CYP2C19 protein CTD PMID:32194361 dabrafenib decreases activity ISO RGD:737416 6480464 dabrafenib results in decreased activity of CYP2C19 protein CTD PMID:34780725 dapsone multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of and results in increased susceptibility to Dapsone CTD PMID:19998329 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of CYP2C6V1 mRNA CTD PMID:23914054 , PMID:32679240 dehydroepiandrosterone sulfate multiple interactions EXP 6480464 [Dehydroepiandrosterone Sulfate co-treated with Phenobarbital] results in increased expression of CYP2C6V1 protein CTD PMID:25786523 delavirdine decreases activity ISO RGD:737416 6480464 Delavirdine results in decreased activity of CYP2C19 protein CTD PMID:11225565 deoxycholic acid decreases expression EXP 6480464 Deoxycholic Acid results in decreased expression of CYP2C6V1 protein CTD PMID:10453939 deoxycholic acid multiple interactions ISO RGD:737416 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C19 mRNA more ... CTD PMID:33819548 deoxycholic acid multiple interactions EXP 6480464 Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of CYP2C6V1 protein] CTD PMID:10453939 desipramine decreases activity ISO RGD:737416 6480464 Desipramine results in decreased activity of CYP2C19 protein CTD PMID:15135088 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [Freund's Adjuvant results in decreased expression of CYP2C19 mRNA] CTD PMID:21149847 dexamethasone affects expression EXP 6480464 Dexamethasone affects the expression of CYP2C38 mRNA CTD PMID:15102944 dextran sulfate multiple interactions ISO RGD:1624096 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP2C38 mRNA CTD PMID:29950665 dextromethorphan affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Dextromethorphan CTD PMID:15286053 diarylheptanoid decreases activity ISO RGD:737416 6480464 Diarylheptanoids results in decreased activity of CYP2C19 protein CTD PMID:23850985 diazepam affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Diazepam CTD PMID:15286053 , PMID:15801540 diazepam affects metabolic processing EXP 6480464 CYP2C19 protein affects the metabolism of Diazepam CTD PMID:15801540 diazepam increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Diazepam CTD PMID:12464242 diazinon multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in decreased sulfation of and results in increased activity of Diazinon, CYP2C19 protein results in increased metabolism of and results in increased activity of Diazinon CTD PMID:11708902 , PMID:15764407 diazinon affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Diazinon CTD PMID:15764407 diazinon increases expression ISO RGD:737416 6480464 Diazinon results in increased expression of CYP2C19 mRNA CTD PMID:16757081 dibenzo[a,l]pyrene multiple interactions ISO RGD:737416 6480464 [Benzo(a)pyrene co-treated with dibenzo(a, l)pyrene] results in increased expression of CYP2C19 mRNA CTD PMID:17690111 dichloroacetic acid increases expression ISO RGD:1624096 6480464 Dichloroacetic Acid results in increased expression of CYP2C38 mRNA CTD PMID:28962523 diclofenac increases hydroxylation EXP 6480464 CYP2C6V1 protein results in increased hydroxylation of Diclofenac CTD PMID:11911841 diclofenac increases response to substance ISO RGD:737416 6480464 CYP2C19 protein results in increased susceptibility to Diclofenac CTD PMID:28762043 diclofenac increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Diclofenac CTD PMID:18511451 diclofenac multiple interactions ISO RGD:737416 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Diclofenac, [CYP2C19 protein co-treated with CYP2C9 protein] results in increased hydroxylation of Diclofenac CTD PMID:15486075 , PMID:23397584 diethylcarbamazine increases activity ISO RGD:737416 6480464 Diethylcarbamazine results in increased activity of CYP2C19 protein CTD PMID:11124226 diethyldithiocarbamic acid decreases activity ISO RGD:737416 6480464 Ditiocarb results in decreased activity of CYP2C19 protein CTD PMID:8819299 difenoconazole decreases expression ISO RGD:737416 6480464 difenoconazole results in decreased expression of CYP2C19 protein CTD PMID:32194361 dihydroartemisinin decreases activity ISO RGD:737416 6480464 artenimol results in decreased activity of CYP2C19 protein CTD PMID:11124226 dihydrocapsaicin decreases activity ISO RGD:737416 6480464 dihydrocapsaicin results in decreased activity of CYP2C19 protein CTD PMID:22375877 dimemorfan increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of dimemorfan CTD PMID:19593786 dimethomorph decreases expression ISO RGD:737416 6480464 dimethomorph results in decreased expression of CYP2C19 protein CTD PMID:32194361 dimethyl sulfoxide multiple interactions EXP 6480464 Dimethyl Sulfoxide inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 dimethyl sulfoxide multiple interactions ISO RGD:737416 6480464 [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C19 protein CTD PMID:35366062 diniconazole affects activity ISO RGD:737416 6480464 diniconazole affects the activity of CYP2C19 protein CTD PMID:23611293 diosmetin decreases activity ISO RGD:737416 6480464 diosmetin results in decreased activity of CYP2C19 protein CTD PMID:28867436 dronedarone increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of dronedarone CTD PMID:29616291 efavirenz decreases activity ISO RGD:737416 6480464 efavirenz results in decreased activity of CYP2C19 protein CTD PMID:11225565 Elemicin increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of elemicin CTD PMID:31468958 Elemicin multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of elemicin] which results in increased abundance of elemicin metabolite CTD PMID:31468958 ellipticine increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of ellipticine CTD PMID:22917556 emodin increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of Emodin CTD PMID:27989148 emodin decreases activity ISO RGD:737416 6480464 Emodin results in decreased activity of CYP2C19 protein CTD PMID:33438235 emodin multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite CTD PMID:27989148 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of CYP2C6V1 mRNA CTD PMID:29391264 enfuvirtide affects activity ISO RGD:737416 6480464 enfuvirtide affects the activity of CYP2C19 protein CTD PMID:15656696 enilconazole decreases expression ISO RGD:737416 6480464 enilconazole results in decreased expression of CYP2C19 mRNA, enilconazole results in decreased expression of CYP2C19 protein CTD PMID:32194361 , PMID:32201337 epoxiconazole increases expression EXP 6480464 epoxiconazole results in increased expression of CYP2C6V1 mRNA CTD PMID:25182419 epoxiconazole decreases expression ISO RGD:737416 6480464 epoxiconazole results in decreased expression of CYP2C19 protein CTD PMID:32194361 ethambutol decreases activity ISO RGD:737416 6480464 Ethambutol results in decreased activity of CYP2C19 protein CTD PMID:24910189 ethanol increases expression EXP 6480464 Ethanol results in increased expression of CYP2C6V1 mRNA CTD PMID:17920746 ethanol increases expression ISO RGD:1624096 6480464 Ethanol results in increased expression of CYP2C38 mRNA CTD PMID:19167417 ethofumesate decreases activity ISO RGD:737416 6480464 ethofumesate results in decreased activity of CYP2C19 protein CTD PMID:34147487 ethoprophos decreases expression ISO RGD:737416 6480464 ethoprop results in decreased expression of CYP2C19 protein CTD PMID:32194361 eupatorin decreases activity ISO RGD:737416 6480464 eupatorin results in decreased activity of CYP2C19 protein CTD PMID:21093571 famotidine multiple interactions ISO RGD:737416 6480464 Famotidine inhibits the reaction [CYP2C19 gene affects the susceptibility to Lansoprazole] CTD PMID:15963082 fenhexamid decreases expression ISO RGD:737416 6480464 N-(2, 3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of CYP2C19 protein CTD PMID:32194361 fenofibrate increases expression ISO RGD:737416 6480464 Fenofibrate results in increased expression of CYP2C19 mRNA CTD PMID:25572481 fenpyroximate decreases expression ISO RGD:737416 6480464 fenpyroximate results in decreased expression of CYP2C19 protein CTD PMID:32194361 fenvalerate increases expression ISO RGD:737416 6480464 fenvalerate results in increased expression of CYP2C19 mRNA CTD PMID:22310298 fipronil multiple interactions ISO RGD:737416 6480464 [fipronil co-treated with DEET] results in decreased expression of CYP2C19 mRNA CTD PMID:27091632 fluconazole decreases activity ISO RGD:737416 6480464 Fluconazole results in decreased activity of CYP2C19 protein CTD PMID:12464242 more ... fluconazole multiple interactions ISO RGD:737416 6480464 [Fluconazole results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole CTD PMID:26599973 fluconazole increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Fluconazole CTD PMID:17702393 fludioxonil decreases expression ISO RGD:737416 6480464 fludioxonil results in decreased expression of CYP2C19 protein CTD PMID:32194361 flunitrazepam increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Flunitrazepam CTD PMID:10911933 fluorescein (lactone form) multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein, Tranylcypromine inhibits the reaction [[CYP2C19 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein] CTD PMID:23850985 fluoxetine multiple interactions EXP 6480464 Fluoxetine inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 fluoxetine affects metabolic processing ISO RGD:737416 6480464 CYP2C19 gene polymorphism affects the metabolism of Fluoxetine, CYP2C19 protein affects the metabolism of Fluoxetine CTD PMID:11453896 , PMID:16236141 fluoxetine decreases activity ISO RGD:737416 6480464 Fluoxetine results in decreased activity of CYP2C19 protein CTD PMID:21915887 , PMID:22652334 fluoxetine multiple interactions ISO RGD:737416 6480464 Fluoxetine inhibits the reaction [CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin] more ... CTD PMID:11752104 more ... fluoxetine increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Fluoxetine CTD PMID:11453896 , PMID:11752104 fluphenazine decreases activity ISO RGD:737416 6480464 Fluphenazine results in decreased activity of CYP2C19 protein CTD PMID:15135088 flusilazole decreases expression ISO RGD:737416 6480464 flusilazole results in decreased expression of CYP2C19 protein CTD PMID:32194361 flutamide multiple interactions ISO RGD:737416 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Flutamide CTD PMID:23397584 flutamide increases response to substance ISO RGD:737416 6480464 CYP2C19 protein results in increased susceptibility to Flutamide CTD PMID:28762043 fluxapyroxad decreases expression ISO RGD:737416 6480464 fluxapyroxad results in decreased expression of CYP2C19 protein CTD PMID:32194361 folic acid multiple interactions ISO RGD:1624096 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP2C38 mRNA CTD PMID:20938992 Furafylline multiple interactions ISO RGD:737416 6480464 furafylline inhibits the reaction [CYP2C19 protein results in increased oxidation of 4-amino-2-phenoxymethanesulfonanilide] CTD PMID:19053182 Furafylline decreases activity EXP 6480464 furafylline results in decreased activity of CYP2C6V1 protein CTD PMID:15879494 furan decreases expression EXP 6480464 furan results in decreased expression of CYP2C6V1 mRNA CTD PMID:25539665 , PMID:26194646 genistein increases hydroxylation EXP 6480464 CYP2C6V1 protein results in increased hydroxylation of Genistein CTD PMID:15587933 genistein decreases activity ISO RGD:737416 6480464 Genistein results in decreased activity of CYP2C19 protein CTD PMID:29753067 gingerol increases response to substance ISO RGD:737416 6480464 CYP2C19 mRNA results in increased susceptibility to gingerol CTD PMID:29555536 glutathione multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac more ... CTD PMID:24246759 more ... glycochenodeoxycholic acid multiple interactions ISO RGD:737416 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C19 mRNA more ... CTD PMID:33819548 glycocholic acid multiple interactions ISO RGD:737416 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C19 mRNA more ... CTD PMID:33819548 glycodeoxycholic acid multiple interactions ISO RGD:737416 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C19 mRNA more ... CTD PMID:33819548 glyoxal multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of and results in increased susceptibility to sudoxicam] which results in increased chemical synthesis of Glyoxal CTD PMID:33253783 herbicide multiple interactions ISO RGD:737416 6480464 [CYP1A1 protein co-treated with CYP2B6 protein co-treated with CYP2C19 protein] results in decreased susceptibility to Herbicides CTD PMID:16608219 heroin increases activity ISO RGD:1624096 6480464 Heroin results in increased activity of CYP2C19 protein CTD PMID:35914676 hesperetin decreases activity ISO RGD:737416 6480464 hesperetin results in decreased activity of CYP2C19 protein CTD PMID:29753067 hexobarbital increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Hexobarbital CTD PMID:12464242 Hydroxymephenytoin increases chemical synthesis ISO RGD:737416 6480464 CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin CTD PMID:12401345 more ... Hydroxymephenytoin multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased hydroxylation of Mephenytoin] which results in increased chemical synthesis of 4-hydroxymephenytoin more ... CTD PMID:21915887 more ... Hypaconitine increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of hypaconitine CTD PMID:21550385 ifosfamide increases response to substance ISO RGD:737416 6480464 CYP2C19 protein results in increased susceptibility to Ifosfamide CTD PMID:20507880 ifosfamide increases activity ISO RGD:737416 6480464 CYP2C19 results in increased activity of Ifosfamide CTD PMID:9241661 imipramine affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Imipramine CTD PMID:15286053 imipramine multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in decreased methylation of and results in increased activity of Imipramine, Organophosphorus Compounds inhibits the reaction [CYP2C19 protein results in decreased methylation of and results in increased activity of Imipramine] CTD PMID:15922009 imipramine oxide increases abundance ISO RGD:737416 6480464 CYP2C19 protein results in increased abundance of imipramine N-oxide CTD PMID:27320963 imiquimod increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Imiquimod CTD PMID:31111189 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of CYP2C6V1 mRNA CTD PMID:21396975 indole-3-methanol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP2C6V1 mRNA CTD PMID:22129741 iprodione decreases expression ISO RGD:737416 6480464 iprodione results in decreased expression of CYP2C19 protein CTD PMID:32194361 isocarbophos multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of and results in decreased sulfation of and affects the activity of isocarbophos CTD PMID:24752505 isoliquiritigenin decreases activity ISO RGD:737416 6480464 isoliquiritigenin results in decreased activity of CYP2C19 protein CTD PMID:29753067 ketoconazole multiple interactions EXP 6480464 Ketoconazole inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 ketoconazole multiple interactions ISO RGD:737416 6480464 Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 ketoconazole decreases activity ISO RGD:737416 6480464 Ketoconazole results in decreased activity of CYP2C19 protein CTD PMID:14709627 , PMID:15618748 ketoconazole decreases activity EXP 6480464 Ketoconazole results in decreased activity of CYP2C6V1 protein CTD PMID:12814958 , PMID:15879494 L-methionine multiple interactions ISO RGD:1624096 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP2C38 mRNA CTD PMID:20938992 lamotrigine increases glutathionylation EXP 6480464 CYP2C6V1 protein results in increased glutathionylation of lamotrigine CTD PMID:19961160 lansoprazole decreases metabolic processing ISO RGD:737416 6480464 CYP2C19 gene polymorphism results in decreased metabolism of Lansoprazole CTD PMID:19814645 lansoprazole decreases activity ISO RGD:737416 6480464 Lansoprazole results in decreased activity of CYP2C19 protein CTD PMID:21795468 lansoprazole affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Lansoprazole CTD PMID:15010519 lansoprazole increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Lansoprazole, Lansoprazole results in increased metabolism of CYP2C19 protein CTD PMID:21212520 , PMID:8930576 lansoprazole increases expression EXP 6480464 Lansoprazole results in increased expression of CYP2C6V1 mRNA, Lansoprazole results in increased expression of CYP2C6V1 protein CTD PMID:14550749 , PMID:9152597 lansoprazole increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Lansoprazole CTD PMID:11829200 more ... lansoprazole multiple interactions ISO RGD:737416 6480464 CYP2C19 affects the reaction [Lansoprazole affects the susceptibility to Tacrolimus] more ... CTD PMID:15010519 more ... lansoprazole affects response to substance ISO RGD:737416 6480464 CYP2C19 gene affects the susceptibility to Lansoprazole, CYP2C19 gene polymorphism affects the susceptibility to Lansoprazole CTD PMID:11929404 more ... lefetamine decreases alkylation ISO RGD:737416 6480464 CYP2C19 protein results in decreased alkylation of lephetamine CTD PMID:26276083 Licochalcone A decreases activity ISO RGD:737416 6480464 licochalcone A results in decreased activity of CYP2C19 protein CTD PMID:26100226 linoleic acid decreases activity ISO RGD:737416 6480464 Linoleic Acid results in decreased activity of CYP2C19 protein CTD PMID:16978661 linoleic acid multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of [Linoleic Acid co-treated with NADP] CTD PMID:16978661 lipoic acid multiple interactions ISO RGD:737416 6480464 Thioctic Acid inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 liquiritigenin decreases activity ISO RGD:737416 6480464 liquiritigenin results in decreased activity of CYP2C19 protein CTD PMID:29753067 lithocholic acid multiple interactions EXP 6480464 [CYP2C6V1 protein results in increased metabolism of Lithocholic Acid] which results in increased chemical synthesis of Lithocholic Acid analog CTD PMID:18039809 lithocholic acid increases metabolic processing EXP 6480464 CYP2C6V1 protein results in increased metabolism of Lithocholic Acid CTD PMID:18039809 luteolin decreases activity ISO RGD:737416 6480464 Luteolin results in decreased activity of CYP2C19 protein CTD PMID:29753067 madecassoside decreases activity ISO RGD:737416 6480464 madecassoside results in decreased activity of CYP2C19 protein CTD PMID:21349323 maneb decreases expression ISO RGD:737416 6480464 Maneb results in decreased expression of CYP2C19 protein CTD PMID:32194361 mangiferin decreases activity EXP 6480464 mangiferin results in decreased activity of CYP2C6V1 protein CTD PMID:18053976 Marrubiin increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of marrubiin CTD PMID:34431289 mefenamic acid increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Mefenamic Acid CTD PMID:25372302 Melarsoprol decreases activity ISO RGD:737416 6480464 Melarsoprol results in decreased activity of CYP2C19 protein CTD PMID:11124226 melatonin increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Melatonin CTD PMID:15616152 melatonin decreases methylation ISO RGD:737416 6480464 CYP2C19 protein results in decreased methylation of Melatonin CTD PMID:15616152 mephenytoin multiple interactions ISO RGD:737416 6480464 4-amino-2-phenoxymethanesulfonanilide inhibits the reaction [CYP2C19 protein results in increased oxidation of Mephenytoin] more ... CTD PMID:11502731 more ... mephenytoin decreases activity ISO RGD:737416 6480464 Mephenytoin results in decreased activity of CYP2C19 protein CTD PMID:12467917 mephenytoin affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Mephenytoin CTD PMID:3577206 mephenytoin increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Mephenytoin CTD PMID:11907490 more ... mephenytoin increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of Mephenytoin CTD PMID:17478480 more ... mephenytoin affects hydroxylation ISO RGD:737416 6480464 CYP2C19 gene SNP affects the hydroxylation of Mephenytoin, CYP2C19 protein affects the hydroxylation of Mephenytoin CTD PMID:9170147 mephenytoin increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Mephenytoin, CYP2C19 protein results in increased hydroxylation of Mephenytoin analog CTD PMID:12433797 more ... mephobarbital increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Mephobarbital CTD PMID:12464242 Meprobamate multiple interactions ISO RGD:737416 6480464 [CYP2C19 gene polymorphism affects the metabolism of Carisoprodol] which affects the chemical synthesis of Meprobamate, [CYP2C19 protein results in increased metabolism of Carisoprodol] which results in increased chemical synthesis of Meprobamate CTD PMID:12835613 , PMID:22527345 mercury dichloride increases expression ISO RGD:1624096 6480464 Mercuric Chloride results in increased expression of CYP2C38 mRNA CTD PMID:24472606 metalaxyl decreases expression ISO RGD:737416 6480464 metalaxyl results in decreased expression of CYP2C19 protein CTD PMID:32194361 methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of CYP2C6V1 mRNA CTD PMID:30047161 methiocarb increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Methiocarb CTD PMID:27665777 methiocarb multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of Methiocarb] which results in increased abundance of methiocarb sulfoxide CTD PMID:27665777 methiocarb-sulfoxide multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of Methiocarb] which results in increased abundance of methiocarb sulfoxide CTD PMID:27665777 methiocarb-sulfoxide increases abundance ISO RGD:737416 6480464 CYP2C19 protein results in increased abundance of methiocarb sulfoxide CTD PMID:27665777 methoxsalen decreases activity EXP 6480464 Methoxsalen results in decreased activity of CYP2C6V1 protein CTD PMID:12814958 , PMID:15879494 methoxychlor multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein co-treated with CYP2C9 protein] results in decreased methylation of Methoxychlor CTD PMID:15486075 methoxychlor increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Methoxychlor CTD PMID:9714305 methoxychlor decreases methylation ISO RGD:737416 6480464 CYP2C19 protein results in decreased methylation of Methoxychlor CTD PMID:12167570 more ... methylmercury chloride multiple interactions EXP 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of CYP2C6V1 mRNA CTD PMID:30744511 Methysticin decreases activity EXP 6480464 methysticin results in decreased activity of CYP2C19 protein CTD PMID:16033948 metolachlor multiple interactions ISO RGD:737416 6480464 [CYP1A1 protein co-treated with CYP2B6 protein co-treated with CYP2C19 protein] results in decreased susceptibility to [norflurazone co-treated with metolachlor co-treated with Atrazine], [CYP1A1 protein co-treated with CYP2B6 protein co-treated with CYP2C19 protein] results in decreased susceptibility to metolachlor CTD PMID:16608219 miconazole decreases activity ISO RGD:737416 6480464 Miconazole results in decreased activity of CYP2C19 protein CTD PMID:21349323 Miltirone decreases activity ISO RGD:737416 6480464 miltirone results in decreased activity of CYP2C19 protein CTD PMID:25686904 Mitragynine decreases activity ISO RGD:737416 6480464 mitragynine results in decreased activity of CYP2C19 protein CTD PMID:31707106 moclobemide increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Moclobemide CTD PMID:12464242 mono(2-ethyl-5-hydroxyhexyl) phthalate multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate CTD PMID:22186153 mono(2-ethyl-5-hydroxyhexyl) phthalate multiple interactions EXP 6480464 [CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate CTD PMID:22186153 , PMID:23545481 mono(2-ethyl-5-oxohexyl) phthalate multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate CTD PMID:22186153 mono(2-ethyl-5-oxohexyl) phthalate multiple interactions EXP 6480464 [CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate CTD PMID:22186153 , PMID:23545481 mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate more ... CTD PMID:22186153 , PMID:23545481 mono(2-ethylhexyl) phthalate multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate, [CYP2C19 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate CTD PMID:22186153 mono(2-ethylhexyl) phthalate increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate CTD PMID:22186153 mono(2-ethylhexyl) phthalate increases metabolic processing EXP 6480464 CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate CTD PMID:22186153 , PMID:23545481 monocrotaline multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of and results in increased activity of Monocrotaline CTD PMID:19818743 morphine increases activity ISO RGD:1624096 6480464 Morphine results in increased activity of CYP2C19 protein CTD PMID:35914676 myricetin decreases activity ISO RGD:737416 6480464 myricetin results in decreased activity of CYP2C19 protein CTD PMID:29753067 N,N-diethyl-m-toluamide increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of DEET CTD PMID:11854147 N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in increased methylation of CYP2C6V1 gene CTD PMID:33148267 N,N-diethyl-m-toluamide multiple interactions ISO RGD:737416 6480464 [fipronil co-treated with DEET] results in decreased expression of CYP2C19 mRNA CTD PMID:27091632 N,N-diisopropyltryptamine decreases activity ISO RGD:737416 6480464 N, N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein CTD PMID:26599973 N,N-diisopropyltryptamine multiple interactions ISO RGD:737416 6480464 [N, N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole CTD PMID:26599973 N,N-dimethyltryptamine increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of N, N-Dimethyltryptamine CTD PMID:27320963 N-acetyl-L-cysteine multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite CTD PMID:27989148 N-desmethylclozapine increases chemical synthesis ISO RGD:737416 6480464 CYP2C19 protein results in increased chemical synthesis of norclozapine CTD PMID:18809730 N-hydroxy-PhIP multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:17279779 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C6V1 protein more ... CTD PMID:16246485 more ... N-nitrosodiethylamine decreases expression ISO RGD:1624096 6480464 Diethylnitrosamine results in decreased expression of CYP2C38 mRNA CTD PMID:24535843 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of CYP2C6V1 mRNA CTD PMID:20360939 NADP zwitterion multiple interactions ISO RGD:737416 6480464 [2 more ... CTD PMID:16978661 more ... NADP(+) multiple interactions ISO RGD:737416 6480464 [2 more ... CTD PMID:16978661 more ... naphthalene increases expression ISO RGD:737416 6480464 naphthalene results in increased expression of CYP2C19 mRNA CTD PMID:20500019 nefazodone multiple interactions ISO RGD:737416 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP2C19 mRNA CTD PMID:33819548 nicardipine decreases activity ISO RGD:737416 6480464 Nicardipine results in decreased activity of CYP2C19 protein CTD PMID:10805063 , PMID:15863898 nimesulide increases glutathionylation ISO RGD:737416 6480464 CYP2C19 protein results in increased glutathionylation of nimesulide CTD PMID:26524229 norflurazon multiple interactions ISO RGD:737416 6480464 [CYP1A1 protein co-treated with CYP2B6 protein co-treated with CYP2C19 protein] results in decreased susceptibility to [norflurazone co-treated with metolachlor co-treated with Atrazine], [CYP1A1 protein co-treated with CYP2B6 protein co-treated with CYP2C19 protein] results in decreased susceptibility to norflurazone CTD PMID:16608219 norgestimate multiple interactions ISO RGD:737416 6480464 [Ethinyl Estradiol co-treated with norgestimate] results in decreased activity of CYP2C19 protein CTD PMID:16291717 Notopterol increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of notopterol CTD PMID:32198085 Notopterol multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of notopterol] promotes the reaction [Glutathione binds to notopterol] CTD PMID:32198085 O-methyleugenol decreases expression ISO RGD:737416 6480464 methyleugenol results in decreased expression of CYP2C19 mRNA CTD PMID:32234424 o-toluidine increases expression ISO RGD:1624096 6480464 2-toluidine results in increased expression of CYP2C19 protein CTD PMID:36870411 okanin decreases activity ISO RGD:737416 6480464 okanin results in decreased activity of CYP2C19 protein CTD PMID:29753067 omeprazole affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Omeprazole CTD PMID:14586384 more ... omeprazole decreases metabolic processing ISO RGD:737416 6480464 CYP2C19 gene alternative form results in decreased metabolism of Omeprazole CTD PMID:20573087 omeprazole decreases activity ISO RGD:737416 6480464 Omeprazole results in decreased activity of CYP2C19 protein CTD PMID:15306208 more ... omeprazole multiple interactions ISO RGD:737416 6480464 [5-bromotryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole more ... CTD PMID:11752104 more ... omeprazole increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Omeprazole CTD PMID:12637241 more ... omeprazole increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Omeprazole CTD PMID:11752104 more ... organophosphorus compound multiple interactions ISO RGD:737416 6480464 Organophosphorus Compounds inhibits the reaction [CYP2C19 protein results in decreased methylation of and results in increased activity of Imipramine] CTD PMID:15922009 orotic acid decreases expression EXP 6480464 Orotic Acid results in decreased expression of CYP2C6V1 protein CTD PMID:25786523 oxymetazoline multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein co-treated with NADP] results in increased metabolism of Oxymetazoline CTD PMID:21177487 ozone multiple interactions ISO RGD:1624096 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of CYP2C38 mRNA CTD PMID:27106289 p-tert-Amylphenol increases response to substance ISO RGD:737416 6480464 CYP2C19 gene SNP results in increased susceptibility to 4-tert-octylphenol CTD PMID:23555028 pantoprazole decreases activity ISO RGD:737416 6480464 pantoprazole results in decreased activity of CYP2C19 protein CTD PMID:21795468 pantoprazole affects response to substance ISO RGD:737416 6480464 CYP2C19 gene polymorphism affects the susceptibility to pantoprazole CTD PMID:20223877 pantoprazole increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of pantoprazole CTD PMID:8930576 pantoprazole multiple interactions ISO RGD:737416 6480464 pantoprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin] CTD PMID:15258107 paracetamol decreases expression ISO RGD:737416 6480464 Acetaminophen results in decreased expression of CYP2C19 mRNA CTD PMID:29067470 paracetamol multiple interactions ISO RGD:737416 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of CYP2C19 mRNA CTD PMID:33819548 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of CYP2C6V1 mRNA CTD PMID:16328009 parathion affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Parathion CTD PMID:12669189 , PMID:17079358 PCB138 multiple interactions ISO RGD:1624096 6480464 [2 more ... CTD PMID:25510870 pedalitin decreases activity ISO RGD:737416 6480464 pedalitin results in decreased activity of CYP2C19 protein CTD PMID:29753067 pentamidine decreases activity ISO RGD:737416 6480464 Pentamidine results in decreased activity of CYP2C19 protein CTD PMID:11124226 perfluorobutanesulfonic acid decreases activity ISO RGD:737416 6480464 perfluorobutanesulfonic acid results in decreased activity of CYP2C19 protein CTD PMID:35121066 perfluorodecanoic acid decreases activity ISO RGD:737416 6480464 perfluorodecanoic acid results in decreased activity of CYP2C19 protein CTD PMID:35121066 perfluoroheptanoic acid decreases activity ISO RGD:737416 6480464 perfluoro-n-heptanoic acid results in decreased activity of CYP2C19 protein CTD PMID:35121066 perfluorohexanesulfonic acid decreases activity ISO RGD:737416 6480464 perfluorohexanesulfonic acid results in decreased activity of CYP2C19 protein CTD PMID:35121066 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of CYP2C6V1 mRNA CTD PMID:21723365 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:737416 6480464 perfluorooctane sulfonic acid results in decreased expression of CYP2C19 mRNA CTD PMID:31809754 perfluorooctane-1-sulfonic acid increases expression ISO RGD:1624096 6480464 perfluorooctane sulfonic acid results in increased expression of CYP2C38 mRNA CTD PMID:20936131 perfluorooctane-1-sulfonic acid decreases activity ISO RGD:737416 6480464 perfluorooctane sulfonic acid results in decreased activity of CYP2C19 protein CTD PMID:31809754 , PMID:35121066 perfluorooctane-1-sulfonic acid increases expression ISO RGD:737416 6480464 perfluorooctane sulfonic acid results in increased expression of CYP2C19 mRNA CTD PMID:21723365 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:737416 6480464 perfluorooctane sulfonic acid inhibits the reaction [CYP2C19 protein results in increased oxidation of Mephenytoin] CTD PMID:21964418 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of CYP2C6V1 mRNA CTD PMID:21723365 , PMID:28511854 perfluorooctanoic acid decreases activity ISO RGD:737416 6480464 perfluorooctanoic acid results in decreased activity of CYP2C19 protein CTD PMID:31809754 , PMID:35121066 perfluorooctanoic acid decreases expression ISO RGD:737416 6480464 perfluorooctanoic acid results in decreased expression of CYP2C19 mRNA CTD PMID:31809754 perhexiline multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of [perhexiline maleate results in increased abundance of Perhexiline], CYP2C19 protein results in increased metabolism of [perhexiline maleate results in increased abundance of Perhexiline] CTD PMID:36083301 permethrin increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Permethrin CTD PMID:24548679 permethrin multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in increased methylation of CYP2C6V1 gene CTD PMID:33148267 phenacetin affects metabolic processing EXP 6480464 CYP2C6V1 protein affects the metabolism of Phenacetin CTD PMID:15231049 , PMID:15879494 phenacetin decreases ethylation EXP 6480464 CYP2C6V1 protein results in decreased ethylation of Phenacetin CTD PMID:11911841 phencyclidine affects oxidation ISO RGD:737416 6480464 CYP2C19 protein affects the oxidation of Phencyclidine CTD PMID:16782764 phencyclidine decreases activity ISO RGD:737416 6480464 Phencyclidine results in decreased activity of CYP2C19 protein CTD PMID:16782764 phenobarbital multiple interactions EXP 6480464 [Dehydroepiandrosterone Sulfate co-treated with Phenobarbital] results in increased expression of CYP2C6V1 protein more ... CTD PMID:25786523 more ... phenobarbital decreases expression ISO RGD:1624096 6480464 Phenobarbital results in decreased expression of CYP2C38 mRNA CTD PMID:19270015 more ... phenobarbital multiple interactions ISO RGD:1624096 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CYP2C38 mRNA] CTD PMID:19482888 phenobarbital increases expression ISO RGD:1624096 6480464 Phenobarbital results in increased expression of CYP2C38 mRNA CTD PMID:19482888 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of CYP2C6V1 mRNA, Phenobarbital results in increased expression of CYP2C6V1 protein CTD PMID:10506011 more ... phenobarbital increases activity ISO RGD:737416 6480464 Phenobarbital results in increased activity of CYP2C19 protein CTD PMID:19328226 phenobarbital affects expression ISO RGD:737416 6480464 Phenobarbital affects the expression of CYP2C19 mRNA CTD PMID:19084549 phenobarbital increases expression ISO RGD:737416 6480464 Phenobarbital results in increased expression of CYP2C19 mRNA more ... CTD PMID:15629111 more ... phenobarbital increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Phenobarbital CTD PMID:16789993 phenobarbital decreases metabolic processing ISO RGD:737416 6480464 CYP2C19 gene polymorphism results in decreased metabolism of Phenobarbital CTD PMID:16789993 phenobarbital increases activity EXP 6480464 Phenobarbital results in increased activity of CYP2C6V1 protein CTD PMID:16781091 phenytoin increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Phenytoin CTD PMID:9860067 phenytoin increases metabolic processing EXP 6480464 CYP2C19 protein results in increased metabolism of Phenytoin CTD PMID:15569425 phenytoin decreases hydroxylation ISO RGD:737416 6480464 CYP2C19 gene polymorphism results in decreased hydroxylation of Phenytoin CTD PMID:9860067 phenytoin multiple interactions ISO RGD:737416 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Phenytoin CTD PMID:23397584 phenytoin affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Phenytoin CTD PMID:15855726 phenytoin increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Phenytoin CTD PMID:16220110 more ... phenytoin decreases metabolic processing ISO RGD:737416 6480464 CYP2C19 gene polymorphism results in decreased metabolism of Phenytoin CTD PMID:16789993 more ... PhIP increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine CTD PMID:17279779 PhIP multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:17279779 phthalic acid multiple interactions EXP 6480464 [CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of phthalic acid CTD PMID:23545481 physcion increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of physcione CTD PMID:29667811 picoxystrobin decreases activity ISO RGD:737416 6480464 picoxystrobin results in decreased activity of CYP2C19 protein CTD PMID:23611293 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of CYP2C6V1 mRNA CTD PMID:16940010 pirinixic acid increases expression ISO RGD:1624096 6480464 pirinixic acid results in increased expression of CYP2C38 mRNA CTD PMID:18301758 pirinixic acid multiple interactions ISO RGD:1624096 6480464 PPARA protein affects the reaction [pirinixic acid results in decreased expression of CYP2C38 mRNA] CTD PMID:17405874 pirinixic acid decreases expression ISO RGD:1624096 6480464 pirinixic acid results in decreased expression of CYP2C38 mRNA CTD PMID:17405874 poly(I:C) decreases expression EXP 6480464 Poly I-C results in decreased expression of CYP2C6V1 mRNA CTD PMID:23939143 pomalidomide increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of pomalidomide CTD PMID:24350712 prednisolone multiple interactions EXP 6480464 Prednisolone inhibits the reaction [Freund's Adjuvant results in decreased expression of CYP2C19 mRNA] CTD PMID:21149847 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:1624096 6480464 Pregnenolone Carbonitrile results in decreased expression of CYP2C38 mRNA CTD PMID:28903501 prochloraz decreases expression ISO RGD:737416 6480464 prochloraz results in decreased expression of CYP2C19 protein CTD PMID:32194361 profenofos multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased metabolism of profenofos] which results in increased abundance of 4-bromo-2-chlorophenol CTD PMID:23415833 profenofos increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of profenofos CTD PMID:23415833 progesterone increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Progesterone CTD PMID:18957504 proguanil increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Proguanil CTD PMID:12464242 proguanil decreases activity ISO RGD:737416 6480464 Proguanil results in decreased activity of CYP2C19 protein CTD PMID:11124226 propiconazole decreases expression ISO RGD:737416 6480464 propiconazole results in decreased expression of CYP2C19 protein CTD PMID:32194361 propranolol increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of Propranolol CTD PMID:19853591 propranolol affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Propranolol CTD PMID:15286053 pterostilbene decreases activity ISO RGD:737416 6480464 pterostilbene results in decreased activity of CYP2C19 protein CTD PMID:30394306 purpurin decreases activity ISO RGD:737416 6480464 purpurin results in decreased activity of CYP2C19 protein CTD PMID:33438235 pyrene affects expression EXP 6480464 pyrene affects the expression of CYP2C6V1 mRNA CTD PMID:30240548 pyrrolidines affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Pyrrolidines CTD PMID:21053377 quercetin multiple interactions ISO RGD:737416 6480464 Quercetin inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 quercetin decreases activity ISO RGD:737416 6480464 Quercetin results in decreased activity of CYP2C19 protein CTD PMID:29753067 quinidine decreases activity EXP 6480464 Quinidine results in decreased activity of CYP2C6V1 protein CTD PMID:12814958 quinidine multiple interactions ISO RGD:737416 6480464 Quinidine affects the reaction [CYP2C19 protein results in increased oxidation of 4-amino-2-phenoxymethanesulfonanilide] CTD PMID:19053182 quinine decreases activity EXP 6480464 Quinine results in decreased activity of CYP2C6V1 protein CTD PMID:12814958 , PMID:15879494 quinine decreases activity ISO RGD:737416 6480464 Quinine results in decreased activity of CYP2C19 protein CTD PMID:11124226 rabeprazole multiple interactions ISO RGD:737416 6480464 CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole] CTD PMID:17377957 rabeprazole affects response to substance ISO RGD:737416 6480464 CYP2C19 gene affects the susceptibility to Rabeprazole CTD PMID:15903128 resveratrol multiple interactions ISO RGD:737416 6480464 resveratrol inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin] CTD PMID:12569440 resveratrol multiple interactions ISO RGD:1624096 6480464 Resveratrol inhibits the reaction [titanium dioxide results in increased expression of CYP2C38 mRNA] CTD PMID:31298478 resveratrol decreases activity ISO RGD:737416 6480464 resveratrol results in decreased activity of CYP2C19 protein CTD PMID:12569440 Retrorsine multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of and results in increased activity of retrorsine CTD PMID:19818743 Rhein decreases activity ISO RGD:737416 6480464 rhein results in decreased activity of CYP2C19 protein CTD PMID:33438235 rifampicin increases expression ISO RGD:737416 6480464 Rifampin results in increased expression of CYP2C19 mRNA, Rifampin results in increased expression of CYP2C19 protein CTD PMID:12584154 more ... rifampicin multiple interactions ISO RGD:737416 6480464 Rifampin results in increased expression of and results in increased activity of CYP2C19 protein CTD PMID:14709624 rifampicin increases activity ISO RGD:737416 6480464 Rifampin results in increased activity of CYP2C19 protein CTD PMID:22126990 ritonavir increases expression ISO RGD:737416 6480464 Ritonavir results in increased expression of CYP2C19 mRNA CTD PMID:11918509 rubiadin decreases activity ISO RGD:737416 6480464 rubiadin results in decreased activity of CYP2C19 protein CTD PMID:33438235 sertraline increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Sertraline CTD PMID:11452243 sertraline decreases methylation ISO RGD:737416 6480464 CYP2C19 protein results in decreased methylation of Sertraline CTD PMID:11452243 sertraline multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in decreased amination of and results in increased metabolism of Sertraline, CYP2C19 protein results in decreased methylation of and results in increased metabolism of Sertraline CTD PMID:15547048 sertraline affects metabolic processing ISO RGD:737416 6480464 CYP2C19 gene polymorphism affects the metabolism of Sertraline CTD PMID:11452243 sibutramine decreases activity ISO RGD:737416 6480464 sibutramine results in decreased activity of CYP2C19 protein CTD PMID:23777987 sodium arsenite increases expression ISO RGD:1624096 6480464 sodium arsenite results in increased expression of CYP2C38 mRNA CTD PMID:25065748 sodium arsenite decreases expression ISO RGD:737416 6480464 sodium arsenite results in decreased expression of CYP2C19 mRNA CTD PMID:29301061 sophoranone decreases activity ISO RGD:737416 6480464 sophoranone results in decreased activity of CYP2C19 protein CTD PMID:29753067 Sudan I increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of 1-phenylazo-2-naphthol CTD PMID:17159775 Sudan I multiple interactions ISO RGD:737416 6480464 CYB5A protein inhibits the reaction [CYP2C19 protein results in increased oxidation of 1-phenylazo-2-naphthol] CTD PMID:17159775 sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of CYP2C6V1 mRNA CTD PMID:30047161 sulfaphenazole decreases activity EXP 6480464 Sulfaphenazole results in decreased activity of CYP2C6V1 protein CTD PMID:12814958 sulfaphenazole multiple interactions ISO RGD:737416 6480464 Sulfaphenazole inhibits the reaction [CYP2C19 protein results in increased metabolism of triflumuron] CTD PMID:31082524 sulfasalazine increases expression ISO RGD:1624096 6480464 Sulfasalazine results in increased expression of CYP2C38 mRNA CTD PMID:31830553 Sunset Yellow FCF multiple interactions ISO RGD:737416 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C19 mRNA CTD PMID:33819548 suramin decreases activity ISO RGD:737416 6480464 Suramin results in decreased activity of CYP2C19 protein CTD PMID:11124226 tacrolimus hydrate multiple interactions ISO RGD:737416 6480464 CYP2C19 affects the reaction [Lansoprazole affects the susceptibility to Tacrolimus] more ... CTD PMID:15010519 more ... tamoxifen increases response to substance ISO RGD:737416 6480464 CYP2C19 gene polymorphism results in increased susceptibility to Tamoxifen CTD PMID:21047200 tamoxifen increases activity ISO RGD:737416 6480464 Tamoxifen metabolite results in increased activity of CYP2C19 protein CTD PMID:29285606 tamoxifen increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Tamoxifen CTD PMID:29285606 tamoxifen multiple interactions ISO RGD:737416 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Tamoxifen more ... CTD PMID:23397584 , PMID:29285606 Tanshinone I decreases activity ISO RGD:737416 6480464 tanshinone results in decreased activity of CYP2C19 protein CTD PMID:25686904 tert-butyl ethyl ether increases expression EXP 6480464 ethyl tert-butyl ether results in increased expression of CYP2C6V1 mRNA, ethyl tert-butyl ether results in increased expression of CYP2C6V1 protein CTD PMID:24090815 testosterone decreases expression ISO RGD:1624096 6480464 Testosterone results in decreased expression of CYP2C38 mRNA CTD PMID:21669218 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of CYP2C6V1 protein CTD PMID:17606319 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of CYP2C6V1 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2C6V1 mRNA] CTD PMID:31150632 tetrachloromethane decreases expression ISO RGD:1624096 6480464 Carbon Tetrachloride results in decreased expression of CYP2C38 mRNA CTD PMID:25270620 more ... tetraconazole affects activity ISO RGD:737416 6480464 tetraconazole affects the activity of CYP2C19 protein CTD PMID:23611293 tetracycline increases expression ISO RGD:1624096 6480464 Tetracycline results in increased expression of CYP2C38 mRNA CTD PMID:16917069 thalidomide multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5'-hydroxythalidomide more ... CTD PMID:20443640 , PMID:24350712 thalidomide increases oxidation ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of Thalidomide CTD PMID:24350712 thalidomide increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Thalidomide CTD PMID:20443640 thiacloprid increases expression ISO RGD:737416 6480464 thiacloprid results in increased expression of CYP2C19 mRNA CTD PMID:32201337 thiacloprid decreases expression ISO RGD:737416 6480464 thiacloprid results in decreased expression of CYP2C19 protein CTD PMID:32194361 thiamethoxam decreases expression ISO RGD:737416 6480464 Thiamethoxam results in decreased expression of CYP2C19 protein CTD PMID:32194361 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2C6V1 mRNA CTD PMID:28943392 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of CYP2C6V1 mRNA CTD PMID:34492290 thioridazine multiple interactions ISO RGD:737416 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Thioridazine CTD PMID:23397584 thioridazine decreases activity ISO RGD:737416 6480464 Thioridazine results in decreased activity of CYP2C19 protein CTD PMID:15135088 thiram decreases expression ISO RGD:737416 6480464 Thiram results in decreased expression of CYP2C19 protein CTD PMID:32194361 ticlopidine multiple interactions ISO RGD:737416 6480464 CYP2C19 protein results in increased oxidation of and results in increased cleavage of Ticlopidine metabolite more ... CTD PMID:16049126 more ... ticlopidine decreases activity ISO RGD:737416 6480464 Ticlopidine results in decreased activity of CYP2C19 protein CTD PMID:10759690 more ... titanium dioxide increases expression ISO RGD:1624096 6480464 titanium dioxide results in increased expression of CYP2C38 mRNA CTD PMID:31298478 titanium dioxide multiple interactions ISO RGD:1624096 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP2C38 mRNA, Resveratrol inhibits the reaction [titanium dioxide results in increased expression of CYP2C38 mRNA] CTD PMID:29950665 , PMID:31298478 tofacitinib increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of tofacitinib CTD PMID:31414593 tolbutamide increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of Tolbutamide CTD PMID:18511451 tolbutamide increases hydroxylation ISO RGD:737416 6480464 CYP2C19 protein results in increased hydroxylation of Tolbutamide CTD PMID:30500380 tolbutamide multiple interactions ISO RGD:737416 6480464 [CYP2C19 protein results in increased hydroxylation of Tolbutamide] which results in increased chemical synthesis of 4'-hydroxytolbutamide CTD PMID:30500380 toluene increases oxidation EXP 6480464 CYP2C6V1 protein results in increased oxidation of Toluene CTD PMID:1994898 trans-1,2-dichloroethene decreases activity EXP 6480464 1, 2-dichloroethylene results in decreased activity of CYP2C6V1 protein CTD PMID:9671540 trans-chalcone increases hydroxylation EXP 6480464 CYP2C6V1 protein results in increased hydroxylation of Chalcone CTD PMID:15863696 trans-cinnamic acid decreases activity ISO RGD:737416 6480464 cinnamic acid analog results in decreased activity of CYP2C19 protein CTD PMID:15072549 tranylcypromine decreases activity ISO RGD:737416 6480464 Tranylcypromine results in decreased activity of CYP2C19 protein CTD PMID:15306208 more ... tranylcypromine multiple interactions ISO RGD:737416 6480464 Tranylcypromine affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] more ... CTD PMID:12569440 more ... trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of CYP2C6V1 mRNA CTD PMID:33387578 triclosan increases expression ISO RGD:737416 6480464 Triclosan results in increased expression of CYP2C19 mRNA, Triclosan results in increased expression of CYP2C22 mRNA CTD PMID:29849464 triflumuron increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of triflumuron CTD PMID:31082524 triflumuron multiple interactions ISO RGD:737416 6480464 Sulfaphenazole inhibits the reaction [CYP2C19 protein results in increased metabolism of triflumuron] CTD PMID:31082524 troglitazone increases response to substance ISO RGD:737416 6480464 CYP2C19 gene polymorphism results in increased susceptibility to troglitazone CTD PMID:12963435 troglitazone increases expression ISO RGD:737416 6480464 troglitazone results in increased expression of CYP2C19 mRNA CTD PMID:25572481 troglitazone multiple interactions ISO RGD:737416 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to troglitazone CTD PMID:23397584 troglitazone increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of troglitazone CTD PMID:19356091 troglitazone decreases activity ISO RGD:737416 6480464 Troglitazone results in decreased activity of CYP2C19 protein CTD PMID:12642470 , PMID:33438235 tryptamines multiple interactions ISO RGD:737416 6480464 [Tryptamines analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole CTD PMID:26599973 tryptamines decreases activity ISO RGD:737416 6480464 Tryptamines analog results in decreased activity of CYP2C19 protein CTD PMID:26599973 ursodeoxycholic acid multiple interactions EXP 6480464 Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of CYP2C6V1 protein] CTD PMID:10453939 ursolic acid decreases activity ISO RGD:737416 6480464 ursolic acid results in decreased activity of CYP2C19 protein CTD PMID:15043991 ursolic acid multiple interactions ISO RGD:737416 6480464 ursolic acid inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin] CTD PMID:15043991 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of CYP2C6V1 mRNA CTD PMID:24136188 valproic acid decreases methylation ISO RGD:737416 6480464 Valproic Acid results in decreased methylation of CYP2C19 gene CTD PMID:29154799 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of CYP2C6V1 mRNA CTD PMID:35594946 valproic acid increases response to substance ISO RGD:737416 6480464 CYP2C19 protein results in increased susceptibility to Valproic Acid CTD PMID:28762043 valproic acid affects expression ISO RGD:1624096 6480464 Valproic Acid affects the expression of CYP2C38 mRNA CTD PMID:17963808 valproic acid increases expression ISO RGD:737416 6480464 Valproic Acid results in increased expression of CYP2C19 mRNA CTD PMID:25084468 valproic acid decreases expression ISO RGD:737416 6480464 Valproic Acid results in decreased expression of CYP2C19 mRNA CTD PMID:29154799 vanoxerine dihydrochloride multiple interactions ISO RGD:737416 6480464 [Mephenytoin results in decreased activity of CYP2C19 protein] which results in decreased degradation of vanoxerine CTD PMID:11502731 veliparib increases metabolic processing ISO RGD:737416 6480464 CYP2C19 protein results in increased metabolism of veliparib CTD PMID:21436403 venlafaxine hydrochloride affects methylation ISO RGD:737416 6480464 CYP2C19 gene polymorphism affects the methylation of Venlafaxine Hydrochloride CTD PMID:10877013 venlafaxine hydrochloride decreases methylation ISO RGD:737416 6480464 CYP2C19 protein results in decreased methylation of Venlafaxine Hydrochloride CTD PMID:10877013 voriconazole affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Voriconazole CTD PMID:15914520 voriconazole decreases activity ISO RGD:737416 6480464 Voriconazole results in decreased activity of CYP2C19 protein CTD PMID:15328084 , PMID:15914520 warfarin affects metabolic processing ISO RGD:737416 6480464 CYP2C19 protein affects the metabolism of Warfarin CTD PMID:18520598 warfarin multiple interactions ISO RGD:737416 6480464 CYP2C19 gene polymorphism affects the metabolism of and affects the susceptibility to Warfarin, Omeprazole affects the reaction [CYP2C19 protein affects the metabolism of Warfarin] CTD PMID:18520598 , PMID:25652102 warfarin affects response to substance ISO RGD:737416 6480464 CYP2C19 gene polymorphism affects the susceptibility to Warfarin more ... CTD PMID:19752777 , PMID:27356304 zafirlukast decreases activity ISO RGD:737416 6480464 zafirlukast results in decreased activity of CYP2C19 protein CTD PMID:15370959 zafirlukast multiple interactions ISO RGD:737416 6480464 zafirlukast inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin] CTD PMID:15370959 zerumbone increases expression ISO RGD:737416 6480464 zerumbone results in increased expression of CYP2C19 mRNA CTD PMID:36122806
