Sorbs1 (sorbin and SH3 domain containing 1) - Rat Genome Database

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Gene: Sorbs1 (sorbin and SH3 domain containing 1) Rattus norvegicus
Analyze
Symbol: Sorbs1
Name: sorbin and SH3 domain containing 1
RGD ID: 1586598
Description: Enables insulin receptor binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including response to L-glutamate; response to activity; and response to insulin. Part of insulin receptor complex. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human SORBS1 (sorbin and SH3 domain containing 1); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; insulin signaling pathway; Rho/Rac/Cdc42 mediated signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CAP; Cbl associated protein; LOC686098; ponsin; SH3P12; similar to sorbin and SH3 domain containing 1 isoform 3; sorbin and SH3 domain-containing protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81249,057,324 - 249,279,703 (-)NCBIGRCr8
mRatBN7.21239,107,882 - 239,330,276 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1239,108,777 - 239,330,169 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01259,373,921 - 259,502,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1259,376,933 - 259,484,569 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01266,817,755 - 267,037,940 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41245,419,532 - 245,527,846 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1234,954,631 - 235,082,791 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-tribromophenol  (ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
amphotericin B  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
caffeine  (ISO)
cantharidin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (EXP,ISO)
clothianidin  (ISO)
copper(II) chloride  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glafenine  (EXP)
indometacin  (ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
lead(0)  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
methamphetamine  (ISO)
methyl methanesulfonate  (ISO)
methylseleninic acid  (ISO)
mitomycin C  (ISO)
mitoxantrone  (ISO)
Muraglitazar  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
ozone  (EXP,ISO)
p-toluidine  (EXP)
paracetamol  (EXP)
paraquat  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
progesterone  (ISO)
propanal  (ISO)
propiconazole  (ISO)
quercetin  (EXP,ISO)
quercitrin  (ISO)
rac-lactic acid  (ISO)
rifampicin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
testosterone enanthate  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (ISO)
troglitazone  (EXP,ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
adherens junction  (ISO,ISS)
cell-substrate junction  (IEA,ISO,ISS)
centrosome  (IEA,ISO)
cytoplasm  (IEA)
cytoskeleton  (ISO)
cytosol  (ISO)
flotillin complex  (ISO)
focal adhesion  (IEA,ISO)
insulin receptor complex  (IDA)
membrane  (ISO)
membrane raft  (ISO,ISS)
nuclear matrix  (ISO)
nucleus  (IEA,ISO,ISS)
plasma membrane  (IEA,ISO)
stress fiber  (ISO,ISS)
synapse  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Exercise training increases components of the c-Cbl-associated protein/c-Cbl signaling cascade in muscle of obese Zucker rats. Bernard JR, etal., Metabolism. 2008 Jun;57(6):858-66. doi: 10.1016/j.metabol.2008.01.035.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance. Lesniewski LA, etal., Nat Med. 2007 Apr;13(4):455-62. Epub 2007 Mar 11.
4. Molecular scanning of the human sorbin and SH3-domain-containing-1 (SORBS1) gene: positive association of the T228A polymorphism with obesity and type 2 diabetes. Lin WH, etal., Hum Mol Genet. 2001 Aug 15;10(17):1753-60.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. Selective modulation of the CAP/Cbl pathway in the adipose tissue of high fat diet treated rats. Prada PO, etal., FEBS Lett. 2006 Sep 4;580(20):4889-94. Epub 2006 Aug 10.
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Activation of atypical protein kinase Czeta toward TC10 is regulated by high-fat diet and aerobic exercise in skeletal muscle. Saito M, etal., Metabolism. 2008 Sep;57(9):1173-80. doi: 10.1016/j.metabol.2008.03.023.
12. Rho GTPases in insulin-stimulated glucose uptake. Satoh T Small GTPases. 2014;5:e28102. doi: 10.4161/sgtp.28102. Epub 2014 Mar 10.
13. Regulation of Cbl-associated protein/Cbl pathway in muscle and adipose tissues of two animal models of insulin resistance. Thirone AC, etal., Endocrinology. 2004 Jan;145(1):281-93. Epub 2003 Oct 2.
Additional References at PubMed
PMID:9447983   PMID:9461600   PMID:10085297   PMID:11001060   PMID:11371513   PMID:11374898   PMID:12079283   PMID:15777793   PMID:19116150   PMID:26527617  


Genomics

Comparative Map Data
Sorbs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81249,057,324 - 249,279,703 (-)NCBIGRCr8
mRatBN7.21239,107,882 - 239,330,276 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1239,108,777 - 239,330,169 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01259,373,921 - 259,502,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1259,376,933 - 259,484,569 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01266,817,755 - 267,037,940 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41245,419,532 - 245,527,846 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1234,954,631 - 235,082,791 (-)NCBICelera
Cytogenetic Map1q54NCBI
SORBS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381095,311,773 - 95,561,371 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1095,311,771 - 95,561,414 (-)EnsemblGRCh38hg38GRCh38
GRCh371097,071,530 - 97,321,128 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361097,061,520 - 97,311,161 (-)NCBINCBI36Build 36hg18NCBI36
Build 341097,061,520 - 97,311,125NCBI
Celera1090,812,720 - 91,062,378 (-)NCBICelera
Cytogenetic Map10q24.1NCBI
HuRef1090,698,450 - 90,948,671 (-)NCBIHuRef
CHM1_11097,353,333 - 97,602,949 (-)NCBICHM1_1
T2T-CHM13v2.01096,190,944 - 96,440,561 (-)NCBIT2T-CHM13v2.0
Sorbs1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391940,280,484 - 40,502,399 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1940,283,197 - 40,502,223 (-)EnsemblGRCm39 Ensembl
GRCm381940,292,040 - 40,513,955 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1940,294,753 - 40,513,779 (-)EnsemblGRCm38mm10GRCm38
MGSCv371940,366,530 - 40,588,302 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361940,345,351 - 40,567,123 (-)NCBIMGSCv36mm8
Celera1941,096,960 - 41,318,133 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1934.25NCBI
Sorbs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555071,622,567 - 1,738,423 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555071,622,567 - 1,849,047 (-)NCBIChiLan1.0ChiLan1.0
SORBS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28107,215,332 - 107,465,417 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110107,220,650 - 107,470,735 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01091,922,292 - 92,172,339 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11095,429,538 - 95,608,795 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1095,432,824 - 95,559,022 (-)Ensemblpanpan1.1panPan2
SORBS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1288,834,530 - 9,063,739 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl288,837,338 - 9,063,777 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha289,010,719 - 9,239,721 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0289,096,613 - 9,325,738 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl289,096,619 - 9,325,647 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1288,813,634 - 9,042,380 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0288,872,692 - 9,101,483 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0289,016,118 - 9,245,183 (-)NCBIUU_Cfam_GSD_1.0
Sorbs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721337,795,716 - 38,027,177 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366363,948,733 - 4,066,293 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366363,834,887 - 4,066,293 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SORBS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14106,895,765 - 107,137,561 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114106,895,764 - 107,137,469 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214116,528,972 - 116,771,224 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SORBS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1988,475,783 - 88,729,912 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl988,472,946 - 88,729,851 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604849,347,919 - 49,597,486 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sorbs1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247376,647,651 - 6,786,335 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247376,646,837 - 6,875,408 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sorbs1
1394 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:210
Count of miRNA genes:74
Interacting mature miRNAs:76
Transcripts:ENSRNOT00000021114, ENSRNOT00000021226, ENSRNOT00000021229, ENSRNOT00000021289, ENSRNOT00000021347
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316896Gluco57Glucose level QTL 577.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228985440245907899Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1197814409242814409Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233190394258625266Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1221264111259647894Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
631836Stl31Serum triglyceride level QTL 314.640.00000487blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1237147813260522016Rat
631837Niddm35Non-insulin dependent diabetes mellitus QTL 350.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1238699859259647894Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1201554356246554356Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1228581588259647894Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
1357399Bw45Body weight QTL 453.05body mass (VT:0001259)body mass index (BMI) (CMO:0000105)1206329708251329708Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
1358292Cm37Cardiac mass QTL 376.20.00000081heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1232156370259647894Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1218748008257976495Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1203995416244113296Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1218753689245907899Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1218753816256448513Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1224054293243747962Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
2292216Bw80Body weight QTL 803.230.0019body mass (VT:0001259)body weight (CMO:0000012)1213533809243914901Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1233948574260522016Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1210702053240947965Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1197814409242814409Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1213843987258843987Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1197670404242670404Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1201554356246554356Rat
1357404Bw42Body weight QTL 424.490.0001body mass (VT:0001259)body weight (CMO:0000012)1206329708251329708Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1224054293243747962Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1206081677251081677Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
10059587Bw173Body weight QTL 1733.230.025body mass (VT:0001259)body weight (CMO:0000012)1202069611247069611Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1201554356246554356Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1213707201252085212Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 42 19 8 3 8 6 7 72 29 14 11 6
Low 1 1 38 33 16 33 2 4 2 6 27 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001421361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC109039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC128172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000021114   ⟹   ENSRNOP00000021114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1239,108,777 - 239,330,169 (-)Ensembl
Rnor_6.0 Ensembl1259,376,933 - 259,484,569 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000021226   ⟹   ENSRNOP00000021225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1239,108,777 - 239,330,169 (-)Ensembl
Rnor_6.0 Ensembl1259,376,933 - 259,484,569 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000021229   ⟹   ENSRNOP00000021229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1239,108,777 - 239,235,731 (-)Ensembl
Rnor_6.0 Ensembl1259,376,933 - 259,484,569 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000021289   ⟹   ENSRNOP00000021289
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1239,108,777 - 239,330,169 (-)Ensembl
Rnor_6.0 Ensembl1259,376,933 - 259,484,569 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000021347   ⟹   ENSRNOP00000021347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1239,108,777 - 239,330,169 (-)Ensembl
Rnor_6.0 Ensembl1259,376,933 - 259,484,569 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099566   ⟹   ENSRNOP00000090228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1239,108,777 - 239,203,969 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100551   ⟹   ENSRNOP00000097497
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1239,108,777 - 239,330,169 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118133   ⟹   ENSRNOP00000093266
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1239,108,777 - 239,330,169 (-)Ensembl
RefSeq Acc Id: NM_001421361   ⟹   NP_001408290
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,279,608 (-)NCBI
mRatBN7.21239,107,882 - 239,330,180 (-)NCBI
RefSeq Acc Id: XM_039095037   ⟹   XP_038950965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,875 (-)NCBI
mRatBN7.21239,107,882 - 239,236,126 (-)NCBI
RefSeq Acc Id: XM_039095140   ⟹   XP_038951068
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,863 (-)NCBI
mRatBN7.21239,107,882 - 239,236,017 (-)NCBI
RefSeq Acc Id: XM_039095147   ⟹   XP_038951075
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,862 (-)NCBI
mRatBN7.21239,107,882 - 239,236,013 (-)NCBI
RefSeq Acc Id: XM_039095154   ⟹   XP_038951082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,861 (-)NCBI
mRatBN7.21239,107,882 - 239,236,008 (-)NCBI
RefSeq Acc Id: XM_039095156   ⟹   XP_038951084
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,862 (-)NCBI
mRatBN7.21239,107,882 - 239,236,012 (-)NCBI
RefSeq Acc Id: XM_039095158   ⟹   XP_038951086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,862 (-)NCBI
mRatBN7.21239,107,882 - 239,236,013 (-)NCBI
RefSeq Acc Id: XM_039095161   ⟹   XP_038951089
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,861 (-)NCBI
mRatBN7.21239,107,882 - 239,236,008 (-)NCBI
RefSeq Acc Id: XM_039095169   ⟹   XP_038951097
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,861 (-)NCBI
mRatBN7.21239,107,882 - 239,236,008 (-)NCBI
RefSeq Acc Id: XM_039095212   ⟹   XP_038951140
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,863 (-)NCBI
mRatBN7.21239,107,882 - 239,236,014 (-)NCBI
RefSeq Acc Id: XM_039095216   ⟹   XP_038951144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,861 (-)NCBI
mRatBN7.21239,107,882 - 239,236,005 (-)NCBI
RefSeq Acc Id: XM_039095220   ⟹   XP_038951148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,853 (-)NCBI
mRatBN7.21239,107,882 - 239,235,977 (-)NCBI
RefSeq Acc Id: XM_039095225   ⟹   XP_038951153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,863 (-)NCBI
mRatBN7.21239,107,882 - 239,236,017 (-)NCBI
RefSeq Acc Id: XM_039095228   ⟹   XP_038951156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,861 (-)NCBI
mRatBN7.21239,107,882 - 239,236,008 (-)NCBI
RefSeq Acc Id: XM_063273944   ⟹   XP_063130014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,279,702 (-)NCBI
RefSeq Acc Id: XM_063273951   ⟹   XP_063130021
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,279,167 (-)NCBI
RefSeq Acc Id: XM_063273954   ⟹   XP_063130024
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,279,703 (-)NCBI
RefSeq Acc Id: XM_063273958   ⟹   XP_063130028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,279,703 (-)NCBI
RefSeq Acc Id: XM_063273962   ⟹   XP_063130032
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,279,703 (-)NCBI
RefSeq Acc Id: XM_063273964   ⟹   XP_063130034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,279,703 (-)NCBI
RefSeq Acc Id: XM_063273968   ⟹   XP_063130038
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,279,703 (-)NCBI
RefSeq Acc Id: XM_063273977   ⟹   XP_063130047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,279,703 (-)NCBI
RefSeq Acc Id: XM_063273987   ⟹   XP_063130057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,279,703 (-)NCBI
RefSeq Acc Id: XM_063273991   ⟹   XP_063130061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,165,087 (-)NCBI
RefSeq Acc Id: XM_063273992   ⟹   XP_063130062
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,873 (-)NCBI
RefSeq Acc Id: XM_063273994   ⟹   XP_063130064
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,872 (-)NCBI
RefSeq Acc Id: XM_063273996   ⟹   XP_063130066
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,873 (-)NCBI
RefSeq Acc Id: XM_063273997   ⟹   XP_063130067
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,873 (-)NCBI
RefSeq Acc Id: XM_063274002   ⟹   XP_063130072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,873 (-)NCBI
RefSeq Acc Id: XM_063274011   ⟹   XP_063130081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,872 (-)NCBI
RefSeq Acc Id: XM_063274018   ⟹   XP_063130088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,872 (-)NCBI
RefSeq Acc Id: XM_063274026   ⟹   XP_063130096
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,872 (-)NCBI
RefSeq Acc Id: XM_063274030   ⟹   XP_063130100
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,871 (-)NCBI
RefSeq Acc Id: XM_063274034   ⟹   XP_063130104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,871 (-)NCBI
RefSeq Acc Id: XM_063274037   ⟹   XP_063130107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,870 (-)NCBI
RefSeq Acc Id: XM_063274047   ⟹   XP_063130117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,872 (-)NCBI
RefSeq Acc Id: XM_063274053   ⟹   XP_063130123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,871 (-)NCBI
RefSeq Acc Id: XM_063274059   ⟹   XP_063130129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,870 (-)NCBI
RefSeq Acc Id: XM_063274063   ⟹   XP_063130133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,864 (-)NCBI
RefSeq Acc Id: XM_063274069   ⟹   XP_063130139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,864 (-)NCBI
RefSeq Acc Id: XM_063274072   ⟹   XP_063130142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,865 (-)NCBI
RefSeq Acc Id: XM_063274083   ⟹   XP_063130153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,863 (-)NCBI
RefSeq Acc Id: XM_063274089   ⟹   XP_063130159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,863 (-)NCBI
RefSeq Acc Id: XM_063274095   ⟹   XP_063130165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,864 (-)NCBI
RefSeq Acc Id: XM_063274100   ⟹   XP_063130170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,863 (-)NCBI
RefSeq Acc Id: XM_063274112   ⟹   XP_063130182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,864 (-)NCBI
RefSeq Acc Id: XM_063274118   ⟹   XP_063130188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,862 (-)NCBI
RefSeq Acc Id: XM_063274119   ⟹   XP_063130189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,863 (-)NCBI
RefSeq Acc Id: XM_063274125   ⟹   XP_063130195
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,862 (-)NCBI
RefSeq Acc Id: XM_063274132   ⟹   XP_063130202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,857 (-)NCBI
RefSeq Acc Id: XM_063274133   ⟹   XP_063130203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81249,057,324 - 249,218,856 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001408290 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950965 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951068 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951075 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951082 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951084 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951086 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951089 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951097 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951140 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951144 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951148 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951153 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951156 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130014 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130021 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130024 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130028 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130032 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130034 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130038 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130047 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130057 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130061 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130062 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130064 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130066 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130067 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130072 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130081 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130088 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130096 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130100 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130104 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130107 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130117 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130123 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130129 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130133 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130139 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130142 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130153 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130159 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130165 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130170 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130182 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130188 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130189 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130195 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130202 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130203 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94183 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021114
  ENSRNOP00000021114.6
  ENSRNOP00000021225
  ENSRNOP00000021225.5
  ENSRNOP00000021229.6
  ENSRNOP00000021289.6
  ENSRNOP00000021347.4
  ENSRNOP00000090228.1
  ENSRNOP00000093266.1
  ENSRNOP00000097497
  ENSRNOP00000097497.1
GenBank Protein P84109 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: ENSRNOP00000021114   ⟸   ENSRNOT00000021114
RefSeq Acc Id: ENSRNOP00000021229   ⟸   ENSRNOT00000021229
RefSeq Acc Id: ENSRNOP00000021225   ⟸   ENSRNOT00000021226
RefSeq Acc Id: ENSRNOP00000021347   ⟸   ENSRNOT00000021347
RefSeq Acc Id: ENSRNOP00000021289   ⟸   ENSRNOT00000021289
RefSeq Acc Id: XP_038950965   ⟸   XM_039095037
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038951153   ⟸   XM_039095225
- Peptide Label: isoform X43
- UniProtKB: F1M866 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951068   ⟸   XM_039095140
- Peptide Label: isoform X21
- UniProtKB: F1M866 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951140   ⟸   XM_039095212
- Peptide Label: isoform X37
- UniProtKB: A0A8I6ASS7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951086   ⟸   XM_039095158
- Peptide Label: isoform X30
- UniProtKB: F1M866 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951075   ⟸   XM_039095147
- Peptide Label: isoform X24
- UniProtKB: F1M866 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951084   ⟸   XM_039095156
- Peptide Label: isoform X28
- UniProtKB: F1M866 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951156   ⟸   XM_039095228
- Peptide Label: isoform X44
- UniProtKB: F1M866 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951089   ⟸   XM_039095161
- Peptide Label: isoform X32
- UniProtKB: F1M866 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951082   ⟸   XM_039095154
- Peptide Label: isoform X26
- UniProtKB: F1M866 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951097   ⟸   XM_039095169
- Peptide Label: isoform X33
- UniProtKB: F1M866 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951144   ⟸   XM_039095216
- Peptide Label: isoform X39
- UniProtKB: A0A8I6ASS7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951148   ⟸   XM_039095220
- Peptide Label: isoform X41
RefSeq Acc Id: ENSRNOP00000090228   ⟸   ENSRNOT00000099566
RefSeq Acc Id: ENSRNOP00000093266   ⟸   ENSRNOT00000118133
RefSeq Acc Id: ENSRNOP00000097497   ⟸   ENSRNOT00000100551
RefSeq Acc Id: NP_001408290   ⟸   NM_001421361
RefSeq Acc Id: XP_063130057   ⟸   XM_063273987
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063130028   ⟸   XM_063273958
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063130038   ⟸   XM_063273968
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063130032   ⟸   XM_063273962
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063130047   ⟸   XM_063273977
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063130034   ⟸   XM_063273964
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063130024   ⟸   XM_063273954
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063130014   ⟸   XM_063273944
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063130021   ⟸   XM_063273951
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063130067   ⟸   XM_063273997
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063130066   ⟸   XM_063273996
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063130072   ⟸   XM_063274002
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063130062   ⟸   XM_063273992
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063130088   ⟸   XM_063274018
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063130064   ⟸   XM_063273994
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063130117   ⟸   XM_063274047
- Peptide Label: isoform X17
RefSeq Acc Id: XP_063130096   ⟸   XM_063274026
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063130081   ⟸   XM_063274011
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063130123   ⟸   XM_063274053
- Peptide Label: isoform X18
RefSeq Acc Id: XP_063130100   ⟸   XM_063274030
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063130104   ⟸   XM_063274034
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063130107   ⟸   XM_063274037
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063130129   ⟸   XM_063274059
- Peptide Label: isoform X19
RefSeq Acc Id: XP_063130142   ⟸   XM_063274072
- Peptide Label: isoform X23
RefSeq Acc Id: XP_063130139   ⟸   XM_063274069
- Peptide Label: isoform X22
RefSeq Acc Id: XP_063130182   ⟸   XM_063274112
- Peptide Label: isoform X34
RefSeq Acc Id: XP_063130165   ⟸   XM_063274095
- Peptide Label: isoform X29
RefSeq Acc Id: XP_063130133   ⟸   XM_063274063
- Peptide Label: isoform X20
RefSeq Acc Id: XP_063130189   ⟸   XM_063274119
- Peptide Label: isoform X36
RefSeq Acc Id: XP_063130170   ⟸   XM_063274100
- Peptide Label: isoform X31
RefSeq Acc Id: XP_063130159   ⟸   XM_063274089
- Peptide Label: isoform X27
RefSeq Acc Id: XP_063130153   ⟸   XM_063274083
- Peptide Label: isoform X25
RefSeq Acc Id: XP_063130195   ⟸   XM_063274125
- Peptide Label: isoform X38
RefSeq Acc Id: XP_063130188   ⟸   XM_063274118
- Peptide Label: isoform X35
RefSeq Acc Id: XP_063130202   ⟸   XM_063274132
- Peptide Label: isoform X40
RefSeq Acc Id: XP_063130203   ⟸   XM_063274133
- Peptide Label: isoform X42
RefSeq Acc Id: XP_063130061   ⟸   XM_063273991
- Peptide Label: isoform X5
Protein Domains
SH3   SoHo

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P84109-F1-model_v2 AlphaFold P84109 1-35 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586598 AgrOrtholog
BioCyc Gene G2FUF-55719 BioCyc
Ensembl Genes ENSRNOG00000015658 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021114.9 UniProtKB/TrEMBL
  ENSRNOT00000021226.6 UniProtKB/TrEMBL
  ENSRNOT00000021229.9 UniProtKB/TrEMBL
  ENSRNOT00000021289.9 UniProtKB/TrEMBL
  ENSRNOT00000021347.8 UniProtKB/TrEMBL
  ENSRNOT00000099566.1 UniProtKB/TrEMBL
  ENSRNOT00000100551.1 UniProtKB/TrEMBL
  ENSRNOT00000118133.1 UniProtKB/TrEMBL
Gene3D-CATH SH3 Domains UniProtKB/TrEMBL
InterPro SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  Sorb UniProtKB/TrEMBL
  SORBS1_SH3 UniProtKB/TrEMBL
  SORBS1_SH3_1 UniProtKB/TrEMBL
  SORBS1_SH3_2 UniProtKB/TrEMBL
NCBI Gene 686098 ENTREZGENE
PANTHER SH3 DOMAIN-CONTAINING UniProtKB/TrEMBL
  SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam SH3_1 UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
  Sorb UniProtKB/TrEMBL
PhenoGen Sorbs1 PhenoGen
PRINTS P67PHOX UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/TrEMBL
  SOHO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015658 RatGTEx
SMART SH3 UniProtKB/TrEMBL
  Sorb UniProtKB/TrEMBL
Superfamily-SCOP SH3 UniProtKB/TrEMBL
UniProt A0A8I6ABE1_RAT UniProtKB/TrEMBL
  A0A8I6AFH7_RAT UniProtKB/TrEMBL
  A0A8I6ASS7 ENTREZGENE, UniProtKB/TrEMBL
  F1M820_RAT UniProtKB/TrEMBL
  F1M840_RAT UniProtKB/TrEMBL
  F1M865_RAT UniProtKB/TrEMBL
  F1M866 ENTREZGENE, UniProtKB/TrEMBL
  F1M8Z8_RAT UniProtKB/TrEMBL
  P84109 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-07-08 Sorbs1  sorbin and SH3 domain containing 1   LOC678826  similar to sorbin and SH3 domain containing 1 isoform 3  Data merged from RGD:1595590 1643240 APPROVED
2008-04-30 Sorbs1  sorbin and SH3 domain containing 1   Sorbs1_predicted  sorbin and SH3 domain containing 1 (predicted)  'predicted' is removed 2292626 APPROVED
2007-10-11 Sorbs1_predicted  sorbin and SH3 domain containing 1 (predicted)  LOC686098  similar to sorbin and SH3 domain containing 1 isoform 3  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 PENDING
2006-11-20 LOC678826  similar to sorbin and SH3 domain containing 1 isoform 3      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC686098  similar to sorbin and SH3 domain containing 1 isoform 3      Symbol and Name status set to provisional 70820 PROVISIONAL