Elovl2 (ELOVL fatty acid elongase 2) - Rat Genome Database

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Gene: Elovl2 (ELOVL fatty acid elongase 2) Rattus norvegicus
Analyze
Symbol: Elovl2
Name: ELOVL fatty acid elongase 2
RGD ID: 1308605
Description: Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to act upstream of or within very long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human ELOVL2 (ELOVL fatty acid elongase 2); PARTICIPATES IN unsaturated fatty acid biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 3-keto acyl-CoA synthase Elovl2; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2; elongation of very long chain fatty acids protein 2; elongation of very long chain fatty acids-like 2; ELOVL FA elongase 2; LOC361231; very long chain 3-ketoacyl-CoA synthase 2; very long chain 3-oxoacyl-CoA synthase 2; very-long-chain 3-oxoacyl-CoA synthase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21723,544,520 - 23,584,855 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1723,544,568 - 23,584,848 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1723,413,950 - 23,454,031 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01725,017,637 - 25,057,488 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01723,354,897 - 23,394,980 (+)NCBIRnor_WKY
Rnor_6.01721,382,461 - 21,422,413 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1721,382,455 - 21,422,407 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01723,366,123 - 23,405,734 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41729,492,349 - 29,532,622 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1723,217,076 - 23,256,130 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
aristolochic acid  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
butyric acid  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fipronil  (EXP)
fulvestrant  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
methapyrilene  (EXP)
methylmercury chloride  (ISO)
methylparaben  (ISO)
nefazodone  (EXP)
nickel sulfate  (ISO)
nitrofen  (EXP)
obeticholic acid  (ISO)
p-toluidine  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenformin  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thapsigargin  (ISO)
trichostatin A  (ISO)
Triptolide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10970790   PMID:11567032   PMID:12371743   PMID:14636670   PMID:20937905   PMID:21106902   PMID:22871113   PMID:23873268  


Genomics

Comparative Map Data
Elovl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21723,544,520 - 23,584,855 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1723,544,568 - 23,584,848 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1723,413,950 - 23,454,031 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01725,017,637 - 25,057,488 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01723,354,897 - 23,394,980 (+)NCBIRnor_WKY
Rnor_6.01721,382,461 - 21,422,413 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1721,382,455 - 21,422,407 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01723,366,123 - 23,405,734 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41729,492,349 - 29,532,622 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1723,217,076 - 23,256,130 (+)NCBICelera
Cytogenetic Map17p14NCBI
ELOVL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38610,980,759 - 11,044,305 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl610,980,759 - 11,044,305 (-)EnsemblGRCh38hg38GRCh38
GRCh37610,980,992 - 11,044,538 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36611,088,978 - 11,152,610 (-)NCBINCBI36Build 36hg18NCBI36
Build 34611,088,980 - 11,152,563NCBI
Celera612,209,434 - 12,273,087 (-)NCBICelera
Cytogenetic Map6p24.2NCBI
HuRef610,912,756 - 10,942,802 (-)NCBIHuRef
CHM1_1610,983,093 - 11,046,725 (-)NCBICHM1_1
T2T-CHM13v2.0610,848,429 - 10,911,922 (-)NCBIT2T-CHM13v2.0
Elovl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391341,335,858 - 41,373,879 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1341,335,857 - 41,373,881 (-)EnsemblGRCm39 Ensembl
GRCm381341,182,382 - 41,220,403 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1341,182,381 - 41,220,405 (-)EnsemblGRCm38mm10GRCm38
MGSCv371341,277,751 - 41,315,772 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361341,193,473 - 41,231,367 (-)NCBIMGSCv36mm8
Celera1342,264,179 - 42,302,191 (-)NCBICelera
Cytogenetic Map13A3.3NCBI
Elovl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554653,413,923 - 3,430,714 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554653,413,923 - 3,433,558 (+)NCBIChiLan1.0ChiLan1.0
ELOVL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1611,097,903 - 11,129,287 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl611,097,903 - 11,127,911 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0610,820,972 - 10,884,609 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ELOVL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13510,690,534 - 10,720,374 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3510,693,113 - 10,720,348 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3510,639,692 - 10,702,198 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03510,792,834 - 10,855,319 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3510,792,716 - 10,855,254 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13510,623,411 - 10,685,944 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03510,671,754 - 10,734,250 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03511,993,503 - 12,055,868 (-)NCBIUU_Cfam_GSD_1.0
Elovl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494613,727,047 - 13,749,790 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365341,996,111 - 2,016,184 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELOVL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl77,651,601 - 7,774,018 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.177,651,707 - 7,732,353 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.277,976,965 - 8,025,779 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ELOVL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11761,099,153 - 61,159,213 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1761,099,255 - 61,159,207 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604411,017,014 - 11,077,132 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elovl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475614,978,195 - 14,992,938 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475614,934,048 - 14,995,801 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH143974  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21723,584,557 - 23,584,666 (+)MAPPERmRatBN7.2
Rnor_6.01721,422,120 - 21,422,228NCBIRnor6.0
Rnor_5.01723,405,441 - 23,405,549UniSTSRnor5.0
RGSC_v3.41729,532,332 - 29,532,440UniSTSRGSC3.4
Celera1723,255,840 - 23,255,948UniSTS
Cytogenetic Map17p12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920136523653323Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920136523653323Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:410
Count of miRNA genes:230
Interacting mature miRNAs:294
Transcripts:ENSRNOT00000019756
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 41 41 41 74 29 26
Low 2 18 8 1 3 3 6 11 3 3
Below cutoff 1 23 8 17 5 6 4 8 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000019756   ⟹   ENSRNOP00000019756
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1723,544,831 - 23,584,848 (+)Ensembl
Rnor_6.0 Ensembl1721,382,455 - 21,422,407 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000107946   ⟹   ENSRNOP00000092117
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1723,552,721 - 23,584,848 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112684   ⟹   ENSRNOP00000097427
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1723,566,893 - 23,584,848 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115567   ⟹   ENSRNOP00000097102
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1723,544,568 - 23,584,848 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116778   ⟹   ENSRNOP00000091242
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1723,571,155 - 23,584,848 (+)Ensembl
RefSeq Acc Id: NM_001109118   ⟹   NP_001102588
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21723,544,831 - 23,584,848 (+)NCBI
Rnor_6.01721,382,461 - 21,422,410 (+)NCBI
Rnor_5.01723,366,123 - 23,405,734 (+)NCBI
RGSC_v3.41729,492,349 - 29,532,622 (+)RGD
Celera1723,217,076 - 23,256,130 (+)RGD
Sequence:
RefSeq Acc Id: XM_006253779   ⟹   XP_006253841
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21723,544,667 - 23,584,855 (+)NCBI
Rnor_6.01721,382,583 - 21,422,413 (+)NCBI
Rnor_5.01723,366,123 - 23,405,734 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096006   ⟹   XP_038951934
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21723,544,520 - 23,584,855 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001102588 (Get FASTA)   NCBI Sequence Viewer  
  XP_006253841 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951934 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D4A612 (Get FASTA)   NCBI Sequence Viewer  
  EDL98219 (Get FASTA)   NCBI Sequence Viewer  
  EDL98220 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001102588   ⟸   NM_001109118
- UniProtKB: D4A612 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006253841   ⟸   XM_006253779
- Peptide Label: isoform X2
- UniProtKB: D4A612 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000019756   ⟸   ENSRNOT00000019756
RefSeq Acc Id: XP_038951934   ⟸   XM_039096006
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000091242   ⟸   ENSRNOT00000116778
RefSeq Acc Id: ENSRNOP00000097102   ⟸   ENSRNOT00000115567
RefSeq Acc Id: ENSRNOP00000092117   ⟸   ENSRNOT00000107946
RefSeq Acc Id: ENSRNOP00000097427   ⟸   ENSRNOT00000112684

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A612-F1-model_v2 AlphaFold D4A612 1-279 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308605 AgrOrtholog
BioCyc Gene G2FUF-9733 BioCyc
Ensembl Genes ENSRNOG00000014702 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000019756 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000091242.1 UniProtKB/TrEMBL
  ENSRNOP00000092117.1 UniProtKB/TrEMBL
  ENSRNOP00000097102 ENTREZGENE
  ENSRNOP00000097102.1 UniProtKB/TrEMBL
  ENSRNOP00000097427.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019756 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000107946.1 UniProtKB/TrEMBL
  ENSRNOT00000112684.1 UniProtKB/TrEMBL
  ENSRNOT00000115567 ENTREZGENE
  ENSRNOT00000115567.1 UniProtKB/TrEMBL
  ENSRNOT00000116778.1 UniProtKB/TrEMBL
InterPro ELO_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ELO_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ELOVL2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:498728 UniProtKB/Swiss-Prot
NCBI Gene 498728 ENTREZGENE
PANTHER PTHR11157 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11157:SF16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ELO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Elovl2 PhenoGen
PROSITE ELO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6ADC5_RAT UniProtKB/TrEMBL
  A0A8I6ADF0_RAT UniProtKB/TrEMBL
  A0A8I6ANF1_RAT UniProtKB/TrEMBL
  A0A8I6B5B4_RAT UniProtKB/TrEMBL
  D4A612 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Elovl2  ELOVL fatty acid elongase 2  LOC682492  similar to Elongation of very long chain fatty acids protein 2  Data Merged 1643240 APPROVED
2012-07-16 Elovl2  ELOVL fatty acid elongase 2  Elovl2  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Elovl2  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2   Elovl2_predicted  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-19 LOC682492  similar to Elongation of very long chain fatty acids protein 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Elovl2_predicted  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED