Htatip2 (HIV-1 Tat interactive protein 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Htatip2 (HIV-1 Tat interactive protein 2) Rattus norvegicus
Analyze
Symbol: Htatip2
Name: HIV-1 Tat interactive protein 2
RGD ID: 1309941
Description: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in import into nucleus and regulation of angiogenesis. Predicted to act upstream of or within positive regulation of programmed cell death and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nuclear envelope. Predicted to be active in cytoplasm. Orthologous to human HTATIP2 (HIV-1 Tat interactive protein 2); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: HIV-1 tat interactive protein 2, homolog; HIV-1 tat interactive protein 2, homolog (human); LOC292935; oxidoreductase HTATIP2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81108,609,424 - 108,624,810 (+)NCBIGRCr8
mRatBN7.2199,473,411 - 99,488,632 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,469,245 - 99,488,629 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1104,828,076 - 104,842,693 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01113,299,999 - 113,314,616 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01106,622,254 - 106,636,873 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01105,094,272 - 105,109,459 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1105,094,411 - 105,109,461 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01106,144,564 - 106,159,708 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,563,187 - 99,577,802 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1199,640,882 - 99,655,918 (+)NCBI
Celera193,673,035 - 93,687,653 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,4-phenylenediamine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrotoluene  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
antimonite  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
cannabidiol  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
chloroacetaldehyde  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
chrysene  (ISO)
cidofovir anhydrous  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dibenzofurans  (ISO)
dichloroacetic acid  (ISO)
diethyl maleate  (ISO)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
etoposide  (ISO)
fenofibrate  (EXP)
finasteride  (EXP)
fipronil  (EXP)
flutamide  (EXP)
formaldehyde  (ISO)
gentamycin  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
hydrogen peroxide  (ISO)
ibuprofen  (EXP)
indole-3-methanol  (EXP)
inulin  (ISO)
irinotecan  (ISO)
ivermectin  (ISO)
levofloxacin  (EXP)
lipopolysaccharide  (ISO)
malathion  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
metformin  (EXP)
methimazole  (EXP)
methylmercury chloride  (ISO)
methylmercury(1+)  (EXP)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
nefazodone  (EXP)
nickel sulfate  (ISO)
nimesulide  (EXP)
p-chloromercuribenzoic acid  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
parathion  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (EXP)
propofol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sevoflurane  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium tungstate  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
topotecan  (ISO)
triadimefon  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP)
trovafloxacin  (EXP)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,ISO)
cytosol  (IEA,ISO)
nuclear envelope  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10698937   PMID:11313954   PMID:12477932   PMID:15282309   PMID:19946888   PMID:25312779   PMID:31904090  


Genomics

Comparative Map Data
Htatip2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81108,609,424 - 108,624,810 (+)NCBIGRCr8
mRatBN7.2199,473,411 - 99,488,632 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,469,245 - 99,488,629 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1104,828,076 - 104,842,693 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01113,299,999 - 113,314,616 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01106,622,254 - 106,636,873 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01105,094,272 - 105,109,459 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1105,094,411 - 105,109,461 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01106,144,564 - 106,159,708 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,563,187 - 99,577,802 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1199,640,882 - 99,655,918 (+)NCBI
Celera193,673,035 - 93,687,653 (+)NCBICelera
Cytogenetic Map1q22NCBI
HTATIP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381120,363,714 - 20,383,782 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1120,363,685 - 20,383,782 (+)EnsemblGRCh38hg38GRCh38
GRCh371120,385,260 - 20,405,328 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361120,341,807 - 20,361,905 (+)NCBINCBI36Build 36hg18NCBI36
Build 341120,341,923 - 20,361,904NCBI
Celera1120,517,827 - 20,537,915 (+)NCBICelera
Cytogenetic Map11p15.1NCBI
HuRef1120,068,532 - 20,088,622 (+)NCBIHuRef
CHM1_11120,385,142 - 20,405,237 (+)NCBICHM1_1
T2T-CHM13v2.01120,484,405 - 20,504,464 (+)NCBIT2T-CHM13v2.0
Htatip2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39749,408,761 - 49,423,748 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl749,408,863 - 49,423,723 (+)EnsemblGRCm39 Ensembl
GRCm38749,759,045 - 49,774,000 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl749,759,115 - 49,773,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv37757,014,476 - 57,029,369 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36749,627,174 - 49,642,016 (+)NCBIMGSCv36mm8
Celera745,209,058 - 45,223,844 (+)NCBICelera
Cytogenetic Map7B4NCBI
cM Map731.44NCBI
Htatip2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554761,196,986 - 1,222,730 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554761,197,053 - 1,219,679 (+)NCBIChiLan1.0ChiLan1.0
HTATIP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2922,665,003 - 22,685,165 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11122,624,797 - 22,644,938 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01120,388,475 - 20,408,633 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11120,300,514 - 20,320,271 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1120,300,528 - 20,320,271 (+)Ensemblpanpan1.1panPan2
HTATIP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12142,386,568 - 42,402,962 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2142,385,480 - 42,402,960 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2141,863,579 - 41,879,999 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02143,508,416 - 43,525,298 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2143,508,147 - 43,525,273 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12142,510,443 - 42,527,103 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02142,686,207 - 42,702,947 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02143,067,674 - 43,084,591 (+)NCBIUU_Cfam_GSD_1.0
Htatip2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494742,593,660 - 42,642,829 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366541,315,862 - 1,333,005 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366541,315,921 - 1,332,926 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HTATIP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl239,034,013 - 39,055,315 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1239,035,337 - 39,052,178 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2241,963,512 - 41,980,422 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HTATIP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1144,624,782 - 44,643,188 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl144,624,734 - 44,643,121 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038141,959,157 - 141,977,902 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Htatip2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476611,649,834 - 11,669,418 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476611,650,643 - 11,667,338 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Htatip2
32 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:246
Count of miRNA genes:170
Interacting mature miRNAs:191
Transcripts:ENSRNOT00000036258
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)194494440117601394Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
61346Rf2Renal disease susceptibility QTL 23.7urine protein amount (VT:0005160)urine protein level (CMO:0000591)199267916144267916Rat
61399Tcat1Tongue tumor resistance QTL 13.3tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)199267916144267916Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 27 20 6 20 6 7 19 3
Low 43 30 21 13 21 8 11 68 28 22 8 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000036258   ⟹   ENSRNOP00000030758
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,473,577 - 99,488,629 (+)Ensembl
Rnor_6.0 Ensembl1105,094,411 - 105,109,461 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117631   ⟹   ENSRNOP00000092156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,469,245 - 99,488,503 (+)Ensembl
RefSeq Acc Id: NM_001106263   ⟹   NP_001099733
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81108,610,195 - 108,624,810 (+)NCBI
mRatBN7.2199,474,013 - 99,488,627 (+)NCBI
Rnor_6.01105,094,842 - 105,109,454 (+)NCBI
Rnor_5.01106,144,564 - 106,159,708 (+)NCBI
RGSC_v3.4199,563,187 - 99,577,802 (+)RGD
Celera193,673,035 - 93,687,653 (+)RGD
Sequence:
RefSeq Acc Id: XM_006229249   ⟹   XP_006229311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81108,609,733 - 108,624,810 (+)NCBI
mRatBN7.2199,473,572 - 99,488,632 (+)NCBI
Rnor_6.01105,094,403 - 105,109,459 (+)NCBI
Rnor_5.01106,144,564 - 106,159,708 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229250   ⟹   XP_006229312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81108,609,424 - 108,624,810 (+)NCBI
mRatBN7.2199,473,411 - 99,488,632 (+)NCBI
Rnor_6.01105,094,275 - 105,109,459 (+)NCBI
Rnor_5.01106,144,564 - 106,159,708 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229251   ⟹   XP_006229313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81108,609,696 - 108,624,810 (+)NCBI
mRatBN7.2199,473,536 - 99,488,632 (+)NCBI
Rnor_6.01105,094,272 - 105,109,459 (+)NCBI
Rnor_5.01106,144,564 - 106,159,708 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001099733   ⟸   NM_001106263
- UniProtKB: B0BNF8 (UniProtKB/TrEMBL),   G3V8Y4 (UniProtKB/TrEMBL),   A0A8I6AEZ6 (UniProtKB/TrEMBL),   A0A1L1WKF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229312   ⟸   XM_006229250
- Peptide Label: isoform X2
- UniProtKB: B0BNF8 (UniProtKB/TrEMBL),   G3V8Y4 (UniProtKB/TrEMBL),   A0A8I6AEZ6 (UniProtKB/TrEMBL),   A0A1L1WKF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229313   ⟸   XM_006229251
- Peptide Label: isoform X2
- UniProtKB: B0BNF8 (UniProtKB/TrEMBL),   G3V8Y4 (UniProtKB/TrEMBL),   A0A8I6AEZ6 (UniProtKB/TrEMBL),   A0A1L1WKF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229311   ⟸   XM_006229249
- Peptide Label: isoform X1
- UniProtKB: A0A0G2QC15 (UniProtKB/TrEMBL),   A6JBG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000030758   ⟸   ENSRNOT00000036258
RefSeq Acc Id: ENSRNOP00000092156   ⟸   ENSRNOT00000117631
Protein Domains
NAD(P)-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2QC15-F1-model_v2 AlphaFold A0A0G2QC15 1-275 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690077
Promoter ID:EPDNEW_R601
Type:initiation region
Name:Htatip2_1
Description:HIV-1 Tat interactive protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01105,094,370 - 105,094,430EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309941 AgrOrtholog
BioCyc Gene G2FUF-59560 BioCyc
Ensembl Genes ENSRNOG00000022189 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036258.6 UniProtKB/TrEMBL
  ENSRNOT00000117631 ENTREZGENE
  ENSRNOT00000117631.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7321759 IMAGE-MGC_LOAD
InterPro NAD(P)-bd_dom UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
KEGG Report rno:292935 UniProtKB/TrEMBL
MGC_CLONE MGC:188215 IMAGE-MGC_LOAD
NCBI Gene 292935 ENTREZGENE
PANTHER OXIDOREDUCTASE HTATIP2 UniProtKB/TrEMBL
  OXIDOREDUCTASE HTATIP2 UniProtKB/TrEMBL
Pfam NAD_binding_10 UniProtKB/TrEMBL
PhenoGen Htatip2 PhenoGen
RatGTEx ENSRNOG00000022189 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A0G2QC15 ENTREZGENE, UniProtKB/TrEMBL
  A0A1L1WKF6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AEZ6 ENTREZGENE, UniProtKB/TrEMBL
  A6JBG2 ENTREZGENE, UniProtKB/TrEMBL
  B0BNF8 ENTREZGENE, UniProtKB/TrEMBL
  G3V8Y4 ENTREZGENE
UniProt Secondary G3V8Y4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-01-12 Htatip2  HIV-1 Tat interactive protein 2  Htatip2  HIV-1 tat interactive protein 2, homolog (human)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Htatip2  HIV-1 tat interactive protein 2, homolog (human)   Htatip2_predicted  HIV-1 tat interactive protein 2, homolog (human) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Htatip2_predicted  HIV-1 tat interactive protein 2, homolog (human) (predicted)    HIV-1 Tat interactive protein 2 (predicted)  Name updated 1299863 APPROVED
2005-01-12 Htatip2_predicted  HIV-1 Tat interactive protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED