(+)-catechin multiple interactions ISO RGD:731013 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of CCN2 mRNA CTD PMID:24763279 (-)-epigallocatechin 3-gallate affects expression ISO RGD:731014 6480464 epigallocatechin gallate affects the expression of CCN2 CTD PMID:25955525 (20S)-ginsenoside Rg3 decreases expression ISO RGD:731013 6480464 ginsenoside Rg3 results in decreased expression of CCN2 mRNA CTD PMID:31916386 (R)-carnitine multiple interactions EXP 6480464 Carnitine inhibits the reaction [Sunitinib results in increased expression of CCN2 mRNA] CTD PMID:26581635 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of CCN2 protein CTD PMID:22691361 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane affects expression EXP 6480464 2 more ... CTD PMID:19414516 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions EXP 6480464 2 more ... CTD PMID:19414516 1,2-dimethylhydrazine increases expression ISO RGD:731014 6480464 1, 2-Dimethylhydrazine results in increased expression of CCN2 mRNA CTD PMID:22206623 1,3-dinitrobenzene increases expression EXP 6480464 3-dinitrobenzene results in increased expression of CCN2 mRNA CTD PMID:24140754 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of CCN2 mRNA CTD PMID:25380136 , PMID:30723492 1-nitropyrene increases expression ISO RGD:731013 6480464 1-nitropyrene results in increased expression of CCN2 mRNA CTD PMID:19041380 1-octadec-9-enoylglycero-3-phosphate increases expression EXP 6480464 lysophosphatidic acid results in increased expression of CCN2 protein CTD PMID:15200425 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO RGD:731014 6480464 N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 mRNA] CTD PMID:24706986 1-octadec-9-enoylglycero-3-phosphate increases expression ISO RGD:731014 6480464 lysophosphatidic acid results in increased expression of CCN2 mRNA CTD PMID:24706986 1-octadec-9-enoylglycero-3-phosphate multiple interactions EXP 6480464 Simvastatin inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein], Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein] CTD PMID:15200425 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO RGD:731013 6480464 15-deoxy-delta(12 more ... CTD PMID:19429239 17alpha-ethynylestradiol decreases expression ISO RGD:731013 6480464 Ethinyl Estradiol results in decreased expression of CCN2 mRNA CTD PMID:18936297 17alpha-ethynylestradiol affects expression ISO RGD:731013 6480464 Ethinyl Estradiol affects the expression of CCN2 mRNA CTD PMID:20170705 , PMID:26865667 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of CCN2 mRNA CTD PMID:20170705 , PMID:26865667 17beta-estradiol affects expression ISO RGD:731013 6480464 Estradiol affects the expression of CCN2 mRNA CTD PMID:14699072 , PMID:25321415 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CCN2 mRNA CTD PMID:32741896 17beta-estradiol increases expression ISO RGD:731013 6480464 Estradiol results in increased expression of CCN2 mRNA, Estradiol results in increased expression of CCN2 protein CTD PMID:19153601 more ... 17beta-estradiol multiple interactions ISO RGD:731013 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CCN2 mRNA more ... CTD PMID:20823114 more ... 17beta-estradiol increases expression ISO RGD:731014 6480464 Estradiol results in increased expression of CCN2 mRNA CTD PMID:19484750 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CCN2 mRNA CTD PMID:32741896 2,3,4,7,8-Pentachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:21724226 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:731013 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CCN2 mRNA CTD PMID:19684285 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:731014 6480464 Tetrachlorodibenzodioxin results in increased expression of CCN2 mRNA CTD PMID:15034205 , PMID:26290441 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:731014 6480464 [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of CCN2 mRNA CTD PMID:25975270 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:731013 6480464 Tetrachlorodibenzodioxin results in decreased expression of CCN2 mRNA CTD PMID:19684285 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of CCN2 mRNA CTD PMID:23196670 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCN2 mRNA] CTD PMID:23196670 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CCN2 mRNA CTD PMID:21724226 , PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:731014 6480464 Tetrachlorodibenzodioxin affects the expression of CCN2 mRNA CTD PMID:20702594 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:731013 6480464 Tetrachlorodibenzodioxin affects the expression of CCN2 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of CCN2 mRNA CTD PMID:22298810 , PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:731014 6480464 Tetrachlorodibenzodioxin results in decreased expression of CCN2 mRNA CTD PMID:19770486 , PMID:19933214 2,3,7,8-Tetrachlorodibenzofuran affects expression ISO RGD:731014 6480464 2 more ... CTD PMID:20702594 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:21724226 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:731014 6480464 Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA CTD PMID:25740948 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:731014 6480464 stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA] CTD PMID:25740948 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of CCN2 mRNA, 2-Acetylaminofluorene results in increased expression of CCN2 protein CTD PMID:15940639 2-acetamidofluorene multiple interactions EXP 6480464 Iloprost inhibits the reaction [2-Acetylaminofluorene results in increased expression of CCN2 mRNA] CTD PMID:15940639 2-amino-2-deoxy-D-glucopyranose increases expression EXP 6480464 Glucosamine analog results in increased expression of CCN2 mRNA CTD PMID:21466783 2-butoxyethanol increases expression ISO RGD:731014 6480464 n-butoxyethanol results in increased expression of CCN2 mRNA CTD PMID:19812364 2-methoxyethanol increases expression EXP 6480464 methyl cellosolve results in increased expression of CCN2 mRNA CTD PMID:21061450 2-tert-butylhydroquinone decreases expression ISO RGD:731014 6480464 2-tert-butylhydroquinone results in decreased expression of CCN2 mRNA CTD PMID:16014739 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions ISO RGD:731013 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]] CTD PMID:15298857 3',5'-cyclic AMP multiple interactions EXP 6480464 2 more ... CTD PMID:19414516 3,3',4,4',5-pentachlorobiphenyl affects expression ISO RGD:731014 6480464 3 more ... CTD PMID:20702594 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:23196670 , PMID:32119087 3,4-dichloroaniline decreases expression ISO RGD:731013 6480464 3, 4-dichloroaniline results in decreased expression of CCN2 mRNA CTD PMID:24172598 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:731014 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of CCN2 mRNA CTD PMID:20188158 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:731013 6480464 bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] CTD PMID:10026205 3-phenylprop-2-enal decreases expression ISO RGD:731013 6480464 cinnamaldehyde results in decreased expression of CCN2 mRNA CTD PMID:17178418 4'-epidoxorubicin increases expression ISO RGD:731014 6480464 Epirubicin results in increased expression of CCN2 mRNA CTD PMID:22712078 4'-epidoxorubicin multiple interactions ISO RGD:731014 6480464 Lovastatin inhibits the reaction [Epirubicin results in increased expression of CCN2 mRNA] CTD PMID:22712078 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of CCN2 mRNA CTD PMID:25380136 4,4'-sulfonyldiphenol increases expression ISO RGD:731013 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of CCN2 mRNA CTD PMID:25912373 4,4'-sulfonyldiphenol affects methylation ISO RGD:731014 6480464 bis(4-hydroxyphenyl)sulfone affects the methylation of CTGF gene CTD PMID:31683443 4,4'-sulfonyldiphenol increases methylation ISO RGD:731013 6480464 bis(4-hydroxyphenyl)sulfone results in increased methylation of CCN2 gene CTD PMID:31601247 4,4'-sulfonyldiphenol increases expression ISO RGD:731014 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of CCN2 mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol multiple interactions ISO RGD:731014 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of CCN2 mRNA CTD PMID:30951980 4-hydroxy-TEMPO decreases expression EXP 6480464 tempol results in decreased expression of CCN2 mRNA CTD PMID:16685210 4-hydroxyphenyl retinamide increases expression ISO RGD:731014 6480464 Fenretinide results in increased expression of CCN2 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine decreases expression ISO RGD:731014 6480464 Decitabine results in decreased expression of CCN2 mRNA CTD PMID:27915011 5-aza-2'-deoxycytidine increases expression ISO RGD:731013 6480464 Decitabine results in increased expression of CCN2 mRNA CTD PMID:21856257 5-aza-2'-deoxycytidine affects expression ISO RGD:731013 6480464 Decitabine affects the expression of CCN2 mRNA CTD PMID:23300844 5-fluorouracil affects expression ISO RGD:731013 6480464 Fluorouracil affects the expression of CCN2 mRNA CTD PMID:15205334 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of CCN2 mRNA CTD PMID:24780913 , PMID:25825206 6alpha-methylprednisolone increases expression ISO RGD:731013 6480464 Methylprednisolone results in increased expression of CCN2 mRNA CTD PMID:19192274 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:19480007 7,12-dimethyltetraphene increases expression ISO RGD:731014 6480464 9 more ... CTD PMID:32553695 acetaldehyde increases abundance ISO RGD:731014 6480464 CCN2 protein results in increased abundance of Acetaldehyde CTD PMID:19280452 acetaldehyde increases expression ISO RGD:731014 6480464 Acetaldehyde results in increased expression of CCN2 mRNA CTD PMID:19280452 acetaldehyde multiple interactions ISO RGD:731014 6480464 [Ethanol results in increased expression of CCN2 protein] which results in increased abundance of Acetaldehyde CTD PMID:19280452 acetamide increases expression EXP 6480464 acetamide results in increased expression of CCN2 mRNA CTD PMID:31881176 acetylsalicylic acid multiple interactions EXP 6480464 Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA], Aspirin inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA] CTD PMID:14586741 acrylamide increases expression ISO RGD:731013 6480464 Acrylamide results in increased expression of CCN2 mRNA CTD PMID:32763439 adenine multiple interactions EXP 6480464 camostat inhibits the reaction [Adenine results in increased expression of CCN2 mRNA] CTD PMID:25766432 adenine increases expression EXP 6480464 Adenine results in increased expression of CCN2 mRNA CTD PMID:25766432 afimoxifene affects response to substance ISO RGD:731013 6480464 CCN2 protein affects the susceptibility to afimoxifene CTD PMID:19153601 afimoxifene increases expression ISO RGD:731013 6480464 afimoxifene results in increased expression of CCN2 mRNA, afimoxifene results in increased expression of CCN2 protein CTD PMID:19153601 afimoxifene multiple interactions ISO RGD:731013 6480464 GPER1 protein affects the reaction [afimoxifene results in increased expression of CCN2 mRNA] CTD PMID:19153601 aflatoxin B1 decreases expression ISO RGD:731014 6480464 Aflatoxin B1 results in decreased expression of CCN2 mRNA CTD PMID:19770486 aflatoxin B1 decreases expression ISO RGD:731013 6480464 Aflatoxin B1 results in decreased expression of CCN2 mRNA CTD PMID:32234424 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of CCN2 mRNA CTD PMID:33354967 aflatoxin B1 increases expression ISO RGD:731013 6480464 Aflatoxin B1 results in increased expression of CCN2 mRNA CTD PMID:27153756 aflatoxin B1 decreases methylation ISO RGD:731013 6480464 Aflatoxin B1 results in decreased methylation of CCN2 gene CTD PMID:27153756 aflatoxin M1 decreases expression ISO RGD:731013 6480464 Aflatoxin M1 results in decreased expression of CCN2 mRNA CTD PMID:30928695 aldehydo-D-glucosamine increases expression EXP 6480464 Glucosamine analog results in increased expression of CCN2 mRNA CTD PMID:21466783 aldehydo-D-glucose multiple interactions ISO RGD:731013 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCN2 protein] more ... CTD PMID:10026205 more ... aldehydo-D-glucose increases expression ISO RGD:731014 6480464 Glucose results in increased expression of CCN2 mRNA CTD PMID:33270355 aldehydo-D-glucose multiple interactions ISO RGD:731014 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]], SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] CTD PMID:33270355 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of CCN2 mRNA, Glucose results in increased expression of CCN2 protein CTD PMID:14586741 more ... aldehydo-D-glucose multiple interactions EXP 6480464 Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] more ... CTD PMID:14586741 more ... aldehydo-D-glucose increases expression ISO RGD:731013 6480464 Glucose results in increased expression of CCN2 mRNA, Glucose results in increased expression of CCN2 protein CTD PMID:10026205 more ... aldosterone increases expression EXP 6480464 Aldosterone results in increased expression of CCN2 protein CTD PMID:17278980 aldosterone increases expression ISO RGD:731013 6480464 Aldosterone results in increased expression of CCN2 mRNA CTD PMID:30809271 aldosterone multiple interactions EXP 6480464 Spironolactone inhibits the reaction [Aldosterone results in increased expression of CCN2 protein] CTD PMID:17278980 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of CCN2 mRNA, Tretinoin results in increased expression of CCN2 protein CTD PMID:20488242 , PMID:21258935 all-trans-retinoic acid multiple interactions ISO RGD:731014 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of CCN2 mRNA more ... CTD PMID:30951980 all-trans-retinoic acid increases expression ISO RGD:731013 6480464 Tretinoin results in increased expression of CCN2 mRNA CTD PMID:23830798 all-trans-retinoic acid multiple interactions EXP 6480464 Tretinoin inhibits the reaction [nitrofen results in decreased expression of CCN2 mRNA], Tretinoin inhibits the reaction [nitrofen results in decreased expression of CCN2 protein] CTD PMID:21258935 alpha-D-galactose multiple interactions EXP 6480464 Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased expression of CCN2 protein] CTD PMID:30367734 alpha-D-galactose increases expression EXP 6480464 Galactose results in increased expression of CCN2 protein CTD PMID:30367734 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CCN2 mRNA CTD PMID:16483693 Ammothamnine multiple interactions ISO RGD:731014 6480464 oxymatrine inhibits the reaction [SNHG6 results in increased expression of CCN2 protein] CTD PMID:35785413 andrographolide multiple interactions ISO RGD:731014 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CCN2 mRNA CTD PMID:19737545 anthocyanin decreases expression ISO RGD:731014 6480464 Anthocyanins results in decreased expression of CCN2 mRNA CTD PMID:30056145 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:731013 6480464 [pyrazolanthrone co-treated with U 0126] inhibits the reaction [fisetin results in decreased expression of CCN2 protein] more ... CTD PMID:31044527 antimycin A increases expression ISO RGD:731013 6480464 Antimycin A results in increased expression of CCN2 mRNA CTD PMID:33512557 antirheumatic drug decreases expression ISO RGD:731013 6480464 Antirheumatic Agents results in decreased expression of CCN2 mRNA CTD PMID:24449571 aristolochic acid A multiple interactions ISO RGD:731014 6480464 aristolochic acid I inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of CCN2 protein] CTD PMID:24412304 aristolochic acid A decreases expression ISO RGD:731013 6480464 aristolochic acid I results in decreased expression of CCN2 mRNA, aristolochic acid I results in decreased expression of CCN2 protein CTD PMID:33212167 aristolochic acids increases expression EXP 6480464 Aristolochic Acids results in increased expression of CCN2 mRNA CTD PMID:19717638 arsane affects expression ISO RGD:731013 6480464 Arsenic affects the expression of CCN2 protein CTD PMID:24675094 arsane multiple interactions ISO RGD:731014 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Dietary Fats] results in increased expression of CCN2 protein, [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CCN2 protein CTD PMID:31238026 arsane increases expression ISO RGD:731014 6480464 Arsenic results in increased expression of CCN2 mRNA CTD PMID:23942117 arsane increases expression EXP 6480464 Arsenic results in increased expression of CCN2 mRNA CTD PMID:24348802 arsane multiple interactions EXP 6480464 Grape Seed Extract inhibits the reaction [Arsenic results in increased expression of CCN2 mRNA] CTD PMID:24348802 arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of CCN2 mRNA CTD PMID:24348802 arsenic atom multiple interactions ISO RGD:731014 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Dietary Fats] results in increased expression of CCN2 protein, [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CCN2 protein CTD PMID:31238026 arsenic atom increases expression ISO RGD:731014 6480464 Arsenic results in increased expression of CCN2 mRNA CTD PMID:23942117 arsenic atom affects expression ISO RGD:731013 6480464 Arsenic affects the expression of CCN2 protein CTD PMID:24675094 arsenic atom multiple interactions EXP 6480464 Grape Seed Extract inhibits the reaction [Arsenic results in increased expression of CCN2 mRNA] CTD PMID:24348802 arsenite(3-) multiple interactions ISO RGD:731013 6480464 arsenite inhibits the reaction [Fulvestrant results in increased expression of CCN2 mRNA] CTD PMID:31646340 arsenite(3-) decreases expression ISO RGD:731013 6480464 arsenite results in decreased expression of CCN2 mRNA CTD PMID:31646340 arsenous acid multiple interactions ISO RGD:731013 6480464 Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA] CTD PMID:24762191 asbestos decreases expression ISO RGD:731013 6480464 Asbestos results in decreased expression of CCN2 mRNA CTD PMID:22076105 atrazine increases expression ISO RGD:731013 6480464 Atrazine results in increased expression of CCN2 mRNA, Atrazine results in increased expression of CCN2 protein CTD PMID:25616260 atrazine multiple interactions ISO RGD:731013 6480464 ESR1 protein promotes the reaction [Atrazine results in increased expression of CCN2 protein], GPER1 protein promotes the reaction [Atrazine results in increased expression of CCN2 protein] CTD PMID:25616260 bazedoxifene increases expression ISO RGD:731013 6480464 bazedoxifene results in increased expression of CCN2 mRNA CTD PMID:19914376 belinostat increases expression ISO RGD:731013 6480464 belinostat results in increased expression of CCN2 mRNA CTD PMID:19606018 , PMID:23671600 benazepril decreases expression EXP 6480464 benazepril results in decreased expression of CCN2 mRNA CTD PMID:17121042 benzalkonium chloride decreases expression ISO RGD:731013 6480464 Benzalkonium Compounds results in decreased expression of CCN2 mRNA CTD PMID:25377654 benzo[a]pyrene decreases expression ISO RGD:731013 6480464 Benzo(a)pyrene results in decreased expression of CCN2 mRNA CTD PMID:20106945 , PMID:21632981 benzo[a]pyrene affects methylation ISO RGD:731013 6480464 Benzo(a)pyrene affects the methylation of CCN2 3' UTR CTD PMID:27901495 benzo[a]pyrene decreases methylation ISO RGD:731013 6480464 Benzo(a)pyrene results in decreased methylation of CCN2 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:731014 6480464 Benzo(a)pyrene results in decreased expression of CCN2 mRNA CTD PMID:15034205 , PMID:19770486 benzo[a]pyrene multiple interactions ISO RGD:731014 6480464 AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of CCN2 mRNA] CTD PMID:15034205 benzo[a]pyrene increases expression ISO RGD:731014 6480464 Benzo(a)pyrene metabolite results in increased expression of CCN2 mRNA, Benzo(a)pyrene results in increased expression of CCN2 mRNA CTD PMID:21569818 more ... benzo[a]pyrene diol epoxide I decreases expression ISO RGD:731013 6480464 7 more ... CTD PMID:20018196 beta-D-glucosamine increases expression EXP 6480464 Glucosamine analog results in increased expression of CCN2 mRNA CTD PMID:21466783 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN2 mRNA CTD PMID:18164116 beta-naphthoflavone decreases expression ISO RGD:731013 6480464 beta-Naphthoflavone results in decreased expression of CCN2 mRNA CTD PMID:19737606 , PMID:32151702 beta-naphthoflavone multiple interactions ISO RGD:731014 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CCN2 mRNA CTD PMID:19737545 Betanin multiple interactions EXP 6480464 betanin inhibits the reaction [Fructose results in increased expression of CCN2 protein] CTD PMID:25559852 bezafibrate multiple interactions ISO RGD:731013 6480464 Bezafibrate inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:19429239 bis(2-chloroethyl) sulfide increases expression ISO RGD:731013 6480464 Mustard Gas results in increased expression of CCN2 mRNA CTD PMID:16173061 , PMID:25102026 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of CCN2 protein CTD PMID:29669060 bisphenol A affects expression ISO RGD:731013 6480464 bisphenol A affects the expression of CCN2 mRNA CTD PMID:20170705 , PMID:30903817 bisphenol A increases expression ISO RGD:731014 6480464 bisphenol A results in increased expression of CCN2 mRNA CTD PMID:30951980 , PMID:33912069 bisphenol A multiple interactions ISO RGD:731014 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of CCN2 mRNA CTD PMID:30951980 bisphenol A decreases expression ISO RGD:731013 6480464 bisphenol A results in decreased expression of CCN2 mRNA CTD PMID:27685785 more ... bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CCN2 mRNA, bisphenol A results in decreased expression of CCN2 protein CTD PMID:24552547 , PMID:34947998 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CCN2 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:731013 6480464 bisphenol A promotes the reaction [CCN2 protein binds to ESR1 protein], GPER1 mRNA affects the reaction [bisphenol A results in increased expression of CCN2 protein] CTD PMID:22552965 , PMID:27156127 bisphenol A increases expression ISO RGD:731013 6480464 bisphenol A results in increased expression of CCN2 mRNA, bisphenol A results in increased expression of CCN2 protein CTD PMID:22552965 bisphenol F multiple interactions ISO RGD:731014 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of CCN2 mRNA CTD PMID:30951980 bisphenol F increases expression ISO RGD:731014 6480464 bisphenol F results in increased expression of CCN2 mRNA CTD PMID:30951980 bleomycin A2 multiple interactions ISO RGD:731014 6480464 [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA] more ... CTD PMID:19080365 more ... bleomycin A2 increases expression ISO RGD:731014 6480464 Bleomycin results in increased expression of CCN2 mRNA, Bleomycin results in increased expression of CCN2 protein CTD PMID:19080365 more ... bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of CCN2 mRNA CTD PMID:32479839 bucladesine multiple interactions ISO RGD:731013 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CCN2 mRNA CTD PMID:20823114 buta-1,3-diene increases expression ISO RGD:731014 6480464 1, 3-butadiene results in increased expression of CCN2 mRNA CTD PMID:29038090 cadmium atom multiple interactions ISO RGD:731013 6480464 Cadmium inhibits the reaction [Glucose results in increased expression of CCN2 protein], Fulvestrant inhibits the reaction [Cadmium results in decreased expression of CCN2 mRNA] CTD PMID:19369054 , PMID:31646340 cadmium atom decreases expression ISO RGD:731013 6480464 Cadmium results in decreased expression of CCN2 mRNA CTD PMID:31646340 cadmium atom multiple interactions ISO RGD:731014 6480464 [[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with Dietary Fats] results in increased expression of CCN2 mRNA, [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCN2 mRNA CTD PMID:30912652 , PMID:31904401 cadmium dichloride affects expression EXP 6480464 Cadmium Chloride affects the expression of CCN2 mRNA CTD PMID:22110744 cadmium dichloride decreases expression ISO RGD:731013 6480464 Cadmium Chloride results in decreased expression of CCN2 mRNA CTD PMID:26314618 cadmium dichloride increases expression ISO RGD:731013 6480464 Cadmium Chloride results in increased expression of CCN2 mRNA CTD PMID:26472689 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of CCN2 mRNA CTD PMID:33453195 cadmium dichloride multiple interactions ISO RGD:731014 6480464 [[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with Dietary Fats] results in increased expression of CCN2 mRNA more ... CTD PMID:20371981 more ... calciol decreases expression ISO RGD:731014 6480464 Cholecalciferol results in decreased expression of CCN2 mRNA CTD PMID:16508948 calciol increases expression ISO RGD:731014 6480464 Cholecalciferol results in increased expression of CCN2 mRNA CTD PMID:17170073 camostat multiple interactions EXP 6480464 camostat inhibits the reaction [Adenine results in increased expression of CCN2 mRNA], camostat inhibits the reaction [PLG protein modified form results in increased expression of CCN2 mRNA] CTD PMID:25766432 , PMID:27773435 candesartan decreases expression EXP 6480464 candesartan results in decreased expression of CCN2 mRNA CTD PMID:16685210 Candesartan cilexetil multiple interactions EXP 6480464 candesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of CCN2 protein] CTD PMID:27889505 cannabidiol increases expression ISO RGD:731013 6480464 Cannabidiol results in increased expression of CCN2 mRNA CTD PMID:33244087 carbamazepine affects expression ISO RGD:731013 6480464 Carbamazepine affects the expression of CCN2 mRNA CTD PMID:25979313 carbon nanotube increases expression ISO RGD:731013 6480464 Nanotubes, Carbon results in increased expression of CCN2 mRNA CTD PMID:22076105 carbon nanotube decreases expression ISO RGD:731014 6480464 Nanotubes, Carbon results in decreased expression of CCN2 mRNA CTD PMID:25554681 carbon nanotube increases expression ISO RGD:731014 6480464 Nanotubes more ... CTD PMID:25554681 , PMID:25620056 carbonyl sulfide increases expression EXP 6480464 carbonyl sulfide results in increased expression of CCN2 mRNA CTD PMID:19395590 cefaloridine decreases expression EXP 6480464 Cephaloridine results in decreased expression of CCN2 mRNA CTD PMID:18500788 CGP 52608 multiple interactions ISO RGD:731013 6480464 CGP 52608 promotes the reaction [RORA protein binds to CCN2 gene] CTD PMID:28238834 chlordecone decreases expression ISO RGD:731014 6480464 Chlordecone results in decreased expression of CCN2 mRNA CTD PMID:33711761 chloropicrin increases expression ISO RGD:731013 6480464 chloropicrin results in increased expression of CCN2 mRNA CTD PMID:26352163 chloroprene increases expression ISO RGD:731014 6480464 Chloroprene results in increased expression of CCN2 mRNA CTD PMID:23125180 chlorpromazine decreases expression ISO RGD:731013 6480464 Chlorpromazine results in decreased expression of CCN2 mRNA, Chlorpromazine results in decreased expression of CCN2 protein CTD PMID:30703373 choline multiple interactions ISO RGD:731014 6480464 [Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CCN2 mRNA more ... CTD PMID:18991162 more ... cisplatin increases expression ISO RGD:731014 6480464 Cisplatin results in increased expression of CCN2 mRNA CTD PMID:21151649 cisplatin decreases expression ISO RGD:731013 6480464 Cisplatin results in decreased expression of CCN2 mRNA CTD PMID:27392435 cisplatin increases expression ISO RGD:731013 6480464 Cisplatin results in increased expression of CCN2 mRNA CTD PMID:33545341 cisplatin affects expression ISO RGD:731013 6480464 Cisplatin affects the expression of CCN2 mRNA CTD PMID:23300844 cisplatin multiple interactions ISO RGD:731013 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of CCN2 mRNA, [Cisplatin co-treated with Paclitaxel] affects the expression of CCN2 mRNA CTD PMID:20705681 , PMID:27392435 clobetasol increases expression ISO RGD:731014 6480464 Clobetasol results in increased expression of CCN2 mRNA CTD PMID:27462272 cobalt atom decreases expression EXP 6480464 Cobalt results in decreased expression of CCN2 mRNA CTD PMID:17967803 cobalt dichloride multiple interactions ISO RGD:731013 6480464 cobaltous chloride promotes the reaction [HIF1A protein results in increased expression of CCN2 mRNA] more ... CTD PMID:17034590 cobalt dichloride decreases expression ISO RGD:731013 6480464 cobaltous chloride results in decreased expression of CCN2 mRNA CTD PMID:19320972 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of CCN2 mRNA CTD PMID:24386269 cobalt dichloride increases expression ISO RGD:731013 6480464 cobaltous chloride results in increased expression of CCN2 mRNA CTD PMID:17034590 , PMID:19376846 cocaine decreases expression ISO RGD:731013 6480464 Cocaine results in decreased expression of CCN2 mRNA, Cocaine results in decreased expression of CCN2 protein CTD PMID:18000554 coenzyme Q10 multiple interactions EXP 6480464 coenzyme Q10 inhibits the reaction [Doxorubicin results in increased expression of CCN2 protein] CTD PMID:27087047 copper atom multiple interactions ISO RGD:731013 6480464 [NSC 689534 binds to Copper] which results in increased expression of CCN2 mRNA CTD PMID:20971185 copper atom increases expression EXP 6480464 Copper results in increased expression of CCN2 mRNA CTD PMID:30556269 copper(0) multiple interactions ISO RGD:731013 6480464 [NSC 689534 binds to Copper] which results in increased expression of CCN2 mRNA CTD PMID:20971185 copper(0) increases expression EXP 6480464 Copper results in increased expression of CCN2 mRNA CTD PMID:30556269 copper(II) sulfate affects expression ISO RGD:731013 6480464 Copper Sulfate affects the expression of CCN2 mRNA CTD PMID:19549813 crocidolite asbestos increases expression ISO RGD:731013 6480464 Asbestos, Crocidolite results in increased expression of CCN2 mRNA CTD PMID:18687144 curcumin decreases expression ISO RGD:731013 6480464 Curcumin results in decreased expression of CCN2 mRNA, Curcumin results in decreased expression of CCN2 protein CTD PMID:17965732 , PMID:19764552 curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of CCN2 protein CTD PMID:17965732 curcumin multiple interactions ISO RGD:731013 6480464 IKBKB protein inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA] more ... CTD PMID:17965732 cycloheximide increases expression ISO RGD:731013 6480464 Cycloheximide results in increased expression of CCN2 mRNA CTD PMID:19684285 cycloheximide multiple interactions ISO RGD:731013 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CCN2 mRNA CTD PMID:19684285 cyclosporin A affects expression ISO RGD:731013 6480464 Cyclosporine affects the expression of CCN2 mRNA CTD PMID:20106945 cyclosporin A affects expression EXP 6480464 Cyclosporine affects the expression of CCN2 mRNA, Cyclosporine affects the expression of CCN2 protein CTD PMID:24971338 cyclosporin A decreases expression ISO RGD:731013 6480464 Cyclosporine results in decreased expression of CCN2 mRNA CTD PMID:25562108 , PMID:27989131 cyclosporin A multiple interactions ISO RGD:731013 6480464 [Cyclosporine co-treated with Cholic Acids] affects the expression of CCN2 mRNA CTD PMID:27344345 cyclosporin A multiple interactions ISO RGD:731014 6480464 Cyclosporine results in increased expression of and results in increased secretion of CCN2 protein CTD PMID:21354196 cyclosporin A increases expression ISO RGD:731014 6480464 Cyclosporine results in increased expression of CCN2 mRNA CTD PMID:21354196 cyclosporin A increases expression ISO RGD:731013 6480464 Cyclosporine results in increased expression of CCN2 mRNA CTD PMID:21632981 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of CCN2 mRNA CTD PMID:21865292 D-glucose multiple interactions ISO RGD:731013 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCN2 protein] more ... CTD PMID:10026205 more ... D-glucose multiple interactions ISO RGD:731014 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]], SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] CTD PMID:33270355 D-glucose increases expression ISO RGD:731014 6480464 Glucose results in increased expression of CCN2 mRNA CTD PMID:33270355 D-glucose increases expression EXP 6480464 Glucose results in increased expression of CCN2 mRNA, Glucose results in increased expression of CCN2 protein CTD PMID:14586741 more ... D-glucose multiple interactions EXP 6480464 Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] more ... CTD PMID:14586741 more ... D-glucose increases expression ISO RGD:731013 6480464 Glucose results in increased expression of CCN2 mRNA, Glucose results in increased expression of CCN2 protein CTD PMID:10026205 more ... DDT decreases expression EXP 6480464 DDT results in decreased expression of CCN2 mRNA CTD PMID:30207508 deoxynivalenol increases expression ISO RGD:731013 6480464 deoxynivalenol results in increased expression of CCN2 mRNA CTD PMID:35588983 dexamethasone increases expression ISO RGD:731014 6480464 Dexamethasone results in increased expression of CCN2 mRNA CTD PMID:22733784 Diallyl sulfide multiple interactions ISO RGD:731014 6480464 allyl sulfide inhibits the reaction [Ethanol results in increased expression of CCN2 mRNA], allyl sulfide inhibits the reaction [Ethanol results in increased expression of CCN2 protein] CTD PMID:19280452 diarsenic trioxide multiple interactions ISO RGD:731013 6480464 Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA] CTD PMID:24762191 dibenz[a,h]anthracene increases expression ISO RGD:731014 6480464 1 more ... CTD PMID:26377693 dibenzo[a,l]pyrene increases expression ISO RGD:731013 6480464 dibenzo(a, l)pyrene results in increased expression of CCN2 mRNA CTD PMID:15735009 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of CCN2 mRNA CTD PMID:21266533 dibutyl phthalate increases expression ISO RGD:731014 6480464 Dibutyl Phthalate results in increased expression of CCN2 mRNA CTD PMID:17361019 , PMID:21266533 dichloroacetic acid decreases expression ISO RGD:731014 6480464 Dichloroacetic Acid results in decreased expression of CCN2 mRNA CTD PMID:28962523 dichloroacetic acid decreases expression ISO RGD:731013 6480464 Dichloroacetic Acid results in decreased expression of CCN2 mRNA CTD PMID:33405312 dicrotophos increases expression ISO RGD:731013 6480464 dicrotophos results in increased expression of CCN2 mRNA CTD PMID:28302478 dioxygen affects expression ISO RGD:731014 6480464 Oxygen deficiency affects the expression of CCN2 mRNA CTD PMID:17193925 dioxygen multiple interactions ISO RGD:731014 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of CCN2 mRNA more ... CTD PMID:30096613 , PMID:30529165 dioxygen increases expression ISO RGD:731014 6480464 Oxygen deficiency results in increased expression of CCN2 protein CTD PMID:24657099 , PMID:30096613 dioxygen increases expression EXP 6480464 Oxygen results in increased expression of CCN2 mRNA CTD PMID:22911455 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of CCN2 mRNA, CCN2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 , PMID:33729688 diuron increases expression EXP 6480464 Diuron results in increased expression of CCN2 mRNA CTD PMID:21551480 diuron decreases expression ISO RGD:731013 6480464 Diuron metabolite results in decreased expression of CCN2 mRNA CTD PMID:24172598 divanadium pentaoxide decreases expression ISO RGD:731013 6480464 vanadium pentoxide results in decreased expression of CCN2 mRNA CTD PMID:17459161 dorsomorphin multiple interactions ISO RGD:731013 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin affects expression ISO RGD:731013 6480464 Doxorubicin affects the expression of CCN2 mRNA CTD PMID:15205334 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of CCN2 mRNA, Doxorubicin results in increased expression of CCN2 protein CTD PMID:27087047 , PMID:31307187 doxorubicin multiple interactions EXP 6480464 coenzyme Q10 inhibits the reaction [Doxorubicin results in increased expression of CCN2 protein], paeonol inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA] CTD PMID:27087047 , PMID:31307187 doxorubicin multiple interactions ISO RGD:731014 6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA], NSC 23766 inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA] CTD PMID:22712078 , PMID:28710503 doxorubicin increases expression ISO RGD:731014 6480464 Doxorubicin results in increased expression of CCN2 mRNA CTD PMID:22712078 , PMID:28710503 doxorubicin increases expression ISO RGD:731013 6480464 Doxorubicin results in increased expression of CCN2 mRNA CTD PMID:16579640 more ... doxorubicin affects expression ISO RGD:731014 6480464 Doxorubicin affects the expression of CCN2 mRNA CTD PMID:15033991 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor multiple interactions EXP 6480464 7-Ala-angiotensin (1-7) inhibits the reaction [Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [AGT protein results in increased expression of CCN2 protein]], Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [AGT protein results in increased expression of CCN2 protein] CTD PMID:19793108 enalapril decreases expression EXP 6480464 Enalapril results in decreased expression of CCN2 mRNA, Enalapril results in decreased expression of CCN2 protein CTD PMID:18812665 , PMID:19349682 enalapril multiple interactions EXP 6480464 Enalapril inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] CTD PMID:21416479 enalapril decreases expression ISO RGD:731014 6480464 Enalapril results in decreased expression of CCN2 mRNA CTD PMID:25037058 endosulfan affects expression EXP 6480464 Endosulfan affects the expression of CCN2 mRNA CTD PMID:29391264 erythromycin estolate decreases expression EXP 6480464 Erythromycin Estolate results in decreased expression of CCN2 mRNA CTD PMID:24412560 ethanol multiple interactions ISO RGD:731014 6480464 [Ethanol co-treated with Thioacetamide] results in increased expression of CCN2 mRNA more ... CTD PMID:19280452 , PMID:21863215 ethanol decreases expression ISO RGD:731013 6480464 Ethanol results in decreased expression of CCN2 mRNA CTD PMID:31059573 ethanol multiple interactions ISO RGD:731013 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CCN2 mRNA CTD PMID:29432896 ethanol increases expression EXP 6480464 Ethanol results in increased expression of CCN2 mRNA CTD PMID:16098508 ethanol increases expression ISO RGD:731014 6480464 Ethanol results in increased expression of CCN2 protein CTD PMID:19280452 , PMID:28962519 etoposide increases expression ISO RGD:731013 6480464 Etoposide results in increased expression of CCN2 mRNA CTD PMID:29397400 ferulic acid multiple interactions ISO RGD:731014 6480464 ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of CTGF protein] CTD PMID:33428986 fipronil increases expression EXP 6480464 fipronil results in increased expression of CCN2 mRNA CTD PMID:34044035 fisetin multiple interactions ISO RGD:731013 6480464 [pyrazolanthrone co-treated with U 0126] inhibits the reaction [fisetin results in decreased expression of CCN2 protein] more ... CTD PMID:31044527 fisetin decreases expression ISO RGD:731013 6480464 fisetin results in decreased expression of CCN2 protein CTD PMID:31044527 folic acid multiple interactions ISO RGD:731014 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of CCN2 more ... CTD PMID:20938992 folic acid decreases expression ISO RGD:731014 6480464 Folic Acid results in decreased expression of CCN2 mRNA CTD PMID:25629700 fomepizole multiple interactions ISO RGD:731014 6480464 Fomepizole inhibits the reaction [Ethanol results in increased expression of CCN2 mRNA], Fomepizole inhibits the reaction [Ethanol results in increased expression of CCN2 protein] CTD PMID:19280452 fonofos increases methylation ISO RGD:731013 6480464 Fonofos results in increased methylation of CCN2 promoter CTD PMID:22847954 formaldehyde increases expression ISO RGD:731013 6480464 Formaldehyde results in increased expression of CCN2 mRNA CTD PMID:20655997 more ... fructose multiple interactions EXP 6480464 betanin inhibits the reaction [Fructose results in increased expression of CCN2 protein] CTD PMID:25559852 fructose increases expression EXP 6480464 Fructose results in increased expression of CCN2 protein CTD PMID:25559852 fulvestrant increases expression ISO RGD:731013 6480464 Fulvestrant results in increased expression of CCN2 mRNA CTD PMID:31646340 fulvestrant multiple interactions ISO RGD:731013 6480464 arsenite inhibits the reaction [Fulvestrant results in increased expression of CCN2 mRNA] more ... CTD PMID:31646340 furan increases expression EXP 6480464 furan results in increased expression of CCN2 mRNA, furan results in increased expression of CCN2 protein CTD PMID:27371368 , PMID:27387713 galactose multiple interactions EXP 6480464 Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased expression of CCN2 protein] CTD PMID:30367734 galactose increases expression EXP 6480464 Galactose results in increased expression of CCN2 protein CTD PMID:30367734 genistein decreases expression ISO RGD:731013 6480464 Genistein results in decreased expression of CCN2 mRNA CTD PMID:20884965 genistein affects expression ISO RGD:731013 6480464 Genistein affects the expression of CCN2 mRNA CTD PMID:26865667 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of CCN2 mRNA CTD PMID:33387578 glucose multiple interactions ISO RGD:731013 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCN2 protein] more ... CTD PMID:10026205 more ... glucose increases expression ISO RGD:731014 6480464 Glucose results in increased expression of CCN2 mRNA CTD PMID:33270355 glucose multiple interactions ISO RGD:731014 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]], SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] CTD PMID:33270355 glucose increases expression EXP 6480464 Glucose results in increased expression of CCN2 mRNA, Glucose results in increased expression of CCN2 protein CTD PMID:14586741 more ... glucose multiple interactions EXP 6480464 Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] more ... CTD PMID:14586741 more ... glucose increases expression ISO RGD:731013 6480464 Glucose results in increased expression of CCN2 mRNA, Glucose results in increased expression of CCN2 protein CTD PMID:10026205 more ... hexadecanoic acid multiple interactions EXP 6480464 CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein] more ... CTD PMID:34310909 hexadecanoic acid increases expression EXP 6480464 Palmitic Acid results in increased expression of CCN2 protein CTD PMID:34310909 Honokiol multiple interactions ISO RGD:731014 6480464 honokiol inhibits the reaction [Bleomycin results in increased expression of CCN2 protein] CTD PMID:32032644 Honokiol multiple interactions ISO RGD:731013 6480464 honokiol inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA], honokiol inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:21265825 , PMID:32032644 Honokiol multiple interactions EXP 6480464 honokiol inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:21265825 Honokiol affects expression EXP 6480464 honokiol affects the expression of CCN2 mRNA CTD PMID:21265825 hydrogen cyanide increases expression ISO RGD:731014 6480464 Hydrogen Cyanide results in increased expression of CCN2 mRNA CTD PMID:33914522 hydrogen peroxide increases expression ISO RGD:731013 6480464 Hydrogen Peroxide results in increased expression of CCN2 mRNA, Hydrogen Peroxide results in increased expression of CCN2 protein CTD PMID:15147944 , PMID:32949572 hydrogen peroxide affects expression ISO RGD:731013 6480464 Hydrogen Peroxide affects the expression of CCN2 mRNA CTD PMID:20044591 , PMID:23410634 hydrogen sulfide increases expression ISO RGD:731014 6480464 Hydrogen Sulfide results in increased expression of CCN2 mRNA CTD PMID:31843631 hydroquinone increases expression ISO RGD:731013 6480464 hydroquinone results in increased expression of CCN2 mRNA CTD PMID:31256213 idebenone multiple interactions EXP 6480464 idebenone inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] CTD PMID:28648635 , PMID:34175429 iloprost multiple interactions EXP 6480464 Iloprost inhibits the reaction [2-Acetylaminofluorene results in increased expression of CCN2 mRNA] CTD PMID:15940639 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of CCN2 mRNA CTD PMID:21396975 indometacin increases expression EXP 6480464 Indomethacin results in increased expression of CCN2 mRNA CTD PMID:12077510 irinotecan increases expression ISO RGD:731013 6480464 Irinotecan results in increased expression of CCN2 mRNA CTD PMID:20185912 isobutanol multiple interactions ISO RGD:731013 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CCN2 mRNA CTD PMID:29432896 isoprenaline increases expression ISO RGD:731014 6480464 Isoproterenol results in increased expression of CCN2 mRNA CTD PMID:20003209 isoprenaline multiple interactions EXP 6480464 Quercetin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA] more ... CTD PMID:24117263 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of CCN2 mRNA, Isoproterenol results in increased expression of CCN2 protein CTD PMID:24117263 isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of CCN2 mRNA CTD PMID:24286936 jaspamide multiple interactions ISO RGD:731013 6480464 jasplakinolide results in increased expression of and results in increased secretion of CCN2 protein, YAP1 protein affects the reaction [jasplakinolide results in increased expression of CCN2 protein] CTD PMID:24040060 jaspamide increases expression ISO RGD:731013 6480464 jasplakinolide results in increased expression of CCN2 mRNA CTD PMID:24040060 , PMID:25690654 jaspamide increases expression ISO RGD:731014 6480464 jasplakinolide results in increased expression of CCN2 mRNA CTD PMID:25690654 L-ascorbic acid 2-phosphate decreases expression ISO RGD:731013 6480464 ascorbate-2-phosphate results in decreased expression of CCN2 mRNA CTD PMID:17306970 L-methionine multiple interactions ISO RGD:731014 6480464 [Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CCN2 mRNA more ... CTD PMID:18991162 more ... lead diacetate decreases expression ISO RGD:731014 6480464 lead acetate results in decreased expression of CCN2 mRNA CTD PMID:25270620 leflunomide increases expression ISO RGD:731013 6480464 Leflunomide results in increased expression of CCN2 mRNA CTD PMID:28988120 letrozole increases expression EXP 6480464 Letrozole results in increased expression of CCN2 protein CTD PMID:33491863 letrozole multiple interactions EXP 6480464 ADM protein inhibits the reaction [Letrozole results in increased expression of CCN2 protein] CTD PMID:33491863 Licochalcone A decreases expression ISO RGD:731013 6480464 licochalcone A results in decreased expression of CCN2 mRNA CTD PMID:34845814 Licochalcone B increases expression ISO RGD:731013 6480464 licochalcone B results in increased expression of CCN2 mRNA CTD PMID:33647349 limonin decreases expression ISO RGD:731013 6480464 limonin results in decreased expression of CCN2 mRNA CTD PMID:30738134 lipopolysaccharide multiple interactions ISO RGD:731013 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of CCN2 mRNA more ... CTD PMID:17965732 more ... lipopolysaccharide increases expression ISO RGD:731013 6480464 Lipopolysaccharides results in increased expression of CCN2 mRNA CTD PMID:35811015 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of CCN2 mRNA, Lipopolysaccharides results in increased expression of CCN2 protein CTD PMID:17965732 lipopolysaccharide multiple interactions ISO RGD:731014 6480464 [[[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] which results in increased abundance of Nitric Oxide] which results in decreased expression of CCN2 protein more ... CTD PMID:24412304 lovastatin multiple interactions ISO RGD:731014 6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA], Lovastatin inhibits the reaction [Epirubicin results in increased expression of CCN2 mRNA] CTD PMID:22712078 , PMID:28710503 LY294002 multiple interactions ISO RGD:731013 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one analog inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:26054450 LY294002 multiple interactions ISO RGD:731014 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]] CTD PMID:33270355 manganese(II) chloride increases expression ISO RGD:731014 6480464 manganese chloride results in increased expression of CCN2 mRNA CTD PMID:17467022 manganese(II) chloride increases methylation EXP 6480464 manganese chloride results in increased methylation of CCN2 gene CTD PMID:28801915 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of CCN2 mRNA CTD PMID:28801915 mechlorethamine increases expression EXP 6480464 Mechlorethamine results in increased expression of CCN2 mRNA, Mechlorethamine results in increased expression of CCN2 protein CTD PMID:20883710 , PMID:26273949 medroxyprogesterone acetate multiple interactions ISO RGD:731013 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CCN2 mRNA CTD PMID:20823114 menadione affects expression ISO RGD:731013 6480464 Vitamin K 3 affects the expression of CCN2 mRNA CTD PMID:20044591 , PMID:23410634 mercury dibromide multiple interactions ISO RGD:731013 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCN2 mRNA CTD PMID:27188386 mercury dichloride decreases expression EXP 6480464 Mercuric Chloride results in decreased expression of CCN2 mRNA CTD PMID:16507785 metformin decreases expression EXP 6480464 Metformin results in decreased expression of CCN2 mRNA CTD PMID:31324951 methotrexate decreases expression ISO RGD:731013 6480464 Methotrexate results in decreased expression of CCN2 mRNA CTD PMID:17400583 methotrexate decreases response to substance ISO RGD:731013 6480464 CCN2 mRNA results in decreased susceptibility to Methotrexate CTD PMID:24154679 methotrexate increases expression ISO RGD:731013 6480464 Methotrexate results in increased expression of CCN2 mRNA CTD PMID:19192274 methylisothiazolinone increases expression ISO RGD:731013 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of CCN2 mRNA CTD PMID:31629900 methylmercury chloride increases expression ISO RGD:731013 6480464 methylmercuric chloride results in increased expression of CCN2 mRNA CTD PMID:23179753 more ... methylparaben decreases expression ISO RGD:731013 6480464 methylparaben results in decreased expression of CCN2 mRNA CTD PMID:31745603 metoprolol increases expression ISO RGD:731014 6480464 Metoprolol results in increased expression of CCN2 mRNA CTD PMID:22888001 metoprolol increases expression EXP 6480464 Metoprolol results in increased expression of CCN2 mRNA CTD PMID:22888001 mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of CCN2 mRNA CTD PMID:25972201 mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of CCN2 mRNA CTD PMID:16809437 Muraglitazar decreases expression EXP 6480464 muraglitazar results in decreased expression of CCN2 mRNA CTD PMID:21515302 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] CTD PMID:17270171 N-methyl-4-phenylpyridinium decreases expression ISO RGD:731013 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of CCN2 mRNA CTD PMID:24810058 N-methyl-N-nitrosourea decreases expression EXP 6480464 Methylnitrosourea results in decreased expression of CCN2 mRNA CTD PMID:16525678 N-methylformamide increases expression ISO RGD:731014 6480464 methylformamide analog results in increased expression of CCN2 mRNA, methylformamide results in increased expression of CCN2 mRNA CTD PMID:17040096 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN2 mRNA CTD PMID:18164116 N-nitrosodiethylamine multiple interactions ISO RGD:731014 6480464 [1 more ... CTD PMID:21391223 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of CCN2 mRNA CTD PMID:19638242 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of CCN2 mRNA, Dimethylnitrosamine results in increased expression of CCN2 protein CTD PMID:15067225 more ... N-nitrosodimethylamine multiple interactions EXP 6480464 CCN2 protein affects the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA], CCN2 protein affects the reaction [Dimethylnitrosamine results in increased expression of TGFB1 protein] CTD PMID:17344905 nicotine increases expression EXP 6480464 Nicotine results in increased expression of CCN2 protein CTD PMID:22691361 nitric oxide multiple interactions ISO RGD:731014 6480464 [[[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] which results in increased abundance of Nitric Oxide] which results in decreased expression of CCN2 protein CTD PMID:24412304 nitrofen multiple interactions EXP 6480464 Tretinoin inhibits the reaction [nitrofen results in decreased expression of CCN2 mRNA], Tretinoin inhibits the reaction [nitrofen results in decreased expression of CCN2 protein] CTD PMID:21258935 nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of CCN2 mRNA, nitrofen results in decreased expression of CCN2 protein CTD PMID:20939759 more ... NSC 23766 multiple interactions ISO RGD:731014 6480464 NSC 23766 inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA] CTD PMID:28710503 O-methyleugenol decreases expression ISO RGD:731013 6480464 methyleugenol results in decreased expression of CCN2 mRNA CTD PMID:32234424 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of CCN2 mRNA CTD PMID:19717638 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of CCN2 mRNA CTD PMID:23358140 olaparib multiple interactions ISO RGD:731014 6480464 olaparib inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCN2 mRNA] CTD PMID:27984176 oxaliplatin increases expression EXP 6480464 Oxaliplatin results in increased expression of CCN2 mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [Oxaliplatin co-treated with Topotecan] results in increased expression of CCN2 mRNA CTD PMID:25729387 p-chloromercuribenzoic acid increases expression ISO RGD:731013 6480464 p-Chloromercuribenzoic Acid results in increased expression of CCN2 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:731013 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCN2 mRNA CTD PMID:27188386 paclitaxel multiple interactions ISO RGD:731013 6480464 [Cisplatin co-treated with Paclitaxel] affects the expression of CCN2 mRNA CTD PMID:20705681 Paeonol multiple interactions EXP 6480464 paeonol inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA] CTD PMID:31307187 paracetamol increases expression ISO RGD:731014 6480464 Acetaminophen results in increased expression of CCN2 mRNA CTD PMID:11264010 more ... paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of CCN2 mRNA CTD PMID:33387578 paracetamol affects expression ISO RGD:731013 6480464 Acetaminophen affects the expression of CCN2 mRNA CTD PMID:25458485 paracetamol decreases expression ISO RGD:731013 6480464 Acetaminophen results in decreased expression of CCN2 mRNA CTD PMID:22230336 paracetamol increases expression ISO RGD:731013 6480464 Acetaminophen results in increased expression of CCN2 mRNA CTD PMID:21420995 paracetamol multiple interactions ISO RGD:731014 6480464 NOS2 protein inhibits the reaction [Acetaminophen results in increased expression of CCN2 mRNA] more ... CTD PMID:12392966 more ... paracetamol affects expression ISO RGD:731014 6480464 Acetaminophen affects the expression of CCN2 mRNA CTD PMID:15606129 , PMID:17562736 paraquat multiple interactions ISO RGD:731013 6480464 [CCN2 protein co-treated with Paraquat] affects the expression of MMP2 mRNA more ... CTD PMID:15728566 more ... paraquat increases secretion EXP 6480464 Paraquat results in increased secretion of CCN2 protein CTD PMID:33000210 paraquat increases expression ISO RGD:731013 6480464 Paraquat results in increased expression of CCN2 mRNA, Paraquat results in increased expression of CCN2 protein CTD PMID:15728566 more ... paraquat multiple interactions EXP 6480464 LY2109761 inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA] more ... CTD PMID:23433149 , PMID:33000210 paraquat increases expression EXP 6480464 Paraquat results in increased expression of CCN2 mRNA, Paraquat results in increased expression of CCN2 protein CTD PMID:23433149 more ... paraquat multiple interactions ISO RGD:731014 6480464 ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA] more ... CTD PMID:25945502 more ... paraquat increases expression ISO RGD:731014 6480464 Paraquat results in increased expression of CCN2 mRNA, Paraquat results in increased expression of CCN2 protein CTD PMID:12595580 more ... parathion increases methylation ISO RGD:731013 6480464 Parathion results in increased methylation of CCN2 promoter CTD PMID:22847954 pentane-2,3-dione increases expression EXP 6480464 2, 3-pentanedione results in increased expression of CCN2 mRNA CTD PMID:25710175 Pentoxifylline decreases expression EXP 6480464 Pentoxifylline results in decreased expression of CCN2 mRNA CTD PMID:11788567 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of CCN2 mRNA CTD PMID:21251948 perfluorooctane-1-sulfonic acid increases expression ISO RGD:731013 6480464 perfluorooctane sulfonic acid results in increased expression of CCN2 mRNA CTD PMID:27153767 perfluorooctanoic acid decreases expression ISO RGD:731013 6480464 perfluorooctanoic acid results in decreased expression of CCN2 protein CTD PMID:26879310 perfluorooctanoic acid increases expression ISO RGD:731013 6480464 perfluorooctanoic acid results in increased expression of CCN2 protein CTD PMID:35346789 phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of CCN2 mRNA CTD PMID:31324951 phenobarbital increases expression ISO RGD:731014 6480464 Phenobarbital results in increased expression of CCN2 mRNA CTD PMID:19270015 phenobarbital decreases expression ISO RGD:731013 6480464 Phenobarbital results in decreased expression of CCN2 mRNA CTD PMID:19084549 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of CCN2 mRNA, Phenylephrine results in increased expression of CCN2 protein CTD PMID:15276029 phenylmercury acetate increases expression ISO RGD:731013 6480464 Phenylmercuric Acetate results in increased expression of CCN2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:731013 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCN2 mRNA CTD PMID:27188386 phloroglucinol multiple interactions ISO RGD:731013 6480464 Phloroglucinol analog inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:26054450 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:731014 6480464 [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCN2 mRNA CTD PMID:31904401 phosphane increases expression EXP 6480464 phosphine results in increased expression of CTGF mRNA CTD PMID:34427094 pioglitazone multiple interactions ISO RGD:731013 6480464 [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCN2 mRNA, Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of CCN2 mRNA] CTD PMID:20847119 pioglitazone multiple interactions EXP 6480464 Pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] CTD PMID:16484506 pirfenidone multiple interactions ISO RGD:731014 6480464 pirfenidone inhibits the reaction [Bleomycin results in increased expression of CCN2 protein] CTD PMID:35654123 pirinixic acid multiple interactions ISO RGD:731013 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CCN2 mRNA, pirinixic acid inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:19429239 , PMID:19710929 pirinixic acid increases expression ISO RGD:731014 6480464 pirinixic acid results in increased expression of CCN2 mRNA CTD PMID:18301758 , PMID:23811191 piroxicam decreases expression ISO RGD:731013 6480464 Piroxicam results in decreased expression of CCN2 mRNA CTD PMID:21858171 platycodin D decreases expression EXP 6480464 platycodin D results in decreased expression of CCN2 protein CTD PMID:29595072 potassium cyanide increases expression ISO RGD:731014 6480464 Potassium Cyanide results in increased expression of CCN2 mRNA CTD PMID:33914522 prednisolone increases expression ISO RGD:731013 6480464 Prednisolone results in increased expression of CCN2 mRNA CTD PMID:19192274 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:731014 6480464 Pregnenolone Carbonitrile results in increased expression of CCN2 mRNA CTD PMID:28903501 progesterone affects expression ISO RGD:731014 6480464 Progesterone affects the expression of CCN2 mRNA CTD PMID:17251523 progesterone increases expression ISO RGD:731014 6480464 Progesterone results in increased expression of CCN2 mRNA CTD PMID:22238285 progesterone increases abundance ISO RGD:731014 6480464 CCN2 gene mutant form results in increased abundance of Progesterone CTD PMID:21868453 progesterone multiple interactions ISO RGD:731014 6480464 [CCN2 gene mutant form results in increased abundance of Progesterone] which results in increased expression of CASP3 mRNA CTD PMID:21868453 prostaglandin E2 multiple interactions ISO RGD:731014 6480464 [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA] more ... CTD PMID:28434932 puerarin multiple interactions ISO RGD:731014 6480464 puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of CCN2 mRNA], puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] CTD PMID:27318789 , PMID:31273855 quercetin decreases expression ISO RGD:731013 6480464 Quercetin results in decreased expression of CCN2 mRNA CTD PMID:21632981 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] more ... CTD PMID:15573758 more ... quercetin multiple interactions ISO RGD:731014 6480464 Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCN2 mRNA] CTD PMID:22915297 ramipril multiple interactions EXP 6480464 [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein CTD PMID:31062909 resveratrol affects expression EXP 6480464 Resveratrol affects the expression of CCN2 mRNA CTD PMID:17875610 resveratrol multiple interactions ISO RGD:731013 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of CCN2 mRNA CTD PMID:23557933 resveratrol decreases expression ISO RGD:731013 6480464 Resveratrol results in decreased expression of CCN2 mRNA CTD PMID:23224687 resveratrol multiple interactions EXP 6480464 [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein more ... CTD PMID:26891083 , PMID:31062909 rofecoxib multiple interactions ISO RGD:731014 6480464 rofecoxib inhibits the reaction [Carbon Tetrachloride results in increased expression of CCN2 protein] CTD PMID:17565644 rosmarinic acid multiple interactions EXP 6480464 rosmarinic acid inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:28789951 rosmarinic acid decreases expression EXP 6480464 rosmarinic acid results in decreased expression of CCN2 mRNA CTD PMID:28789951 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of CCN2 mRNA CTD PMID:28374803 rutin multiple interactions EXP 6480464 Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA], Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein] CTD PMID:24117263 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO RGD:731013 6480464 S-(1, 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CCN2 mRNA] CTD PMID:35811015 saralasin multiple interactions ISO RGD:731013 6480464 Saralasin inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA], Saralasin inhibits the reaction [Paraquat results in increased expression of CCN2 protein] CTD PMID:20035857 SB 203580 multiple interactions ISO RGD:731013 6480464 SB 203580 analog inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein], SB 203580 inhibits the reaction [Glucose results in increased expression of CCN2 protein] CTD PMID:19369054 , PMID:26054450 SB 203580 decreases expression ISO RGD:731013 6480464 SB 203580 results in decreased expression of CCN2 protein CTD PMID:20864298 SB 431542 multiple interactions ISO RGD:731013 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 serpentine asbestos increases expression ISO RGD:731014 6480464 Asbestos, Serpentine results in increased expression of CCN2 CTD PMID:19817698 serpentine asbestos multiple interactions ISO RGD:731014 6480464 TGFB1 protein affects the reaction [Asbestos, Serpentine results in increased expression of CCN2] CTD PMID:19817698 sildenafil citrate multiple interactions ISO RGD:731014 6480464 PRKG1 protein promotes the reaction [Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of CCN2 mRNA]], Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of CCN2 mRNA] CTD PMID:25139994 silicon dioxide increases expression ISO RGD:731013 6480464 Silicon Dioxide results in increased expression of CCN2 mRNA CTD PMID:25351596 , PMID:27095093 silicon dioxide increases expression ISO RGD:731014 6480464 Silicon Dioxide results in increased expression of CTGF protein CTD PMID:33428986 silicon dioxide multiple interactions ISO RGD:731014 6480464 ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of CTGF protein] CTD PMID:33428986 simvastatin multiple interactions ISO RGD:731013 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]] more ... CTD PMID:15298857 , PMID:15677772 simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of CCN2 mRNA, Simvastatin results in decreased expression of CCN2 protein CTD PMID:15200425 more ... simvastatin multiple interactions EXP 6480464 Simvastatin inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein] CTD PMID:15200425 simvastatin multiple interactions ISO RGD:731014 6480464 Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 mRNA], Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein] CTD PMID:19080365 sirolimus increases expression EXP 6480464 Sirolimus results in increased expression of CCN2 mRNA CTD PMID:21865292 sodium arsenite affects expression ISO RGD:731014 6480464 sodium arsenite affects the expression of CCN2 mRNA CTD PMID:16507464 sodium arsenite decreases expression ISO RGD:731013 6480464 sodium arsenite results in decreased expression of CCN2 mRNA CTD PMID:34032870 sodium arsenite multiple interactions ISO RGD:731014 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Dietary Fats] results in increased expression of CCN2 protein, [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CCN2 protein CTD PMID:31238026 sodium arsenite multiple interactions EXP 6480464 candesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of CCN2 protein] CTD PMID:27889505 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of CCN2 mRNA, sodium arsenite results in increased expression of CCN2 protein CTD PMID:27889505 , PMID:32593899 sodium arsenite increases expression ISO RGD:731013 6480464 sodium arsenite results in increased expression of CCN2 mRNA CTD PMID:12377979 , PMID:25879800 sodium dodecyl sulfate decreases expression ISO RGD:731013 6480464 Sodium Dodecyl Sulfate results in decreased expression of CCN2 mRNA CTD PMID:25377654 sodium dodecyl sulfate increases expression ISO RGD:731013 6480464 Sodium Dodecyl Sulfate results in increased expression of CCN2 mRNA CTD PMID:31734321 sodium tungstate decreases expression ISO RGD:731013 6480464 sodium tungstate(VI) results in decreased expression of CCN2 mRNA CTD PMID:26164860 sorafenib decreases expression ISO RGD:731014 6480464 Sorafenib results in decreased expression of CCN2 mRNA CTD PMID:21360571 sphingosine 1-phosphate increases expression ISO RGD:731014 6480464 sphingosine 1-phosphate results in increased expression of CCN2 mRNA CTD PMID:25690654 sphingosine 1-phosphate increases expression ISO RGD:731013 6480464 sphingosine 1-phosphate results in increased expression of CCN2 mRNA CTD PMID:25690654 spironolactone multiple interactions EXP 6480464 Spironolactone inhibits the reaction [Aldosterone results in increased expression of CCN2 protein] CTD PMID:17278980 stattic multiple interactions ISO RGD:731013 6480464 stattic inhibits the reaction [IL6 protein results in increased expression of CCN2 mRNA] CTD PMID:25740948 stattic multiple interactions ISO RGD:731014 6480464 stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA] CTD PMID:25740948 streptozocin increases expression ISO RGD:731014 6480464 Streptozocin results in increased expression of CCN2, Streptozocin results in increased expression of CCN2 protein CTD PMID:19657322 , PMID:24967692 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of CCN2 mRNA, Streptozocin results in increased expression of CCN2 protein CTD PMID:10026205 more ... streptozocin multiple interactions ISO RGD:731014 6480464 [Dietary Fats co-treated with Streptozocin] promotes the reaction [KLF15 gene mutant form results in increased expression of CCN2 protein] more ... CTD PMID:24707343 more ... streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein more ... CTD PMID:14586741 more ... succimer multiple interactions ISO RGD:731013 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of CCN2 mRNA CTD PMID:26378955 sulforaphane multiple interactions ISO RGD:731014 6480464 [NFE2L2 protein affects the susceptibility to sulforaphane] affects the reaction [Oxygen deficiency results in increased expression of CCN2 protein] more ... CTD PMID:24707343 more ... sulindac sulfide decreases expression ISO RGD:731013 6480464 sulindac sulfide results in decreased expression of CCN2 mRNA CTD PMID:12734198 sulindac sulfide increases expression ISO RGD:731013 6480464 sulindac sulfide results in increased expression of CCN2 mRNA CTD PMID:16184548 sunitinib multiple interactions EXP 6480464 Carnitine inhibits the reaction [Sunitinib results in increased expression of CCN2 mRNA], SN50 peptide inhibits the reaction [Sunitinib results in increased expression of CCN2 mRNA] CTD PMID:26581635 sunitinib increases expression EXP 6480464 Sunitinib results in increased expression of CCN2 mRNA CTD PMID:26581635 tacrolimus hydrate multiple interactions EXP 6480464 Tacrolimus inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA], Tacrolimus inhibits the reaction [Paraquat results in increased secretion of CCN2 protein] CTD PMID:33000210 tamoxifen increases expression ISO RGD:731014 6480464 Tamoxifen results in increased expression of CCN2 mRNA CTD PMID:25123088 tamoxifen affects expression ISO RGD:731014 6480464 Tamoxifen affects the expression of CCN2 mRNA CTD PMID:20937368 tauroursodeoxycholic acid decreases expression EXP 6480464 ursodoxicoltaurine results in decreased expression of CCN2 mRNA CTD PMID:15885361 tebufenpyrad increases expression ISO RGD:731013 6480464 4-chloro-N-((4-(1, 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of CCN2 mRNA CTD PMID:33512557 temozolomide increases expression ISO RGD:731013 6480464 Temozolomide results in increased expression of CCN2 mRNA CTD PMID:31758290 terbufos increases methylation ISO RGD:731013 6480464 terbufos results in increased methylation of CCN2 promoter CTD PMID:22847954 tert-butyl hydroperoxide multiple interactions ISO RGD:731013 6480464 [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCN2 mRNA more ... CTD PMID:20847119 tert-butyl hydroperoxide affects expression ISO RGD:731013 6480464 tert-Butylhydroperoxide affects the expression of CCN2 mRNA CTD PMID:23410634 tert-butyl hydroperoxide decreases expression ISO RGD:731013 6480464 tert-Butylhydroperoxide results in decreased expression of CCN2 mRNA CTD PMID:20847119 testosterone increases expression ISO RGD:731014 6480464 Testosterone results in increased expression of CCN2 mRNA CTD PMID:15788153 testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CCN2 mRNA CTD PMID:32741896 tetrachloromethane multiple interactions ISO RGD:731014 6480464 ADIPOQ protein affects the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] more ... CTD PMID:14724832 more ... tetrachloromethane multiple interactions EXP 6480464 CCN2 affects the reaction [Carbon Tetrachloride results in increased activity of TGFB1 protein] more ... CTD PMID:16484506 more ... tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of CCN2 mRNA, Carbon Tetrachloride results in increased expression of CCN2 protein CTD PMID:16420518 more ... tetrachloromethane increases expression ISO RGD:731014 6480464 Carbon Tetrachloride results in increased expression of CCN2 mRNA, Carbon Tetrachloride results in increased expression of CCN2 protein CTD PMID:14724832 more ... tetracycline increases expression ISO RGD:731014 6480464 Tetracycline results in increased expression of CCN2 mRNA CTD PMID:16917069 tetramethylpyrazine multiple interactions ISO RGD:731014 6480464 tetramethylpyrazine inhibits the reaction [Paraquat results in increased expression of CCN2 protein] CTD PMID:30744607 thioacetamide multiple interactions ISO RGD:731014 6480464 [Ethanol co-treated with Thioacetamide] results in increased expression of CCN2 mRNA, TGFBR1 protein promotes the reaction [Thioacetamide results in increased expression of CCN2 mRNA] CTD PMID:21863215 , PMID:28560358 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of CCN2 mRNA, Thioacetamide results in increased expression of CCN2 protein CTD PMID:22899499 , PMID:34492290 thioacetamide multiple interactions EXP 6480464 Coffee inhibits the reaction [Thioacetamide results in increased expression of CCN2 protein] CTD PMID:22899499 thioacetamide increases expression ISO RGD:731014 6480464 Thioacetamide results in increased expression of CCN2 mRNA CTD PMID:28560358 titanium dioxide increases expression ISO RGD:731014 6480464 titanium dioxide results in increased expression of CCN2 mRNA CTD PMID:27760801 topotecan multiple interactions EXP 6480464 [Oxaliplatin co-treated with Topotecan] results in increased expression of CCN2 mRNA CTD PMID:25729387 topotecan increases expression EXP 6480464 Topotecan results in increased expression of CCN2 mRNA CTD PMID:25729387 triadimefon decreases expression ISO RGD:731013 6480464 triadimefon results in decreased expression of CTGF mRNA CTD PMID:26705709 triamcinolone acetonide multiple interactions ISO RGD:731013 6480464 Triamcinolone Acetonide promotes the reaction [Paraquat results in increased expression of CCN2 mRNA] CTD PMID:15728566 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of CCN2 mRNA CTD PMID:33387578 trichostatin A increases expression ISO RGD:731013 6480464 trichostatin A results in increased expression of CCN2 mRNA, trichostatin A results in increased expression of CTGF mRNA CTD PMID:19606018 , PMID:26705709 triclosan affects expression ISO RGD:731013 6480464 Triclosan affects the expression of CCN2 mRNA CTD PMID:31714634 triphenyl phosphate affects expression EXP 6480464 triphenyl phosphate affects the expression of CCN2 mRNA CTD PMID:30589522 triptonide increases expression ISO RGD:731014 6480464 triptonide results in increased expression of CCN2 mRNA CTD PMID:33045310 troglitazone multiple interactions ISO RGD:731013 6480464 [Troglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCN2 mRNA more ... CTD PMID:17056281 more ... troglitazone decreases expression ISO RGD:731013 6480464 Troglitazone results in decreased expression of CCN2 mRNA CTD PMID:25572481 troglitazone increases expression ISO RGD:731013 6480464 Troglitazone results in increased expression of CCN2 mRNA CTD PMID:19140230 urethane increases expression ISO RGD:731013 6480464 Urethane results in increased expression of CCN2 mRNA CTD PMID:28818685 ursodeoxycholic acid decreases expression EXP 6480464 Ursodeoxycholic Acid results in decreased expression of CCN2 mRNA CTD PMID:15885361 valproic acid affects expression ISO RGD:731013 6480464 Valproic Acid affects the expression of CCN2 mRNA CTD PMID:25979313 , PMID:26072468 valproic acid decreases methylation ISO RGD:731013 6480464 Valproic Acid results in decreased methylation of CCN2 gene CTD PMID:29501571 valproic acid increases expression ISO RGD:731013 6480464 Valproic Acid results in increased expression of CCN2 mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO RGD:731014 6480464 Valproic Acid affects the expression of CCN2 mRNA CTD PMID:17292431 , PMID:26072468 valproic acid decreases expression ISO RGD:731013 6480464 Valproic Acid results in decreased expression of CCN2 mRNA CTD PMID:24935251 vanillin decreases expression ISO RGD:731013 6480464 vanillin results in decreased expression of CCN2 mRNA CTD PMID:17178418 verteporfin decreases expression ISO RGD:731013 6480464 Verteporfin results in decreased expression of CCN2 mRNA CTD PMID:29725256 verteporfin multiple interactions ISO RGD:731013 6480464 Verteporfin inhibits the reaction [YAP1 protein results in increased expression of CCN2 mRNA] CTD PMID:29725256 vincaleukoblastine affects response to substance ISO RGD:731013 6480464 CCN2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of CCN2 mRNA CTD PMID:19015723 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of CCN2 mRNA CTD PMID:23034163 vincristine decreases response to substance ISO RGD:731013 6480464 CCN2 mRNA results in decreased susceptibility to Vincristine CTD PMID:24154679 vitamin D multiple interactions ISO RGD:731014 6480464 Vitamin D inhibits the reaction [Ethanol results in increased expression of CCN2 mRNA], Vitamin D inhibits the reaction [Ethanol results in increased expression of CCN2 protein] CTD PMID:19280452 vorinostat increases expression ISO RGD:731013 6480464 Vorinostat results in increased expression of CCN2 mRNA CTD PMID:27188386 Y-27632 multiple interactions EXP 6480464 Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein] CTD PMID:15200425 zinc atom multiple interactions ISO RGD:731013 6480464 Zinc inhibits the reaction [Glucose results in increased expression of CCN2 protein] CTD PMID:19369054 zinc atom multiple interactions ISO RGD:731014 6480464 Zinc inhibits the reaction [Dietary Fats results in increased expression of CCN2 protein] CTD PMID:27370414 zinc atom multiple interactions EXP 6480464 Zinc inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] CTD PMID:19369054 zinc(0) multiple interactions ISO RGD:731013 6480464 Zinc inhibits the reaction [Glucose results in increased expression of CCN2 protein] CTD PMID:19369054 zinc(0) multiple interactions EXP 6480464 Zinc inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] CTD PMID:19369054 zinc(0) multiple interactions ISO RGD:731014 6480464 Zinc inhibits the reaction [Dietary Fats results in increased expression of CCN2 protein] CTD PMID:27370414
