Bax (BCL2 associated X, apoptosis regulator) - Rat Genome Database

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Gene: Bax (BCL2 associated X, apoptosis regulator) Rattus norvegicus
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Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
RGD ID: 2192
Description: Enables BH domain binding activity; heat shock protein binding activity; and protein-folding chaperone binding activity. Involved in several processes, including mitochondrion organization; response to anesthetic; and response to ischemia. Located in cytosol; mitochondrial outer membrane; and perinuclear region of cytoplasm. Used to study brain glioma; endometriosis; morphine dependence; and pre-malignant neoplasm. Biomarker of several diseases, including artery disease (multiple); brain disease (multiple); heart disease (multiple); lung disease (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; ataxia telangiectasia; colon adenocarcinoma; and colorectal cancer. Orthologous to human BAX (BCL2 associated X, apoptosis regulator); PARTICIPATES IN intrinsic apoptotic pathway; ceramide signaling pathway; syndecan signaling pathway; INTERACTS WITH (+)-catechin; (+)-pilocarpine; (+)-sesamin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: apoptosis regulator BAX; Bcl2-associated X protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Bax-ps2  
Allele / Splice: Bax_v1   Bax_v2  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,076,472 - 105,081,906 (-)NCBIGRCr8
mRatBN7.2195,940,001 - 95,945,407 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,938,808 - 95,945,368 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,325,431 - 101,330,837 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,798,107 - 109,803,513 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,088,504 - 103,093,910 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,451,801 - 101,457,207 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,451,802 - 101,457,207 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,530,747 - 102,536,153 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,933,023 - 95,938,176 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,011,133 - 96,016,287 (-)NCBI
Celera190,195,913 - 90,201,319 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model