Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Gpat4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GPAT4 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | increases expression | ISO | Gpat4 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of GPAT4 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | GPAT4 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GPAT4 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Gpat4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GPAT4 mRNA | CTD | PMID:28213091 and PMID:28238261 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Gpat4 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of GPAT4 mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to GPAT4 gene] | CTD | PMID:16214954 and PMID:28213091 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Gpat4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GPAT4 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GPAT4 mRNA | CTD | PMID:21215274 and PMID:33387578 | 2,4,6-trinitrotoluene | affects expression | EXP | | 6480464 | Trinitrotoluene affects the expression of GPAT4 mRNA | CTD | PMID:21346803 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of GPAT4 mRNA | CTD | PMID:21346803 | 3,3',4,4'-tetrachlorobiphenyl | multiple interactions | ISO | Gpat4 (Mus musculus) | 6480464 | 3 more ... | CTD | PMID:19467301 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Gpat4 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of GPAT4 mRNA | CTD | PMID:20188158 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | GPAT4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GPAT4 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Gpat4 (Mus musculus) | 6480464 | bisphenol S affects the methylation of GPAT4 gene | CTD | PMID:31683443 | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of GPAT4 mRNA | CTD | PMID:21346803 | aflatoxin B1 | increases expression | ISO | GPAT4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of GPAT4 mRNA | CTD | PMID:22100608 | antirheumatic drug | decreases expression | ISO | GPAT4 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of GPAT4 mRNA | CTD | PMID:24449571 | aristolochic acid A | increases expression | ISO | GPAT4 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of GPAT4 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | GPAT4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of GPAT4 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | GPAT4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of GPAT4 gene | CTD | PMID:25304211 | benzo[a]pyrene | decreases expression | ISO | Gpat4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of GPAT4 mRNA | CTD | PMID:23735875 | benzo[a]pyrene | decreases methylation | ISO | GPAT4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of GPAT4 3' UTR and Benzo(a)pyrene results in decreased methylation of GPAT4 promoter | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | GPAT4 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of GPAT4 intron | CTD | PMID:30157460 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of GPAT4 mRNA | CTD | PMID:26496021 | bisphenol A | decreases methylation | ISO | GPAT4 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of GPAT4 gene | CTD | PMID:31601247 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of GPAT4 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GPAT4 mRNA | CTD | PMID:25748669 more ... | bisphenol F | multiple interactions | ISO | GPAT4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GPAT4 mRNA | CTD | PMID:28628672 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of GPAT4 promoter | CTD | PMID:22457795 | CGP 52608 | multiple interactions | ISO | GPAT4 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GPAT4 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases response to substance | ISO | GPAT4 (Homo sapiens) | 6480464 | GPAT4 gene mutant form results in decreased susceptibility to Chlorpyrifos | CTD | PMID:26299976 | coumestrol | multiple interactions | ISO | GPAT4 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of GPAT4 mRNA | CTD | PMID:23640034 | dexamethasone | multiple interactions | ISO | GPAT4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GPAT4 mRNA | CTD | PMID:28628672 | Enterolactone | multiple interactions | ISO | GPAT4 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GPAT4 mRNA | CTD | PMID:19167446 | ethanol | multiple interactions | ISO | Gpat4 (Mus musculus) | 6480464 | [Carbon Tetrachloride co-treated with Ethanol] results in decreased expression of GPAT4 mRNA | CTD | PMID:30517762 | ethanol | affects splicing | ISO | Gpat4 (Mus musculus) | 6480464 | Ethanol affects the splicing of GPAT4 mRNA | CTD | PMID:30319688 | farnesol | multiple interactions | ISO | GPAT4 (Homo sapiens) | 6480464 | [Farnesol analog co-treated with Oleic Acid] results in increased expression of GPAT4 mRNA | CTD | PMID:30611723 | fenthion | decreases expression | ISO | Gpat4 (Mus musculus) | 6480464 | Fenthion results in decreased expression of GPAT4 mRNA | CTD | PMID:34813904 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of GPAT4 mRNA | CTD | PMID:24136188 | folic acid | increases expression | ISO | Gpat4 (Mus musculus) | 6480464 | Folic Acid results in increased expression of GPAT4 mRNA | CTD | PMID:25629700 | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of GPAT4 mRNA | CTD | PMID:25539665 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of GPAT4 mRNA | CTD | PMID:33387578 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of GPAT4 mRNA | CTD | PMID:24136188 | GW 4064 | multiple interactions | ISO | GPAT4 (Homo sapiens) | 6480464 | [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT4 mRNA | CTD | PMID:30611723 | indometacin | multiple interactions | ISO | GPAT4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GPAT4 mRNA | CTD | PMID:28628672 | indometacin | increases expression | EXP | | 6480464 | Indomethacin results in increased expression of GPAT4 mRNA | CTD | PMID:36868495 | lead diacetate | increases expression | ISO | Gpat4 (Mus musculus) | 6480464 | lead acetate results in increased expression of GPAT4 mRNA | CTD | PMID:20542052 | methapyrilene | increases methylation | ISO | GPAT4 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of GPAT4 intron | CTD | PMID:30157460 | methidathion | decreases expression | ISO | Gpat4 (Mus musculus) | 6480464 | methidathion results in decreased expression of GPAT4 mRNA | CTD | PMID:34813904 | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of GPAT4 gene | CTD | PMID:33148267 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of GPAT4 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of GPAT4 mRNA | CTD | PMID:24136188 | oleic acid | multiple interactions | ISO | GPAT4 (Homo sapiens) | 6480464 | [Farnesol analog co-treated with Oleic Acid] results in increased expression of GPAT4 mRNA and [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT4 mRNA | CTD | PMID:30611723 | paracetamol | increases expression | ISO | GPAT4 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of GPAT4 mRNA | CTD | PMID:22230336 | parathion | increases expression | ISO | Gpat4 (Mus musculus) | 6480464 | Parathion results in increased expression of GPAT4 mRNA | CTD | PMID:34813904 | pentachlorophenol | increases expression | ISO | Gpat4 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of GPAT4 mRNA | CTD | PMID:23892564 | perfluorohexanesulfonic acid | decreases expression | ISO | Gpat4 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of GPAT4 mRNA | CTD | PMID:37995155 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Gpat4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GPAT4 mRNA | CTD | PMID:36331819 | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of GPAT4 gene | CTD | PMID:33148267 | pirinixic acid | increases expression | ISO | Gpat4 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of GPAT4 mRNA | CTD | PMID:18301758 and PMID:23811191 | resveratrol | multiple interactions | ISO | GPAT4 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of GPAT4 mRNA | CTD | PMID:19167446 | testosterone | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of GPAT4 mRNA | CTD | PMID:26496021 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of GPAT4 mRNA | CTD | PMID:16239168 | tetrachloromethane | multiple interactions | ISO | Gpat4 (Mus musculus) | 6480464 | [Carbon Tetrachloride co-treated with Ethanol] results in decreased expression of GPAT4 mRNA | CTD | PMID:30517762 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of GPAT4 mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | Gpat4 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of GPAT4 mRNA | CTD | PMID:23557971 | urethane | increases expression | ISO | GPAT4 (Homo sapiens) | 6480464 | Urethane results in increased expression of GPAT4 mRNA | CTD | PMID:28818685 | |