Gene: Cdk1 (cyclin-dependent kinase 1) Rattus norvegicus
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Symbol: Cdk1
Name: cyclin-dependent kinase 1
Description: ENCODES a protein that exhibits cyclin binding; cyclin-dependent protein serine/threonine kinase activity; histone kinase activity; INVOLVED IN animal organ regeneration; cell aging; cellular response to hydrogen peroxide; PARTICIPATES IN cell cycle pathway, mitotic; G1/S transition pathway; G2/M checkpoint pathway; ASSOCIATED WITH hepatocellular carcinoma; Spinal Cord Injuries; Thyroid Neoplasms; FOUND IN cytoplasm; nucleus; centrosome (ortholog); INTERACTS WITH (+)-catechin; (+)-pilocarpine; (R)-mevalonic acid
AGR Description: Exhibits cyclin binding activity, cyclin-dependent protein serine/threonine kinase activity, and histone kinase activity; involved in several processes, including Golgi disassembly, animal organ development, and positive regulation of macromolecule metabolic process; localizes to the cytoplasm and nucleus; predicted to colocalize with the mitochondrial matrix; biomarker of hepatocellular carcinoma; orthologous to human CDK1 (cyclin dependent kinase 1).
Merged Description: Exhibits cyclin binding activity, cyclin-dependent protein serine/threonine kinase activity, and histone kinase activity; involved in several processes, including Golgi disassembly, animal organ development, and positive regulation of macromolecule metabolic process; localizes to the cytoplasm and nucleus; predicted to colocalize with the mitochondrial matrix; biomarker of hepatocellular carcinoma; orthologous to human CDK1 (cyclin dependent kinase 1); PARTICIPATES IN cell cycle pathway, mitotic; G1/S transition pathway; G2/M checkpoint pathway; INTERACTS WITH (+)-catechin; (+)-pilocarpine; (R)-mevalonic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cdc2; Cdc2a; cell division control protein 2 homolog; cell division cycle 2; cell division cycle 2 homolog A; cell division cycle 2 homolog A (S. pombe); cell division cycle 2, G1 to S and G2 to M; Cell division cycle control protein 2; cell division protein kinase 1; p34 protein kinase
Orthologs:
Homo sapiens (human) : CDK1 (cyclin dependent kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Cdk1 (cyclin-dependent kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk1 (cyclin dependent kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK1 (cyclin dependent kinase 1)
Canis lupus familiaris (dog) : CDK1 (cyclin dependent kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk1 (cyclin dependent kinase 1)
Sus scrofa (pig) : CDK1 (cyclin dependent kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02020,576,341 - 20,591,510 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02022,694,883 - 22,709,860 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42020,018,044 - 20,044,030 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12020,031,843 - 20,057,830 (+)NCBI
Celera2020,642,946 - 20,658,475 (+)NCBICelera
Cytogenetic Map20p11NCBI
RH 3.4 Map20252.37RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cdk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2319
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.