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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2319
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdk1
Name: cyclin-dependent kinase 1
Acc ID: CHEBI:69478
Term: cannabidiol
Definition: An cannabinoid that is cyclohexene which is substituted by a methyl group at position 1, a 2,6-dihydroxy-4-pentylphenyl group at position 3, and a prop-1-en-2-yl group at position 4.
Chemical ID: MESH:D002185
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdk1affects expressionISOCDK1 (Homo sapiens)6480464CTDCannabidiol affects the expression of CDK1 proteinPMID:26504004
Cdk1decreases expressionISOCDK1 (Homo sapiens)6480464CTDCannabidiol results in decreased expression of CDK1 mRNAPMID:36519830
Cdk1multiple interactionsISOCDK1 (Homo sapiens)6480464CTD[Cannabidiol co-treated with moringin] results in increased expression of CDK1 mRNA; tanespimycin affects the reaction [Cannabidiol affects the expression of CDK1 protein]; VER 155008 affects the reaction [Cannabidiol affects the expression of CDK1 protein]PMID:26504004 PMID:30096889
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