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Gene: Cdk1 (cyclin-dependent kinase 1) Mus musculus
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Symbol: Cdk1
Name: cyclin-dependent kinase 1
Description: Exhibits Hsp70 protein binding activity; chromatin binding activity; and cyclin-dependent protein serine/threonine kinase activity. Involved in several processes, including mitotic G2 DNA damage checkpoint; mitotic cell cycle phase transition; and protein phosphorylation. Colocalizes with the mitochondrial matrix. Human ortholog(s) of this gene implicated in breast cancer; cervical cancer; and urinary bladder cancer. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human CDK1 (cyclin dependent kinase 1); PARTICIPATES IN cell cycle pathway, mitotic; p53 signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cdc2; Cdc2a; cell cycle p34 CDC2 kinase protein; cell division control protein 2 homolog; cell division cycle 2 homolog A; cell division cycle control protein 2a; cell division protein kinase 1; p34 protein kinase; p34
Orthologs:
Homo sapiens (human) : CDK1 (cyclin dependent kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdk1 (cyclin-dependent kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk1 (cyclin dependent kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK1 (cyclin dependent kinase 1)
Canis lupus familiaris (dog) : CDK1 (cyclin dependent kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk1 (cyclin dependent kinase 1)
Sus scrofa (pig) : CDK1 (cyclin dependent kinase 1)
more info ...
Related Pseudogenes: Gm18371   Gm49852  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381069,335,146 - 69,352,912 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371068,799,383 - 68,815,660 (-)NCBIGRCm37mm9NCBIm37
MGSCv361068,731,992 - 68,748,269 (-)NCBImm8
Celera1070,426,785 - 70,443,097 (-)NCBICelera
Cytogenetic Map10 B5.3NCBI
cM Map1036.07NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cdk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731890
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.