Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Smc2 (structural maintenance of chromosomes 2) Rattus norvegicus
Analyze
Symbol: Smc2
Name: structural maintenance of chromosomes 2
RGD ID: 1305227
Description: Predicted to have chromatin binding activity and single-stranded DNA binding activity. Predicted to be involved in chromosome condensation; kinetochore organization; and meiotic chromosome segregation. Predicted to localize to condensin core heterodimer; cytoplasm; and nuclear lumen. Orthologous to human SMC2 (structural maintenance of chromosomes 2); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CAP-E; CAPE; chromosome-associated protein E; LOC362519; SMC2 structural maintenance of chromosomes 2-like 1; SMC2 structural maintenance of chromosomes 2-like 1 (yeast); Smc2l1; structural maintenance of chromosomes protein 2
Orthologs:
Homo sapiens (human) : SMC2 (structural maintenance of chromosomes 2)  HGNC  Alliance
Mus musculus (house mouse) : Smc2 (structural maintenance of chromosomes 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smc2 (structural maintenance of chromosomes 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SMC2 (structural maintenance of chromosomes 2)
Canis lupus familiaris (dog) : SMC2 (structural maintenance of chromosomes 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smc2 (structural maintenance of chromosomes 2)
Sus scrofa (pig) : SMC2 (structural maintenance of chromosomes 2)
Chlorocebus sabaeus (African green monkey) : SMC2 (structural maintenance of chromosomes 2)
Heterocephalus glaber (naked mole-rat) : Smc2 (structural maintenance of chromosomes 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0568,717,509 - 68,764,080 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl568,717,519 - 68,763,850 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0573,151,967 - 73,198,538 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4569,561,142 - 69,607,373 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1569,566,160 - 69,612,480 (+)NCBI
Celera560,812,631 - 60,858,839 (-)NCBICelera
Cytogenetic Map5q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
  
More on Smc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305227
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.