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Gene: Hells (helicase, lymphoid specific) Rattus norvegicus
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Symbol: Hells
Name: helicase, lymphoid specific
Description: Predicted to have chromatin binding activity. Predicted to be involved in several processes, including DNA metabolic process; cellular response to leukemia inhibitory factor; and chromatin organization. Predicted to localize to the nucleus and pericentric heterochromatin. Human ortholog(s) of this gene implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 4. Orthologous to human HELLS (helicase, lymphoid specific); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC294071; similar to helicase, lymphoid specific; Tbc1d12; TBC1D12: TBC1 domain family, member 12
Orthologs:
Homo sapiens (human) : HELLS (helicase, lymphoid specific)  HGNC  Alliance
Mus musculus (house mouse) : Hells (helicase, lymphoid specific)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hells (helicase, lymphoid specific)
Pan paniscus (bonobo/pygmy chimpanzee) : HELLS (helicase, lymphoid specific)
Canis lupus familiaris (dog) : HELLS (helicase, lymphoid specific)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hells (helicase, lymphoid specific)
Sus scrofa (pig) : HELLS (helicase, lymphoid-specific)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01257,901,856 - 257,953,889 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01265,357,043 - 265,402,172 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,246,843 - 243,262,459 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1233,793,113 - 233,835,276 (+)NCBICelera
Cytogenetic Map1q53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Hells
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309820
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.