Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gsk3a (glycogen synthase kinase 3 alpha) Rattus norvegicus
Symbol: Gsk3a
Name: glycogen synthase kinase 3 alpha
RGD ID: 620351
Description: Exhibits protein kinase A catalytic subunit binding activity and protein serine/threonine kinase activity. Involved in several processes, including negative regulation of dendrite development; positive regulation of neuron apoptotic process; and protein phosphorylation. Localizes to cytoplasm and microtubule. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha); PARTICIPATES IN glycogen biosynthetic pathway; nuclear factor, erythroid 2 like 2 signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide.
Type: protein-coding
Also known as: FA; factor A; glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A
Homo sapiens (human) : GSK3A (glycogen synthase kinase 3 alpha)  HGNC  Alliance
Mus musculus (house mouse) : Gsk3a (glycogen synthase kinase 3 alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gsk3a (glycogen synthase kinase 3 alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : GSK3A (glycogen synthase kinase 3 alpha)
Canis lupus familiaris (dog) : GSK3A (glycogen synthase kinase 3 alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gsk3a (glycogen synthase kinase 3 alpha)
Sus scrofa (pig) : GSK3A (glycogen synthase kinase 3 alpha)
Chlorocebus sabaeus (African green monkey) : GSK3A (glycogen synthase kinase 3 alpha)
Heterocephalus glaber (naked mole-rat) : Gsk3a (glycogen synthase kinase 3 alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0182,097,244 - 82,108,238 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,097,247 - 82,108,203 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,365,717 - 83,374,707 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,505,517 - 80,514,139 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1180,583,627 - 80,592,250 (-)NCBI
Celera175,259,483 - 75,269,362 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gsk3a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620351
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.