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Gene: GSK3A (glycogen synthase kinase 3 alpha) Homo sapiens
Symbol: GSK3A
Name: glycogen synthase kinase 3 alpha
Description: Exhibits protein kinase A catalytic subunit binding activity; protein serine/threonine kinase activity; and signaling receptor binding activity. Involved in several processes, including negative regulation of glucose import; positive regulation of protein metabolic process; and regulation of mitochondrion organization. Predicted to localize to axon; cytosol; and nucleus. Implicated in amyotrophic lateral sclerosis.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp686D0638; glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A
Mus musculus (house mouse) : Gsk3a (glycogen synthase kinase 3 alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gsk3a (glycogen synthase kinase 3 alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gsk3a (glycogen synthase kinase 3 alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : GSK3A (glycogen synthase kinase 3 alpha)
Canis lupus familiaris (dog) : GSK3A (glycogen synthase kinase 3 alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gsk3a (glycogen synthase kinase 3 alpha)
Sus scrofa (pig) : GSK3A (glycogen synthase kinase 3 alpha)
Chlorocebus sabaeus (African green monkey) : GSK3A (glycogen synthase kinase 3 alpha)
Heterocephalus glaber (naked mole-rat) : Gsk3a (glycogen synthase kinase 3 alpha)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1942,230,190 - 42,242,625 (-)EnsemblGRCh38hg38GRCh38
GRCh381942,230,186 - 42,243,330 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371942,734,338 - 42,746,736 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,426,178 - 47,438,576 (-)NCBINCBI36hg18NCBI36
Build 341947,426,177 - 47,438,576NCBI
Celera1939,535,133 - 39,547,532 (-)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1939,164,764 - 39,177,148 (-)NCBIHuRef
CHM1_11942,736,013 - 42,748,418 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GSK3A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731783
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.