(5Z,8Z,11Z,13E)-15-HETE increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 15-hydroxy-5 more ... CTD PMID:15231852 (S)-nicotine increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Nicotine CTD PMID:14570768 1-Hydroxypyrene increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of UGT1A2 mRNA CTD PMID:31119341 17beta-estradiol decreases expression ISO RGD:1352957 6480464 Estradiol results in decreased expression of UGT1A3 mRNA CTD PMID:16474171 17beta-estradiol increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Estradiol, UGT1A3 protein results in increased glucuronidation of Estradiol analog CTD PMID:15117964 more ... 1H-indene increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of indene CTD PMID:15843492 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of UGT1A2 mRNA CTD PMID:20558275 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO RGD:1352957 6480464 Tetrachlorodibenzodioxin results in increased activity of UGT1A3 protein CTD PMID:16155002 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1352957 6480464 Tetrachlorodibenzodioxin results in increased expression of UGT1A3 mRNA CTD PMID:16155002 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1558284 6480464 Tetrachlorodibenzodioxin results in increased expression of UGT1A2 mRNA CTD PMID:16611356 , PMID:17949056 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of UGT1A2 mRNA CTD PMID:21346803 2,8-bis-Trifluoromethyl-4-quinoline carboxylic acid increases expression ISO RGD:1352957 6480464 Ro 21-5104 results in increased expression of UGT1A3 mRNA CTD PMID:25313206 2-amino-4,6-dinitrotoluene affects expression EXP 6480464 2-amino-4, 6-dinitrotoluene affects the expression of UGT1A2 mRNA CTD PMID:21346803 2-hydroxy-17beta-estradiol increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 2-hydroxyestradiol CTD PMID:15117964 2-hydroxyestrone increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 2-hydroxyestrone CTD PMID:15117964 2-methoxy-17beta-estradiol increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 2-Methoxyestradiol CTD PMID:15117964 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:1352957 6480464 3 more ... CTD PMID:29947894 3-methylcholanthrene increases expression ISO RGD:1352957 6480464 Methylcholanthrene results in increased expression of UGT1A2 mRNA, Methylcholanthrene results in increased expression of UGT1A3 mRNA CTD PMID:19118567 , PMID:28601433 3-phenylpropionic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 3-phenylpropionic acid CTD PMID:15117964 4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 1-(4-hydroxyphenyl)-1, 2-diphenyl-1-butene CTD PMID:29285606 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of UGT1A2 mRNA CTD PMID:21346803 4-hydroxyestrone increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 4-hydroxyestrone CTD PMID:15117964 4-methylumbelliferone increases activity ISO RGD:1352957 6480464 Hymecromone results in increased activity of UGT1A3 protein CTD PMID:26875642 4-methylumbelliferone increases metabolic processing ISO RGD:1352957 6480464 UGT1A3 protein results in increased metabolism of Hymecromone CTD PMID:31812603 4-methylumbelliferone multiple interactions ISO RGD:1352957 6480464 [UGT1A3 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide more ... CTD PMID:26875642 more ... 4-methylumbelliferone increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Hymecromone CTD PMID:15802387 , PMID:33290829 4-methylumbelliferone beta-D-glucuronide multiple interactions ISO RGD:1352957 6480464 [UGT1A3 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide more ... CTD PMID:31812603 , PMID:33290829 4-nitrophenol increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 4-nitrophenol CTD PMID:15802387 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases expression ISO RGD:1352957 6480464 Omeprazole results in increased expression of UGT1A2 mRNA, Omeprazole results in increased expression of UGT1A3 mRNA CTD PMID:19118567 9-cis-retinoic acid increases expression EXP 6480464 Alitretinoin results in increased expression of UGT1A2 mRNA CTD PMID:14620509 acetamide increases expression EXP 6480464 acetamide results in increased expression of UGT1A2 mRNA CTD PMID:31881176 acetylsalicylic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Aspirin CTD PMID:15117964 Afloqualone increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of afloqualone CTD PMID:15475412 amentoflavone decreases activity ISO RGD:1352957 6480464 amentoflavone results in decreased activity of UGT1A3 protein CTD PMID:29470958 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of UGT1A2 mRNA, Ammonium Chloride affects the expression of UGT1A3 mRNA CTD PMID:16483693 androsterone multiple interactions ISO RGD:1352957 6480464 Androsterone inhibits the reaction [[UGT1A3 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide], Androsterone inhibits the reaction [UGT1A3 protein results in increased glucuronidation of Hymecromone] CTD PMID:33290829 anthracene-1,8,9-triol increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Anthralin CTD PMID:15117964 arachidonic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Arachidonic Acid CTD PMID:15231852 Aroclor 1254 increases expression ISO RGD:1352957 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of UGT1A3 mRNA CTD PMID:17851650 atrazine affects methylation EXP 6480464 Atrazine affects the methylation of UGT1A2 gene CTD PMID:28931070 belinostat multiple interactions ISO RGD:1352957 6480464 belinostat inhibits the reaction [[UGT1A3 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide], belinostat inhibits the reaction [UGT1A3 protein results in increased glucuronidation of Hymecromone] CTD PMID:33290829 benoxaprofen affects response to substance ISO RGD:1352957 6480464 UGT1A3 affects the susceptibility to benoxaprofen CTD PMID:17880178 benzamidoxime multiple interactions ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of and results in decreased activity of benzamidoxime CTD PMID:15788365 benzo[a]pyrene increases expression ISO RGD:1558284 6480464 Benzo(a)pyrene results in increased expression of UGT1A2 mRNA CTD PMID:20127859 , PMID:20713471 beta-naphthoflavone increases expression ISO RGD:1352957 6480464 beta-Naphthoflavone results in increased expression of UGT1A2 mRNA, beta-Naphthoflavone results in increased expression of UGT1A3 mRNA CTD PMID:19118567 , PMID:28601433 betulin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of betulin CTD PMID:30776358 bilirubin IXalpha decreases activity ISO RGD:1352957 6480464 Bilirubin results in decreased activity of UGT1A3 protein CTD PMID:15334623 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1558284 6480464 Diethylhexyl Phthalate results in decreased expression of UGT1A2 mRNA CTD PMID:19245819 bisphenol A decreases expression ISO RGD:1352957 6480464 bisphenol A results in decreased expression of UGT1A3 mRNA CTD PMID:16474171 , PMID:24214726 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of UGT1A3 mRNA CTD PMID:27257137 bisphenol A increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of bisphenol A CTD PMID:18990428 Bropirimine increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of bropirimine CTD PMID:14555337 buta-1,3-diene increases expression ISO RGD:1558284 6480464 1, 3-butadiene results in increased expression of UGT1A2 mRNA CTD PMID:29038090 C.I. Natural Red 20 multiple interactions ISO RGD:1352957 6480464 shikonin inhibits the reaction [UGT1A3 protein results in increased glucuronidation of Chenodeoxycholic Acid] CTD PMID:31128210 calycosin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 7, 3'-dihydroxy-4'-methoxyisoflavone CTD PMID:25044472 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of UGT1A2 mRNA CTD PMID:18500788 chenodeoxycholic acid multiple interactions ISO RGD:1352957 6480464 [Chenodeoxycholic Acid promotes the reaction [NR1H4 protein binds to UGT1A3 promoter]] which results in increased expression of UGT1A3 mRNA more ... CTD PMID:17058234 more ... chenodeoxycholic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Chenodeoxycholic Acid CTD PMID:17058234 , PMID:31128210 chenodeoxycholic acid increases expression ISO RGD:1352957 6480464 Chenodeoxycholic Acid results in increased expression of UGT1A3 mRNA CTD PMID:20189675 , PMID:27174168 chlorogenic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Chlorogenic Acid CTD PMID:15117964 cis-caffeic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of caffeic acid CTD PMID:15117964 cisplatin affects response to substance ISO RGD:1352957 6480464 UGT1A3 protein affects the susceptibility to Cisplatin CTD PMID:16217747 clofibric acid affects response to substance ISO RGD:1352957 6480464 UGT1A3 affects the susceptibility to Clofibric Acid CTD PMID:17880178 clofibric acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Clofibric Acid CTD PMID:15117964 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of UGT1A2 mRNA CTD PMID:26577399 decanoic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of decanoic acid CTD PMID:16051554 dexamethasone affects expression EXP 6480464 Dexamethasone affects the expression of UGT1A2 mRNA CTD PMID:15102944 dichloroacetic acid increases expression ISO RGD:1558284 6480464 Dichloroacetic Acid results in increased expression of UGT1A2 mRNA CTD PMID:28962523 diclofenac decreases activity ISO RGD:1352957 6480464 Diclofenac results in decreased activity of UGT1A3 protein CTD PMID:15334623 diclofenac increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Diclofenac CTD PMID:15117964 , PMID:15843492 diethylstilbestrol increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Diethylstilbestrol CTD PMID:23126256 diethylstilbestrol multiple interactions ISO RGD:1352957 6480464 Phenylbutazone inhibits the reaction [UGT1A3 protein results in increased glucuronidation of Diethylstilbestrol] CTD PMID:23126256 diflunisal increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Diflunisal CTD PMID:15117964 dimethylarsinic acid multiple interactions ISO RGD:1558284 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of UGT1A2 mRNA CTD PMID:34876320 diphenylacetic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of diphenylacetic acid CTD PMID:15117964 dodecanoic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of lauric acid CTD PMID:16051554 entacapone increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of entacapone CTD PMID:15802387 estriol increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Estriol, UGT1A3 protein results in increased glucuronidation of Estriol analog CTD PMID:15117964 estrone increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Estrone, UGT1A3 protein results in increased glucuronidation of Estrone analog CTD PMID:15117964 , PMID:15472229 etodolac increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Etodolac CTD PMID:15535975 etoposide increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Etoposide CTD PMID:17151191 ezetimibe increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Ezetimibe CTD PMID:14977865 farnesol increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 fenofibrate increases expression ISO RGD:1352957 6480464 Fenofibrate results in increased expression of UGT1A3 mRNA CTD PMID:17058234 fenoprofen increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Fenoprofen CTD PMID:15117964 fenthion increases expression ISO RGD:1558284 6480464 Fenthion results in increased expression of UGT1A2 mRNA CTD PMID:34813904 ferulic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of ferulic acid CTD PMID:15117964 fipronil increases expression EXP 6480464 fipronil results in increased expression of UGT1A2 mRNA CTD PMID:23962444 flunitrazepam decreases activity ISO RGD:1352957 6480464 Flunitrazepam results in decreased activity of UGT1A3 protein CTD PMID:15334623 flurbiprofen increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Flurbiprofen CTD PMID:15117964 , PMID:15843492 furosemide increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Furosemide CTD PMID:15117964 galangin decreases activity ISO RGD:1352957 6480464 galangin results in decreased activity of UGT1A3 protein CTD PMID:35063619 genistein decreases expression ISO RGD:1352957 6480464 Genistein results in decreased expression of UGT1A3 mRNA CTD PMID:16474171 genistein increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Genistein CTD PMID:15988124 glabridin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of glabridin CTD PMID:25765239 glutathione increases expression EXP 6480464 Glutathione deficiency results in increased expression of UGT1A2 mRNA, Glutathione deficiency results in increased expression of UGT1A3 mRNA CTD PMID:15345336 Grepafloxacin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of grepafloxacin CTD PMID:15769885 GW 4064 multiple interactions ISO RGD:1352957 6480464 [GW 4064 results in increased activity of NR1H4 protein] which results in increased expression of UGT1A3 mRNA CTD PMID:20189675 GW 7647 increases expression EXP 6480464 GW 7647 results in increased expression of UGT1A3 mRNA CTD PMID:19631232 GW 7647 multiple interactions EXP 6480464 GW 7647 promotes the reaction [Phenobarbital results in increased expression of UGT1A3 mRNA] CTD PMID:19631232 hydratropic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of hydratropic acid CTD PMID:15117964 ibuprofen increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Ibuprofen CTD PMID:15117964 , PMID:15843492 indole-3-methanol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of UGT1A2 mRNA, [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of UGT1A3 mRNA CTD PMID:22129741 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of UGT1A2 mRNA, indole-3-carbinol affects the expression of UGT1A3 mRNA CTD PMID:21396975 indometacin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Indomethacin CTD PMID:15117964 , PMID:15843492 indoprofen increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Indoprofen CTD PMID:15117964 isoprenaline increases expression ISO RGD:1558284 6480464 Isoproterenol results in increased expression of UGT1A2 mRNA CTD PMID:20003209 isovaleric acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of isovaleric acid analog CTD PMID:15117964 kaempferol increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of kaempferol CTD PMID:16738032 kaempferol decreases activity ISO RGD:1352957 6480464 kaempferol results in decreased activity of UGT1A3 protein CTD PMID:35063619 kaempferol affects glucuronidation ISO RGD:1352957 6480464 UGT1A3 mutant form affects the glucuronidation of kaempferol CTD PMID:16738032 ketoprofen increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Ketoprofen CTD PMID:15535975 , PMID:15843492 kojic acid multiple interactions ISO RGD:1558284 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of UGT1A2 mRNA CTD PMID:17917374 L-ascorbic acid multiple interactions ISO RGD:1558284 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of UGT1A2 mRNA CTD PMID:17917374 lamotrigine increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of lamotrigine CTD PMID:17151188 lapatinib decreases activity ISO RGD:1352957 6480464 Lapatinib results in decreased activity of UGT1A3 protein CTD PMID:31299240 lapatinib multiple interactions ISO RGD:1352957 6480464 [Lapatinib results in decreased activity of UGT1A3 protein] which results in decreased glucuronidation of obeticholic acid, [Lapatinib results in decreased activity of UGT1A3 protein] which results in decreased glucuronidation of Ursodeoxycholic Acid CTD PMID:31299240 Licochalcone A multiple interactions ISO RGD:1352957 6480464 licochalcone A inhibits the reaction [Hymecromone results in increased activity of UGT1A3 protein] CTD PMID:26875642 lithocholic acid increases expression ISO RGD:1352957 6480464 Lithocholic Acid results in increased expression of UGT1A3 mRNA CTD PMID:20189675 luteolin affects glucuronidation ISO RGD:1352957 6480464 UGT1A3 mutant form affects the glucuronidation of Luteolin CTD PMID:16738032 luteolin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Luteolin CTD PMID:16738032 mefenamic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Mefenamic Acid CTD PMID:15117964 MeIQx multiple interactions ISO RGD:1352957 6480464 [xanthohumol co-treated with 2-amino-3 more ... CTD PMID:22138251 methoxychlor increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Methoxychlor metabolite CTD PMID:15205390 methyl salicylate increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of methyl salicylate CTD PMID:15117964 methylarsonic acid multiple interactions ISO RGD:1558284 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of UGT1A2 mRNA CTD PMID:34876320 mono(2-ethylhexyl) phthalate increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of mono-(2-ethylhexyl)phthalate CTD PMID:27071666 morin decreases activity ISO RGD:1352957 6480464 morin results in decreased activity of UGT1A3 protein CTD PMID:35063619 morphine increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Morphine CTD PMID:12920162 moxifloxacin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of moxifloxacin CTD PMID:15769885 Muraglitazar increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of muraglitazar CTD PMID:17898154 myricetin decreases activity ISO RGD:1352957 6480464 myricetin results in decreased activity of UGT1A3 protein CTD PMID:35063619 N-hydroxy-PhIP increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4, 5-b)pyridine CTD PMID:15310245 N-nitrosodiethylamine multiple interactions ISO RGD:1558284 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of UGT1A2 mRNA CTD PMID:17917374 N-nitrosodiethylamine multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of UGT1A2 mRNA, [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of UGT1A3 mRNA CTD PMID:22129741 naproxen increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Naproxen CTD PMID:15535975 , PMID:15843492 nicotine increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Nicotine CTD PMID:14570768 Nor-9-carboxy-delta9-THC multiple interactions ISO RGD:1352957 6480464 [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of UGT1A3 gene CTD PMID:30521419 obeticholic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of obeticholic acid CTD PMID:31299240 obeticholic acid multiple interactions ISO RGD:1352957 6480464 [Lapatinib results in decreased activity of UGT1A3 protein] which results in decreased glucuronidation of obeticholic acid CTD PMID:31299240 ofloxacin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Ofloxacin CTD PMID:15769885 omeprazole increases expression ISO RGD:1352957 6480464 Omeprazole results in increased expression of UGT1A2 mRNA, Omeprazole results in increased expression of UGT1A3 mRNA CTD PMID:19118567 ortho-vanillin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of 2-vanillin CTD PMID:15117964 osimertinib decreases activity ISO RGD:1352957 6480464 osimertinib results in decreased activity of UGT1A3 protein CTD PMID:34044055 paracetamol increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Acetaminophen CTD PMID:15117964 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of UGT1A2 mRNA, Acetaminophen results in decreased expression of UGT1A3 mRNA CTD PMID:33387578 perfluorodecanoic acid increases expression ISO RGD:1558284 6480464 perfluorodecanoic acid results in increased expression of UGT1A2 mRNA CTD PMID:27344344 perfluorodecanoic acid multiple interactions ISO RGD:1558284 6480464 PPARA protein affects the reaction [perfluorodecanoic acid results in increased expression of UGT1A2 mRNA] CTD PMID:27344344 perfluorooctane-1-sulfonic acid affects expression ISO RGD:1558284 6480464 perfluorooctane sulfonic acid affects the expression of UGT1A2 mRNA CTD PMID:19429403 perfluorooctanoic acid affects expression ISO RGD:1558284 6480464 perfluorooctanoic acid affects the expression of UGT1A2 mRNA CTD PMID:19429403 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of UGT1A2 mRNA, Phenobarbital results in increased expression of UGT1A3 mRNA CTD PMID:16940010 , PMID:19631232 phenobarbital multiple interactions EXP 6480464 GW 7647 promotes the reaction [Phenobarbital results in increased expression of UGT1A3 mRNA], pirinixic acid promotes the reaction [Phenobarbital results in increased expression of UGT1A3 mRNA] CTD PMID:19631232 phenylbutazone multiple interactions ISO RGD:1352957 6480464 Phenylbutazone inhibits the reaction [UGT1A3 protein results in increased glucuronidation of Diethylstilbestrol] CTD PMID:23126256 pimecrolimus multiple interactions ISO RGD:1352957 6480464 pimecrolimus inhibits the reaction [Rifampin results in increased expression of UGT1A3 mRNA] CTD PMID:29356861 pirinixic acid multiple interactions EXP 6480464 pirinixic acid promotes the reaction [Phenobarbital results in increased expression of UGT1A3 mRNA] CTD PMID:19631232 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of UGT1A3 mRNA CTD PMID:19631232 pirinixic acid increases expression ISO RGD:1352957 6480464 pirinixic acid results in increased expression of UGT1A3 mRNA CTD PMID:17058234 , PMID:17151188 ponasterone A increases expression ISO RGD:1352957 6480464 ponasterone A results in increased expression of UGT1A3 protein CTD PMID:17058234 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of UGT1A2 mRNA CTD PMID:19162173 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:1352957 6480464 Pregnenolone Carbonitrile results in increased expression of UGT1A3 mRNA CTD PMID:16155002 probenecid affects response to substance ISO RGD:1352957 6480464 UGT1A3 affects the susceptibility to Probenecid CTD PMID:17880178 pterostilbene increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of pterostilbene CTD PMID:23965644 pterostilbene multiple interactions ISO RGD:1352957 6480464 pterostilbene inhibits the reaction [[UGT1A3 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 pterostilbene decreases activity ISO RGD:1352957 6480464 pterostilbene results in decreased activity of UGT1A3 protein CTD PMID:31812603 puerarin increases metabolic processing ISO RGD:1352957 6480464 UGT1A3 protein results in increased metabolism of puerarin CTD PMID:22648071 pyrazinecarboxamide increases expression EXP 6480464 Pyrazinamide results in increased expression of UGT1A2 mRNA CTD PMID:22431067 quercetin increases expression EXP 6480464 Quercetin results in increased expression of UGT1A2 mRNA CTD PMID:21565894 quercetin decreases activity ISO RGD:1352957 6480464 Quercetin results in decreased activity of UGT1A3 protein CTD PMID:35063619 quercetin affects glucuronidation ISO RGD:1352957 6480464 UGT1A3 mutant form affects the glucuronidation of Quercetin CTD PMID:16738032 quercetin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Quercetin CTD PMID:15609409 , PMID:16738032 resveratrol affects glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein affects the glucuronidation of resveratrol CTD PMID:23965644 rifampicin increases expression ISO RGD:1352957 6480464 Rifampin results in increased expression of UGT1A3 mRNA CTD PMID:25313206 , PMID:29356861 rifampicin multiple interactions ISO RGD:1352957 6480464 pimecrolimus inhibits the reaction [Rifampin results in increased expression of UGT1A3 mRNA] CTD PMID:29356861 salicylic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Salicylic Acid CTD PMID:15117964 scopoletin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Scopoletin CTD PMID:15802387 sevoflurane affects expression EXP 6480464 sevoflurane affects the expression of UGT1A2 mRNA, sevoflurane affects the expression of UGT1A3 mRNA CTD PMID:15967596 Shikonin multiple interactions ISO RGD:1352957 6480464 shikonin inhibits the reaction [UGT1A3 protein results in increased glucuronidation of Chenodeoxycholic Acid] CTD PMID:31128210 Sitafloxacin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of sitafloxacin CTD PMID:15769885 sodium arsenate multiple interactions ISO RGD:1558284 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of UGT1A2 mRNA CTD PMID:34876320 sodium arsenite decreases expression ISO RGD:1558284 6480464 sodium arsenite results in decreased expression of UGT1A2 mRNA CTD PMID:17451858 sodium arsenite multiple interactions ISO RGD:1558284 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of UGT1A2 mRNA CTD PMID:34876320 spironolactone increases expression ISO RGD:1558284 6480464 Spironolactone results in increased expression of UGT1A2 mRNA CTD PMID:19144771 sulindac increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Sulindac CTD PMID:15843492 sulindac sulfone increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of sulindac sulfone CTD PMID:15843492 tetrachloroethene increases expression ISO RGD:1558284 6480464 Tetrachloroethylene results in increased expression of UGT1A2 mRNA CTD PMID:28973375 tetrachloromethane affects expression ISO RGD:1558284 6480464 Carbon Tetrachloride affects the expression of UGT1A2 mRNA CTD PMID:17484886 trans-caffeic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of caffeic acid CTD PMID:15117964 trans-cinnamic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of cinnamic acid CTD PMID:15117964 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of UGT1A2 mRNA, Trichloroethylene results in increased expression of UGT1A3 mRNA CTD PMID:33387578 triclocarban multiple interactions ISO RGD:1352957 6480464 NR1I3 gene mutant form inhibits the reaction [triclocarban results in increased expression of UGT1A3 mRNA] CTD PMID:22761658 triclocarban increases expression ISO RGD:1352957 6480464 triclocarban results in increased expression of UGT1A3 mRNA CTD PMID:22761658 ursodeoxycholic acid multiple interactions ISO RGD:1352957 6480464 [Lapatinib results in decreased activity of UGT1A3 protein] which results in decreased glucuronidation of Ursodeoxycholic Acid CTD PMID:31299240 ursodeoxycholic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Ursodeoxycholic Acid CTD PMID:31299240 valproic acid decreases methylation ISO RGD:1352957 6480464 Valproic Acid results in decreased methylation of UGT1A3 gene CTD PMID:29154799 , PMID:29501571 valproic acid increases expression ISO RGD:1352957 6480464 Valproic Acid results in increased expression of UGT1A3 mRNA CTD PMID:29501571 vanillic acid increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of Vanillic Acid CTD PMID:15117964 vanillin increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of vanillin CTD PMID:15117964 vitamin E decreases expression EXP 6480464 Vitamin E results in decreased expression of UGT1A2 mRNA CTD PMID:28923436 vorinostat increases glucuronidation ISO RGD:1352957 6480464 UGT1A3 protein results in increased glucuronidation of vorinostat CTD PMID:25393417 vorinostat multiple interactions ISO RGD:1352957 6480464 [Warfarin binds to and results in increased activity of UGT1A3 protein] which results in increased glucuronidation of vorinostat, Warfarin promotes the reaction [UGT1A3 protein results in increased glucuronidation of vorinostat] CTD PMID:25393417 warfarin multiple interactions ISO RGD:1352957 6480464 [Warfarin binds to and results in increased activity of UGT1A3 protein] which results in increased glucuronidation of vorinostat more ... CTD PMID:25393417 xanthohumol multiple interactions ISO RGD:1352957 6480464 [xanthohumol co-treated with 2-amino-3 more ... CTD PMID:22138251 zinc atom increases expression ISO RGD:1352957 6480464 Zinc deficiency results in increased expression of UGT1A3 mRNA CTD PMID:18356318 zinc(0) increases expression ISO RGD:1352957 6480464 Zinc deficiency results in increased expression of UGT1A3 mRNA CTD PMID:18356318
