Gene: Casq2 (calsequestrin 2) Rattus norvegicus
Symbol: Casq2
Name: calsequestrin 2
Description: ENCODES a protein that exhibits protein homodimerization activity; protein kinase C binding; calcium ion binding (ortholog); INVOLVED IN negative regulation of ryanodine-sensitive calcium-release channel activity; regulation of cardiac muscle cell contraction; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH congestive heart failure; Diabetic Cardiomyopathies; supravalvular aortic stenosis; FOUND IN sarcoplasmic reticulum; Z disc; cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; all-trans-retinoic acid
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: calsequestrin 2 (cardiac muscle); calsequestrin, cardiac muscle isoform; calsequestrin-2; cardCSQ; SR calcium binding protein
Homo sapiens (human) : CASQ2 (calsequestrin 2)  HGNC  Alliance
Mus musculus (house mouse) : Casq2 (calsequestrin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casq2 (calsequestrin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CASQ2 (calsequestrin 2)
Canis lupus familiaris (dog) : CASQ2 (calsequestrin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casq2 (calsequestrin 2)
Sus scrofa (pig) : CASQ2 (calsequestrin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02204,512,361 - 204,568,643 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02223,945,611 - 224,001,893 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42197,182,938 - 197,239,201 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12197,145,718 - 197,201,199 (+)NCBI
Celera2181,958,395 - 182,014,660 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Casq2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2276
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE