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Gene: Casq2 (calsequestrin 2) Mus musculus
Symbol: Casq2
Name: calsequestrin 2
Description: Exhibits calcium ion binding activity. Involved in regulation of heart rate; regulation of ion transmembrane transport; and sarcomere organization. Localizes to the Z disc; junctional membrane complex; and sarcoplasmic reticulum lumen. Used to study catecholaminergic polymorphic ventricular tachycardia 2. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia 2. Is expressed in several structures, including cerebellum; diaphragm; heart; male reproductive system; and tongue. Orthologous to human CASQ2 (calsequestrin 2); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 4,4'-diaminodiphenylmethane; 4,4'-sulfonyldiphenol; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA033488; AW146219; calsequestrin, cardiac muscle isoform; calsequestrin-2; cardiac calsequestrin; cCSQ; Csq2; ESTM52; MGC115896
Homo sapiens (human) : CASQ2 (calsequestrin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Casq2 (calsequestrin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casq2 (calsequestrin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CASQ2 (calsequestrin 2)
Canis lupus familiaris (dog) : CASQ2 (calsequestrin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casq2 (calsequestrin 2)
Sus scrofa (pig) : CASQ2 (calsequestrin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm383102,086,415 - 102,146,514 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373101,890,433 - 101,950,437 (+)NCBIGRCm37mm9NCBIm37
MGSCv363102,205,026 - 102,275,310 (+)NCBImm8
Celera3104,291,130 - 104,350,741 (+)NCBICelera
Cytogenetic Map3 F2.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Casq2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737299
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.