(E)-cinnamyl alcohol increases expression ISO RGD:1349499 6480464 cinnamyl alcohol results in increased expression of UGT1A6 mRNA CTD PMID:20566472 1,2-dimethylhydrazine decreases expression ISO RGD:1619652 6480464 1, 2-Dimethylhydrazine results in decreased expression of UGT1A6B mRNA CTD PMID:22206623 1,7-phenanthroline multiple interactions EXP 6480464 1, 7-phenanthroline promotes the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of UGT1A6 protein] CTD PMID:17967931 1,7-phenanthroline increases expression EXP 6480464 1, 7-phenanthroline results in increased expression of UGT1A6 protein CTD PMID:17967931 1-chloro-2,4-dinitrobenzene increases expression ISO RGD:1349499 6480464 Dinitrochlorobenzene results in increased expression of UGT1A6 mRNA CTD PMID:20566472 1-Hydroxypyrene increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 1-naphthol multiple interactions EXP 6480464 Methylcholanthrene promotes the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol], Paraquat promotes the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol] CTD PMID:19023562 1-naphthol multiple interactions ISO RGD:1349499 6480464 beta-Naphthoflavone promotes the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol] more ... CTD PMID:22265884 , PMID:7646562 1-naphthol increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of 1-naphthol CTD PMID:12756209 more ... 1-naphthol increases glucuronidation EXP 6480464 UGT1A6 protein results in increased glucuronidation of 1-naphthol CTD PMID:12153725 more ... 1-naphthol affects metabolic processing EXP 6480464 UGT1A6 gene polymorphism affects the metabolism of 1-naphthol, UGT1A6 protein affects the metabolism of 1-naphthol CTD PMID:15336321 , PMID:9429234 1-naphthol increases metabolic processing EXP 6480464 UGT1A6 protein results in increased metabolism of 1-naphthol CTD PMID:9429234 17alpha-ethynylestradiol decreases expression ISO RGD:1619652 6480464 Ethinyl Estradiol results in decreased expression of UGT1A6 mRNA CTD PMID:17942748 17alpha-ethynylestradiol multiple interactions ISO RGD:1619652 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UGT1A6 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of UGT1A6 mRNA CTD PMID:32741896 17beta-estradiol multiple interactions ISO RGD:1349499 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of UGT1A6 mRNA CTD PMID:30165855 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of UGT1A6 mRNA CTD PMID:32741896 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1619652 6480464 2 more ... CTD PMID:21851831 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of UGT1A6 mRNA] CTD PMID:12948865 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO RGD:1349499 6480464 Tetrachlorodibenzodioxin results in increased activity of UGT1A6 protein CTD PMID:12948865 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1349499 6480464 Tetrachlorodibenzodioxin affects the expression of UGT1A6 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1349499 6480464 Tetrachlorodibenzodioxin results in increased expression of UGT1A6 mRNA, Tetrachlorodibenzodioxin results in increased expression of UGT1A6 protein CTD PMID:10220484 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1349499 6480464 AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of UGT1A6 mRNA] more ... CTD PMID:11368516 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1619652 6480464 Tetrachlorodibenzodioxin results in increased expression of UGT1A6 mRNA, Tetrachlorodibenzodioxin results in increased expression of UGT1A6B mRNA CTD PMID:11043581 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1619652 6480464 2 more ... CTD PMID:11043581 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of UGT1A6 mRNA CTD PMID:11836014 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of UGT1A6 mRNA CTD PMID:22298810 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO RGD:1619652 6480464 2 more ... CTD PMID:24713691 2,4,6-trinitrobenzenesulfonic acid decreases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in decreased expression of UGT1A6 mRNA CTD PMID:12163651 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of UGT1A6 mRNA CTD PMID:21346803 2,4,6-Triphenyl-1-hexene decreases expression ISO RGD:1619652 6480464 2 more ... CTD PMID:18560529 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of UGT1A6 mRNA CTD PMID:21346803 2-amino-4,6-dinitrotoluene affects expression EXP 6480464 2-amino-4, 6-dinitrotoluene affects the expression of UGT1A6 mRNA CTD PMID:21346803 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA CTD PMID:12948865 2-tert-butylhydroquinone multiple interactions ISO RGD:1349499 6480464 AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA] CTD PMID:12948865 2-tert-butylhydroquinone increases activity ISO RGD:1349499 6480464 2-tert-butylhydroquinone results in increased activity of UGT1A6 protein CTD PMID:12948865 2-tert-butylhydroquinone increases expression ISO RGD:1349499 6480464 2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA CTD PMID:10220484 , PMID:12948865 2-tert-butylhydroquinone multiple interactions EXP 6480464 AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA] CTD PMID:12948865 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:19692669 , PMID:20959002 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:1619652 6480464 3 more ... CTD PMID:19144771 3,3',5-triiodo-L-thyronine increases expression EXP 6480464 Triiodothyronine results in increased expression of UGT1A6 mRNA CTD PMID:11299074 3,3',5-triiodo-L-thyronine multiple interactions EXP 6480464 Vitamin A inhibits the reaction [Triiodothyronine results in increased expression of UGT1A6 mRNA] CTD PMID:11299074 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of UGT1A6 protein CTD PMID:34915118 3-Ethylphenol increases metabolic processing EXP 6480464 UGT1A6 protein results in increased metabolism of 3-ethylphenol CTD PMID:9429234 3-Ethylphenol affects metabolic processing EXP 6480464 UGT1A6 gene polymorphism affects the metabolism of 3-ethylphenol CTD PMID:9429234 3-methylcholanthrene multiple interactions EXP 6480464 [Methylcholanthrene results in increased activity of UGT1A6 protein] which affects the metabolism of Benzene more ... CTD PMID:19023562 more ... 3-methylcholanthrene multiple interactions ISO RGD:1349499 6480464 [Methylcholanthrene co-treated with Oxygen deficiency] results in decreased expression of UGT1A6 mRNA, Oxygen deficiency inhibits the reaction [Methylcholanthrene results in increased expression of UGT1A6 mRNA] CTD PMID:33811995 3-methylcholanthrene increases expression ISO RGD:1349499 6480464 Methylcholanthrene results in increased expression of UGT1A6 mRNA CTD PMID:19118567 more ... 3-methylcholanthrene increases activity EXP 6480464 Methylcholanthrene results in increased activity of UGT1A6 protein CTD PMID:1981726 , PMID:8263600 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of UGT1A6 mRNA CTD PMID:11328961 more ... 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of UGT1A6 mRNA CTD PMID:21346803 4-hydroxycoumarin increases metabolic processing EXP 6480464 UGT1A6 protein results in increased metabolism of 4-hydroxycoumarin CTD PMID:9429234 4-hydroxycoumarin affects metabolic processing EXP 6480464 UGT1A6 gene polymorphism affects the metabolism of 4-hydroxycoumarin CTD PMID:9429234 4-hydroxyphenytoin multiple interactions ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of and results in decreased activity of hydroxyphenytoin CTD PMID:15855726 4-methylumbelliferone affects metabolic processing EXP 6480464 UGT1A6 gene polymorphism affects the metabolism of Hymecromone CTD PMID:9429234 4-methylumbelliferone multiple interactions ISO RGD:1349499 6480464 [UGT1A6 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide more ... CTD PMID:18214896 more ... 4-methylumbelliferone increases metabolic processing ISO RGD:1349499 6480464 UGT1A6 protein results in increased metabolism of Hymecromone CTD PMID:31812603 4-methylumbelliferone increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of Hymecromone CTD PMID:15802387 more ... 4-methylumbelliferone increases activity ISO RGD:1349499 6480464 Hymecromone results in increased activity of UGT1A6 protein CTD PMID:26875642 4-methylumbelliferone increases metabolic processing EXP 6480464 UGT1A6 protein results in increased metabolism of Hymecromone CTD PMID:9429234 4-methylumbelliferone beta-D-glucuronide multiple interactions ISO RGD:1349499 6480464 [UGT1A6 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide more ... CTD PMID:31812603 , PMID:33290829 4-nitrophenol affects metabolic processing EXP 6480464 UGT1A6 gene polymorphism affects the metabolism of 4-nitrophenol CTD PMID:9429234 4-nitrophenol increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of 4-nitrophenol CTD PMID:15284531 more ... 4-nitrophenol affects glucuronidation ISO RGD:1349499 6480464 UGT1A6 gene polymorphism affects the glucuronidation of 4-nitrophenol, UGT1A6 gene SNP affects the glucuronidation of 4-nitrophenol CTD PMID:15284531 , PMID:15761113 4-nitrophenol increases metabolic processing EXP 6480464 UGT1A6 protein results in increased metabolism of 4-nitrophenol CTD PMID:9429234 4-nitrophenol increases glucuronidation EXP 6480464 UGT1A6 protein results in increased glucuronidation of 4-nitrophenol CTD PMID:15921999 4-tert-butylphenol affects metabolic processing EXP 6480464 UGT1A6 gene polymorphism affects the metabolism of butylphen CTD PMID:9429234 4-tert-butylphenol increases metabolic processing EXP 6480464 UGT1A6 protein results in increased metabolism of butylphen CTD PMID:9429234 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases expression EXP 6480464 Omeprazole results in increased expression of UGT1A6 mRNA CTD PMID:19118567 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases expression ISO RGD:1349499 6480464 Omeprazole results in increased expression of UGT1A6 mRNA CTD PMID:19118567 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions EXP 6480464 [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA CTD PMID:22687989 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of UGT1A6 mRNA CTD PMID:25825206 9-cis-retinoic acid decreases expression EXP 6480464 Alitretinoin results in decreased expression of UGT1A6 mRNA CTD PMID:14620509 acetamide increases expression EXP 6480464 acetamide results in increased expression of UGT1A6 mRNA CTD PMID:31881176 acetylsalicylic acid affects expression EXP 6480464 Aspirin affects the expression of UGT1A6 mRNA CTD PMID:12800193 acrolein increases expression ISO RGD:1619652 6480464 Acrolein results in increased expression of UGT1A6 mRNA CTD PMID:12763045 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of UGT1A6 mRNA CTD PMID:28959563 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of UGT1A6 mRNA CTD PMID:23630614 more ... aflatoxin B1 multiple interactions ISO RGD:1349499 6480464 [Aflatoxin B1 co-treated with Oxygen deficiency] results in decreased expression of UGT1A6 mRNA CTD PMID:33811995 aflatoxin B1 increases expression ISO RGD:1349499 6480464 Aflatoxin B1 results in increased expression of UGT1A6 mRNA CTD PMID:27153756 aflatoxin B1 decreases methylation ISO RGD:1349499 6480464 Aflatoxin B1 results in decreased methylation of UGT1A6 gene CTD PMID:27153756 aldehydo-D-glucose multiple interactions ISO RGD:1349499 6480464 TPH1 protein affects the reaction [UGT1A6A protein affects the reaction [sodium arsenite inhibits the reaction [Glucose results in increased secretion of INS protein]]], UGT1A6A protein affects the reaction [sodium arsenite inhibits the reaction [Glucose results in increased secretion of INS protein]] CTD PMID:30562058 all-trans-retinol multiple interactions EXP 6480464 Vitamin A inhibits the reaction [Triiodothyronine results in increased expression of UGT1A6 mRNA] CTD PMID:11299074 all-trans-retinol decreases expression EXP 6480464 Vitamin A deficiency results in decreased expression of UGT1A6 mRNA CTD PMID:12163651 alpha-hexachlorocyclohexane increases expression EXP 6480464 alpha-hexachlorocyclohexane results in increased expression of UGT1A6 mRNA CTD PMID:17785943 alpha-hexylcinnamaldehyde increases expression ISO RGD:1349499 6480464 hexyl cinnamic aldehyde results in increased expression of UGT1A6 mRNA CTD PMID:20566472 amentoflavone decreases activity ISO RGD:1349499 6480464 amentoflavone results in decreased activity of UGT1A6 protein CTD PMID:29470958 , PMID:32421801 amentoflavone multiple interactions ISO RGD:1349499 6480464 amentoflavone inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 4-cresol] CTD PMID:32421801 aminoguanidine multiple interactions ISO RGD:1619652 6480464 pimagedine inhibits the reaction [Spermidine results in increased expression of UGT1A6 mRNA] CTD PMID:12763045 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of UGT1A6 mRNA CTD PMID:16483693 andrographolide multiple interactions ISO RGD:1619652 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in increased expression of UGT1A6 mRNA CTD PMID:19737545 andrographolide increases expression ISO RGD:1619652 6480464 andrographolide results in increased expression of UGT1A6 mRNA CTD PMID:19737545 antimonite multiple interactions ISO RGD:1349499 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of UGT1A6 mRNA CTD PMID:32076005 aristolochic acid A multiple interactions EXP 6480464 [aristolochic acid I co-treated with aristolochic acid II] results in increased expression of UGT1A6 mRNA CTD PMID:23912714 aristolochic acid A decreases expression ISO RGD:1349499 6480464 aristolochic acid I results in decreased expression of UGT1A6 mRNA CTD PMID:33212167 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of UGT1A6 mRNA CTD PMID:18178546 , PMID:22659317 Aroclor 1254 increases expression ISO RGD:1349499 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of UGT1A6 mRNA CTD PMID:17851650 arsane multiple interactions ISO RGD:1349499 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of UGT1A6 mRNA CTD PMID:32525701 arsenic atom multiple interactions ISO RGD:1349499 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of UGT1A6 mRNA CTD PMID:32525701 arsenite(3-) multiple interactions ISO RGD:1349499 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of UGT1A6 mRNA CTD PMID:32076005 arsenous acid increases expression ISO RGD:1349499 6480464 Arsenic Trioxide results in increased expression of UGT1A6 mRNA CTD PMID:20458559 , PMID:29633893 Auriculasin decreases activity ISO RGD:1349499 6480464 auriculasin results in decreased activity of UGT1A6 protein CTD PMID:31515991 Bandrowski's base increases expression ISO RGD:1349499 6480464 Bandrowski's base results in increased expression of UGT1A6 mRNA CTD PMID:20566472 belinostat multiple interactions ISO RGD:1349499 6480464 belinostat inhibits the reaction [[UGT1A6 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide], belinostat inhibits the reaction [UGT1A6 protein results in increased glucuronidation of Hymecromone] CTD PMID:33290829 benzene affects expression EXP 6480464 Benzene affects the expression of UGT1A6 mRNA CTD PMID:15878777 benzene increases metabolic processing ISO RGD:1349499 6480464 UGT1A6 protein results in increased metabolism of Benzene CTD PMID:17479406 benzene multiple interactions EXP 6480464 [Methylcholanthrene results in increased activity of UGT1A6 protein] which affects the metabolism of Benzene CTD PMID:1981726 benzo[a]pyrene multiple interactions EXP 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Phenobarbital promotes the reaction [Benzo(a)pyrene results in increased expression of UGT1A6 mRNA]], Phenobarbital promotes the reaction [Benzo(a)pyrene results in increased expression of UGT1A6 mRNA] CTD PMID:25489928 benzo[a]pyrene multiple interactions ISO RGD:1349499 6480464 [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a more ... CTD PMID:15566942 , PMID:26438400 benzo[a]pyrene increases expression ISO RGD:1349499 6480464 Benzo(a)pyrene results in increased expression of UGT1A6 mRNA CTD PMID:15566942 more ... benzo[a]pyrene increases activity ISO RGD:1349499 6480464 Benzo(a)pyrene results in increased activity of UGT1A6 protein CTD PMID:17065433 benzo[a]pyrene affects methylation ISO RGD:1349499 6480464 Benzo(a)pyrene affects the methylation of UGT1A6 3' UTR, Benzo(a)pyrene affects the methylation of UGT1A6 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:1619652 6480464 Benzo(a)pyrene results in increased expression of UGT1A6B mRNA CTD PMID:21569818 benzo[a]pyrene affects expression ISO RGD:1619652 6480464 Benzo(a)pyrene affects the expression of UGT1A6 mRNA CTD PMID:22342234 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of UGT1A6 mRNA CTD PMID:25489928 benzo[b]fluoranthene multiple interactions ISO RGD:1349499 6480464 [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a, l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of UGT1A6 mRNA CTD PMID:15566942 Benzo[k]fluoranthene increases expression ISO RGD:1349499 6480464 benzo(k)fluoranthene results in increased expression of UGT1A6 mRNA CTD PMID:15566942 Benzo[k]fluoranthene multiple interactions ISO RGD:1349499 6480464 [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a, l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of UGT1A6 mRNA CTD PMID:15566942 Benzyl viologen increases expression EXP 6480464 Benzyl Viologen results in increased expression of UGT1A6 mRNA CTD PMID:22846377 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UGT1A6 mRNA CTD PMID:18164116 beta-naphthoflavone increases expression ISO RGD:1349499 6480464 beta-Naphthoflavone results in increased expression of UGT1A6 mRNA CTD PMID:12948865 more ... beta-naphthoflavone multiple interactions ISO RGD:1349499 6480464 beta-Naphthoflavone promotes the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol] CTD PMID:7646562 beta-naphthoflavone increases expression ISO RGD:1619652 6480464 beta-Naphthoflavone results in increased expression of UGT1A6 mRNA CTD PMID:19144771 , PMID:19737545 beta-naphthoflavone multiple interactions ISO RGD:1619652 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in increased expression of UGT1A6 mRNA CTD PMID:19737545 beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of UGT1A6 mRNA CTD PMID:12883083 more ... bis(2-ethylhexyl) phthalate increases expression ISO RGD:1619652 6480464 Diethylhexyl Phthalate results in increased expression of UGT1A6 mRNA CTD PMID:19144771 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of UGT1A6 mRNA CTD PMID:25181051 bisphenol A decreases expression ISO RGD:1349499 6480464 bisphenol A results in decreased expression of UGT1A6 mRNA CTD PMID:24214726 bisphenol A multiple interactions ISO RGD:1349499 6480464 bisphenol A inhibits the reaction [UGT1A6 protein results in increased glucuronidation of Hymecromone], bisphenol A inhibits the reaction [UGT1A6 protein results in increased glucuronidation of Serotonin] CTD PMID:18214896 bosentan decreases expression ISO RGD:1349499 6480464 Bosentan results in decreased expression of UGT1A6 mRNA CTD PMID:29761207 buspirone increases expression EXP 6480464 Buspirone results in increased expression of UGT1A6 mRNA CTD PMID:24136188 buta-1,3-diene increases expression ISO RGD:1619652 6480464 1, 3-butadiene results in increased expression of UGT1A6B mRNA CTD PMID:29038090 butylated hydroxyanisole increases expression ISO RGD:1619652 6480464 Butylated Hydroxyanisole results in increased expression of UGT1A6 mRNA CTD PMID:19144771 butyric acid increases expression ISO RGD:1349499 6480464 Butyric Acid results in increased expression of UGT1A6 mRNA CTD PMID:30439556 camptothecin decreases methylation ISO RGD:1349499 6480464 Camptothecin results in decreased methylation of UGT1A6 gene CTD PMID:30720231 carbamazepine increases expression EXP 6480464 Carbamazepine results in increased expression of UGT1A6 mRNA CTD PMID:17381134 carboplatin decreases expression EXP 6480464 Carboplatin results in decreased expression of UGT1A6 mRNA CTD PMID:18172885 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of UGT1A6 mRNA CTD PMID:18500788 CGP 52608 multiple interactions ISO RGD:1349499 6480464 CGP 52608 promotes the reaction [RORA protein binds to UGT1A6 gene] CTD PMID:28238834 chenodeoxycholic acid decreases expression ISO RGD:1349499 6480464 Chenodeoxycholic Acid results in decreased expression of UGT1A6 mRNA CTD PMID:27174168 chlorohydrocarbon multiple interactions EXP 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of UGT1A6 mRNA CTD PMID:30744511 choline multiple interactions ISO RGD:1619652 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of UGT1A6B mRNA CTD PMID:20938992 chrysen-6-ol increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of 6-hydroxychrysene CTD PMID:7786300 chrysene increases expression ISO RGD:1349499 6480464 chrysene results in increased expression of UGT1A6 mRNA CTD PMID:15566942 chrysin affects glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein affects the glucuronidation of chrysin CTD PMID:10950852 ciglitazone multiple interactions ISO RGD:1349499 6480464 [ciglitazone binds to PPARG protein alternative form] which results in increased expression of UGT1A6 mRNA CTD PMID:16197558 cinnamyl alcohol increases expression ISO RGD:1349499 6480464 cinnamyl alcohol results in increased expression of UGT1A6 mRNA CTD PMID:20566472 ciprofibrate increases expression ISO RGD:1619652 6480464 ciprofibrate results in increased expression of UGT1A6 mRNA CTD PMID:19144771 cisplatin affects response to substance ISO RGD:1349499 6480464 UGT1A6 protein affects the susceptibility to Cisplatin CTD PMID:16217747 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of UGT1A6 mRNA, Clofibrate results in increased expression of UGT1A6 protein CTD PMID:11328961 , PMID:17967931 clofibrate increases expression ISO RGD:1619652 6480464 Clofibrate results in increased expression of UGT1A6 mRNA CTD PMID:19144771 cobalt dichloride decreases expression ISO RGD:1349499 6480464 cobaltous chloride results in decreased expression of UGT1A6 mRNA CTD PMID:19376846 copper(II) sulfate decreases expression ISO RGD:1349499 6480464 Copper Sulfate results in decreased expression of UGT1A6 mRNA CTD PMID:19549813 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of UGT1A6 mRNA CTD PMID:26577399 curcumin increases expression ISO RGD:1349499 6480464 Curcumin results in increased expression of UGT1A6 mRNA CTD PMID:16819192 cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Paraquat results in increased expression of UGT1A6 mRNA] CTD PMID:22846377 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of UGT1A6 mRNA CTD PMID:18172885 cyclosporin A decreases expression ISO RGD:1349499 6480464 Cyclosporine results in decreased expression of UGT1A6 mRNA CTD PMID:20106945 , PMID:27989131 cylindrospermopsin increases expression ISO RGD:1349499 6480464 cylindrospermopsin results in increased expression of UGT1A6 mRNA CTD PMID:23726867 cypermethrin affects expression ISO RGD:1619652 6480464 cypermethrin affects the expression of UGT1A6 mRNA CTD PMID:32214279 cypermethrin increases expression ISO RGD:1619652 6480464 cypermethrin results in increased expression of UGT1A6 CTD PMID:32214279 D-glucose multiple interactions ISO RGD:1349499 6480464 TPH1 protein affects the reaction [UGT1A6A protein affects the reaction [sodium arsenite inhibits the reaction [Glucose results in increased secretion of INS protein]]], UGT1A6A protein affects the reaction [sodium arsenite inhibits the reaction [Glucose results in increased secretion of INS protein]] CTD PMID:30562058 DDT decreases expression ISO RGD:1349499 6480464 DDT results in decreased expression of UGT1A6 mRNA CTD PMID:31521043 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of UGT1A6 mRNA CTD PMID:11328961 more ... dexamethasone multiple interactions ISO RGD:1619652 6480464 [Dexamethasone co-treated with Ibuprofen] results in increased expression of UGT1A6 mRNA CTD PMID:29222744 dexamethasone increases expression ISO RGD:1619652 6480464 Dexamethasone results in increased expression of UGT1A6 mRNA, Dexamethasone results in increased expression of UGT1A6B mRNA CTD PMID:22733784 , PMID:29222744 dexamethasone multiple interactions EXP 6480464 Dexamethasone promotes the reaction [benz(a)anthracene results in increased expression of UGT1A6 mRNA] CTD PMID:7587946 dextran sulfate multiple interactions ISO RGD:1619652 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of UGT1A6B mRNA CTD PMID:29950665 dextran sulfate decreases expression ISO RGD:1619652 6480464 Dextran Sulfate results in decreased expression of UGT1A6B mRNA CTD PMID:35093514 Diallyl sulfide multiple interactions EXP 6480464 allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of UGT1A6 mRNA], allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of UGT1A6 protein] CTD PMID:23494807 Diallyl sulfide increases expression ISO RGD:1619652 6480464 allyl sulfide results in increased expression of UGT1A6 mRNA CTD PMID:19144771 Diallyl sulfide increases expression EXP 6480464 allyl sulfide results in increased expression of UGT1A6 mRNA CTD PMID:19768707 diarsenic trioxide increases expression ISO RGD:1349499 6480464 Arsenic Trioxide results in increased expression of UGT1A6 mRNA CTD PMID:20458559 , PMID:29633893 dibenzo[a,l]pyrene increases expression ISO RGD:1349499 6480464 dibenzo(a, l)pyrene results in increased expression of UGT1A6 mRNA CTD PMID:15566942 dibenzo[a,l]pyrene multiple interactions ISO RGD:1349499 6480464 [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a, l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of UGT1A6 mRNA CTD PMID:15566942 diclofenac multiple interactions ISO RGD:1349499 6480464 Diclofenac inhibits the reaction [[UGT1A6 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] more ... CTD PMID:22265884 , PMID:33290829 dimethyl sulfoxide affects expression ISO RGD:1349499 6480464 Dimethyl Sulfoxide affects the expression of UGT1A6 mRNA CTD PMID:12843640 dimethylarsinous acid increases expression ISO RGD:1349499 6480464 dimethylarsinous acid results in increased expression of UGT1A6 mRNA CTD PMID:20886546 dioxygen affects expression ISO RGD:1349499 6480464 Oxygen deficiency affects the expression of UGT1A6 mRNA CTD PMID:33811995 dioxygen multiple interactions ISO RGD:1349499 6480464 [Acetaminophen co-treated with Oxygen deficiency] results in decreased expression of UGT1A6 mRNA more ... CTD PMID:33811995 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases expression ISO RGD:1349499 6480464 Antimony Potassium Tartrate results in increased expression of UGT1A6 mRNA CTD PMID:28713220 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate multiple interactions ISO RGD:1349499 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of UGT1A6 mRNA CTD PMID:32076005 disodium selenite increases expression ISO RGD:1349499 6480464 Sodium Selenite results in increased expression of UGT1A6 mRNA CTD PMID:18175754 disulfiram increases expression ISO RGD:1349499 6480464 Disulfiram results in increased expression of UGT1A6 mRNA CTD PMID:20566472 diuron increases expression EXP 6480464 Diuron results in increased expression of UGT1A6 mRNA CTD PMID:21551480 Erucin increases expression EXP 6480464 erucin results in increased expression of UGT1A6 protein CTD PMID:21132492 erythrosin B decreases activity ISO RGD:1349499 6480464 Erythrosine results in decreased activity of UGT1A6 protein CTD PMID:20041016 etofenprox multiple interactions EXP 6480464 [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA CTD PMID:22467020 eugenol increases expression ISO RGD:1349499 6480464 Eugenol results in increased expression of UGT1A6 mRNA CTD PMID:20566472 farnesol increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 felbamate increases expression EXP 6480464 felbamate results in increased expression of UGT1A6 mRNA CTD PMID:17381134 fenofibrate multiple interactions EXP 6480464 [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA CTD PMID:18253720 , PMID:18775883 fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of UGT1A6 mRNA CTD PMID:18775883 fenthion increases expression ISO RGD:1619652 6480464 Fenthion results in increased expression of UGT1A6B mRNA CTD PMID:34813904 finasteride increases expression EXP 6480464 Finasteride results in increased expression of UGT1A6 mRNA CTD PMID:24136188 fipronil increases expression EXP 6480464 fipronil results in increased expression of UGT1A6 mRNA CTD PMID:34044035 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of UGT1A6 mRNA CTD PMID:18035473 flurbiprofen increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of Flurbiprofen CTD PMID:15843492 flutamide increases expression EXP 6480464 Flutamide results in increased expression of UGT1A6 mRNA CTD PMID:24136188 , PMID:26485406 folic acid multiple interactions ISO RGD:1619652 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of UGT1A6B mRNA CTD PMID:20938992 fonofos decreases methylation ISO RGD:1349499 6480464 Fonofos results in decreased methylation of UGT1A6 promoter CTD PMID:22847954 galangin decreases activity ISO RGD:1349499 6480464 galangin results in decreased activity of UGT1A6 protein CTD PMID:35063619 gamma-hexachlorocyclohexane increases expression EXP 6480464 Hexachlorocyclohexane results in increased expression of UGT1A6 mRNA CTD PMID:17785943 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of UGT1A6 mRNA CTD PMID:24136188 glucose multiple interactions ISO RGD:1349499 6480464 TPH1 protein affects the reaction [UGT1A6A protein affects the reaction [sodium arsenite inhibits the reaction [Glucose results in increased secretion of INS protein]]], UGT1A6A protein affects the reaction [sodium arsenite inhibits the reaction [Glucose results in increased secretion of INS protein]] CTD PMID:30562058 glutathione increases expression EXP 6480464 Glutathione deficiency results in increased expression of UGT1A6 mRNA CTD PMID:15345336 Hexachloro-1,3-butadiene increases expression EXP 6480464 hexachlorobutadiene results in increased expression of UGT1A6 mRNA CTD PMID:21905055 hydroquinone increases metabolic processing EXP 6480464 UGT1A6 protein results in increased metabolism of hydroquinone CTD PMID:9118891 ibuprofen increases expression ISO RGD:1619652 6480464 Ibuprofen results in increased expression of UGT1A6 mRNA CTD PMID:29222744 ibuprofen multiple interactions ISO RGD:1619652 6480464 [Dexamethasone co-treated with Ibuprofen] results in increased expression of UGT1A6 mRNA CTD PMID:29222744 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of UGT1A6 mRNA CTD PMID:21396975 indole-3-methanol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA, Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA] CTD PMID:22129741 indometacin multiple interactions ISO RGD:1349499 6480464 Indomethacin inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol] CTD PMID:22265884 indoxyl sulfate increases expression ISO RGD:1349499 6480464 Indican results in increased expression of UGT1A6 mRNA CTD PMID:20000589 irinotecan increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of Irinotecan CTD PMID:15716465 iron atom multiple interactions EXP 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of UGT1A6 mRNA CTD PMID:22198552 iron(0) multiple interactions EXP 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of UGT1A6 mRNA CTD PMID:22198552 isoeugenol increases expression ISO RGD:1349499 6480464 isoeugenol results in increased expression of UGT1A6 mRNA CTD PMID:20566472 ketoprofen affects metabolic processing EXP 6480464 UGT1A6 protein affects the metabolism of Ketoprofen CTD PMID:15336321 ketoprofen increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of Ketoprofen CTD PMID:15843492 kojic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of UGT1A6 mRNA CTD PMID:18544905 L-ascorbic acid multiple interactions EXP 6480464 UGT1A6 protein affects the reaction [Methylcholanthrene results in increased abundance of Ascorbic Acid] CTD PMID:8263600 L-methionine multiple interactions ISO RGD:1619652 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of UGT1A6B mRNA CTD PMID:20938992 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of UGT1A6 mRNA CTD PMID:24136188 Licochalcone A multiple interactions ISO RGD:1349499 6480464 licochalcone A inhibits the reaction [Hymecromone results in increased activity of UGT1A6 protein] CTD PMID:26875642 lorcaserin multiple interactions ISO RGD:1349499 6480464 UGT1A6 protein results in increased carbamoylation of and results in increased glucuronidation of lorcaserin CTD PMID:22259019 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [ferric 8-hydroxyquinoline results in increased expression of UGT1A6 mRNA], Melatonin inhibits the reaction [Paraquat results in increased expression of UGT1A6 mRNA] CTD PMID:22846377 menadione multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of UGT1A6 promoter] CTD PMID:15336321 menadione increases expression EXP 6480464 Vitamin K 3 results in increased expression of UGT1A6 mRNA CTD PMID:15336321 , PMID:22846377 menadione increases activity EXP 6480464 Vitamin K 3 results in increased activity of UGT1A6 promoter CTD PMID:15336321 metazachlor increases expression EXP 6480464 metazachlor results in increased expression of UGT1A6 mRNA CTD PMID:31465819 methotrexate increases expression ISO RGD:1349499 6480464 Methotrexate results in increased expression of UGT1A6 mRNA CTD PMID:20854796 methotrexate decreases expression ISO RGD:1349499 6480464 Methotrexate results in decreased expression of UGT1A6 mRNA CTD PMID:24449571 methotrexate decreases response to substance ISO RGD:1349499 6480464 UGT1A6 protein results in decreased susceptibility to Methotrexate CTD PMID:20854796 methyl salicylate increases metabolic processing EXP 6480464 UGT1A6 protein results in increased metabolism of methyl salicylate CTD PMID:9429234 methyl salicylate affects metabolic processing EXP 6480464 UGT1A6 gene polymorphism affects the metabolism of methyl salicylate CTD PMID:9429234 methylmercury chloride multiple interactions EXP 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of UGT1A6 mRNA CTD PMID:30744511 morin decreases activity ISO RGD:1349499 6480464 morin results in decreased activity of UGT1A6 protein CTD PMID:35063619 morphine increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of Morphine CTD PMID:12920162 myricetin decreases activity ISO RGD:1349499 6480464 myricetin results in decreased activity of UGT1A6 protein CTD PMID:35063619 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA], Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of UGT1A6 promoter] CTD PMID:15336321 , PMID:22129741 N-acetylserotonin multiple interactions ISO RGD:1349499 6480464 methyl 2-(2-acetoxy-6 more ... CTD PMID:34910929 N-acetylserotonin increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of N-acetylserotonin CTD PMID:34910929 N-butyl-N-(4-hydroxybutyl)nitrosamine multiple interactions ISO RGD:1619652 6480464 oltipraz inhibits the reaction [Butylhydroxybutylnitrosamine results in decreased expression of UGT1A6 mRNA] CTD PMID:15374950 N-butyl-N-(4-hydroxybutyl)nitrosamine decreases expression ISO RGD:1619652 6480464 Butylhydroxybutylnitrosamine results in decreased expression of UGT1A6 mRNA CTD PMID:15374950 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UGT1A6 mRNA more ... CTD PMID:18164116 more ... N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of UGT1A6 mRNA, Diethylnitrosamine results in decreased expression of UGT1A6 protein CTD PMID:23494807 N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of UGT1A6 mRNA CTD PMID:19716841 naproxen increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of Naproxen CTD PMID:15843492 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of UGT1A6 mRNA CTD PMID:24136188 nickel atom multiple interactions EXP 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of UGT1A6 mRNA CTD PMID:22198552 nickel sulfate increases expression ISO RGD:1349499 6480464 nickel sulfate results in increased expression of UGT1A6 mRNA CTD PMID:20566472 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of UGT1A6 mRNA CTD PMID:24136188 Nor-9-carboxy-delta9-THC multiple interactions ISO RGD:1349499 6480464 [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of UGT1A6 gene CTD PMID:30521419 obeticholic acid decreases expression ISO RGD:1349499 6480464 obeticholic acid results in decreased expression of UGT1A6 mRNA CTD PMID:27939613 ochratoxin A increases expression ISO RGD:1349499 6480464 ochratoxin A results in increased expression of UGT1A6 mRNA CTD PMID:17316727 oltipraz multiple interactions ISO RGD:1619652 6480464 oltipraz inhibits the reaction [Butylhydroxybutylnitrosamine results in decreased expression of UGT1A6 mRNA] CTD PMID:15374950 oltipraz increases expression ISO RGD:1619652 6480464 oltipraz results in increased expression of UGT1A6 mRNA CTD PMID:15374950 , PMID:19144771 omeprazole increases expression EXP 6480464 Omeprazole results in increased expression of UGT1A6 mRNA CTD PMID:19118567 omeprazole increases expression ISO RGD:1349499 6480464 Omeprazole results in increased expression of UGT1A6 mRNA CTD PMID:19118567 omeprazole multiple interactions EXP 6480464 [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA CTD PMID:22687989 osimertinib decreases activity ISO RGD:1349499 6480464 osimertinib results in decreased activity of UGT1A6 protein CTD PMID:34044055 oxybenzone decreases expression EXP 6480464 oxybenzone results in decreased expression of UGT1A6 mRNA CTD PMID:30316929 ozone multiple interactions ISO RGD:1619652 6480464 [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of UGT1A6B mRNA CTD PMID:34911549 p-cresol increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of 4-cresol CTD PMID:32421801 p-cresol multiple interactions ISO RGD:1349499 6480464 Acetaminophen inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 4-cresol], amentoflavone inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 4-cresol] CTD PMID:32421801 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of UGT1A6 mRNA CTD PMID:12883083 paracetamol increases expression ISO RGD:1349499 6480464 Acetaminophen results in increased expression of UGT1A6 mRNA CTD PMID:33811995 paracetamol decreases activity ISO RGD:1349499 6480464 Acetaminophen results in decreased activity of UGT1A6 protein CTD PMID:32421801 paracetamol decreases expression ISO RGD:1349499 6480464 Acetaminophen results in decreased expression of UGT1A6 mRNA CTD PMID:29067470 paracetamol multiple interactions ISO RGD:1349499 6480464 [Acetaminophen co-treated with Oxygen deficiency] results in decreased expression of UGT1A6 mRNA more ... CTD PMID:32421801 , PMID:33811995 paracetamol increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of Acetaminophen CTD PMID:11186135 more ... paracetamol affects glucuronidation ISO RGD:1349499 6480464 UGT1A6 gene polymorphism affects the glucuronidation of Acetaminophen CTD PMID:15761113 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of UGT1A6 mRNA CTD PMID:33387578 paracetamol increases glucuronidation ISO RGD:1619652 6480464 UGT1A6 protein results in increased glucuronidation of Acetaminophen CTD PMID:11903872 paracetamol decreases activity ISO RGD:1619652 6480464 Acetaminophen results in decreased activity of UGT1A6 protein CTD PMID:16831125 paracetamol multiple interactions ISO RGD:1619652 6480464 [NFE2L2 protein affects the expression of UGT1A6 mRNA] which affects the susceptibility to Acetaminophen more ... CTD PMID:11134556 more ... paracetamol decreases expression ISO RGD:1619652 6480464 Acetaminophen results in decreased expression of UGT1A6 mRNA CTD PMID:26772156 paraquat multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Paraquat results in increased expression of UGT1A6 mRNA] more ... CTD PMID:19023562 , PMID:22846377 paraquat increases expression EXP 6480464 Paraquat results in increased expression of UGT1A6 mRNA CTD PMID:19023562 , PMID:22846377 parathion decreases methylation ISO RGD:1349499 6480464 Parathion results in decreased methylation of UGT1A6 promoter CTD PMID:22847954 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of UGT1A6 mRNA CTD PMID:19162173 phenanthrene multiple interactions ISO RGD:1349499 6480464 [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a, l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of UGT1A6 mRNA CTD PMID:15566942 phenethyl isothiocyanate increases expression EXP 6480464 phenethyl isothiocyanate results in increased expression of UGT1A6 protein CTD PMID:21132492 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of UGT1A6 mRNA, Phenobarbital results in increased expression of UGT1A6 protein CTD PMID:17381134 more ... phenobarbital decreases expression ISO RGD:1349499 6480464 Phenobarbital results in decreased expression of UGT1A6 protein CTD PMID:28541575 phenobarbital multiple interactions EXP 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Phenobarbital promotes the reaction [Benzo(a)pyrene results in increased expression of UGT1A6 mRNA]], Phenobarbital promotes the reaction [Benzo(a)pyrene results in increased expression of UGT1A6 mRNA] CTD PMID:25489928 phenol increases metabolic processing EXP 6480464 UGT1A6 protein results in increased metabolism of Phenol CTD PMID:9118891 phenytoin increases expression EXP 6480464 Phenytoin results in increased expression of UGT1A6 mRNA CTD PMID:17381134 pirinixic acid increases expression ISO RGD:1619652 6480464 pirinixic acid results in increased expression of UGT1A6 mRNA CTD PMID:17151188 pirinixic acid increases expression ISO RGD:1349499 6480464 pirinixic acid results in increased expression of UGT1A6 mRNA, pirinixic acid results in increased expression of UGT1A6 protein CTD PMID:17151188 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:1619652 6480464 Pregnenolone Carbonitrile results in increased expression of UGT1A6 mRNA CTD PMID:19144771 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:1349499 6480464 Pregnenolone Carbonitrile results in increased expression of UGT1A6 mRNA, Pregnenolone Carbonitrile results in increased expression of UGT1A6 protein CTD PMID:16155002 pterostilbene multiple interactions ISO RGD:1349499 6480464 pterostilbene inhibits the reaction [[UGT1A6 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 pterostilbene decreases activity ISO RGD:1349499 6480464 pterostilbene results in decreased activity of UGT1A6 protein CTD PMID:31812603 puerarin increases metabolic processing ISO RGD:1349499 6480464 UGT1A6 protein results in increased metabolism of puerarin CTD PMID:22648071 pyrene decreases expression ISO RGD:1619652 6480464 pyrene results in decreased expression of UGT1A6 mRNA CTD PMID:26160115 pyrene multiple interactions ISO RGD:1349499 6480464 [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a, l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of UGT1A6 mRNA CTD PMID:15566942 quercetin increases expression ISO RGD:1619652 6480464 Quercetin results in increased expression of UGT1A6 mRNA CTD PMID:22334599 quercetin increases expression ISO RGD:1349499 6480464 Quercetin results in increased expression of UGT1A6 mRNA CTD PMID:18094037 quercetin decreases activity ISO RGD:1349499 6480464 Quercetin results in decreased activity of UGT1A6 protein CTD PMID:35063619 quercetin 3-O-beta-D-galactopyranoside multiple interactions ISO RGD:1619652 6480464 hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT1A6 mRNA] CTD PMID:26772156 rifampicin increases expression ISO RGD:1349499 6480464 Rifampin results in increased expression of UGT1A6 mRNA CTD PMID:18094037 rose bengal decreases activity ISO RGD:1349499 6480464 Rose Bengal results in decreased activity of UGT1A6 protein CTD PMID:20041016 rotenone affects expression ISO RGD:1619652 6480464 Rotenone affects the expression of UGT1A6B mRNA CTD PMID:23186747 scopoletin increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of Scopoletin CTD PMID:15802387 serotonin increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of Serotonin, UGT1A6 protein results in increased glucuronidation of Serotonin metabolite CTD PMID:15761113 more ... serotonin affects glucuronidation ISO RGD:1349499 6480464 UGT1A6 gene polymorphism affects the glucuronidation of Serotonin, UGT1A6 gene polymorphism affects the glucuronidation of Serotonin metabolite CTD PMID:15761113 serotonin multiple interactions ISO RGD:1349499 6480464 bisphenol A inhibits the reaction [UGT1A6 protein results in increased glucuronidation of Serotonin] CTD PMID:18214896 sevoflurane affects expression EXP 6480464 sevoflurane affects the expression of UGT1A6 mRNA CTD PMID:15967596 silibinin decreases activity EXP 6480464 Silybin metabolite results in decreased activity of UGT1A6 protein CTD PMID:15921999 silibinin multiple interactions ISO RGD:1349499 6480464 Silybin inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin] CTD PMID:15155549 silicon dioxide decreases expression ISO RGD:1349499 6480464 Silicon Dioxide analog results in decreased expression of UGT1A6 mRNA CTD PMID:25895662 sodium arsenate multiple interactions ISO RGD:1349499 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of UGT1A6 mRNA CTD PMID:32525701 sodium arsenite increases expression ISO RGD:1349499 6480464 sodium arsenite results in increased expression of UGT1A6 mRNA CTD PMID:24570342 more ... sodium arsenite decreases methylation ISO RGD:1349499 6480464 sodium arsenite results in decreased methylation of UGT1A6 gene CTD PMID:24570342 sodium arsenite multiple interactions ISO RGD:1349499 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of UGT1A6 mRNA more ... CTD PMID:30562058 , PMID:32076005 spermidine increases expression ISO RGD:1619652 6480464 Spermidine results in increased expression of UGT1A6 mRNA CTD PMID:12763045 spermidine multiple interactions ISO RGD:1619652 6480464 pimagedine inhibits the reaction [Spermidine results in increased expression of UGT1A6 mRNA] CTD PMID:12763045 spironolactone increases expression ISO RGD:1619652 6480464 Spironolactone results in increased expression of UGT1A6 mRNA CTD PMID:19144771 terbufos decreases methylation ISO RGD:1349499 6480464 terbufos results in decreased methylation of UGT1A6 promoter CTD PMID:22847954 testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of UGT1A6 mRNA CTD PMID:32741896 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of UGT1A6 mRNA, Carbon Tetrachloride affects the expression of UGT1A6 protein CTD PMID:32380060 tetracycline decreases expression EXP 6480464 Tetracycline results in decreased expression of UGT1A6 mRNA CTD PMID:19224547 tetraphene increases expression EXP 6480464 benz(a)anthracene results in increased expression of UGT1A6 mRNA CTD PMID:7587946 tetraphene multiple interactions EXP 6480464 Dexamethasone promotes the reaction [benz(a)anthracene results in increased expression of UGT1A6 mRNA] CTD PMID:7587946 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of UGT1A6 mRNA CTD PMID:23411599 titanium dioxide increases expression ISO RGD:1619652 6480464 titanium dioxide results in increased expression of UGT1A6B mRNA CTD PMID:23557971 titanium dioxide multiple interactions ISO RGD:1619652 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of UGT1A6B mRNA CTD PMID:29950665 trans-isoeugenol increases expression ISO RGD:1349499 6480464 isoeugenol results in increased expression of UGT1A6 mRNA CTD PMID:20566472 triadimefon increases expression EXP 6480464 triadimefon results in increased expression of UGT1A6 mRNA CTD PMID:16643972 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of UGT1A6 mRNA CTD PMID:33387578 triclocarban multiple interactions ISO RGD:1349499 6480464 NR1I3 gene mutant form inhibits the reaction [triclocarban results in increased expression of UGT1A6 mRNA] CTD PMID:22761658 triclocarban increases expression ISO RGD:1349499 6480464 triclocarban results in increased expression of UGT1A6 mRNA CTD PMID:22761658 trifluralin increases expression EXP 6480464 Trifluralin results in increased expression of UGT1A6 mRNA CTD PMID:18582544 tungsten multiple interactions EXP 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of UGT1A6 mRNA CTD PMID:22198552 umbelliferone affects metabolic processing EXP 6480464 UGT1A6 gene polymorphism affects the metabolism of 7-hydroxycoumarin CTD PMID:9429234 umbelliferone increases metabolic processing EXP 6480464 UGT1A6 protein results in increased metabolism of 7-hydroxycoumarin CTD PMID:9429234 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of UGT1A6 mRNA CTD PMID:24136188 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of UGT1A6 mRNA CTD PMID:17381134 valproic acid decreases expression ISO RGD:1349499 6480464 Valproic Acid results in decreased expression of UGT1A6 mRNA CTD PMID:29501571 valproic acid increases glucuronidation ISO RGD:1349499 6480464 UGT1A6 protein results in increased glucuronidation of Valproic Acid CTD PMID:15761113 valproic acid affects glucuronidation ISO RGD:1349499 6480464 UGT1A6 gene polymorphism affects the glucuronidation of Valproic Acid CTD PMID:15761113 xanthenes decreases activity ISO RGD:1349499 6480464 Xanthenes results in decreased activity of UGT1A6 protein CTD PMID:18686201 , PMID:20041016 zoledronic acid decreases expression ISO RGD:1349499 6480464 Zoledronic Acid results in decreased expression of UGT1A6 mRNA CTD PMID:24714768
