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Gene: Dct (dopachrome tautomerase) Rattus norvegicus
Symbol: Dct
Name: dopachrome tautomerase
RGD ID: 1564975
Description: Predicted to have dopachrome isomerase activity. Predicted to be involved in several processes, including generation of neurons; melanin biosynthetic process from tyrosine; and response to blue light. Predicted to localize to several cellular components, including cytosol; melanosome; and plasma membrane. Orthologous to human DCT (dopachrome tautomerase); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; INTERACTS WITH bisphenol A; diuron; glycidol.
Type: protein-coding
RefSeq Status: MODEL
Also known as: dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2); L-dopachrome tautomerase; LOC290484; LOW QUALITY PROTEIN: L-dopachrome tautomerase; RGD1564975; similar to Dopachrome tautomerase
Homo sapiens (human) : DCT (dopachrome tautomerase)  HGNC  Alliance
Mus musculus (house mouse) : Dct (dopachrome tautomerase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dct (dopachrome tautomerase)
Pan paniscus (bonobo/pygmy chimpanzee) : DCT (dopachrome tautomerase)
Canis lupus familiaris (dog) : DCT (dopachrome tautomerase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dct (dopachrome tautomerase)
Sus scrofa (pig) : DCT (dopachrome tautomerase)
Chlorocebus sabaeus (African green monkey) : DCT (dopachrome tautomerase)
Heterocephalus glaber (naked mole-rat) : Dct (dopachrome tautomerase)
more info ...
Is Marker For: Strains:   F344-Tg(Dct-lacZ)9Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.015103,208,174 - 103,245,033 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15103,208,258 - 103,244,494 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015106,647,067 - 106,681,458 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415102,798,699 - 102,832,240 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1593,915,976 - 93,952,737 (-)NCBICelera
Cytogenetic Map15q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Dct
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1564975
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.