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Gene: Dct (dopachrome tautomerase) Rattus norvegicus
Symbol: Dct
Name: dopachrome tautomerase
Description: Predicted to have dopachrome isomerase activity. Predicted to be involved in several processes, including developmental pigmentation; generation of neurons; and melanin biosynthetic process from tyrosine. Predicted to localize to the cytosol and melanosome. Orthologous to human DCT (dopachrome tautomerase); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; INTERACTS WITH bisphenol A; diuron; glycidol.
Type: protein-coding
RefSeq Status: MODEL
Also known as: dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2); L-dopachrome tautomerase; LOC290484; LOW QUALITY PROTEIN: L-dopachrome tautomerase; RGD1564975; similar to Dopachrome tautomerase
Homo sapiens (human) : DCT (dopachrome tautomerase)  HGNC  Alliance
Mus musculus (house mouse) : Dct (dopachrome tautomerase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dct (dopachrome tautomerase)
Pan paniscus (bonobo/pygmy chimpanzee) : DCT (dopachrome tautomerase)
Canis lupus familiaris (dog) : DCT (dopachrome tautomerase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dct (dopachrome tautomerase)
Sus scrofa (pig) : DCT (dopachrome tautomerase)
more info ...
Is Marker For: Strains:   F344-Tg(Dct-lacZ)9Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.015103,208,174 - 103,245,033 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.015106,647,067 - 106,681,458 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415102,798,699 - 102,832,240 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1593,915,976 - 93,952,737 (-)NCBICelera
Cytogenetic Map15q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Dct
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1564975
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.