Gene: Dusp1 (dual specificity phosphatase 1) Rattus norvegicus
Analyze
Symbol: Dusp1
Name: dual specificity phosphatase 1
Description: ENCODES a protein that exhibits growth factor binding; protein tyrosine/threonine phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity (ortholog); INVOLVED IN cellular response to hormone stimulus; intracellular signal transduction; negative regulation of apoptotic process; PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; angiotensin II signaling pathway via AT2 receptor; ASSOCIATED WITH anti-basement membrane glomerulonephritis; Carotid Artery Injuries; Diabetes Mellitus, Experimental ; FOUND IN nucleus; cytoplasm (ortholog); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3CH134; 3CH134/CL100 PTPase; CL100; dual specificity phosphatase; dual specificity protein phosphatase 1; MAP kinase phosphatase 1; Map kinase phosphatase-1; mitogen-activated protein (MAP) kinase phosphatase-1; mitogen-activated protein kinase phosphatase 1; Mkp-1; Mkp1; oxidative stress-inducible protein tyrosine phosphatase; protein tyrosine phosphatase non-receptor type 16; protein tyrosine phosphatase, non-receptor type 16; protein-tyrosine phosphatase CL100; protein-tyrosine phosphatase non-receptor type 16; Ptpn16
Orthologs:
Homo sapiens (human) : DUSP1 (dual specificity phosphatase 1)  HGNC  Alliance
Mus musculus (house mouse) : Dusp1 (dual specificity phosphatase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp1 (dual specificity phosphatase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP1 (dual specificity phosphatase 1)
Canis lupus familiaris (dog) : DUSP1 (dual specificity phosphatase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp1 (dual specificity phosphatase 1)
Sus scrofa (pig) : DUSP1 (dual specificity phosphatase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01016,970,642 - 16,973,425 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01016,867,381 - 16,870,164 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41016,942,913 - 16,945,696 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11016,943,975 - 16,946,743 (+)NCBI
Celera1016,333,248 - 16,336,031 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dusp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620897
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE