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Gene: Abcc1 (ATP binding cassette subfamily C member 1) Rattus norvegicus
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Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Description: Exhibits long-chain fatty acid transporter activity and transmembrane transporter activity. Involved in several processes, including negative regulation of neuron death; organic anion transport; and xenobiotic detoxification by transmembrane export across the plasma membrane. Localizes to basal plasma membrane; cytoplasm; and integral component of plasma membrane. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease. Orthologous to human ABCC1 (ATP binding cassette subfamily C member 1); PARTICIPATES IN docetaxel pharmacodynamics pathway; doxorubicin pharmacokinetics pathway; irinotecan pharmacodynamics pathway; INTERACTS WITH (+)-pilocarpine; (R)-adrenaline; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Abcc1a; ATP-binding cassette sub-family C ( CFTR/MRP) member 1a; ATP-binding cassette sub-family C (CFTR/MRP) member 1 (multiple drug resistance-associated protein); ATP-binding cassette sub-family C member 1; ATP-binding cassette, sub-family C ( CFTR/MRP), member 1a; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C, member 1-like; ATP-binding cassette, subfamily C (CFTR/MRP), member 1; Avcc1a; glutathione-S-conjugate-translocating ATPase ABCC1; leukotriene C(4) transporter; LOC100362747; LOC100365034; LTC4 transporter; Mrp; Mrp1; multidrug resistance protein; Multidrug resistance protein 1; multidrug resistance-associated protein 1; multidrug resistance-associated protein 1-like; multiple drug resistance-associated protein
Orthologs:
Homo sapiens (human) : ABCC1 (ATP binding cassette subfamily C member 1)  HGNC  Alliance
Mus musculus (house mouse) : Abcc1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcc1 (ATP binding cassette subfamily C member 1)
Canis lupus familiaris (dog) : ABCC1 (ATP binding cassette subfamily C member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc1 (ATP binding cassette subfamily C member 1)
Sus scrofa (pig) : ABCC1 (ATP binding cassette subfamily C member 1)
Chlorocebus sabaeus (African green monkey) : ABCC1 (ATP binding cassette subfamily C member 1)
Heterocephalus glaber (naked mole-rat) : Abcc1 (ATP binding cassette subfamily C member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010549,537 - 672,235 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10549,883 - 672,196 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01011,232,233 - 11,354,931 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410452,239 - 575,705 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110452,238 - 575,705 (-)NCBI
Celera1011,130,945 - 11,246,232 (-)NCBICelera
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Annotation    (Toggle Annotation Detail/Summary View)

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References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Abcc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3112
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.