Gene: Abcc1 (ATP binding cassette subfamily C member 1) Rattus norvegicus
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Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Description: ENCODES a protein that exhibits drug transmembrane transporter activity; efflux transmembrane transporter activity; glutathione S-conjugate-exporting ATPase activity; INVOLVED IN cell chemotaxis; drug export; drug transmembrane transport; PARTICIPATES IN docetaxel pharmacodynamics pathway; doxorubicin pharmacokinetics pathway; irinotecan pharmacodynamics pathway; ASSOCIATED WITH asthma (ortholog); breast cancer, familial (ortholog); Breast Neoplasms (ortholog); FOUND IN basolateral plasma membrane; cytoplasm; integral component of plasma membrane; INTERACTS WITH (+)-pilocarpine; (R)-adrenaline; 17beta-estradiol 3-benzoate
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Abcc1a; ATP-binding cassette sub-family C ( CFTR/MRP) member 1a; ATP-binding cassette sub-family C (CFTR/MRP) member 1 (multiple drug resistance-associated protein); ATP-binding cassette sub-family C member 1; ATP-binding cassette, sub-family C ( CFTR/MRP), member 1a; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C, member 1-like; ATP-binding cassette, subfamily C (CFTR/MRP), member 1; Avcc1a; leukotriene C(4) transporter; LOC100362747; LOC100365034; LTC4 transporter; Mrp; Mrp1; multidrug resistance protein; Multidrug resistance protein 1; multidrug resistance-associated protein 1; multidrug resistance-associated protein 1-like; multiple drug resistance-associated protein
Orthologs:
Homo sapiens (human) : ABCC1 (ATP binding cassette subfamily C member 1)  HGNC  Alliance
Mus musculus (house mouse) : Abcc1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcc1 (ATP binding cassette subfamily C member 1)
Canis lupus familiaris (dog) : ABCC1 (ATP binding cassette subfamily C member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc1 (ATP binding cassette subfamily C member 1)
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Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010549,537 - 672,235 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01011,232,233 - 11,354,931 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410452,239 - 575,705 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110452,238 - 575,705 (-)NCBI
Celera1011,130,945 - 11,246,232 (-)NCBICelera
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Abcc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3112
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE



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